Enabling dendrite-free charging for lithium batteries based on transport-reaction competition mechanism in CHAIN framework

Worldwide trends in mobile electrification will skyrocket demands for lithium-based battery production,driven by the popularity of electric vehicles.However,both lithium metal batteries and lithium ion batteries face severe safety issues due to dendrite nucleation and growth process.Li deposition is significantly influenced by interfacial factors and charging conditions.In this paper,an electrochemical model considering the internal and external factors is proposed based on Monte Carlo method.The influence of internal solid electrolyte interphase(SEI)porosity,thickness and the external conditions on dendrite growth process is systematically described.The simulation results support that the three factors investigated in this model could synergistically regulate the dendrite growth process.Three competition mechanisms are proposed to tailor lithium deposition for Li-based batteries and numerical solutions for variation pattern of dendrite growth with time are fitted.A three-step process describing kinetic process of lithium deposition is proposed.To achieve dendrite-free charging process,charging strategies and emerging materials design should be considered,including physicochemical materials engineering,artificial SEI,and design for dynamic safety boundary.This work could contribute to the foundation for insights of Li deposition mechanism,which is promising to provide guidelines for next-generation high-energy-density and safe batteries in CHAIN framework.

Perfecting the Market-Oriented Ecological Compensation Mechanism of Ethnic Minority Areas: A Case Study of Gannan Tibetan Autonomous Prefecture

The construction of the market-oriented ecological compensation mechanism in China is complicated system engineering. China's ecological compensation funds are mainly derived from the public finance, lacking market-oriented operation. That not only increases the financial burden of the government, but also leads to the incomprehensive compensation scope. Moreover, China's ecological compensation lacks market mechanism so that it is difficult to set compensation standards and calculate offsets. This paper takes Gannan Tibetan Autonomous Prefecture as an example to analyze the market-oriented ecological compensation system of ethnic minority areas from the perspective of market economy, so as to provide a theoretical basis and a reference point for the establishment of efficient and reasonable ecological compensation mechanism and policies in ethnic minority areas and provide environmental protection for the sustainable development of economy and society of ethnic minority areas.

Strategies for Applying the Talented Personnel Competition Mechanism in the Commercial Age

With the increasingly fiercer talented personnel competition, the introduction of a talented personnel competition mechanism has become imperative in the commercial age. In this paper, the necessities of introducing a talented personnel competition mechanism are analyzed, and then the guiding ideology and principles of the talented personnel competition mechanism are proposed, and finally the application strategies of the talented personnel competition mechanism are discussed

Mechanism of Competition between Nutlin3 and p53 for Binding with Mdm2

The tumour suppressor p53 is a transcription factor that regulates multiple biological functions including metabolism, DNA repair, cell cycle arrest, apoptosis and senescence. About half of human cancers show a normal TP53 gene and aberrant overexpression of Mdm2. This fact promotes a promising cancer therapeutic strategy by inhibiting the interactions between p53 and Mdm2. Various inhibitors have been designed to achieve this novel approach for cancer therapy. However, the detailed competition mechanism between these inhibitors and the p53 molecule in their binding process to Mdm2 is still unclear. We investigate this competition mechanism between Nutlin3 and p53 using molecular dynamics simulations. It is found that Nutlin3 binds faster than the p53 molecule to Mdm2 to prevent p53 binding to Mdm2 when Nutlin3 and p53 have equal distance from Mdm2. Nutlin3 can also bind to the p53-Mdm2 complex to disturb and weaken the interactions between p53 and Mdm2. Consequently, p53 cannot bind to Mdm2 and its tumour suppression function is reactivated. These results provide the detailed competition mechanism between Nutlin3 and p53 in their binding to Mdm2. Because the binding site of most other inhibitors to Mdm2 is the same as Nutlin3, therefore this competition mechanism can extend to most inhibitors which target the p53-Mdm2 interaction.

Market-Oriented Electricity Pricing Mechanism Should be Eagerly Set Up in China

Electricity pricing is the core of the power institutional reform in China, which is related to not onlyinterests redistribution of all parties, but also health and security of the entire power industry. Only byaccelerating the reform on pricing mechanism can sound development of the power industry be promoted.

Mechanism transformation of cyclohexene-thiophene competitive adsorption in FAU zeolite

Competition of hydrocarbon compounds with sulfides in gasoline has caused a not very high selectivity of sulfides in adsorption desulfurization so far,resulting in a reduction of catalyst lifetime as well as more sulfur oxide emissions.Tostudy the whole competitive process changing with the increase of the loading,the dynamic competition adsorption mechanism of cyclohexene and thiophene in siliceous faujasite(FAU)zeolite was analyzed by the Monte Carlo simulation.The results showed that with the increase of the loading,thiophene and cyclohexene had different performances before and after the inflection point of 40 molecule/UC.The adsorbates were distributed ideally at optimal sites during the stage that occurred before the inflection point,which is called the“optimal-displacement adsorption”stage.When approaching the inflection point,the competition became apparent and the displacement appeared accordingly,some thiophene molecules at S sites(refers to the sites inside the supercages)were displaced by cyclohexene.After the inflection point,the concentration of adsorbates at W sites(refers to the 12-membered ring connecting the supercages)was significantly reduced,whereas the adsorbates at S sites got more concentrated.The stage some cyclohexene molecules displaced by thiophene and inserted into the center of the supercage can be named as the“insertion-displacement adsorption”stage,and both the adsorption behavior and the competitive relationship became localized when the adsorption amount became saturated.This shift in the competitive adsorption mechanism was due to the sharp increase of interaction energy between the adsorbates.Besides,the increase in temperature and ratio of Si/Al will allow the adsorbates,especially thiophene molecules to occupy more adsorption sites,and it is beneficial to improve the desulfurization selectivity.

Machining Parameters Optimization of Multi-Pass Face Milling Using a Chaotic Imperialist Competitive Algorithm with an Efficient Constraint-Handling Mechanism

The selection of machining parameters directly affects the production time,quality,cost,and other process performance measures for multi-pass milling.Optimization of machining parameters is of great significance.However,it is a nonlinear constrained optimization problem,which is very difficult to obtain satisfactory solutions by traditional optimization methods.A new optimization technique combined chaotic operator and imperialist competitive algorithm(ICA)is proposed to solve this problem.The ICA simulates the competition between the empires.It is a population-based meta-heuristic algorithm for unconstrained optimization problems.Imperialist development operator based on chaotic sequence is introduced to improve the local search of ICA,while constraints handling mechanism is introduced and an imperialist-colony transformation policy is established.The improved ICA is called chaotic imperialist competitive algorithm(CICA).A case study of optimizing machining parameters for multi-pass face milling operations is presented to verify the effectiveness of the proposed method.The case is to optimize parameters such as speed,feed,and depth of cut in each pass have yielded a minimum total product ion cost.The depth of cut of optimal strategy obtained by CICA are 4 mm,3 mm,1 mm for rough cutting pass 1,rough cutting pass 1 and finish cutting pass,respectively.The cost for each pass are$0.5366 US,$0.4473 US and$0.3738 US.The optimal solution of CICA for various strategies with at=8 mm is$1.3576 US.The results obtained with the proposed schemes are better than those of previous work.This shows the superior performance of CICA in solving such problems.Finally,optimization of cutting strategy when the width of workpiece no smaller than the diameter of cutter is discussed.Conclusion can be drawn that larger tool diameter and row spacing should be chosen to increase cutting efficiency.

The Research on Competitive Technology Alliance Innovation Risk Formation Mechanism: A Resource-based and Capability-based View

Enterprises engaging in collaboration with competitors can increase their technological diversity and release a new product innovation, but also full of challenges. This complexity of co-opetition relationship requirements academia and enterprises to clarify the problem of competitive technology alliance risk formation mechanism, making the risk control to dispose. Based on the perspective of resources and capabilities, this paper firstly puts forward the double helix model of alliances＇ evolution on resources and capabilities ; then, with the deepe- ning of the cooperation, this evolutionary process leads to different innovation risk： opportunism, R and D inte- gration risk and flexible loss risk; next, analyzing the corresponding management path and constructing the conceptual framework of risk management mechanism to help enterprise using the co-opetition relationship to reduce risk and improve the potential competitive advantage.

Competition vs cooperation:renewable energy investment under cap-and-trade mechanisms

This paper explores the incentives of investment in renewable energy of two utility firms who compete or cooperate under either a cap-and-trade grandfathering mechanism(GM)or benchmarking mechanism(BM).We find that utility firms will invest in renewable energy more under BM than under GM,in both competitive and cooperative markets,and they will invest more in a competitive market than in a cooperative market,under either GM or BM.Furthermore,utility firms will produce more electricity and generate more total carbon emissions under BM than under GM.The profits of two firms,however,are higher in cooperative market than in competitive market.The government will benefit from implementing a BM to encourage utility firms to invest in renewable energy in a competing market.

Competitive oxidation behavior of Ni-based superalloy GH4738 at extreme temperature

A high thrust-to-weight ratio poses challenges to the high-temperature performance of Ni-based superalloys. The oxidation behavior of GH4738 at extreme temperatures has been investigated by isothermal and non-isothermal experiments. As a result of the competitive diffusion of alloying elements, the oxide scale included an outermost porous oxide layer (OOL), an inner relatively dense oxide layer (IOL), and an internal oxide zone (IOZ), depending on the temperature and time. A high temperature led to the formation of large voids at the IOL/IOZ interface. At 1200℃, the continuity of the Cr-rich oxide layer in the IOL was destroyed, and thus, spallation occurred. Extension of oxidation time contributed to the size of Al-rich oxide particles with the increase in the IOZ. Based on this finding,the oxidation kinetics of GH4738 was discussed, and the corresponding oxidation behavior at 900-1100℃ was predicted.

Market-oriented management method of coalmine accident hidden dangers

By analyzing the problems which exist currently in the accident hidden dangers management of the coal mine, this paper proposed a new kind of management method--＂simulating the market＂, in which an operation pattern of simulating the market to transact hidden troubles was constructed. This method introduces ＂Market Mechanism＂ into safe management, and adopts measurable value to describe the hidden dangers such as＂ human behavior, technique, environment, equipments etc.＂. It regards the hidden dangers as ＂the goods produced by labor＂ which are found out by the safety managers and the security inspectors, then sells as ＂commodity＂. By the process of disposing, counterchecking, re-selling, and redisposing. It forms a set of market-oriented closed-form management pattern of coalmine accident hidden dangers. This kind of management method changes the past traditional methods in which the wageworkers treat safety management passively, but to encourage and restrict them to participate in the check-up and improvement of the hidden dangers.

Will Market-Oriented Reforms Propel Technology Progress?Empirical Evidence from China’s High-Tech Sectors

This paper aims to explore the effects of market-oriented reforms on industrial technology progress.Based on a theoretical analysis,we performed an empirical study with a marketization index and panel data of high-tech sectors in China.We found that market-oriented reforms had significantly propelled technology progress in China’s high-tech sectors,and the effects became more evident after China’s WTO entry.Market-oriented reforms induced technology progress by increasing capital allocation efficiency,R&D input,and technology diffusion.Among various aspects of market-oriented reforms,the institutional environment exerted the most significant effects,followed by the economy’s non-state sector,product market development,and factor market development;the government-market relationship index influenced technology’s progress the least.The effects are heterogeneous across sectors with different technology attributes and more significant for technology-intensive sectors.Our findings offer policy implications for China’s ongoing market-oriented reforms and policy design for technology progress in high-tech sectors.

Understanding Broad Polydispersity in Step-growth Polymerization via Catalyst Competition Mechanism

Conjugated polymers are mainly synthesized by cross-coupling polymerizations catalyzed with transition metal(Pd,Ni)catalysts through step-growth polymerization(SGP)mechanism.According to the classical theory of SGP,the polymer dispersion index(D)of the synthesized polymers will never be higher than 2.However,the cases where conjugated polymers synthesized with D value far exceeding 2 are very common in reality,which severely limits their processing property,performance and applications.To investigate the reason behind the D value deviation from the theoretical value of SGP,direct arylation polycondensation(DArP)of 2-bromo-3-hexylthiophene(3HT)was chosen as the model reaction,and the reaction process was tracked using gel permeation chromatography analysis.When Pd(OAc)_(2) was used as the catalyst,the D value linearly increased with the increase of the weight-average molecular weight(M_(w))of polymer(P3HT)after a short period and reached up to 7.2 at prolonged reaction time.Scanning transmission electron microscopic images of the reaction mixture showed the fibril-like aggregation of P3HT and assembling of Pd species in P3HT aggregates.A catalyst competition mechanism was thus proposed,together with numerical calculation,giving a good fitting to the experimental results,which is believed to have far-reaching significance for guiding the design,synthesis and processing of conjugated polymers.

Construction of CDKN2A-related competitive endogenous RNA network and identification of GAS5 as a prognostic indicator for hepatocellular carcinoma

BACKGROUND Competitive endogenous RNA(ceRNA)is an innovative way of gene expression modulation,which plays a crucial part in neoplasia.However,the intricacy and behavioral characteristics of the ceRNA network in hepatocellular carcinoma(HCC)remain dismal.AIM To establish a cyclin dependent kinase inhibitor 2A(CDKN2A)-related ceRNA network and recognize potential prognostic indicators for HCC.METHODS The mutation landscape of CDKN2A in HCC was first explored using the cBioPortal database.Differential expression analysis was implemented between CDKN2Ahigh and CDKN2Alow expression HCC samples.The targeted microRNAs were predicted by lncBasev3.0,and the targeted mRNAs were predicted by miRDB,and Targetscan database.The univariate and multivariate analysis were utilized to identify independent prognostic indicators.RESULTS CDKN2A was frequently mutated and deleted in HCC.The single-cell RNA-sequencing analysis revealed that CDKN2A participated in cell cycle pathways.The CDKN2A-related ceRNA network-growth arrest specific 5(GAS5)/miR-25-3p/SRY-box transcription factor 11(SOX11)was successfully established.GAS5 was recognized as an independent prognostic biomarker,whose overexpression was correlated with a poor prognosis in HCC patients.The association between GAS5 expression and methylation,immune infilt-ration was explored.Besides,traditional Chinese medicine effective components targeting GAS5 were obtained.CONCLUSION This CDKN2A-related ceRNA network provides innovative insights into the molecular mechanism of HCC formation and progression.Moreover,GAS5 might be a significant prognostic biomarker and therapeutic target in HCC.

揭榜挂帅制:一场科研组织模式的变革——基于新制度经济学的视角

目前揭榜挂帅制已得到广泛应用,成为我国突破关键核心技术的重要科研组织模式。本文基于新制度经济学的视角,构建制度环境、制度获利、制度创设的理论分析框架,考察由传统科研组织模式向揭榜挂帅制变迁的运行机理。基于动力的角度分析发现,揭榜挂帅制产生具有必然的逻辑:一方面国际科技竞争、新的科技革命以及高质量发展等新制度环境的变化是推动揭榜挂帅制产生的外在动力;另一方面科技发展战略的更新、规模经济的发挥、交易成本的节约等因素催生新的获利机会和潜在利润,成为驱使揭榜挂帅制产生的内在动力。基于演变轨迹的角度分析发现,揭榜挂帅制产生具有多重路径:一方面揭榜挂帅制兼具了内生性路径和外生性路径的统一过程,另一方面揭榜挂帅制也是强制性制度变迁和诱致性制度变迁的有机结合。

国家竞争情报真实场景的角色构成与群体智力集成机制研究——以美中经济与安全评估委员会听证会为例

[研究目的]基于实际事例开展国家竞争情报真实场景的角色构成与群体智力集成机制研究,为新时期新形势下的竞争情报工作创新发展提供参考。[研究方法]识别认定美中经济与安全评估委员会(U.S.-China Economic and Security Review Commission,USCC)听证会为国家竞争情报真实场景,系统收集整理USCC成立至今已经召开的171场听证会信息,基于听证会受邀参会者信息数据分析,以USCC听证会为例进行国家竞争情报真实场景的角色构成与群体智力集成机制研究。[研究结果/结论]研究发现国家竞争情报真实场景的角色构成包括国家竞争情报关键课题识别确定者、国家竞争情报组织生产者、国家竞争情报的直接用户群体,以及来自大学、智库、企业、政府部门、科研机构、社会团体、基金会、行业协会、律师事务所、新闻媒体等细分组织群体代表。以USCC听证会为例,研究归纳了国家竞争情报真实应用场景中的人际网络特点以及行之有效的群体智力集成机制关键点。

数字化转型赋能制造业新质生产力发展——基于资源基础理论与动态能力理论的实证研究

通过数字化转型引领新质生产力的发展,是数字经济赋能制造强国建设的重要课题。本文基于资源基础论与动态能力理论,剖析数字化转型驱动制造企业新质生产力发展的影响机理,为赋能新质生产力提供参考。结果发现:(1)数字化转型对制造企业新质生产力的长期与短期影响存在差异,短期表现为提升整合、配置及运用资源能力,长期表现为增强其创新变革的感知、抓取与转化能力;(2)实证结果表明,数字化转型对新质生产力的影响显著为正。其中,短期影响的正向作用显著,长期影响不显著。不仅如此,市场竞争强度的正向调节作用不容忽视;(3)根据异质性效应结果,东部地区影响显著为正,中部与西部地区则较为微弱;国有企业的驱动效应明显高于非国有企业样本。研究结论为提升制造业新质生产力水平提供了新的赋能方向。

基于“岗课赛证”融通的机械制造及自动化专业人才培养路径研究

基于“岗课赛证”融通理念,为机械制造及自动化专业优化构建人才培养路径,旨在提升学生的职业技能与岗位适应力。通过整合岗位需求、课程模块、职业证书和技能竞赛等要素,打造符合行业需求的课程体系。该研究通过分析岗位技能要求,定制课程内容,融入1+X证书标准,并引入校企协同育人机制,实现岗课赛证的有机衔接。通过此路径,提升学生的综合能力,满足企业对专业技能人才的需求,为高职教育的人才培养模式创新提供了有效参考。

Does Environmental Regulation Weaken Industrial Competitiveness?Inspirations from China’s Iron and Steel Sector

China＇s economic growth is heavily influenced by exports, while reconciling environmental regulation and economic growth requires handling the relationship between environmental regulation and industrial competitiveness well. The effects of environmental regulation on industrial competitiveness are largely subject to the institutional design of environmental regulation. Despite numerous studies on the relationship between environmental regulation and industrial competitiveness, a consensus has yet to be reached. Aside from differences in research methodology, these studies failed to give sufficient consideration to the impact of environmental regulation on industrial competitiveness. Such effects can be negative or positive depending on the design of environmental regulatory policy. This paper has investigated the relationship between environmental regulation and the competitiveness of China＇s iron and steel industry and discovered that tighter environmental regulation does not diminish the competitiveness of the iron and steel industry since the policy design of environmental regulation accommodates the tolerance of advanced production capacity and includes a reasonable cost sharing mechanism. This discovery is of important reference for China to develop rational policy design to balance the relationship between environmental regulation and industrial competitiveness.

科技成果赋权机制的创新与实践研究

为探讨科技成果赋权在实践研究和创新能力方面的实际应用及其重要性,从理论基础出发到实践探索分析了当前科技成果赋权面临的主要挑战和问题。通过案例分析和实证研究,探讨了科技成果赋权在不同领域和场景下的实际应用效果,提出完善科技成果的赋权机制,进一步激发科技创新的活力,推动经济社会持续健康发展。