A 10 J, 4o us XeCl laser interaction with LY12 aluminum and optical glass K9 targets is reported. The properties of laser-produced plasma (LPP) are analyzed. As a result, some parameters such as plasma ignition thresh...A 10 J, 4o us XeCl laser interaction with LY12 aluminum and optical glass K9 targets is reported. The properties of laser-produced plasma (LPP) are analyzed. As a result, some parameters such as plasma ignition threshold and plasma plume expansion velocity are obtained. Also, Laser induced pulse on irradiated targets are given.展开更多
A thermodynamic model has been built up for the interactions between molten Ti alloys and oxide molding materials in the way of decomposition and solution of molding materials, then the influences on the reaction free...A thermodynamic model has been built up for the interactions between molten Ti alloys and oxide molding materials in the way of decomposition and solution of molding materials, then the influences on the reaction free energy changes have been calculated and discussed.展开更多
The 1st International Conference on the Material Point Method for ＂Modelling Large Deformation and Soil–Water–Structure Interaction＂（MPM2017）was held in Delft,The Netherlands on 10-13 January 2017.This is the fi...The 1st International Conference on the Material Point Method for ＂Modelling Large Deformation and Soil–Water–Structure Interaction＂（MPM2017）was held in Delft,The Netherlands on 10-13 January 2017.This is the first conference organised by the Anura3D MPM Research Community,following a series of international workshops and symposia previously held in The Netherlands,UK,Spain and Italy,as part of the European Commission FP7 Marie-Curie project MPM-DREDGE.We are delighted to present seven contributions in this Special Column of the Journal of Hydrodynamics,and take this opportunity to announce that the 2nd conference,MPM2019,will be held in Cambridge,UK in January 2019.展开更多
Objectives We are delighted to invite you to join us at the second Intemational Conference on the Material Point Method for Modelling Soil-Water-Structure Interaction organised by the Anura3D MPM Research Community （...Objectives We are delighted to invite you to join us at the second Intemational Conference on the Material Point Method for Modelling Soil-Water-Structure Interaction organised by the Anura3D MPM Research Community （www.Anura3D.com） in January 2019 in Cambridge （MPM2019）. This is the second interna- tional conference organised by the Community, following a series of workshops and symposia, sponsored by the FP7 Marie-Curie project MPM-DREDGE, and the success of MPM2017 held in Delft in January 2017.展开更多
Objectives We are delighted to invite you to join us at the second International Conference on the Material Point Method for Modelling Soil-Water-Structure Interaction organised by the Anura3D MPM Research Community ...Objectives We are delighted to invite you to join us at the second International Conference on the Material Point Method for Modelling Soil-Water-Structure Interaction organised by the Anura3D MPM Research Community （www.Anura3D.com） in January 2019 in Cambridge （MPM2019）. This is the second international conference organised by the Community, following a series of workshops and symposia, sponsored by the FP7 Marie-Curie project MPM-DREDGE, and the success of MPM2017 held in Delft in January 2017.展开更多
8-11 January 2019,Cambridge,UK Objectives We are delighted to invite you to join us at the second International Conference on the Material Point Method for Modelling Soil-Water-Structure Interaction organised by the A...8-11 January 2019,Cambridge,UK Objectives We are delighted to invite you to join us at the second International Conference on the Material Point Method for Modelling Soil-Water-Structure Interaction organised by the Anura3D MPM Research Community（www.Anura3D.com）in January 2019 in Cambridge（MPM2019）.展开更多
Recent cumulative findings signify the adaptive immunity of materials as a key agenda in tissue healing that can improve regenerative events and outcomes. Modulating immune responses, mainly the recruitment and functi...Recent cumulative findings signify the adaptive immunity of materials as a key agenda in tissue healing that can improve regenerative events and outcomes. Modulating immune responses, mainly the recruitment and functions of T and B cells and their further interplay with innate immune cells (e.g., dendritic cells, macrophages) can be orchestrated by materials. For instance, decellularized matrices have been shown to promote muscle healing by inducing T helper 2 (Th2) cell immunity, while synthetic biopolymers exhibit differential effects on B cell responses and fibrosis compared decellularized matrices. We discuss the recent findings on how implantable materials instruct the adaptive immune events and the subsequent tissue healing process. In particular, we dissect the materials’ physicochemical properties (shape, size, topology, degradation, rigidity, and matrix dynamic mechanics) to demonstrate the relations of these parameters with the adaptive immune responses in vitro and the underlying biological mechanisms. Furthermore, we present evidence of recent in vivo phenomena, including tissue healing, cancer progression, and fibrosis, wherein biomaterials potentially shape adaptive immune cell functions and in vivo outcomes. Our discussion will help understand the materials-regulated immunology events more deeply, and offer the design rationale of materials with tunable matrix properties for accelerated tissue repair and regeneration.展开更多
How to register and submit contributions： Authors are invited to submit their contributions on any of the conference topics. Submissions and conference registration can only be performed via the conference website：...How to register and submit contributions： Authors are invited to submit their contributions on any of the conference topics. Submissions and conference registration can only be performed via the conference website： http：//www.mpm2017.eu展开更多
Due to the innate extracellular matrix mimicking features,fibrous materials exhibited great application potential in biomedicine.In developing excellent fibrous biomaterial,it is essential to reveal the corresponding ...Due to the innate extracellular matrix mimicking features,fibrous materials exhibited great application potential in biomedicine.In developing excellent fibrous biomaterial,it is essential to reveal the corresponding inherent fiber features’effects on cell behaviors.Due to the inevitable‘interference’cell adhesions to the background or between adjacent fibers,it is difficult to precisely reveal the inherent fiber diameter effect on cell behaviors by using a traditional fiber mat.A single-layer and parallel-arranged polycaprolactone fiber pattern platform with an excellent non-fouling background is designed and constructed herein.In this unique material platform,the‘interference’cell adhesions through interspace between fibers to the environment could be effectively ruled out by the non-fouling background.The‘interference’cell adhesions between adjacent fibers could also be excluded from the sparsely arranged(SA)fiber patterns.The influence of fiber diameter on stem cell behaviors is precisely and comprehensively investigated based on eliminating the undesired‘interference’cell adhesions in a controllable way.On the SA fiber patterns,small diameter fiber(SA-D1,D1 means 1μm in diameter)may seriously restrict cell proliferation and osteogenesis when compared to the middle(SA-D8)and large(SA-D56)ones and SA-D8 shows the optimal osteogenesis enhancement effect.At the same time,the cells present similar proliferation ability and even the highest osteogenic ability on the densely arranged(DA)fiber patterns with small diameter fiber(DA-D1)when compared to the middle(DA-D8)and large(DA-D56)ones.The‘interference’cell adhesion between adjacent fibers under dense fiber arrangement may be the main reason for inducing these different cell behavior trends along with fiber diameters.Related results and comparisons have illustrated the effects of fiber diameter on stem cell behaviors more precisely and objectively,thus providing valuable reference and guidance for developing effective fibrous biomaterials.展开更多
Cell–material interactions during early osseointegration of the bone–implant interface are critical and involve crosstalk between osteoblasts and osteoclasts.The surface properties of titanium implants also play a c...Cell–material interactions during early osseointegration of the bone–implant interface are critical and involve crosstalk between osteoblasts and osteoclasts.The surface properties of titanium implants also play a critical role in cell–material interactions.In this study,femtosecond laser treatment and sandblasting were used to alter the surface morphology,roughness and wettability of a titanium alloy.Osteoblasts and osteoclasts were then cultured on the resulting titanium alloy disks.Four disk groups were tested:a polished titanium alloy(pTi)control;a hydrophilic micro-dislocation titanium alloy(sandblasted Ti(STi));a hydrophobic nano-mastoid Ti alloy(femtosecond laser-treated Ti(FTi));and a hydrophilic hierarchical hybrid micro-/nanostructured Ti alloy[femtosecond laser-treated and sandblasted Ti(FSTi)].The titanium surface treated by the femtosecond laser and sandblasting showed higher biomineralization activity and lower cytotoxicity in simulated body fluid and lactate dehydrogenase assays.Compared to the control surface,the multifunctional titanium surface induced a better cellular response in terms of proliferation,differentiation,mineralization and collagen secretion.Further investigation of macrophage polarization revealed that increased anti-inflammatory factor secretion and decreased proinflammatory factor secretion occurred in the early response of macrophages.Based on the above results,the synergistic effect of the surface properties produced an excellent cellular response at the bone–implant interface,which was mainly reflected by the promotion of early ossteointegration andmacrophage polarization.展开更多
文摘A 10 J, 4o us XeCl laser interaction with LY12 aluminum and optical glass K9 targets is reported. The properties of laser-produced plasma (LPP) are analyzed. As a result, some parameters such as plasma ignition threshold and plasma plume expansion velocity are obtained. Also, Laser induced pulse on irradiated targets are given.
基金This work was supported by Postdoctoral Foundation of Northwestern Polytechnical University and Science Research FOundation o
文摘A thermodynamic model has been built up for the interactions between molten Ti alloys and oxide molding materials in the way of decomposition and solution of molding materials, then the influences on the reaction free energy changes have been calculated and discussed.
基金support provided by the European Union Seventh Framework Program(FP7/2007-2013)under grant agreement No.PIAG-GA-2012-324522“MPM-DREDGE”
文摘The 1st International Conference on the Material Point Method for ＂Modelling Large Deformation and Soil–Water–Structure Interaction＂（MPM2017）was held in Delft,The Netherlands on 10-13 January 2017.This is the first conference organised by the Anura3D MPM Research Community,following a series of international workshops and symposia previously held in The Netherlands,UK,Spain and Italy,as part of the European Commission FP7 Marie-Curie project MPM-DREDGE.We are delighted to present seven contributions in this Special Column of the Journal of Hydrodynamics,and take this opportunity to announce that the 2nd conference,MPM2019,will be held in Cambridge,UK in January 2019.
文摘Objectives We are delighted to invite you to join us at the second Intemational Conference on the Material Point Method for Modelling Soil-Water-Structure Interaction organised by the Anura3D MPM Research Community （www.Anura3D.com） in January 2019 in Cambridge （MPM2019）. This is the second interna- tional conference organised by the Community, following a series of workshops and symposia, sponsored by the FP7 Marie-Curie project MPM-DREDGE, and the success of MPM2017 held in Delft in January 2017.
文摘Objectives We are delighted to invite you to join us at the second International Conference on the Material Point Method for Modelling Soil-Water-Structure Interaction organised by the Anura3D MPM Research Community （www.Anura3D.com） in January 2019 in Cambridge （MPM2019）. This is the second international conference organised by the Community, following a series of workshops and symposia, sponsored by the FP7 Marie-Curie project MPM-DREDGE, and the success of MPM2017 held in Delft in January 2017.
文摘8-11 January 2019,Cambridge,UK Objectives We are delighted to invite you to join us at the second International Conference on the Material Point Method for Modelling Soil-Water-Structure Interaction organised by the Anura3D MPM Research Community（www.Anura3D.com）in January 2019 in Cambridge（MPM2019）.
基金National Research Foundation of Korea(NRF,2021R1A5A2022318,2019R1A6A1A11034536,RS-2023-00220408,RS-2024-00334160,RS-2024-00348908)Ministry of Science and ICT and Ministry of Education.
文摘Recent cumulative findings signify the adaptive immunity of materials as a key agenda in tissue healing that can improve regenerative events and outcomes. Modulating immune responses, mainly the recruitment and functions of T and B cells and their further interplay with innate immune cells (e.g., dendritic cells, macrophages) can be orchestrated by materials. For instance, decellularized matrices have been shown to promote muscle healing by inducing T helper 2 (Th2) cell immunity, while synthetic biopolymers exhibit differential effects on B cell responses and fibrosis compared decellularized matrices. We discuss the recent findings on how implantable materials instruct the adaptive immune events and the subsequent tissue healing process. In particular, we dissect the materials’ physicochemical properties (shape, size, topology, degradation, rigidity, and matrix dynamic mechanics) to demonstrate the relations of these parameters with the adaptive immune responses in vitro and the underlying biological mechanisms. Furthermore, we present evidence of recent in vivo phenomena, including tissue healing, cancer progression, and fibrosis, wherein biomaterials potentially shape adaptive immune cell functions and in vivo outcomes. Our discussion will help understand the materials-regulated immunology events more deeply, and offer the design rationale of materials with tunable matrix properties for accelerated tissue repair and regeneration.
文摘How to register and submit contributions： Authors are invited to submit their contributions on any of the conference topics. Submissions and conference registration can only be performed via the conference website： http：//www.mpm2017.eu
基金sponsored by the Natural Science Foundation of Shanghai(20ZR1402400)the Fundamental Research Funds for the Central Universities(2232020D-04)+2 种基金the National Natural Science Foundation of China(52273125,52173031 and 51903045)the Science and Technology Commission of Shanghai Municipality(20XD1400100,22520711900 and 21JC1400100)the Fundamental Research Funds for the Central Universities(2232019A3-06 and 2232019D3-02).
文摘Due to the innate extracellular matrix mimicking features,fibrous materials exhibited great application potential in biomedicine.In developing excellent fibrous biomaterial,it is essential to reveal the corresponding inherent fiber features’effects on cell behaviors.Due to the inevitable‘interference’cell adhesions to the background or between adjacent fibers,it is difficult to precisely reveal the inherent fiber diameter effect on cell behaviors by using a traditional fiber mat.A single-layer and parallel-arranged polycaprolactone fiber pattern platform with an excellent non-fouling background is designed and constructed herein.In this unique material platform,the‘interference’cell adhesions through interspace between fibers to the environment could be effectively ruled out by the non-fouling background.The‘interference’cell adhesions between adjacent fibers could also be excluded from the sparsely arranged(SA)fiber patterns.The influence of fiber diameter on stem cell behaviors is precisely and comprehensively investigated based on eliminating the undesired‘interference’cell adhesions in a controllable way.On the SA fiber patterns,small diameter fiber(SA-D1,D1 means 1μm in diameter)may seriously restrict cell proliferation and osteogenesis when compared to the middle(SA-D8)and large(SA-D56)ones and SA-D8 shows the optimal osteogenesis enhancement effect.At the same time,the cells present similar proliferation ability and even the highest osteogenic ability on the densely arranged(DA)fiber patterns with small diameter fiber(DA-D1)when compared to the middle(DA-D8)and large(DA-D56)ones.The‘interference’cell adhesion between adjacent fibers under dense fiber arrangement may be the main reason for inducing these different cell behavior trends along with fiber diameters.Related results and comparisons have illustrated the effects of fiber diameter on stem cell behaviors more precisely and objectively,thus providing valuable reference and guidance for developing effective fibrous biomaterials.
基金The authors acknowledge financial support from the National Natural Science Foundation of China(11972198,31470935 and 11432016).
文摘Cell–material interactions during early osseointegration of the bone–implant interface are critical and involve crosstalk between osteoblasts and osteoclasts.The surface properties of titanium implants also play a critical role in cell–material interactions.In this study,femtosecond laser treatment and sandblasting were used to alter the surface morphology,roughness and wettability of a titanium alloy.Osteoblasts and osteoclasts were then cultured on the resulting titanium alloy disks.Four disk groups were tested:a polished titanium alloy(pTi)control;a hydrophilic micro-dislocation titanium alloy(sandblasted Ti(STi));a hydrophobic nano-mastoid Ti alloy(femtosecond laser-treated Ti(FTi));and a hydrophilic hierarchical hybrid micro-/nanostructured Ti alloy[femtosecond laser-treated and sandblasted Ti(FSTi)].The titanium surface treated by the femtosecond laser and sandblasting showed higher biomineralization activity and lower cytotoxicity in simulated body fluid and lactate dehydrogenase assays.Compared to the control surface,the multifunctional titanium surface induced a better cellular response in terms of proliferation,differentiation,mineralization and collagen secretion.Further investigation of macrophage polarization revealed that increased anti-inflammatory factor secretion and decreased proinflammatory factor secretion occurred in the early response of macrophages.Based on the above results,the synergistic effect of the surface properties produced an excellent cellular response at the bone–implant interface,which was mainly reflected by the promotion of early ossteointegration andmacrophage polarization.
