Objective To establish and evaluate a protein serum ferritin (SF) and soluble transferrin receptor microarray method for combined measurement of (sTfR). Methods Microarrayer was used to print both anti-SF antibodi...Objective To establish and evaluate a protein serum ferritin (SF) and soluble transferrin receptor microarray method for combined measurement of (sTfR). Methods Microarrayer was used to print both anti-SF antibodies I and anti-sTfR antibodies I on each protein microarray. Anti-SF antibodies II and anti-sTfR antibodies II were used as detection antibodies and goat antibodies coupled to Cy3 were used as antibodies Ill. The detection conditions of the quantitative analysis method for simultaneous measurement of SF and sTfR with protein microarray were optimized and evaluated. The protein microarray was compared with commercially available traditional tests with 26 serum samples. Results By comparison experiment, mouse monoclonal antibodies were chosen as the probes and contact printing was chosen as the printing method. The concentrations of SF and sTfR probes were 0.5 mg/mL and 0.5 mg/mL respectively, while those of SF and sTfR detection antibodies were 5 μg/mL and 0.36 μg/mL respectively. Intra- and inter-assay variability was between 3.26% and 18.38% for all tests. The regression coefficients comparing protein microarray with traditional test assays were better than 0.81 for SF and sTfR. Conclusion The present study has established a protein microarray method for combined measurement of SF and sTfR.展开更多
This paper concerns the construction and regularity of a transition (probability) function of a nonhomogeneous continuous-time Maxkov process with given transition rates and a general state space. Motivating from a ...This paper concerns the construction and regularity of a transition (probability) function of a nonhomogeneous continuous-time Maxkov process with given transition rates and a general state space. Motivating from a lot of restriction in applications of a transition function with continuous (in t ≥0) and consewative transition rates q(t, x, A), we consider the case that q(t, x, A) axe only required to satisfy a mild measurability (in t ≥ O) condition, which is a generalization of the continuity condition. Under the measurability condition we construct a transition function with the given transition rates, provide a necessary and sufficient condition for it to be regular, and further obtain some interesting additional results.展开更多
The real-world fuel efficiency and exhaust emission profiles of CO, HC and NOx for light-duty diesel vehicles were investigated. Using a portable emissions measurement system, 16 diesel taxies were tested on different...The real-world fuel efficiency and exhaust emission profiles of CO, HC and NOx for light-duty diesel vehicles were investigated. Using a portable emissions measurement system, 16 diesel taxies were tested on different roads in Macao and the data were normalized with the vehicle specific power bin method. The 11 Toyota Corolla diesel taxies have very good fuel economy of (5.9 ± 0.6) L/100 km, while other five diesel taxies showed relatively high values at (8.5 ± 1.7) L/100 km due to the variation in transmission systems and emission control strategies. Compared to similar Corolla gasoline models, the diesel cars confirmed an advantage of ca. 20% higher fuel efficiency. HC and CO emissions of all the 16 taxies are quite low, with the average at (0.05 ± 0.02) g/km and (0.38 ± 0.15) g/km, respectively. The average NOx emission factor of the 11 Corolla taxies is (0.56 ± 0.17) g/km, about three times higher than their gasoline counterparts. Two of the three Hyundai Sonata taxies, configured with exhaust gas recirculation (EGR) + diesel oxidation catalyst (DOC) emission control strategies, indicated significantly higher NO2 emissions and NO2/NOx ratios than other diesel taxies and consequently trigger a concern of possibly adverse impacts on ozone pollution in urban areas with this technology combination. A clear and similar pattern for fuel consumption and for each of the three gaseous pollutant emissions with various road conditions was identified. To save energy and mitigate CO2 emissions as well as other gaseous pollutant emissions in urban area, traffic planning also needs improvement.展开更多
This paper introduces and represents conditional coherent risk measures as essential suprema of conditional expectations over a convex set of probability measures and as distorted expectations given a concave distorti...This paper introduces and represents conditional coherent risk measures as essential suprema of conditional expectations over a convex set of probability measures and as distorted expectations given a concave distortion function.A model is then developed for the bid and ask prices of a European-type asset by a conic formulation.The price process is governed by a modified geometric Brownian motion whose drift and diffusion coefficients depend on a Markov chain.The bid and ask prices of a European-type asset are then characterized using conic quantization.展开更多
Selected milestones in the development and use of electrical tomography in powder conveying, slurry processing and multi-phase flow are highlighted. The ability to map concentration in opaque mixtures under process-re...Selected milestones in the development and use of electrical tomography in powder conveying, slurry processing and multi-phase flow are highlighted. The ability to map concentration in opaque mixtures under process-realistic conditions was a major innovation for the method and has had far reaching implications. Subsequent developments have enabled velocity information to be abstracted resulting in the ability to measure component flux and motion.展开更多
In this paper, by using weak dissipative type conditions and weak noncompact conditions, we give the existence of weak solutions of differential equations in weak complete Banach spaces.
基金funded by the 863 Program entitled as"The research and exploration of nutrition fortified food for improving growth and development(2010AA023004)"performed by the Trace Elements Nutrition Key Laboratory of the Ministry of Health
文摘Objective To establish and evaluate a protein serum ferritin (SF) and soluble transferrin receptor microarray method for combined measurement of (sTfR). Methods Microarrayer was used to print both anti-SF antibodies I and anti-sTfR antibodies I on each protein microarray. Anti-SF antibodies II and anti-sTfR antibodies II were used as detection antibodies and goat antibodies coupled to Cy3 were used as antibodies Ill. The detection conditions of the quantitative analysis method for simultaneous measurement of SF and sTfR with protein microarray were optimized and evaluated. The protein microarray was compared with commercially available traditional tests with 26 serum samples. Results By comparison experiment, mouse monoclonal antibodies were chosen as the probes and contact printing was chosen as the printing method. The concentrations of SF and sTfR probes were 0.5 mg/mL and 0.5 mg/mL respectively, while those of SF and sTfR detection antibodies were 5 μg/mL and 0.36 μg/mL respectively. Intra- and inter-assay variability was between 3.26% and 18.38% for all tests. The regression coefficients comparing protein microarray with traditional test assays were better than 0.81 for SF and sTfR. Conclusion The present study has established a protein microarray method for combined measurement of SF and sTfR.
基金Supported by the National Natural Science Foundation of China (No.10925107)Guangdong Province Universities and Colleges Pearl River Scholar Funded Schemethe Fundamental Research Funds for the Central Universities (No.11612314)
文摘This paper concerns the construction and regularity of a transition (probability) function of a nonhomogeneous continuous-time Maxkov process with given transition rates and a general state space. Motivating from a lot of restriction in applications of a transition function with continuous (in t ≥0) and consewative transition rates q(t, x, A), we consider the case that q(t, x, A) axe only required to satisfy a mild measurability (in t ≥ O) condition, which is a generalization of the continuity condition. Under the measurability condition we construct a transition function with the given transition rates, provide a necessary and sufficient condition for it to be regular, and further obtain some interesting additional results.
基金supported by the Hi-Tech Research and Development Program (863) of China (No. 2009AA06Z304)the Macao Environmental Protection Bureauthe National Natural Science Foundation of China (No. 50808169),50808169)
文摘The real-world fuel efficiency and exhaust emission profiles of CO, HC and NOx for light-duty diesel vehicles were investigated. Using a portable emissions measurement system, 16 diesel taxies were tested on different roads in Macao and the data were normalized with the vehicle specific power bin method. The 11 Toyota Corolla diesel taxies have very good fuel economy of (5.9 ± 0.6) L/100 km, while other five diesel taxies showed relatively high values at (8.5 ± 1.7) L/100 km due to the variation in transmission systems and emission control strategies. Compared to similar Corolla gasoline models, the diesel cars confirmed an advantage of ca. 20% higher fuel efficiency. HC and CO emissions of all the 16 taxies are quite low, with the average at (0.05 ± 0.02) g/km and (0.38 ± 0.15) g/km, respectively. The average NOx emission factor of the 11 Corolla taxies is (0.56 ± 0.17) g/km, about three times higher than their gasoline counterparts. Two of the three Hyundai Sonata taxies, configured with exhaust gas recirculation (EGR) + diesel oxidation catalyst (DOC) emission control strategies, indicated significantly higher NO2 emissions and NO2/NOx ratios than other diesel taxies and consequently trigger a concern of possibly adverse impacts on ozone pollution in urban areas with this technology combination. A clear and similar pattern for fuel consumption and for each of the three gaseous pollutant emissions with various road conditions was identified. To save energy and mitigate CO2 emissions as well as other gaseous pollutant emissions in urban area, traffic planning also needs improvement.
文摘This paper introduces and represents conditional coherent risk measures as essential suprema of conditional expectations over a convex set of probability measures and as distorted expectations given a concave distortion function.A model is then developed for the bid and ask prices of a European-type asset by a conic formulation.The price process is governed by a modified geometric Brownian motion whose drift and diffusion coefficients depend on a Markov chain.The bid and ask prices of a European-type asset are then characterized using conic quantization.
基金support of co-workers in the tomography groups at University of Leeds and the University of Manchester with funding to enable us to develop the frontiers of tomography provided by EPSRC (EP/D031257/1)
文摘Selected milestones in the development and use of electrical tomography in powder conveying, slurry processing and multi-phase flow are highlighted. The ability to map concentration in opaque mixtures under process-realistic conditions was a major innovation for the method and has had far reaching implications. Subsequent developments have enabled velocity information to be abstracted resulting in the ability to measure component flux and motion.
基金Project is supportedby the Natural Science Foundation of Shangdong Province.
文摘In this paper, by using weak dissipative type conditions and weak noncompact conditions, we give the existence of weak solutions of differential equations in weak complete Banach spaces.