BACKGROUND Association between tea consumption and incident hypertension remains uncertain.This study conducted to examine the health effects of tea consumption on blood pressure progression and hypertension incidence...BACKGROUND Association between tea consumption and incident hypertension remains uncertain.This study conducted to examine the health effects of tea consumption on blood pressure progression and hypertension incidence.METHODS A population-based cohort of 38,913 Chinese participants without hypertension at baseline were included in the current study.Information on tea consumption was collected through standardized questionnaires.Associations of tea consump-tion with blood pressure progression and incident hypertension were analyzed using logistic regression models and Cox propor-tional hazards regression models,respectively.RESULTS During a median follow-up of 5.9 years,17,657 individuals had experienced progression to a higher blood pressure stage and 5,935 individuals had developed hypertension.In multivariate analyses,habitual tea drinkers(≥3 times/week for at least six months)had a 17%lower risk for blood pressure progression[odds ratio(OR)=0.83,95%CI:0.79-0.88]and a 14%de-creased risk for incident hypertension[hazard ratio(HR)=0.86,95%CI:0.80-0.91]compared with non-habitual tea drinkers.In-dividuals in different baseline blood pressure groups could obtain similar benefit from habitual tea drinking.In terms of tea con-sumption amount,an inverse,linear dose-response relation between monthly consumption of tea leaves and risk of blood pres-sure progression was observed,while the risk of incident hypertension did not reduce further after consuming around 100 g of tea leaves per month.CONCLUSIONS Our study demonstrated that habitual tea consumption could provide preventive effect against blood pres-sure progression and hypertension incidence.展开更多
Diabetes and hypertension are common co-morbid associates and coexist in many of the cases. The study attempts to understand the two-way transition between diabetes and hypertension and the risk factors affecting the ...Diabetes and hypertension are common co-morbid associates and coexist in many of the cases. The study attempts to understand the two-way transition between diabetes and hypertension and the risk factors affecting the transition using the multistate model. The study used data from the first and second waves of IHDS. There is a significant rise in the level of diabetes and hypertension from 2004-05 to 2011-12. Except for transition from hypertension to diabetes, the probability of transition in all other transition decreases and the mean waiting time to stay in the healthy state increases after adjusting for several covariates. Increases in the level of smoking, drinking of alcohol, consumption of tobacco, body mass index, education and household income quintile are the major transition specific risk factors affecting the transition between diabetes and hypertension. And the risk of transitioning from a healthy state to hypertension is higher among females compared to males.展开更多
Objective:To compare the risk of target organ damage in masked hypertension(MH)and sustained hypertension(SH).Methods:A systematic review and meta-analysis was performed.A search of PubMed,Embase,and the Cochrane Libr...Objective:To compare the risk of target organ damage in masked hypertension(MH)and sustained hypertension(SH).Methods:A systematic review and meta-analysis was performed.A search of PubMed,Embase,and the Cochrane Library of relevant case-control studies was performed from inception to December 2019,and articles on MH and SH selected according to the inclusion criteria were analyzed.The primary end point was target organ damage in the heart.The secondary end points were target organ damage in the kidneys and blood vessels.Results:Seventeen studies that met the screening criteria were included in the meta-analysis.Compared with the SH group,in the MH group carotid intima-media thickness(IMT)and E/A ratio were signifi cantly greater and the prevalence of left ventricular remodeling and the pulse wave velocity were signifi cantly lower.Other indicators in the heart,kidneys,and blood vessels were not statistically different between the two groups.IMT:P=0.01,E/A ratio:P=0.01,prevalence of left ventricular remodeling:P=0.02,pulse wave velocity:P=0.01.Conclusion:Our study has shown that MH may have almost the same degree of target organ damage as SH,so clinicians may need to consider target organ damage.展开更多
The concept that hypertension is vascular inflammation has been widely recognized.A large number of experiments have been carried out in the past,but no relevant breakthroughs have been made in clinical application.At...The concept that hypertension is vascular inflammation has been widely recognized.A large number of experiments have been carried out in the past,but no relevant breakthroughs have been made in clinical application.At present,the drugs for clinical treatment of hypertension still take the previous pathogenesis of hypertension as the target,so the treatment of hypertension has not achieved satisfactory results.This article starts from the relationship between hypertension and inflammatory response,and integrates relevant research on the treatment of hypertension and inflammatory response by Chinese and Western medicine in the past three years,with a view to providing new directions and targets for the prevention and treatment of hypertension,so as to better control hypertension and Target organ damage.展开更多
Background Hypertension is the main risk factor for cardiovascular diseases, affecting more than half the elderly population. It is essential to know if they have proper control of hypertension. The aim of this study ...Background Hypertension is the main risk factor for cardiovascular diseases, affecting more than half the elderly population. It is essential to know if they have proper control of hypertension. The aim of this study was to identify the associated factors to masked uncon- trolled hypertension and false uncontrolled hypertension in older patients. Methods Two-hundred seventy-three individuals （70.1±6.7 years-old） had blood pressure （BP） measured at the office and by ambulatory BP monitoring （ABPM）, with the definition of controlled group （C）, individuals with high office BP and adequate ABPM, called white-coat effect group （WCE）, uncontrolled （UC）, and subjects with ap- propriate office BP and elevated ABPM denominated masked effect group （ME）. Age, body mass index, diabetes, pulse pressure （PP） and BP dipping during sleep were evaluated （Kruskal-Wallis test and logistic regression models）. Results Age was higher in UC than in C and ME （P 〈 0.01）, and 24-h ABPM PP was lower in C （48± 7 mmHg） and WCE （51±6 mmHg） than in UC （67±12 mmHg） and ME （59±8 mmHg） （P 〈 0.01）. Sleep systolic BP dipping was lower in ME than in C （P = 0.03）. Female gender was associated with a greater chance of being of ME group, which showed a higher PP and lower BP dipping during sleep. Conclusions In older individuals, office BP measure- ments did not allow the detection of associated factors that would permit to differentiate WCE from UC group and C from ME group. ABPM favored the identification of a higher PP and a lower BP dipping during sleep in the masked effect and uncontrolled groups.展开更多
Under Type-Ⅱ progressively hybrid censoring, this paper discusses statistical inference and optimal design on stepstress partially accelerated life test for hybrid system in presence of masked data. It is assumed tha...Under Type-Ⅱ progressively hybrid censoring, this paper discusses statistical inference and optimal design on stepstress partially accelerated life test for hybrid system in presence of masked data. It is assumed that the lifetime of the component in hybrid systems follows independent and identical modified Weibull distributions. The maximum likelihood estimations(MLEs)of the unknown parameters, acceleration factor and reliability indexes are derived by using the Newton-Raphson algorithm. The asymptotic variance-covariance matrix and the approximate confidence intervals are obtained based on normal approximation to the asymptotic distribution of MLEs of model parameters. Moreover,two bootstrap confidence intervals are constructed by using the parametric bootstrap method. The optimal time of changing stress levels is determined under D-optimality and A-optimality criteria.Finally, the Monte Carlo simulation study is carried out to illustrate the proposed procedures.展开更多
Background:An elderly was closed to some medical problem,especially hypertension.Problems that occur in elderly patients with hypertension not only involve the patient itself but also involve the family as the closest...Background:An elderly was closed to some medical problem,especially hypertension.Problems that occur in elderly patients with hypertension not only involve the patient itself but also involve the family as the closest person to the patient.One important aspect of family nursing is the family itself.To achieve good treatment outcomes,implementation of evidence-based nursing is needed.The purpose of this study is to present the implementation of evidence-based nursing to an eldelry in a family bu using coconut water to reduce high blood pressure and progressive muscle relaxation therapy to reduce pain intensity in hypertensive patients,as well as acupressure therapy in stopping smoking that is applied 1 week each other.Method:In the implementation,complementary therapy is applied to hypertensive patients by given young coconut water and progressive muscle relaxation therapy,and acupressure therapy in an effort to stop smoking.Results:showed significant results in the reduction of high blood pressure before being given an intervention was TD:200/100 mmHg and after being given the intervention obtained TD:140/80 mmHg and decreased pain intensity in hypertensive patients using relaxation therapy,as well as a decrease in the number of cigarettes smoked with acupressure therapy for 1 week.Conclusion:The application of complementary therapy carried out showed improvement in elderly patients suffering from hypertension and smoking behaviour,therefore,the application of evidence based nursing in providing nursing care is recommended.Suggestion:Complementary Nursing Case Study this is expended to be a reference material to improve health services and provide an overview in carrying out complementary nursing care to families,especially an elderly with comprehensive cases of hypertension(bio,psycho,social and spiritual).展开更多
基金the National Nature Science Foundation of China(No.91643208)the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(2017-I2M-1-004&2019-I2M-2-003)the National Key Research&Development Program of China(2017YFC0211700&2018YFE0115300)。
文摘BACKGROUND Association between tea consumption and incident hypertension remains uncertain.This study conducted to examine the health effects of tea consumption on blood pressure progression and hypertension incidence.METHODS A population-based cohort of 38,913 Chinese participants without hypertension at baseline were included in the current study.Information on tea consumption was collected through standardized questionnaires.Associations of tea consump-tion with blood pressure progression and incident hypertension were analyzed using logistic regression models and Cox propor-tional hazards regression models,respectively.RESULTS During a median follow-up of 5.9 years,17,657 individuals had experienced progression to a higher blood pressure stage and 5,935 individuals had developed hypertension.In multivariate analyses,habitual tea drinkers(≥3 times/week for at least six months)had a 17%lower risk for blood pressure progression[odds ratio(OR)=0.83,95%CI:0.79-0.88]and a 14%de-creased risk for incident hypertension[hazard ratio(HR)=0.86,95%CI:0.80-0.91]compared with non-habitual tea drinkers.In-dividuals in different baseline blood pressure groups could obtain similar benefit from habitual tea drinking.In terms of tea con-sumption amount,an inverse,linear dose-response relation between monthly consumption of tea leaves and risk of blood pres-sure progression was observed,while the risk of incident hypertension did not reduce further after consuming around 100 g of tea leaves per month.CONCLUSIONS Our study demonstrated that habitual tea consumption could provide preventive effect against blood pres-sure progression and hypertension incidence.
文摘Diabetes and hypertension are common co-morbid associates and coexist in many of the cases. The study attempts to understand the two-way transition between diabetes and hypertension and the risk factors affecting the transition using the multistate model. The study used data from the first and second waves of IHDS. There is a significant rise in the level of diabetes and hypertension from 2004-05 to 2011-12. Except for transition from hypertension to diabetes, the probability of transition in all other transition decreases and the mean waiting time to stay in the healthy state increases after adjusting for several covariates. Increases in the level of smoking, drinking of alcohol, consumption of tobacco, body mass index, education and household income quintile are the major transition specific risk factors affecting the transition between diabetes and hypertension. And the risk of transitioning from a healthy state to hypertension is higher among females compared to males.
文摘Objective:To compare the risk of target organ damage in masked hypertension(MH)and sustained hypertension(SH).Methods:A systematic review and meta-analysis was performed.A search of PubMed,Embase,and the Cochrane Library of relevant case-control studies was performed from inception to December 2019,and articles on MH and SH selected according to the inclusion criteria were analyzed.The primary end point was target organ damage in the heart.The secondary end points were target organ damage in the kidneys and blood vessels.Results:Seventeen studies that met the screening criteria were included in the meta-analysis.Compared with the SH group,in the MH group carotid intima-media thickness(IMT)and E/A ratio were signifi cantly greater and the prevalence of left ventricular remodeling and the pulse wave velocity were signifi cantly lower.Other indicators in the heart,kidneys,and blood vessels were not statistically different between the two groups.IMT:P=0.01,E/A ratio:P=0.01,prevalence of left ventricular remodeling:P=0.02,pulse wave velocity:P=0.01.Conclusion:Our study has shown that MH may have almost the same degree of target organ damage as SH,so clinicians may need to consider target organ damage.
基金Key R&D Program of Guangxi Science and Technology Department(No.AB17195054)Key R&D Program of Nanning Science and Technology Bureau(No.20173158-2)+3 种基金Guangxi First-Class Discipline Construction Project(No.2018XK070)Guangxi University Key Discipline Project(No.2017XJ03)Guangxi Medical and Health Key Discipline construction project(No.[2019]19)Guangxi University of Traditional Chinese Medicine Masters Innovation Project(No.YCSY2020105)。
文摘The concept that hypertension is vascular inflammation has been widely recognized.A large number of experiments have been carried out in the past,but no relevant breakthroughs have been made in clinical application.At present,the drugs for clinical treatment of hypertension still take the previous pathogenesis of hypertension as the target,so the treatment of hypertension has not achieved satisfactory results.This article starts from the relationship between hypertension and inflammatory response,and integrates relevant research on the treatment of hypertension and inflammatory response by Chinese and Western medicine in the past three years,with a view to providing new directions and targets for the prevention and treatment of hypertension,so as to better control hypertension and Target organ damage.
文摘Background Hypertension is the main risk factor for cardiovascular diseases, affecting more than half the elderly population. It is essential to know if they have proper control of hypertension. The aim of this study was to identify the associated factors to masked uncon- trolled hypertension and false uncontrolled hypertension in older patients. Methods Two-hundred seventy-three individuals （70.1±6.7 years-old） had blood pressure （BP） measured at the office and by ambulatory BP monitoring （ABPM）, with the definition of controlled group （C）, individuals with high office BP and adequate ABPM, called white-coat effect group （WCE）, uncontrolled （UC）, and subjects with ap- propriate office BP and elevated ABPM denominated masked effect group （ME）. Age, body mass index, diabetes, pulse pressure （PP） and BP dipping during sleep were evaluated （Kruskal-Wallis test and logistic regression models）. Results Age was higher in UC than in C and ME （P 〈 0.01）, and 24-h ABPM PP was lower in C （48± 7 mmHg） and WCE （51±6 mmHg） than in UC （67±12 mmHg） and ME （59±8 mmHg） （P 〈 0.01）. Sleep systolic BP dipping was lower in ME than in C （P = 0.03）. Female gender was associated with a greater chance of being of ME group, which showed a higher PP and lower BP dipping during sleep. Conclusions In older individuals, office BP measure- ments did not allow the detection of associated factors that would permit to differentiate WCE from UC group and C from ME group. ABPM favored the identification of a higher PP and a lower BP dipping during sleep in the masked effect and uncontrolled groups.
基金supported by the National Natural Science Foundation of China(71401134 71571144+1 种基金 71171164)the Program of International Cooperation and Exchanges in Science and Technology Funded by Shaanxi Province(2016KW-033)
文摘Under Type-Ⅱ progressively hybrid censoring, this paper discusses statistical inference and optimal design on stepstress partially accelerated life test for hybrid system in presence of masked data. It is assumed that the lifetime of the component in hybrid systems follows independent and identical modified Weibull distributions. The maximum likelihood estimations(MLEs)of the unknown parameters, acceleration factor and reliability indexes are derived by using the Newton-Raphson algorithm. The asymptotic variance-covariance matrix and the approximate confidence intervals are obtained based on normal approximation to the asymptotic distribution of MLEs of model parameters. Moreover,two bootstrap confidence intervals are constructed by using the parametric bootstrap method. The optimal time of changing stress levels is determined under D-optimality and A-optimality criteria.Finally, the Monte Carlo simulation study is carried out to illustrate the proposed procedures.
文摘Background:An elderly was closed to some medical problem,especially hypertension.Problems that occur in elderly patients with hypertension not only involve the patient itself but also involve the family as the closest person to the patient.One important aspect of family nursing is the family itself.To achieve good treatment outcomes,implementation of evidence-based nursing is needed.The purpose of this study is to present the implementation of evidence-based nursing to an eldelry in a family bu using coconut water to reduce high blood pressure and progressive muscle relaxation therapy to reduce pain intensity in hypertensive patients,as well as acupressure therapy in stopping smoking that is applied 1 week each other.Method:In the implementation,complementary therapy is applied to hypertensive patients by given young coconut water and progressive muscle relaxation therapy,and acupressure therapy in an effort to stop smoking.Results:showed significant results in the reduction of high blood pressure before being given an intervention was TD:200/100 mmHg and after being given the intervention obtained TD:140/80 mmHg and decreased pain intensity in hypertensive patients using relaxation therapy,as well as a decrease in the number of cigarettes smoked with acupressure therapy for 1 week.Conclusion:The application of complementary therapy carried out showed improvement in elderly patients suffering from hypertension and smoking behaviour,therefore,the application of evidence based nursing in providing nursing care is recommended.Suggestion:Complementary Nursing Case Study this is expended to be a reference material to improve health services and provide an overview in carrying out complementary nursing care to families,especially an elderly with comprehensive cases of hypertension(bio,psycho,social and spiritual).
