Multiparity amongst women with a body mass index (BMI) ≥ 30 Kg/m2 is a common occurrence despite there being a known clear association with a decline in fecundity in women who are overweight or obese. These women, al...Multiparity amongst women with a body mass index (BMI) ≥ 30 Kg/m2 is a common occurrence despite there being a known clear association with a decline in fecundity in women who are overweight or obese. These women, also pose further concerns, as they are at increased risk of antenatal complications such as preeclampsia and gestational diabetes. Over the years, a number of different modalities of fertility treatments have been tried and tested in this cohort of women to find the optimal treatment to improve their reproductive capacity. There has been an exponential increase in knowledge and understanding towards managing patients with a raised BMI, particularly through assisted reproductive treatments. Although the efficacies of various forms of fertility treatments have been shown to be affected by a rise in BMI, there is yet to be a definitive understanding as to the optimal management of these patients. The literature supports weight loss alone as an effective intervention in improving the reproductive capacity of women with a raised BMI with unexplained infertility. Furthermore, if live birth rate is taken as the desired outcome measure, then ovarian drilling and in vitro fertilisation (IVF) treatment have been shown to yield the best results in overweight and obese patients when comparisons are drawn to other interventions such as natural conception and treatment with clomiphene citrate.展开更多
The photosynthetic characteristics of flag leaf and the accumulation and remobilization of pre-anthesis dry mass(DM) and nitrogen(N) in vegetable organs in nine wheat cultivars under different source-sink manipula...The photosynthetic characteristics of flag leaf and the accumulation and remobilization of pre-anthesis dry mass(DM) and nitrogen(N) in vegetable organs in nine wheat cultivars under different source-sink manipulation treatments including defoliation(DF), spike shading(SS) and half spikelets removal(SR) were investigated. Results showed that the SS treatment increased the photosynthetic rate(Pn) of flag leaf in source limited cultivar, but had no significant effect on sink limited cultivar. The SR treatment decreased the Pn of flag leaf. Grain DM accumulation was limited by source in some cultivars, in other cultivars, it was limited by sink. Grain N accumulation was mainly limited by source supply. The contribution of pre-anthesis dry mass to grain yield from high to low was stem, leaf and chaff, while the contribution of pre-anthesis N to grain N from high to low was leaf, stem and chaff. Cultivars S7221 and TA9818 can increase the contribution of remobilization of DM and N to grain at the maximum ratio under reducing source treatments, which may be the major reason for these cultivars having lower decrease in grain yield and N content under reducing source treatments.展开更多
Rheumatoid Arthritis (RA) is an inflammatory disease associated with high morbidity and increased cardiovascular disease, and Metabolic Syndrome (MS) is understood as a set of metabolic disorders that correlates with ...Rheumatoid Arthritis (RA) is an inflammatory disease associated with high morbidity and increased cardiovascular disease, and Metabolic Syndrome (MS) is understood as a set of metabolic disorders that correlates with obesity and sedentary lifestyle. The aim of this study is to evaluate the prevalence of MS in a cohort of patients with RA and its correlation to specific factors of the disease. A retrospective cohort study was conducted with 283 patients with RA, followed at the Rheumatology Outpatient Clinic of the Hospital de Clínicas de Porto Alegre (HCPA) between 2008 and 2016;187 continued to be followed and agreed to be reevaluated between January and November 2016. MS was defined according to the National Cholesterol Education Program and disease activity was assessed using the Disease Activity Score (DAS28). Clinical, biochemical, and anthropometric evaluations were conducted. The prevalence of MS in the first evaluation was 43.9% and, after 8 years, 59.4%. Increased waist circumference and blood pressures, elevated triglycerides and low High-Density Lipoprotein were the most frequent features of MS. The DAS28 was significantly lower in the reevaluation (p = 0.006). The prevalence of MS was higher at the end of 8 years;disease activity, as well as blood pressure, decreased during this period. Steroid use had also decreased at the end of follow-up. There was an increase of 15% of cases with MS in an 8-year follow-up cohort of patients, which was in agreement with the current literature and showed how the inflammatory process in RA is correlated to MS. The parameters of MS that varied the most were blood pressure, cholesterol and triglycerides. Ultimately, these parameters and disease activity must be observed closely in order to improve the prognosis of patients with RA.展开更多
This study aims to consolidate the surface of gray cast iron with aluminum deposition by developing a method that combines the preparation and surface treatment in a single operation. The effect of the wall thickness ...This study aims to consolidate the surface of gray cast iron with aluminum deposition by developing a method that combines the preparation and surface treatment in a single operation. The effect of the wall thickness of the castings on the microstructure of the formed layers was studied, and two thicknesses, 8 mm and 25 mm, were studied. The formation of a continuous and homogeneous rich aluminum layer on the surface of the cast iron was observed. The formed layer is composed of two successive zones identified as two proeutectoid phases FeAl+FeAl/FeAl2 and single-phase FeAl, which significantly increases the surface hardness. Furthermore, this change in surface composition makes it possible to reduce the mass of the immersed samples in a 1 M hydrochloric acid solution during different exposure times(1 to 4 days). Consequently, a clear improvement in the corrosion resistance of the treated layers is highlighted.展开更多
文摘Multiparity amongst women with a body mass index (BMI) ≥ 30 Kg/m2 is a common occurrence despite there being a known clear association with a decline in fecundity in women who are overweight or obese. These women, also pose further concerns, as they are at increased risk of antenatal complications such as preeclampsia and gestational diabetes. Over the years, a number of different modalities of fertility treatments have been tried and tested in this cohort of women to find the optimal treatment to improve their reproductive capacity. There has been an exponential increase in knowledge and understanding towards managing patients with a raised BMI, particularly through assisted reproductive treatments. Although the efficacies of various forms of fertility treatments have been shown to be affected by a rise in BMI, there is yet to be a definitive understanding as to the optimal management of these patients. The literature supports weight loss alone as an effective intervention in improving the reproductive capacity of women with a raised BMI with unexplained infertility. Furthermore, if live birth rate is taken as the desired outcome measure, then ovarian drilling and in vitro fertilisation (IVF) treatment have been shown to yield the best results in overweight and obese patients when comparisons are drawn to other interventions such as natural conception and treatment with clomiphene citrate.
基金supported by the Special Fund for Agroscientific Research in the Public Interest in China (201303133, 201203031)the Key Technologies R&D Program of China during the 12th Five-Year Plan period (2011BAD16B14)+1 种基金the Construction of Modern Agricultural Industrial Technology System, Ministry of Agriculture, Chinathe Beijing Higher Education Young Elite Teacher Project, China (YETP0300)
文摘The photosynthetic characteristics of flag leaf and the accumulation and remobilization of pre-anthesis dry mass(DM) and nitrogen(N) in vegetable organs in nine wheat cultivars under different source-sink manipulation treatments including defoliation(DF), spike shading(SS) and half spikelets removal(SR) were investigated. Results showed that the SS treatment increased the photosynthetic rate(Pn) of flag leaf in source limited cultivar, but had no significant effect on sink limited cultivar. The SR treatment decreased the Pn of flag leaf. Grain DM accumulation was limited by source in some cultivars, in other cultivars, it was limited by sink. Grain N accumulation was mainly limited by source supply. The contribution of pre-anthesis dry mass to grain yield from high to low was stem, leaf and chaff, while the contribution of pre-anthesis N to grain N from high to low was leaf, stem and chaff. Cultivars S7221 and TA9818 can increase the contribution of remobilization of DM and N to grain at the maximum ratio under reducing source treatments, which may be the major reason for these cultivars having lower decrease in grain yield and N content under reducing source treatments.
文摘Rheumatoid Arthritis (RA) is an inflammatory disease associated with high morbidity and increased cardiovascular disease, and Metabolic Syndrome (MS) is understood as a set of metabolic disorders that correlates with obesity and sedentary lifestyle. The aim of this study is to evaluate the prevalence of MS in a cohort of patients with RA and its correlation to specific factors of the disease. A retrospective cohort study was conducted with 283 patients with RA, followed at the Rheumatology Outpatient Clinic of the Hospital de Clínicas de Porto Alegre (HCPA) between 2008 and 2016;187 continued to be followed and agreed to be reevaluated between January and November 2016. MS was defined according to the National Cholesterol Education Program and disease activity was assessed using the Disease Activity Score (DAS28). Clinical, biochemical, and anthropometric evaluations were conducted. The prevalence of MS in the first evaluation was 43.9% and, after 8 years, 59.4%. Increased waist circumference and blood pressures, elevated triglycerides and low High-Density Lipoprotein were the most frequent features of MS. The DAS28 was significantly lower in the reevaluation (p = 0.006). The prevalence of MS was higher at the end of 8 years;disease activity, as well as blood pressure, decreased during this period. Steroid use had also decreased at the end of follow-up. There was an increase of 15% of cases with MS in an 8-year follow-up cohort of patients, which was in agreement with the current literature and showed how the inflammatory process in RA is correlated to MS. The parameters of MS that varied the most were blood pressure, cholesterol and triglycerides. Ultimately, these parameters and disease activity must be observed closely in order to improve the prognosis of patients with RA.
文摘This study aims to consolidate the surface of gray cast iron with aluminum deposition by developing a method that combines the preparation and surface treatment in a single operation. The effect of the wall thickness of the castings on the microstructure of the formed layers was studied, and two thicknesses, 8 mm and 25 mm, were studied. The formation of a continuous and homogeneous rich aluminum layer on the surface of the cast iron was observed. The formed layer is composed of two successive zones identified as two proeutectoid phases FeAl+FeAl/FeAl2 and single-phase FeAl, which significantly increases the surface hardness. Furthermore, this change in surface composition makes it possible to reduce the mass of the immersed samples in a 1 M hydrochloric acid solution during different exposure times(1 to 4 days). Consequently, a clear improvement in the corrosion resistance of the treated layers is highlighted.