In the context of applying computer aided design tools to aircraft conceptualdesign, a sketch based approach is proposed to help designers turn their original concepts intocomplex numerical models that are usable for ...In the context of applying computer aided design tools to aircraft conceptualdesign, a sketch based approach is proposed to help designers turn their original concepts intocomplex numerical models that are usable for further analysis and optimization. This approachemphasizes the integration of general configuration and the layout of such components as engines,payloads, fuel tanks and landing gears, and the representation of a design scheme as uniform planesketches and three dimensional models. This paper presents the measures adopted to implement theapproach in a prototype system, including the object-oriented data structure, friendly graphicaluser interfaces and basic features of relevant modules. Several examples generated in the prototypeand applications of the results are finally outlined to illustrate the effectiveness of theapproach.展开更多
To get an optimal product of orthopaedic implant or regenerative medicine needs to follow trialand-error analyses to investigate suitable product’s material,structure,mechanical properites etc.The whole process from ...To get an optimal product of orthopaedic implant or regenerative medicine needs to follow trialand-error analyses to investigate suitable product’s material,structure,mechanical properites etc.The whole process from in vivo tests to clinical trials is expensive and time-consuming.Computational model is seen as a useful analysis tool to make the product development.A series of models for simulating tissue engineering process from cell attachment to tissue regeneration are reviewed.The challenging is that models for simulating tissue engineering processes are developed separately.From cell to tissue regeneration,it would go through blood injection after moving out the defect;to cell disperse and attach on the scaffold;to proliferation,migration and differentiation;and to the final part-becoming mature tissues.This paper reviewed models that related to tissue engineering process,aiming to provide an opportunity for researchers to develop a mature model for whole tissue engineering process.This article focuses on the model analysis methods of cell adhesion,nutrient transport and cell proliferation,differentiation and migration in tissue engineering.In cell adhesion model,one of the most accurate method is to use discrete phase model to govern cell movement and use Stanton-Rutland model for simulating cell attachment.As for nutrient transport model,numerical model coupling with volume of fluid model and species transport model together is suitable for predicting nutrient transport process.For cell proliferation,differentiation and migration,finite element method with random-walk algorithm is one the most advanced way to simulate these processes.Most of the model analysis methods require further experiments to verify the accuracy and effectiveness.Due to the lack of technology to detect the rate of nutrient diffusion,there are especially few researches on model analysis methods in the area of blood coagulation.Therefore,there is still a lot of work to be done in the research of the whole process model method of tissue engineering.In the future,the numerical model would be seen as an optimal way to investigate tissue engineering products bioperformance and also enable to optimize the parameters and material types of the tissue engineering products.展开更多
针对部分机电产品在概念设计阶段未综合考虑客户和环境的需求,进而影响产品详细设计的问题,提出了一种基于功能—结构—客户和环境需求(function‒structure‒requirements of customer and environment,FSRce)模型的机电产品绿色概念设...针对部分机电产品在概念设计阶段未综合考虑客户和环境的需求,进而影响产品详细设计的问题,提出了一种基于功能—结构—客户和环境需求(function‒structure‒requirements of customer and environment,FSRce)模型的机电产品绿色概念设计方案生成方法。首先,从案例库中选择合适的功能和结构对现有产品设计树中的节点进行扩展和关联;同时通过数据挖掘、专家打分等方法获得产品的客户和环境需求重要度,以构建基于FSRce模型的产品概念设计空间。然后,先利用加权区间粗糙数法对客户和环境需求重要度进行分析,得到需求相对重要度,再运用模糊质量功能展开(fuzzy quality function deployment,FQFD)将需求相对重要度转化为产品的工程特性权重。最后,利用物元理论构建基于工程特性的产品物元域和各结构物元集,并结合工程特性权重得到各结构的满意度分值,通过比较满意度优选得到满足客户和环境需求的产品概念设计方案。以某小型工业吹风机为例,基于上述方法对其概念设计方案进行优化。相比于原始方案,优化后的吹风机在能源消耗上降低了15.38%,在碳排放上降低了15.32%,且客户满意度提高了44.66%,由此验证了所提出方法的可行性与有效性。所提出的方法为机电产品概念设计方案的生成提供了一种新思路,能更好地辅助设计人员实现对机电产品的绿色设计。展开更多
文摘In the context of applying computer aided design tools to aircraft conceptualdesign, a sketch based approach is proposed to help designers turn their original concepts intocomplex numerical models that are usable for further analysis and optimization. This approachemphasizes the integration of general configuration and the layout of such components as engines,payloads, fuel tanks and landing gears, and the representation of a design scheme as uniform planesketches and three dimensional models. This paper presents the measures adopted to implement theapproach in a prototype system, including the object-oriented data structure, friendly graphicaluser interfaces and basic features of relevant modules. Several examples generated in the prototypeand applications of the results are finally outlined to illustrate the effectiveness of theapproach.
基金supported by the Versus Arthritis Research UK(Grant No:21977)European Commission via a H2020-MSCA-RISE programme(BAMOS,Grant No:734156)+1 种基金Innovative UK via Newton Fund(Grant No:102872)Engineering and Physical Science Research Council(EPSRC)via DTP CASE programme(Grant No:EP/T517793/1)。
文摘To get an optimal product of orthopaedic implant or regenerative medicine needs to follow trialand-error analyses to investigate suitable product’s material,structure,mechanical properites etc.The whole process from in vivo tests to clinical trials is expensive and time-consuming.Computational model is seen as a useful analysis tool to make the product development.A series of models for simulating tissue engineering process from cell attachment to tissue regeneration are reviewed.The challenging is that models for simulating tissue engineering processes are developed separately.From cell to tissue regeneration,it would go through blood injection after moving out the defect;to cell disperse and attach on the scaffold;to proliferation,migration and differentiation;and to the final part-becoming mature tissues.This paper reviewed models that related to tissue engineering process,aiming to provide an opportunity for researchers to develop a mature model for whole tissue engineering process.This article focuses on the model analysis methods of cell adhesion,nutrient transport and cell proliferation,differentiation and migration in tissue engineering.In cell adhesion model,one of the most accurate method is to use discrete phase model to govern cell movement and use Stanton-Rutland model for simulating cell attachment.As for nutrient transport model,numerical model coupling with volume of fluid model and species transport model together is suitable for predicting nutrient transport process.For cell proliferation,differentiation and migration,finite element method with random-walk algorithm is one the most advanced way to simulate these processes.Most of the model analysis methods require further experiments to verify the accuracy and effectiveness.Due to the lack of technology to detect the rate of nutrient diffusion,there are especially few researches on model analysis methods in the area of blood coagulation.Therefore,there is still a lot of work to be done in the research of the whole process model method of tissue engineering.In the future,the numerical model would be seen as an optimal way to investigate tissue engineering products bioperformance and also enable to optimize the parameters and material types of the tissue engineering products.
文摘针对部分机电产品在概念设计阶段未综合考虑客户和环境的需求,进而影响产品详细设计的问题,提出了一种基于功能—结构—客户和环境需求(function‒structure‒requirements of customer and environment,FSRce)模型的机电产品绿色概念设计方案生成方法。首先,从案例库中选择合适的功能和结构对现有产品设计树中的节点进行扩展和关联;同时通过数据挖掘、专家打分等方法获得产品的客户和环境需求重要度,以构建基于FSRce模型的产品概念设计空间。然后,先利用加权区间粗糙数法对客户和环境需求重要度进行分析,得到需求相对重要度,再运用模糊质量功能展开(fuzzy quality function deployment,FQFD)将需求相对重要度转化为产品的工程特性权重。最后,利用物元理论构建基于工程特性的产品物元域和各结构物元集,并结合工程特性权重得到各结构的满意度分值,通过比较满意度优选得到满足客户和环境需求的产品概念设计方案。以某小型工业吹风机为例,基于上述方法对其概念设计方案进行优化。相比于原始方案,优化后的吹风机在能源消耗上降低了15.38%,在碳排放上降低了15.32%,且客户满意度提高了44.66%,由此验证了所提出方法的可行性与有效性。所提出的方法为机电产品概念设计方案的生成提供了一种新思路,能更好地辅助设计人员实现对机电产品的绿色设计。
