One new isobenzofuranone derivative, 1,4-dimethoxy-3-(3R*-hydroxy-3R*-methyl-1-tetralone)-1 (3H)-isobenzofuran (1), was isolated from the broth of marine Streptomyces sp. M268. The structure was elucidated by ...One new isobenzofuranone derivative, 1,4-dimethoxy-3-(3R*-hydroxy-3R*-methyl-1-tetralone)-1 (3H)-isobenzofuran (1), was isolated from the broth of marine Streptomyces sp. M268. The structure was elucidated by spectroscopy characteristics as well as comparison with the literature. Compound 1 exhibited cytotoxicities against human cancer cell, HL-60, A549, and BEL-7402.展开更多
A new degraded sesquiterpene was isolated from the marine actinomycete Streptomyces sp. 0616208. Its structure was elucidated as (1α; 4aα; 5α, 7β, 8aβ)-5, 8a-dimethyl-decahydrona- phthalene-1, 4a, 7-triol on th...A new degraded sesquiterpene was isolated from the marine actinomycete Streptomyces sp. 0616208. Its structure was elucidated as (1α; 4aα; 5α, 7β, 8aβ)-5, 8a-dimethyl-decahydrona- phthalene-1, 4a, 7-triol on the basis of spectroscopic data.展开更多
基金supported by the Public Science and Technology Research Funds Projects of Ocean (No.200905021-3)the National Natural Science Foundation of China (No. 31000037)+1 种基金the Key Knowledge Innovation Project of Chinese Academy of Science (No. KZCX2-YW-JC201)the National Science & Technology Pillar Program of China (No. 2011BAE06B004-05)
文摘One new isobenzofuranone derivative, 1,4-dimethoxy-3-(3R*-hydroxy-3R*-methyl-1-tetralone)-1 (3H)-isobenzofuran (1), was isolated from the broth of marine Streptomyces sp. M268. The structure was elucidated by spectroscopy characteristics as well as comparison with the literature. Compound 1 exhibited cytotoxicities against human cancer cell, HL-60, A549, and BEL-7402.
文摘A new degraded sesquiterpene was isolated from the marine actinomycete Streptomyces sp. 0616208. Its structure was elucidated as (1α; 4aα; 5α, 7β, 8aβ)-5, 8a-dimethyl-decahydrona- phthalene-1, 4a, 7-triol on the basis of spectroscopic data.