The coordination mechanism between the career development planning of vocational students and the management of vocational colleges is an important means to improve the quality of education and students’vocational co...The coordination mechanism between the career development planning of vocational students and the management of vocational colleges is an important means to improve the quality of education and students’vocational competitiveness.The application of synergy theory in the field of education emphasizes the interaction and coordination of various elements in the system and pursues the optimization of overall efficiency.Based on the theory of coordination and its relevance to the management of higher vocational colleges,this paper analyzes the current development status and problems of the coordination mechanism and puts forward the strategy of building an efficient coordination mechanism designed to enhance the students’employment competitiveness,promote the all-round development,and provide theoretical and practical support for the reform and development of higher vocational education.展开更多
A comprehensive study was undertaken at Jiaozi coal mine to investigate the development regularity of ground fissures in shallow buried coal seam mining with Karst landform,shedding light on the development type,geogr...A comprehensive study was undertaken at Jiaozi coal mine to investigate the development regularity of ground fissures in shallow buried coal seam mining with Karst landform,shedding light on the development type,geographical distribution,dynamic development process,and failure mechanism of these ground fissures by employing field monitoring,numerical simulation,and theoretical analysis.The findings demonstrate that ground fissure development has an obvious feature of subregion,and its geographical distribution is significantly affected by topography.Tensile type,open type,and stepped type are three different categories of ground fissure.Ground fissures emerge dynamically as the panel advances,and they typically develop with a distance of less than periodic weighting step distance in advance of panel advancing position.Ground fissures present the dynamic development feature,temporary fissure has the ability of self-healing.The dynamic development process of ground fissure with closed-distance coal seam repeated mining is expounded,and the development scale is a dynamic development stage of“closure→expansion→stabilized”on the basis of the original development scale.From the perspective of topsoil deformation,the computation model considering two points movement vectors towards two directions of the gob and the ground surface is established,the development criterion considering the critical deformation value of topsoil is obtained.The mechanical model of hinged structure of inclined body is proposed to clarify the ground fissure development,and the interaction between slope activity and ground fissure development is expounded.These research results fulfill the gap of ground fissures about development regularity and formation mechanism,and can contribute to ground fissure prevention and treatment with Karst landform.展开更多
Autophagy is an evolutionarily conserved degradation pathway of lysosomes(in mammals)and vacuoles(in yeasts and plants)from lower yeasts to higher mammals.It wraps unwanted organelles and damaged proteins in a double-...Autophagy is an evolutionarily conserved degradation pathway of lysosomes(in mammals)and vacuoles(in yeasts and plants)from lower yeasts to higher mammals.It wraps unwanted organelles and damaged proteins in a double-membrane structure to transport them to vacuoles for degradation and recycling.In plants,autophagy functions in adaptation to the environment and maintenance of growth and development.This review systematically describes the autophagy process,biological functions,and regulatory mechanisms occurring during plant growth and development and in response to abiotic stresses.It provides a basis for further theoretical research and guidance of agricultural production.展开更多
With the deepening of the market economy and the big step of urbaniza- tion, the spatial restricted effect of the development of the riverside cities in China is becoming more and more obvious. The river-crossing deve...With the deepening of the market economy and the big step of urbaniza- tion, the spatial restricted effect of the development of the riverside cities in China is becoming more and more obvious. The river-crossing development of cities is imperative. The Riverside New Area has gradually become the key area of urban development and the new economy growth pole. Based on the development history of Nanchang, the evolution of the river-crossing development of Nanchang city was analyzed systematically, and river-crossing development of Nanchang was divided into 3 stages of initial river-crossing development stage, slow river-crossing develop- ment stage and rapid river-crossing development stage. In-depth discussion was made to the dynamic mechanism of the river-crossing development in Nanchang.展开更多
The most recent research findings on the tolerance of fruit trees to cold stress are reviewed from a molecular perspective,including the perception and transduction of low temperature calcium signaling,CBF-dependent m...The most recent research findings on the tolerance of fruit trees to cold stress are reviewed from a molecular perspective,including the perception and transduction of low temperature calcium signaling,CBF-dependent molecular regulatory mechanisms,non-CBF-dependent molecular regulatory mechanisms,and so forth.The objective is to provide a reference basis for further improving the cold resistance of fruit trees and cultivating new varieties of hardy plants.展开更多
With the rapid development of China’s economy,the coordinated development of resident income and GDP has become an important indicator to measure local economic development.How to realize the synergistic growth of th...With the rapid development of China’s economy,the coordinated development of resident income and GDP has become an important indicator to measure local economic development.How to realize the synergistic growth of the two in the new era is of great significance for promoting the sustainable development of the local economy.Based on the theory of the coordinated development of resident income and GDP,this paper will take Shandong Province as an example to analyze the interaction between resident income growth and GDP,find out the influencing factors that restrict the coordinated development of resident income and GDP,and explore the impact of the coordinated development of resident income and GDP on local economic development.Finally,relevant policies will be studied.How to effectively increase residents’income,promote the sustainable and healthy development of the local economy,and put forward relevant suggestions to promote the coordinated development of residents’income and GDP.展开更多
Tight sandstone gas serves as an important unconventional hydrocarbon resource, and outstanding results have been obtained through its discovery both in China and abroad given its great resource potential. However, he...Tight sandstone gas serves as an important unconventional hydrocarbon resource, and outstanding results have been obtained through its discovery both in China and abroad given its great resource potential. However, heated debates and gaps still remain regarding classification standards of tight sandstone gas, and critical controlling factors, accumulation mechanisms, and devel- opment modes of tight sandstone reservoirs are not deter- mined. Tight sandstone gas reservoirs in China are generally characterized by tight strata, widespread distri- bution areas, coal strata supplying gas, complex gas-water relations, and abnormally low gas reservoir pressure. Water and gas reversal patterns have been detected via glass tube and quartz sand modeling, and the presence of critical geological conditions without buoyancy-driven mecha- nisms can thus be assumed. According to the timing of gas charging and reservoir tightening phases, the following three tight sandstone gas reservoir types have been identified: (a) "accumulation-densification" (AD), or the conventional tight type, (b) "densification-accumulation" (DA), or the deep tight type, and (c) the composite tight type. For the AD type, gas charging occurs prior to reser- voir densification, accumulating in higher positions under buoyancy-controlled mechanisms with critical controlling factors such as source kitchens (S), regional overlaying cap rocks (C), gas reservoirs, (D) and low fluid potential areas (P). For the DA type, reservoir densification prior to the gas charging period (GCP) leads to accumulation in depres- sions and slopes largely due to hydrocarbon expansive forces without buoyancy, and critical controlling factors are effective source rocks (S), widely distributed reservoirs (D), stable tectonic settings (W) and universal densification of reservoirs (L). The composite type includes features of the AD type and DA type, and before and after reservoir densification period (RDP), gas charging and accumulation is controlled by early buoyancy and later molecular expansive force respectively. It is widely distributed in anticlinal zones, deep sag areas and slopes, and is con- trolled by source kitchens (S), reservoirs (D), cap rocks (C), stable tectonic settings (W), low fluid potential areas (P), and universal reservoir densification (L). Tight gas resources with great resource potential are widely dis- tributed worldwide, and tight gas in China that presents advantageous reservoir-forming conditions is primarily found in the Ordos, Sichuan, Tarim, Junggar, and Turpan- Hami basins of central-western China. Tight gas has served as the primary impetus for global unconventional natural gas exploration and production under existing technical conditions.展开更多
The increase of atmospheric carbon dioxide and the global warming due to its greenhouse effect resulted in worldwide concerns. On the other hand, carbon dioxide might be considered as a valuable and renewable carbon s...The increase of atmospheric carbon dioxide and the global warming due to its greenhouse effect resulted in worldwide concerns. On the other hand, carbon dioxide might be considered as a valuable and renewable carbon source. One approach to reduce carbon dioxide emissions could be its capture and recycle via transformation into chemicals using the technologies in C1 chemistry. Despite its great interest, there are difficulties in CO2 separation on the one hand, and thermodynamic stability of carbon dioxide molecule rendering its chemical activity low on the other hand. Carbon dioxide has been already used in petrochemical industries for production of limited chemicals such as urea. The utilization of carbon dioxide does not necessarily involve development of new processes, and in certain processes such as methanol synthesis and methane steam reforming, addition of CO2 into the feed results in its utilization and increases carbon efficiency. In other cases, modifications in catalyst and/or processes, or even new catalysts and processes, are necessary. In either case, catalysis plays a crucial role in carbon dioxide conversion and effective catalysts are required for commercial realization of the related processes. Technologies for CO2 utilization are emerging after many years of research and development efforts.展开更多
Warm-sector heavy rainfalls along the south China coast from April to June during 2009-2014 can be divided into two main types based on their low-level circulations. Type I is the southerly pattern with meridional con...Warm-sector heavy rainfalls along the south China coast from April to June during 2009-2014 can be divided into two main types based on their low-level circulations. Type I is the southerly pattern with meridional convergence line at the west of the Pearl River estuary, which is formed by the convergence of southeasterly, southerly, and southwesterly flows. Type II is the southwesterly pattern with a latitudinal convergence line at the east of the Pearl River estuary, which is formed by the convergence of westerly and southwesterly flows. Statistics on 6-hourly heavy rainfall events indicates that, during the afore-mentioned 6 years, there were on average 73.2 occurrences of the southerly pattern and 50.3 occurrences of the southwesterly pattern per year. After the onset of summer monsoon in the South China Sea, the occurrence frequencies of both patterns increase remarkably. The synthetic diagnosis of pattern circulation shows that, at 500 h Pa, for the southerly pattern, there is a broad warm high ridge, and a temperature ridge is behind the high ridge, which causes an obvious warm advection at the high ridge area. There is no frontal region. For the southwesterly pattern, the circulation is a weak trough with a temperature trough behind it. The position of the frontal region is near Yangzi River, and the south China coast is in the warm-sector of the frontal region. At the vertical cross-section of each of the two categories of heavy rainfall, there is a strong vertical motion center stretching to 400 hPa, where the convergence layer in the rainfall region is deep and with several vertical convergence centers overlapping one another. Both types of heavy rainfalls are with abundant water vapor, accompanied with deep convective instability energy layers, and with strong release of latent heat caused by condensation of water vapor. The release of latent heat leads to the warming-up and stretching of the air column, thus strengthens deep convergence and vertical velocity upward. There is a stronger latent heat-release in the southwesterly pattern than in the southerly pattern,while in the southerly pattern, the warm advection at middle and upper levels is stronger than the latent head release.To study the thermo-dynamic development mechanisms, weather research and forecasting model(WRF) numerical simulations are made and the results show that, in the two rainstorm regions, latent heat release warms up the air column, hence significantly increase the depth and strength of the vertical velocity. Moreover, the release of latent heat strengthens convergent circulation at lower levels and weakens divergent circulation at middle levels, whose influence can be as strong as 30%-50% of the wind circulation strength of the two types of the warm-sector heavy rainfall over the south China coast, and further enhances deep convection, promoting warm-sector storm development.展开更多
Smart urban development is an inevitable choice, and is essential to overall strength improvement. It is important to explore an urban smart development path which unites smart growth with driving shrinkage perfectly ...Smart urban development is an inevitable choice, and is essential to overall strength improvement. It is important to explore an urban smart development path which unites smart growth with driving shrinkage perfectly in forming scientific and sustainable development concept and responding to new normal strategic opportunities. Based on statistic data of 294 prefecture-level cities and above in China from 2000 to 2015, we analyzed spatial and temporal evolution of urban smart development in China by constructing a dynamic fitting model of urban land expansion, population growth, and economic development as well as the coefficient of variation of urban smart development(CVSD). Further efforts were then made to consider differential distribution regularity of urban smart development so as to understand the driving mechanisms of heterogeneous classification of urban smart development in China from different scales and scale variation. Our results indicate that: 1) the disordered growth tendency of urban cities in China is overall well controlled in the middle, and late research and it mainly presented a doublet coexistence of shrinkage disordered cities and smart developing cities. It is particularly obvious that Northeast China and East China have regarded shrinkage disordered cities and smart developing cities as main development tendency separately. 2) Areas with basic stability and relative variation were relatively dispersed across the time period, but the proportion was far beyond areas with significant variation. It demonstrates a relative equilibrium spatial and temporal differential evolution pattern of prefecture-level cities and above in China, except for Tongling, Lanzhou and Chaoyang. 3) prefecture-level cities and above in China are mostly characterized by shrinkage disordered and smart development classification under the background of different scale and scale variation from 2000–2015; however, the spatial resonance relation is not obvious. 4) There are many interaction factors forming an important driving mechanism in developing the spatial and temporal pattern of urban smart development in China, including natural geographical factors, industrial structure adjustment, human capital radiation, regional traffic accessibility, and government decision-making intervention.展开更多
With the advent of the era of big data and artificial intelligence, new infrastructure construction(NIC) has attracted the attention of many countries. The development of NIC provides an opportunity to bridge the digi...With the advent of the era of big data and artificial intelligence, new infrastructure construction(NIC) has attracted the attention of many countries. The development of NIC provides an opportunity to bridge the digital divide and narrow the regional gap,providing continuous impetus to further promote economic development. Here, we considered 31 provincial-level administrative units in China(not including Hong Kong, Macao, and Taiwan of China due to data unavailable) and established comprehensive evaluation indicators for the development potential of NIC. Afterward, we used the entropy-weight TOPSIS model to determine the development potential of NIC and analyze its spatio-temporal evolution characteristics. Furthermore, the GeoDetector model was applied to explore the driving mechanism of the NIC development potential. The conclusions were as follows: (1) The Chinese NIC development potential is generally low. The eastern China was the region with the highest development potential year by year, while the development potential in the central China was found to be in an accelerating phase. (2) The evolution of the Chinese NIC development potential’s spatial pattern has been characterized by an inland extension and coastal agglomeration. Moreover, we identified a superior development zone, a rising development zone, an inferior development zone, and a declining development zone. (3) The scope of Chinese NIC development potential agglomeration areas has gradually expanded and its degree has gradually deepened. The range of high-value agglomeration in eastern area gradually expanded and its degree gradually deepened. (4) Investment in innovative talents appears as the core factor affecting the Chinese NIC development potential. Whether acting alone or synergistically with other factors, its promoting effect on Chinese NIC development potential is the strongest.展开更多
With the social and economic development,conflict among the shortage of resources,environmental destruction and economic development is ever more pronounced.In this context,the circular economy was gradually accepted....With the social and economic development,conflict among the shortage of resources,environmental destruction and economic development is ever more pronounced.In this context,the circular economy was gradually accepted.Guided by sustainable development concept and promoted by six external forces,tourism circular economy take tourism micro-cycle model as the core,implement in corporate and social levels,improve resource utilization efficiency,reduce tourism's adverse impacts on the surrounding environment through recycling,reducing and reusing resources,achieve economic,social and environmental development of the organic unity.展开更多
Natural resources and the environment,environmental capacity of China has been approaching the red alert,and long-term accumulation of ecological debt needs to be solved. The transformation of economic development mod...Natural resources and the environment,environmental capacity of China has been approaching the red alert,and long-term accumulation of ecological debt needs to be solved. The transformation of economic development mode and green economic development path are inevitable choices. The complexity and the pressureof the ecological environment governance force Changsha-Zhuzhou-Xiangtan region to change the ecological governance method. The " government-market-society" is taken as the overall framework,to build a diversified body of eco-environment collaborative governance platform. Through collaborative governance among governments,government-market collaborative governance and government-society collaborative governance,ecological capital stock is improvedin the quantity and quality,thus contributing to benigndevelopment of regional economy and society.展开更多
The Clean Development Mechanism,a flexibility mechanism contained in the KyotoProtocol, offers China an important tool to attractinvestment in clean energy technology and processesinto its electricity sector. The Chin...The Clean Development Mechanism,a flexibility mechanism contained in the KyotoProtocol, offers China an important tool to attractinvestment in clean energy technology and processesinto its electricity sector. The Chinese electricitysector places centrally in the country’s economy andenvironment, being a significant contributor to theacid rain and air pollution problems that plague manyof China’s cities and regions, and therefore a focusof many related energy and environmental policies.China’s electricity sector has also been the subjectof a number of economic analyses that have showedthat it contains the highest potential for clean energyinvestment through the Clean DevelopmentMechanism of any economic sector in China. Thismechanism, through the active participation frominvestors in more industrialized countries, can helpalleviate the environmental problems attributable toelectricity generation in China through advancingsuch technology as wind electricity generation, cleancoal technology, high efficient natural gas electricitygeneration, or utilization of coal mine methane. Inthis context, the Clean Development Mechanismalso compliments a range of environmental and energypolicies which are strategizing to encourage thesustainable development of China’s economy.展开更多
Researches about ancient needling,technique,have been made for many decades,whereas the results are discrepant.People tried to use modern science to explore thoroughly about the real structure of acupuncture functions...Researches about ancient needling,technique,have been made for many decades,whereas the results are discrepant.People tried to use modern science to explore thoroughly about the real structure of acupuncture functions.Much more progress has been made than the last century.This review summarized some of the most prevailed theories about the mechanisms of acupuncture and their common applications.And lastly,this article discussed the future development for acupuncture。展开更多
Objective: To study the effect and mechanism of Tip60 regulating DNA on mouse embryo development, and to provide theoretical basis for the study of embryo development. Methods: mice embryos were randomly divided into ...Objective: To study the effect and mechanism of Tip60 regulating DNA on mouse embryo development, and to provide theoretical basis for the study of embryo development. Methods: mice embryos were randomly divided into two groups: control group and experimental group. The embryos of experimental group were given Tip60 inhibitor, the mice of control group were given the same dose of normal saline. The level of Tip60 in the two groups of mice embryos, the effect of Tip60 on p53-p21 pathway, the expression of DNA repair factor 53BP1 protein, the content of active oxygen, the effect of autophagy and apoptosis, and the development of embryos were analyzed. Results: the level of Tip60 in the experimental group was significantly lower than that in the control group;the p53-p21 pathway in the experimental group was activated, the DNA damage of the experimental group was greater, the expression of DNA repair factor was lower, the content of ROS in the experimental group was significantly higher than that in the control group;the autophagy and apoptosis of the experimental group were enhanced;the capsule of the control group was enhanced. The embryogenesis rate of the experimental group was (65.13 ± 4.85)%, and that of the experimental group was (29.36 ± 1.75)%, which was significantly lower than that of the control group. Conclusion: Tip60 can regulate DNA damage and repair by mediating p53-p21 pathway in early mouse embryo development. Inhibition of Tip60 can increase the active oxygen, induce autophagy and over expression of apoptosis in mouse embryo cells, and inhibit the development of embryo to a certain extent. It has important guiding significance to measure the level of Tip60 during embryo culture.展开更多
This paper summarizes the results of the implementation of the CDM in Argentina during the first period of commitment of the Kyoto Protocol. From a total of sixty- five projects ideas, forty-four achieved registration...This paper summarizes the results of the implementation of the CDM in Argentina during the first period of commitment of the Kyoto Protocol. From a total of sixty- five projects ideas, forty-four achieved registration under the CDM EB while the rest remained approved at national level (12), under evaluation (2), suspended (5) or rejected (2). Most of the projects focused on the generation of electricity from renewable energy, mainly wind energy and the use of landfill gas and methane for energy. Emissions reductions achieved 33.4% of the expected CERs up to 2012 with strong differences among sectors. Results demonstrated that under the current Argentina’s energy policy framework, the income by the selling of CERs covered less than 6% of the incremental costs for renewable energy projects. A sensitivity analysis to evaluate the impact of CDM in the coverage of incremental costs for renewable energy based on the prices of both the energy in the local market and the CER demonstrated that the best conditions would only cover 15% of those costs. The contribution of CDM to technology transfer in Argentina was minor considering that 45% of the projects qualified as type III where technological learning and capacity building were limited at the level of operation and maintenance of a foreign technology. Domestic and external barriers that prevented a better performance of CDM projects in terms of GHG mitigation, technology transfer and the contribution to a sustainable development were also analyzed.展开更多
Alzheimer’s disease (AD) is an age-related eurodegenerative disease that represents the most common cause of dementia among the elderly people. With the increasingly aging population, AD has presented an overwhelmi...Alzheimer’s disease (AD) is an age-related eurodegenerative disease that represents the most common cause of dementia among the elderly people. With the increasingly aging population, AD has presented an overwhelming healthcare challenge to modern society; the World Alzheimer Report 2015 has estimated that 46.8 million people worldwide lived with dementia in 2015 and this number will rise to 74.7 million in 2030 and that the total cost of dementia was 818 billion in US$ in 2015 and will reach two trillion in 2030. Post-mortem studies have identified two histopathological hallmarks in the brains of AD patients; extracellular senile plaque with elevated deposition of amyloid β (Aβ) peptides, and intracellular neurofibrillary tangle composed of hyper-phosphorylated microtubule-associated protein tau.Etiologically, progressive neuronal loss within the cerebral cortex and hippocampus regions of the brain leads to irreversible decline in, and eventually complete loss of, memory and other cognitive functions that afflict AD patients. The widely-accepted amyloid cascade hypothesis for AD pathogenesis holds that accumulation and aggregation of neurotoxic Aβ peptides, due to imbalance of their generation and clearance as a result of changes in genetic makeup, aging and/or exposure to environmental risk factors, is a major and early trigger of AD. This hypothesis has continuously gained support by preclinical and clinical studies (Selkoe and Hardy, 2016). However, the intensive and costly drug discovery efforts over the past decades based on such a hypothesis have proved extremely frustrating in developing effective therapeutics to treat or slow down the progress of AD, highlighting the need for more research to improve our understanding towards the cellular and molecular mechanisms by which Aβ peptides bring about neurotoxicity and cognitive dysfunction.展开更多
Global climate change has been identified as the first of the top ten environmental problems in the world. As climate change will have serious effects on the social and economic development and everyday, living of peo...Global climate change has been identified as the first of the top ten environmental problems in the world. As climate change will have serious effects on the social and economic development and everyday, living of people in the world, many of the countries and governments are taking untiring efforts to combat climate change. As one of the important mechanisms of reducing greenhouse gas (GHG) emissions in the Kyoto Protocol, Clean Development Mechanism (CDM) has not only provided chance for developed countries to fulfill greenhouse emission reduction obligations, but also provided an opportunity for developing countries to combat climate change under the sustainable development frame. The dual objectives of developed countries' GHG emissions' reduction obligation achievement and developing cotmtries'sustainable development will be achieved under the CDM. As a country with responsibility; China has been positively developing CDM projects and promoting energy saving and emissions reduction during the three yeors after the Kyoto Protocol came into force, and CDM projects development has always been in the front tank in the world. However; as the vast clime within China, notable differences occur in different regions. In order to promote the CDM development in China, it is necessa^T to have regional CDM capability construction in accordance with the practicality in different regions. Based on the Slat Analysis of developed CDM projects and current CDM development status in China, problems in the CDM development of China, including the inefficiency in small and medium-sized CDM Projects' development, over centralization of CDM development scope and especially the differentiated provincial CDM projects developing capability are pointed out in the paper: What's more, reasons for the problems are analyzed from fire leading.factors, including policy orient, information asymmetry and weak CDM capability, In order to promote CDM projects development in China, a new CDM capability, construction model is put forward in the paper.展开更多
According to the basic principles of institutional economics,the Constitutional system is the underlying causes to promote the economic development.The CPC Central Committee is the source of motivation to promote econ...According to the basic principles of institutional economics,the Constitutional system is the underlying causes to promote the economic development.The CPC Central Committee is the source of motivation to promote economic development by the startup mechanism of Constitution am endment,and the political interpretation of the Constitution is the basic way to promote economic development.The economic development in China has challenged the Constitutional system,calling for the appropriate adjustments to the Constitutional system so as to maintain the sustainable and stable development of the economy in China.展开更多
文摘The coordination mechanism between the career development planning of vocational students and the management of vocational colleges is an important means to improve the quality of education and students’vocational competitiveness.The application of synergy theory in the field of education emphasizes the interaction and coordination of various elements in the system and pursues the optimization of overall efficiency.Based on the theory of coordination and its relevance to the management of higher vocational colleges,this paper analyzes the current development status and problems of the coordination mechanism and puts forward the strategy of building an efficient coordination mechanism designed to enhance the students’employment competitiveness,promote the all-round development,and provide theoretical and practical support for the reform and development of higher vocational education.
基金funded by State Key Laboratory of Strata Intelligent Control and Green Mining Cofounded by Shandong Province and the Ministry of Science and Technology,Shandong University of Science and Technology(Grant No.MDPC2023ZR01)Open Fund of State Key Laboratory of Water Resource Protection and Utilization in Coal Mining(Grant No.WPUKFJJ2019-19)Major research project of Guizhou Provincial Department of Education on innovative groups(Grant No.Qianjiaohe KY[2019]070)。
文摘A comprehensive study was undertaken at Jiaozi coal mine to investigate the development regularity of ground fissures in shallow buried coal seam mining with Karst landform,shedding light on the development type,geographical distribution,dynamic development process,and failure mechanism of these ground fissures by employing field monitoring,numerical simulation,and theoretical analysis.The findings demonstrate that ground fissure development has an obvious feature of subregion,and its geographical distribution is significantly affected by topography.Tensile type,open type,and stepped type are three different categories of ground fissure.Ground fissures emerge dynamically as the panel advances,and they typically develop with a distance of less than periodic weighting step distance in advance of panel advancing position.Ground fissures present the dynamic development feature,temporary fissure has the ability of self-healing.The dynamic development process of ground fissure with closed-distance coal seam repeated mining is expounded,and the development scale is a dynamic development stage of“closure→expansion→stabilized”on the basis of the original development scale.From the perspective of topsoil deformation,the computation model considering two points movement vectors towards two directions of the gob and the ground surface is established,the development criterion considering the critical deformation value of topsoil is obtained.The mechanical model of hinged structure of inclined body is proposed to clarify the ground fissure development,and the interaction between slope activity and ground fissure development is expounded.These research results fulfill the gap of ground fissures about development regularity and formation mechanism,and can contribute to ground fissure prevention and treatment with Karst landform.
基金the Shandong Natural Science Foundation(ZR2020QC114)the National Natural Science Foundation of China(32001542,32001545)+1 种基金the Agricultural Variety Improvement Project of Shandong Province(2021LZGC013)the Shandong Academy of Agricultural Sciences Innovation Project(CXGC2023A01,CXGC2023C02).
文摘Autophagy is an evolutionarily conserved degradation pathway of lysosomes(in mammals)and vacuoles(in yeasts and plants)from lower yeasts to higher mammals.It wraps unwanted organelles and damaged proteins in a double-membrane structure to transport them to vacuoles for degradation and recycling.In plants,autophagy functions in adaptation to the environment and maintenance of growth and development.This review systematically describes the autophagy process,biological functions,and regulatory mechanisms occurring during plant growth and development and in response to abiotic stresses.It provides a basis for further theoretical research and guidance of agricultural production.
文摘With the deepening of the market economy and the big step of urbaniza- tion, the spatial restricted effect of the development of the riverside cities in China is becoming more and more obvious. The river-crossing development of cities is imperative. The Riverside New Area has gradually become the key area of urban development and the new economy growth pole. Based on the development history of Nanchang, the evolution of the river-crossing development of Nanchang city was analyzed systematically, and river-crossing development of Nanchang was divided into 3 stages of initial river-crossing development stage, slow river-crossing develop- ment stage and rapid river-crossing development stage. In-depth discussion was made to the dynamic mechanism of the river-crossing development in Nanchang.
基金Supported by Basic Research Fund of Hebei Academy of Agriculture and Forestry Sciences(2024020202)"Three-Three-Three"Talent Project of Hebei Province(C20231157)+2 种基金Science and Technology Innovation Project of Hebei Academy of Agriculture and Forestry Sciences(2022KJCXZX-CGS-7)Hebei Agricultural Industry Research System(HBCT2024170406)Key Research and Development Program of Hebei Province(21326308D-1-2).
文摘The most recent research findings on the tolerance of fruit trees to cold stress are reviewed from a molecular perspective,including the perception and transduction of low temperature calcium signaling,CBF-dependent molecular regulatory mechanisms,non-CBF-dependent molecular regulatory mechanisms,and so forth.The objective is to provide a reference basis for further improving the cold resistance of fruit trees and cultivating new varieties of hardy plants.
文摘With the rapid development of China’s economy,the coordinated development of resident income and GDP has become an important indicator to measure local economic development.How to realize the synergistic growth of the two in the new era is of great significance for promoting the sustainable development of the local economy.Based on the theory of the coordinated development of resident income and GDP,this paper will take Shandong Province as an example to analyze the interaction between resident income growth and GDP,find out the influencing factors that restrict the coordinated development of resident income and GDP,and explore the impact of the coordinated development of resident income and GDP on local economic development.Finally,relevant policies will be studied.How to effectively increase residents’income,promote the sustainable and healthy development of the local economy,and put forward relevant suggestions to promote the coordinated development of residents’income and GDP.
基金supported by the National Natural Science Foundation of China (No. 41472112)the National Major Projects (No. 2011ZX05018002)
文摘Tight sandstone gas serves as an important unconventional hydrocarbon resource, and outstanding results have been obtained through its discovery both in China and abroad given its great resource potential. However, heated debates and gaps still remain regarding classification standards of tight sandstone gas, and critical controlling factors, accumulation mechanisms, and devel- opment modes of tight sandstone reservoirs are not deter- mined. Tight sandstone gas reservoirs in China are generally characterized by tight strata, widespread distri- bution areas, coal strata supplying gas, complex gas-water relations, and abnormally low gas reservoir pressure. Water and gas reversal patterns have been detected via glass tube and quartz sand modeling, and the presence of critical geological conditions without buoyancy-driven mecha- nisms can thus be assumed. According to the timing of gas charging and reservoir tightening phases, the following three tight sandstone gas reservoir types have been identified: (a) "accumulation-densification" (AD), or the conventional tight type, (b) "densification-accumulation" (DA), or the deep tight type, and (c) the composite tight type. For the AD type, gas charging occurs prior to reser- voir densification, accumulating in higher positions under buoyancy-controlled mechanisms with critical controlling factors such as source kitchens (S), regional overlaying cap rocks (C), gas reservoirs, (D) and low fluid potential areas (P). For the DA type, reservoir densification prior to the gas charging period (GCP) leads to accumulation in depres- sions and slopes largely due to hydrocarbon expansive forces without buoyancy, and critical controlling factors are effective source rocks (S), widely distributed reservoirs (D), stable tectonic settings (W) and universal densification of reservoirs (L). The composite type includes features of the AD type and DA type, and before and after reservoir densification period (RDP), gas charging and accumulation is controlled by early buoyancy and later molecular expansive force respectively. It is widely distributed in anticlinal zones, deep sag areas and slopes, and is con- trolled by source kitchens (S), reservoirs (D), cap rocks (C), stable tectonic settings (W), low fluid potential areas (P), and universal reservoir densification (L). Tight gas resources with great resource potential are widely dis- tributed worldwide, and tight gas in China that presents advantageous reservoir-forming conditions is primarily found in the Ordos, Sichuan, Tarim, Junggar, and Turpan- Hami basins of central-western China. Tight gas has served as the primary impetus for global unconventional natural gas exploration and production under existing technical conditions.
文摘The increase of atmospheric carbon dioxide and the global warming due to its greenhouse effect resulted in worldwide concerns. On the other hand, carbon dioxide might be considered as a valuable and renewable carbon source. One approach to reduce carbon dioxide emissions could be its capture and recycle via transformation into chemicals using the technologies in C1 chemistry. Despite its great interest, there are difficulties in CO2 separation on the one hand, and thermodynamic stability of carbon dioxide molecule rendering its chemical activity low on the other hand. Carbon dioxide has been already used in petrochemical industries for production of limited chemicals such as urea. The utilization of carbon dioxide does not necessarily involve development of new processes, and in certain processes such as methanol synthesis and methane steam reforming, addition of CO2 into the feed results in its utilization and increases carbon efficiency. In other cases, modifications in catalyst and/or processes, or even new catalysts and processes, are necessary. In either case, catalysis plays a crucial role in carbon dioxide conversion and effective catalysts are required for commercial realization of the related processes. Technologies for CO2 utilization are emerging after many years of research and development efforts.
基金National Natural Science Foundation of China,“The Dynamic Structures and Maintaining Mechanisms of Oceanic Meso-scale Eddies”(41276033)National Natural Science Foundation of China Youth Science Fund Project “Research on Intelligent Identification,Forecast and Early-warning of Downburst”(41805033)
文摘Warm-sector heavy rainfalls along the south China coast from April to June during 2009-2014 can be divided into two main types based on their low-level circulations. Type I is the southerly pattern with meridional convergence line at the west of the Pearl River estuary, which is formed by the convergence of southeasterly, southerly, and southwesterly flows. Type II is the southwesterly pattern with a latitudinal convergence line at the east of the Pearl River estuary, which is formed by the convergence of westerly and southwesterly flows. Statistics on 6-hourly heavy rainfall events indicates that, during the afore-mentioned 6 years, there were on average 73.2 occurrences of the southerly pattern and 50.3 occurrences of the southwesterly pattern per year. After the onset of summer monsoon in the South China Sea, the occurrence frequencies of both patterns increase remarkably. The synthetic diagnosis of pattern circulation shows that, at 500 h Pa, for the southerly pattern, there is a broad warm high ridge, and a temperature ridge is behind the high ridge, which causes an obvious warm advection at the high ridge area. There is no frontal region. For the southwesterly pattern, the circulation is a weak trough with a temperature trough behind it. The position of the frontal region is near Yangzi River, and the south China coast is in the warm-sector of the frontal region. At the vertical cross-section of each of the two categories of heavy rainfall, there is a strong vertical motion center stretching to 400 hPa, where the convergence layer in the rainfall region is deep and with several vertical convergence centers overlapping one another. Both types of heavy rainfalls are with abundant water vapor, accompanied with deep convective instability energy layers, and with strong release of latent heat caused by condensation of water vapor. The release of latent heat leads to the warming-up and stretching of the air column, thus strengthens deep convergence and vertical velocity upward. There is a stronger latent heat-release in the southwesterly pattern than in the southerly pattern,while in the southerly pattern, the warm advection at middle and upper levels is stronger than the latent head release.To study the thermo-dynamic development mechanisms, weather research and forecasting model(WRF) numerical simulations are made and the results show that, in the two rainstorm regions, latent heat release warms up the air column, hence significantly increase the depth and strength of the vertical velocity. Moreover, the release of latent heat strengthens convergent circulation at lower levels and weakens divergent circulation at middle levels, whose influence can be as strong as 30%-50% of the wind circulation strength of the two types of the warm-sector heavy rainfall over the south China coast, and further enhances deep convection, promoting warm-sector storm development.
基金Under the auspices of National Natural Science Foundation of China(No.41101548)Philosophy and Social Science Research Program of Heilongjiang Province in 2016(No.16JBL01)+1 种基金Key Research Projects of Economic and Social Development in Heilongjiang Province(No.JD2016014)Human Civilization and Social Science Supportive Program for Excellent Young Scholars of Harbin Normal University(No.SYQ2014-06)
文摘Smart urban development is an inevitable choice, and is essential to overall strength improvement. It is important to explore an urban smart development path which unites smart growth with driving shrinkage perfectly in forming scientific and sustainable development concept and responding to new normal strategic opportunities. Based on statistic data of 294 prefecture-level cities and above in China from 2000 to 2015, we analyzed spatial and temporal evolution of urban smart development in China by constructing a dynamic fitting model of urban land expansion, population growth, and economic development as well as the coefficient of variation of urban smart development(CVSD). Further efforts were then made to consider differential distribution regularity of urban smart development so as to understand the driving mechanisms of heterogeneous classification of urban smart development in China from different scales and scale variation. Our results indicate that: 1) the disordered growth tendency of urban cities in China is overall well controlled in the middle, and late research and it mainly presented a doublet coexistence of shrinkage disordered cities and smart developing cities. It is particularly obvious that Northeast China and East China have regarded shrinkage disordered cities and smart developing cities as main development tendency separately. 2) Areas with basic stability and relative variation were relatively dispersed across the time period, but the proportion was far beyond areas with significant variation. It demonstrates a relative equilibrium spatial and temporal differential evolution pattern of prefecture-level cities and above in China, except for Tongling, Lanzhou and Chaoyang. 3) prefecture-level cities and above in China are mostly characterized by shrinkage disordered and smart development classification under the background of different scale and scale variation from 2000–2015; however, the spatial resonance relation is not obvious. 4) There are many interaction factors forming an important driving mechanism in developing the spatial and temporal pattern of urban smart development in China, including natural geographical factors, industrial structure adjustment, human capital radiation, regional traffic accessibility, and government decision-making intervention.
文摘With the advent of the era of big data and artificial intelligence, new infrastructure construction(NIC) has attracted the attention of many countries. The development of NIC provides an opportunity to bridge the digital divide and narrow the regional gap,providing continuous impetus to further promote economic development. Here, we considered 31 provincial-level administrative units in China(not including Hong Kong, Macao, and Taiwan of China due to data unavailable) and established comprehensive evaluation indicators for the development potential of NIC. Afterward, we used the entropy-weight TOPSIS model to determine the development potential of NIC and analyze its spatio-temporal evolution characteristics. Furthermore, the GeoDetector model was applied to explore the driving mechanism of the NIC development potential. The conclusions were as follows: (1) The Chinese NIC development potential is generally low. The eastern China was the region with the highest development potential year by year, while the development potential in the central China was found to be in an accelerating phase. (2) The evolution of the Chinese NIC development potential’s spatial pattern has been characterized by an inland extension and coastal agglomeration. Moreover, we identified a superior development zone, a rising development zone, an inferior development zone, and a declining development zone. (3) The scope of Chinese NIC development potential agglomeration areas has gradually expanded and its degree has gradually deepened. The range of high-value agglomeration in eastern area gradually expanded and its degree gradually deepened. (4) Investment in innovative talents appears as the core factor affecting the Chinese NIC development potential. Whether acting alone or synergistically with other factors, its promoting effect on Chinese NIC development potential is the strongest.
文摘With the social and economic development,conflict among the shortage of resources,environmental destruction and economic development is ever more pronounced.In this context,the circular economy was gradually accepted.Guided by sustainable development concept and promoted by six external forces,tourism circular economy take tourism micro-cycle model as the core,implement in corporate and social levels,improve resource utilization efficiency,reduce tourism's adverse impacts on the surrounding environment through recycling,reducing and reusing resources,achieve economic,social and environmental development of the organic unity.
基金Supported by Fund Project of Hunan Provincial Social Science Association(XSP18YBC143,16YBX008)
文摘Natural resources and the environment,environmental capacity of China has been approaching the red alert,and long-term accumulation of ecological debt needs to be solved. The transformation of economic development mode and green economic development path are inevitable choices. The complexity and the pressureof the ecological environment governance force Changsha-Zhuzhou-Xiangtan region to change the ecological governance method. The " government-market-society" is taken as the overall framework,to build a diversified body of eco-environment collaborative governance platform. Through collaborative governance among governments,government-market collaborative governance and government-society collaborative governance,ecological capital stock is improvedin the quantity and quality,thus contributing to benigndevelopment of regional economy and society.
文摘The Clean Development Mechanism,a flexibility mechanism contained in the KyotoProtocol, offers China an important tool to attractinvestment in clean energy technology and processesinto its electricity sector. The Chinese electricitysector places centrally in the country’s economy andenvironment, being a significant contributor to theacid rain and air pollution problems that plague manyof China’s cities and regions, and therefore a focusof many related energy and environmental policies.China’s electricity sector has also been the subjectof a number of economic analyses that have showedthat it contains the highest potential for clean energyinvestment through the Clean DevelopmentMechanism of any economic sector in China. Thismechanism, through the active participation frominvestors in more industrialized countries, can helpalleviate the environmental problems attributable toelectricity generation in China through advancingsuch technology as wind electricity generation, cleancoal technology, high efficient natural gas electricitygeneration, or utilization of coal mine methane. Inthis context, the Clean Development Mechanismalso compliments a range of environmental and energypolicies which are strategizing to encourage thesustainable development of China’s economy.
文摘Researches about ancient needling,technique,have been made for many decades,whereas the results are discrepant.People tried to use modern science to explore thoroughly about the real structure of acupuncture functions.Much more progress has been made than the last century.This review summarized some of the most prevailed theories about the mechanisms of acupuncture and their common applications.And lastly,this article discussed the future development for acupuncture。
基金Scientific research project of Hunan provincial health commission(No.C2019130).
文摘Objective: To study the effect and mechanism of Tip60 regulating DNA on mouse embryo development, and to provide theoretical basis for the study of embryo development. Methods: mice embryos were randomly divided into two groups: control group and experimental group. The embryos of experimental group were given Tip60 inhibitor, the mice of control group were given the same dose of normal saline. The level of Tip60 in the two groups of mice embryos, the effect of Tip60 on p53-p21 pathway, the expression of DNA repair factor 53BP1 protein, the content of active oxygen, the effect of autophagy and apoptosis, and the development of embryos were analyzed. Results: the level of Tip60 in the experimental group was significantly lower than that in the control group;the p53-p21 pathway in the experimental group was activated, the DNA damage of the experimental group was greater, the expression of DNA repair factor was lower, the content of ROS in the experimental group was significantly higher than that in the control group;the autophagy and apoptosis of the experimental group were enhanced;the capsule of the control group was enhanced. The embryogenesis rate of the experimental group was (65.13 ± 4.85)%, and that of the experimental group was (29.36 ± 1.75)%, which was significantly lower than that of the control group. Conclusion: Tip60 can regulate DNA damage and repair by mediating p53-p21 pathway in early mouse embryo development. Inhibition of Tip60 can increase the active oxygen, induce autophagy and over expression of apoptosis in mouse embryo cells, and inhibit the development of embryo to a certain extent. It has important guiding significance to measure the level of Tip60 during embryo culture.
文摘This paper summarizes the results of the implementation of the CDM in Argentina during the first period of commitment of the Kyoto Protocol. From a total of sixty- five projects ideas, forty-four achieved registration under the CDM EB while the rest remained approved at national level (12), under evaluation (2), suspended (5) or rejected (2). Most of the projects focused on the generation of electricity from renewable energy, mainly wind energy and the use of landfill gas and methane for energy. Emissions reductions achieved 33.4% of the expected CERs up to 2012 with strong differences among sectors. Results demonstrated that under the current Argentina’s energy policy framework, the income by the selling of CERs covered less than 6% of the incremental costs for renewable energy projects. A sensitivity analysis to evaluate the impact of CDM in the coverage of incremental costs for renewable energy based on the prices of both the energy in the local market and the CER demonstrated that the best conditions would only cover 15% of those costs. The contribution of CDM to technology transfer in Argentina was minor considering that 45% of the projects qualified as type III where technological learning and capacity building were limited at the level of operation and maintenance of a foreign technology. Domestic and external barriers that prevented a better performance of CDM projects in terms of GHG mitigation, technology transfer and the contribution to a sustainable development were also analyzed.
基金supported in parts by grants from the Disciplinary Group of Psychology and Neuroscience Xinxiang Medical University,China(2016PN-KFKT-06)Department of Education of Henan Province,China(16IRTSTHN020)+1 种基金the National Natural Science Foundation of China(31471118)UK Alzheimer’s Research Trust(ART/PPG2009A/2)
文摘Alzheimer’s disease (AD) is an age-related eurodegenerative disease that represents the most common cause of dementia among the elderly people. With the increasingly aging population, AD has presented an overwhelming healthcare challenge to modern society; the World Alzheimer Report 2015 has estimated that 46.8 million people worldwide lived with dementia in 2015 and this number will rise to 74.7 million in 2030 and that the total cost of dementia was 818 billion in US$ in 2015 and will reach two trillion in 2030. Post-mortem studies have identified two histopathological hallmarks in the brains of AD patients; extracellular senile plaque with elevated deposition of amyloid β (Aβ) peptides, and intracellular neurofibrillary tangle composed of hyper-phosphorylated microtubule-associated protein tau.Etiologically, progressive neuronal loss within the cerebral cortex and hippocampus regions of the brain leads to irreversible decline in, and eventually complete loss of, memory and other cognitive functions that afflict AD patients. The widely-accepted amyloid cascade hypothesis for AD pathogenesis holds that accumulation and aggregation of neurotoxic Aβ peptides, due to imbalance of their generation and clearance as a result of changes in genetic makeup, aging and/or exposure to environmental risk factors, is a major and early trigger of AD. This hypothesis has continuously gained support by preclinical and clinical studies (Selkoe and Hardy, 2016). However, the intensive and costly drug discovery efforts over the past decades based on such a hypothesis have proved extremely frustrating in developing effective therapeutics to treat or slow down the progress of AD, highlighting the need for more research to improve our understanding towards the cellular and molecular mechanisms by which Aβ peptides bring about neurotoxicity and cognitive dysfunction.
基金supported by National Key Project of ScientificTechnical Supporting Programs Funded by Ministry of Science & Technology of China in the 11th Five-Year Plan (Grant No.2007BAC03A04)
文摘Global climate change has been identified as the first of the top ten environmental problems in the world. As climate change will have serious effects on the social and economic development and everyday, living of people in the world, many of the countries and governments are taking untiring efforts to combat climate change. As one of the important mechanisms of reducing greenhouse gas (GHG) emissions in the Kyoto Protocol, Clean Development Mechanism (CDM) has not only provided chance for developed countries to fulfill greenhouse emission reduction obligations, but also provided an opportunity for developing countries to combat climate change under the sustainable development frame. The dual objectives of developed countries' GHG emissions' reduction obligation achievement and developing cotmtries'sustainable development will be achieved under the CDM. As a country with responsibility; China has been positively developing CDM projects and promoting energy saving and emissions reduction during the three yeors after the Kyoto Protocol came into force, and CDM projects development has always been in the front tank in the world. However; as the vast clime within China, notable differences occur in different regions. In order to promote the CDM development in China, it is necessa^T to have regional CDM capability construction in accordance with the practicality in different regions. Based on the Slat Analysis of developed CDM projects and current CDM development status in China, problems in the CDM development of China, including the inefficiency in small and medium-sized CDM Projects' development, over centralization of CDM development scope and especially the differentiated provincial CDM projects developing capability are pointed out in the paper: What's more, reasons for the problems are analyzed from fire leading.factors, including policy orient, information asymmetry and weak CDM capability, In order to promote CDM projects development in China, a new CDM capability, construction model is put forward in the paper.
文摘According to the basic principles of institutional economics,the Constitutional system is the underlying causes to promote the economic development.The CPC Central Committee is the source of motivation to promote economic development by the startup mechanism of Constitution am endment,and the political interpretation of the Constitution is the basic way to promote economic development.The economic development in China has challenged the Constitutional system,calling for the appropriate adjustments to the Constitutional system so as to maintain the sustainable and stable development of the economy in China.