The Northeastern China cold vortex(NCCV)is one type of strong cyclonic vortex that occurs near Northeastern China(NEC),and NCCV activities are typically accompanied by a series of hazardous weather.This paper employed...The Northeastern China cold vortex(NCCV)is one type of strong cyclonic vortex that occurs near Northeastern China(NEC),and NCCV activities are typically accompanied by a series of hazardous weather.This paper employed an automatic algorithm to identify the NCCVs from 1979 to 2018 and analyzed their circulation patterns and climatic impacts by using the defined NCCV intensity index(NCCVI).The analysis revealed that the NCCV activities in summer exhibited a strong inter-annual variability,with an obvious periodicity of 3-4 years and 6-7 years,but without significant trends.In years when the NCCVI was high,NEC experienced negative geopotential height anomalies,cyclonic circulation,and cooler temperature anomalies,which were conducive to the maintenance and development of NCCV activities.Furthermore,large amounts of water vapor converged in NEC through two transportation routes as the NCCVs intensified,leading to a significant positive(negative)correlation with the summer precipitation(surface temperature)in NEC.The Atlantic sea surface temperature(SST)anomalies were closely related to summer NCCV activities.As the Atlantic SST rose,large amounts of surface sensible and latent heat flux were transported into the lower troposphere,inducing a positive geopotential height anomaly that occurred on the east side of the heat source.As a result,an eastward diverging flow was formed in the upper troposphere and propagated downstream,i.e.,the eastward propagating Rossby wave train,which eventually led to a coupled circulation in the Ural Mountains and NEC,as well as more intensive NCCV activities in summer.展开更多
The increase of atmospheric carbon dioxide and the global warming due to its greenhouse effect resulted in worldwide concerns. On the other hand, carbon dioxide might be considered as a valuable and renewable carbon s...The increase of atmospheric carbon dioxide and the global warming due to its greenhouse effect resulted in worldwide concerns. On the other hand, carbon dioxide might be considered as a valuable and renewable carbon source. One approach to reduce carbon dioxide emissions could be its capture and recycle via transformation into chemicals using the technologies in C1 chemistry. Despite its great interest, there are difficulties in CO2 separation on the one hand, and thermodynamic stability of carbon dioxide molecule rendering its chemical activity low on the other hand. Carbon dioxide has been already used in petrochemical industries for production of limited chemicals such as urea. The utilization of carbon dioxide does not necessarily involve development of new processes, and in certain processes such as methanol synthesis and methane steam reforming, addition of CO2 into the feed results in its utilization and increases carbon efficiency. In other cases, modifications in catalyst and/or processes, or even new catalysts and processes, are necessary. In either case, catalysis plays a crucial role in carbon dioxide conversion and effective catalysts are required for commercial realization of the related processes. Technologies for CO2 utilization are emerging after many years of research and development efforts.展开更多
Alzheimer’s disease (AD) is an age-related eurodegenerative disease that represents the most common cause of dementia among the elderly people. With the increasingly aging population, AD has presented an overwhelmi...Alzheimer’s disease (AD) is an age-related eurodegenerative disease that represents the most common cause of dementia among the elderly people. With the increasingly aging population, AD has presented an overwhelming healthcare challenge to modern society; the World Alzheimer Report 2015 has estimated that 46.8 million people worldwide lived with dementia in 2015 and this number will rise to 74.7 million in 2030 and that the total cost of dementia was 818 billion in US$ in 2015 and will reach two trillion in 2030. Post-mortem studies have identified two histopathological hallmarks in the brains of AD patients; extracellular senile plaque with elevated deposition of amyloid β (Aβ) peptides, and intracellular neurofibrillary tangle composed of hyper-phosphorylated microtubule-associated protein tau.Etiologically, progressive neuronal loss within the cerebral cortex and hippocampus regions of the brain leads to irreversible decline in, and eventually complete loss of, memory and other cognitive functions that afflict AD patients. The widely-accepted amyloid cascade hypothesis for AD pathogenesis holds that accumulation and aggregation of neurotoxic Aβ peptides, due to imbalance of their generation and clearance as a result of changes in genetic makeup, aging and/or exposure to environmental risk factors, is a major and early trigger of AD. This hypothesis has continuously gained support by preclinical and clinical studies (Selkoe and Hardy, 2016). However, the intensive and costly drug discovery efforts over the past decades based on such a hypothesis have proved extremely frustrating in developing effective therapeutics to treat or slow down the progress of AD, highlighting the need for more research to improve our understanding towards the cellular and molecular mechanisms by which Aβ peptides bring about neurotoxicity and cognitive dysfunction.展开更多
China is now facing huge pressure from both the domestic concern of energy security and the global community's call for emission reduction commitment.As one of the major energy consumers and greenhouse gas emitter...China is now facing huge pressure from both the domestic concern of energy security and the global community's call for emission reduction commitment.As one of the major energy consumers and greenhouse gas emitters,China's iron and steel industry has a huge clean development mechanism(CDM) potential.This article both quantitatively and qualitatively analyzes the current status of CDM project activities in the iron and steel industry in China,including characteristics of approved project types,applicable methodologies,and potential technology fields.From the perspective of project implementation,the article summarizes development barriers such as high investment risk,difficulty in project identification,strict requirements on PPDs,long registration waiting time,and etc.Policy suggestions are also put forwarded to help better promote the development of CDM projects in the iron and steel industry.展开更多
The Clean Development Mechanism,a flexibility mechanism contained in the KyotoProtocol, offers China an important tool to attractinvestment in clean energy technology and processesinto its electricity sector. The Chin...The Clean Development Mechanism,a flexibility mechanism contained in the KyotoProtocol, offers China an important tool to attractinvestment in clean energy technology and processesinto its electricity sector. The Chinese electricitysector places centrally in the country’s economy andenvironment, being a significant contributor to theacid rain and air pollution problems that plague manyof China’s cities and regions, and therefore a focusof many related energy and environmental policies.China’s electricity sector has also been the subjectof a number of economic analyses that have showedthat it contains the highest potential for clean energyinvestment through the Clean DevelopmentMechanism of any economic sector in China. Thismechanism, through the active participation frominvestors in more industrialized countries, can helpalleviate the environmental problems attributable toelectricity generation in China through advancingsuch technology as wind electricity generation, cleancoal technology, high efficient natural gas electricitygeneration, or utilization of coal mine methane. Inthis context, the Clean Development Mechanismalso compliments a range of environmental and energypolicies which are strategizing to encourage thesustainable development of China’s economy.展开更多
There are abundant energy reserves such as oil,natural gas,hydrate,and wind energy in the ocean.Countries around the globe are competing to advance their marine energy development technologies.The exploitation of mari...There are abundant energy reserves such as oil,natural gas,hydrate,and wind energy in the ocean.Countries around the globe are competing to advance their marine energy development technologies.The exploitation of marine resources relies on cutting-edge industrial equipment.After decades of R&D endeavors,China has obtained most of the key technologies for the design,production,testing,and field application of marine energy development equipment(Xie and Zeng,2021).展开更多
This paper presents a three-stage hypothesis on the development of creative industrial clusters, which includes stages of agglomeration, interfacing, and network development. In the first stage, micro-entities concent...This paper presents a three-stage hypothesis on the development of creative industrial clusters, which includes stages of agglomeration, interfacing, and network development. In the first stage, micro-entities concentrate geographically in a creative industrial cluster in search of resources. The second stage reflects the need for building identity. Finally, the third stage is the outcome of multi-dimensional expansion. As a creative industrial cluster develops, its focus moves from geographic concentration to division of labor and the creation of novel systems. Using this three-stage framework, this paper conducts an empirical study on Beijing's 798 District ("798"). Our study finds that the "self-destruction "phenomenon (which appeared after 798 had reached the stage of network development in a low-level capacity) is essentially the product of a squeezing effect of commercial prosperity on art production. Our study further examines four models of art-commerce integration and explains the ways in which creative industrial clusters are different from conventional industrial clusters: a creative cluster is a platform of integration for culture, commerce, and technology. Its course of development is characterized by novelty, emergence of identity through interfacing, and network cooperation.展开更多
This paper summarizes the results of the implementation of the CDM in Argentina during the first period of commitment of the Kyoto Protocol. From a total of sixty- five projects ideas, forty-four achieved registration...This paper summarizes the results of the implementation of the CDM in Argentina during the first period of commitment of the Kyoto Protocol. From a total of sixty- five projects ideas, forty-four achieved registration under the CDM EB while the rest remained approved at national level (12), under evaluation (2), suspended (5) or rejected (2). Most of the projects focused on the generation of electricity from renewable energy, mainly wind energy and the use of landfill gas and methane for energy. Emissions reductions achieved 33.4% of the expected CERs up to 2012 with strong differences among sectors. Results demonstrated that under the current Argentina’s energy policy framework, the income by the selling of CERs covered less than 6% of the incremental costs for renewable energy projects. A sensitivity analysis to evaluate the impact of CDM in the coverage of incremental costs for renewable energy based on the prices of both the energy in the local market and the CER demonstrated that the best conditions would only cover 15% of those costs. The contribution of CDM to technology transfer in Argentina was minor considering that 45% of the projects qualified as type III where technological learning and capacity building were limited at the level of operation and maintenance of a foreign technology. Domestic and external barriers that prevented a better performance of CDM projects in terms of GHG mitigation, technology transfer and the contribution to a sustainable development were also analyzed.展开更多
Since the launch of the economic reform and opening to the outside world, China has seen rapid growth in its export of mechanical and electrical products, with its export
Global climate change has been identified as the first of the top ten environmental problems in the world. As climate change will have serious effects on the social and economic development and everyday, living of peo...Global climate change has been identified as the first of the top ten environmental problems in the world. As climate change will have serious effects on the social and economic development and everyday, living of people in the world, many of the countries and governments are taking untiring efforts to combat climate change. As one of the important mechanisms of reducing greenhouse gas (GHG) emissions in the Kyoto Protocol, Clean Development Mechanism (CDM) has not only provided chance for developed countries to fulfill greenhouse emission reduction obligations, but also provided an opportunity for developing countries to combat climate change under the sustainable development frame. The dual objectives of developed countries' GHG emissions' reduction obligation achievement and developing cotmtries'sustainable development will be achieved under the CDM. As a country with responsibility; China has been positively developing CDM projects and promoting energy saving and emissions reduction during the three yeors after the Kyoto Protocol came into force, and CDM projects development has always been in the front tank in the world. However; as the vast clime within China, notable differences occur in different regions. In order to promote the CDM development in China, it is necessa^T to have regional CDM capability construction in accordance with the practicality in different regions. Based on the Slat Analysis of developed CDM projects and current CDM development status in China, problems in the CDM development of China, including the inefficiency in small and medium-sized CDM Projects' development, over centralization of CDM development scope and especially the differentiated provincial CDM projects developing capability are pointed out in the paper: What's more, reasons for the problems are analyzed from fire leading.factors, including policy orient, information asymmetry and weak CDM capability, In order to promote CDM projects development in China, a new CDM capability, construction model is put forward in the paper.展开更多
Based on the status and characteristics of Clean Development Mechanism (CDM) renewable energy project and the mode of cyclic economy, aimed at achieving the maximum capacity of carbon sinks in the system, Lvjin Jiay...Based on the status and characteristics of Clean Development Mechanism (CDM) renewable energy project and the mode of cyclic economy, aimed at achieving the maximum capacity of carbon sinks in the system, Lvjin Jiayuan—New Countryside Distripark CDM project in Wuchuan County was taken as an example for developing an interval linear programming (ILP) model to optimize the crops planting scheme and cows breeding scheme by using interval optimal method. The case showed that the optimized crops planting scheme and cows breeding scheme obtained from the optimal model was reasonable with relatively preferable overall performance. In the context of meeting economic benefits and fertilizer, electricity demand, [231 287.8, 273 312.7] t of CO2 could be absorbed and fixed, which had increased by [12.94, 33.46]% compared with the feasibility scheme of case project and provided technical support for making the decision in CDM project.展开更多
Tamarix nabkha is one of the most widespread nabkhas, distributing in the arid region of China. Based on the observations outdoors and the simulation experiments in laboratories, analysis in this paper refers to the b...Tamarix nabkha is one of the most widespread nabkhas, distributing in the arid region of China. Based on the observations outdoors and the simulation experiments in laboratories, analysis in this paper refers to the biological geomorphologic features and growth process of Tamarix nabkhas in the middle and lower reaches of the Hotan River, Xinjiang. And the results indicate that the ecological type of Tamarix in the study area is a kind of Tugaic soil habitat based on the deep soil of the Populus Diversifolia forests and shrubs. This type of habitat can be divided into three kinds of sub-habitats which demonstrate the features of ecological environment of Tamarix nabkhas during the differential developed phases. Meanwhile, the Tamar, ix nabkha can exert intensified disturbance current on wind-sand flow on the ground,and its root and stems not only have strong potential of sprouting but are characteristic of wind erosion-tolerance, resistance to be buried by sand and respectively tough rigid of the lignified branches, for it has a rather longer life-time. Thus, the wind speed profile influenced by the Tamarix nabkha is different from the Phragmites nabkha and Alhagi nabkha. And the structure of the wind flow is beneficial to aeolian sand accumulating in/around Tamarix shrub, which can create unique Tamarix nabkhas with higher average gradient and longer periodicity of life. Tamarix nabkha evolution in the area experienced three stages: growth stage, mature and steady stage and withering stage. In each stage, morphological features and geomorphic process of Tamarix nabkha are different due to the discrep- ant interaction between the nabkha and aeolian sand flow.展开更多
In this paper, a heavy sea fog event occurring over the Yellow Sea on 11 April 2004 was investigated based upon observational and modeling analyses. From the observational analyses, this sea fog event is a typical adv...In this paper, a heavy sea fog event occurring over the Yellow Sea on 11 April 2004 was investigated based upon observational and modeling analyses. From the observational analyses, this sea fog event is a typical advection cooling case. Sea surface temperature(SST) and specific humidity(SH) show strong gradients from south to north, in which warm water is located in the south and consequently, moisture is larger in the south than in the north due to evaporation processes. After fog formation, evaporation process provides more moisture into the air and further contributes to fog evolution. The sea fog event was reproduced by the Regional Atmospheric Modeling System(RAMS) reasonably. The roles of important physical processes such as radiation, turbulence as well as atmospheric stratification in sea fog's structure and its formation mechanisms were analyzed using the model results. The roles of long wave radiation cooling, turbulence as well as atmospheric stratification were analyzed based on the modeling results. It is found that the long wave radiative cooling at the fog top plays an important role in cooling down the fog layer through turbulence mixing. The fog top cooling can overpower warming from the surface. Sea fog develops upward with the aid of turbulence. The buoyancy term, i.e., the unstable layer, contributes to the generation of TKE in the fog region. However, the temperature inversion layer prevents fog from growing upward.展开更多
Clean Development Mechanism (CDM) has given birth to an international carbon trading market prosperity, which provides developing countries with valuable opportunity to address climate change issues right along with e...Clean Development Mechanism (CDM) has given birth to an international carbon trading market prosperity, which provides developing countries with valuable opportunity to address climate change issues right along with economic development and environmental improvement to achieve sustainable development. However, most studies of CDM focus on economics, and few on its legal problems. CDM involves too many aspects. And the clear legal attribute of trading object is the basis of progress of the transaction and also the start point of legal protection. Therefore, this paper in accordance with the inherent principle of property rights economics, and environmental economics in CDM, only discusses CDM carbon emission right legal interpretation and its attribution. The paper recommends that in order to ensure and promote the carbon emission right trading, carbon emission right should be attributed into the system of real rights to be regulated by Real Right Law. In this way, carbon emission right can gain exclusive power of possession and use, which can achieve a clear right def inition of environmental goods in line with Coase's theory to protect Chinese prof it in carbon trading market and promote the development of the carbon trading market further.展开更多
Postoperative adhesion(POA)widely occurs in soft tissues and usually leads to chronic pain,dysfunction of adjacent organs and some acute complications,seriously reducing patients’quality of life and even being life-t...Postoperative adhesion(POA)widely occurs in soft tissues and usually leads to chronic pain,dysfunction of adjacent organs and some acute complications,seriously reducing patients’quality of life and even being life-threatening.Except for adhesiolysis,there are few effective methods to release existing adhesion.However,it requires a second operation and inpatient care and usually triggers recurrent adhesion in a great incidence.Hence,preventing POA formation has been regarded as the most effective clinical strategy.Biomaterials have attracted great attention in preventing POA because they can act as both barriers and drug carriers.Nevertheless,even though much reported research has been demonstrated their efficacy on POA inhibition to a certain extent,thoroughly preventing POA formation is still challenging.Meanwhile,most biomaterials for POA prevention were designed based on limited experiences,not a solid theoretical basis,showing blindness.Hence,we aimed to provide guidance for designing anti-adhesion materials applied in different soft tissues based on the mechanisms of POA occurrence and development.We first classified the postoperative adhesions into four categories according to the different components of diverse adhesion tissues,and named them as“membranous adhesion”,“vascular adhesion”,“adhesive adhesion”and“scarred adhesion”,respectively.Then,the process of the occurrence and development of POA were analyzed,and the main influencing factors in different stages were clarified.Further,we proposed seven strategies for POA prevention by using biomaterials according to these influencing factors.Meanwhile,the relevant practices were summarized according to the corresponding strategies and the future perspectives were analyzed.展开更多
A generation planning model of six main power grids in China is developed to evaluate the potential of advanced power generation technologies into the Chinese power system as CDM (clean development mechanism). It is...A generation planning model of six main power grids in China is developed to evaluate the potential of advanced power generation technologies into the Chinese power system as CDM (clean development mechanism). It is investigated how delivered coal price, on-grid power price, and environmental protection may influence the potential of advanced thermal power generation as CDM projects. One finding from the baseline analysis is that coal price, on-grid power price, and environmental protection policy have only a small significance to the grid-wide specific CO2 emissions of thermal power generation up to the year 2026, while the best thermal generation mix is influenced largely by environmental protection policy. And it is found that not only the price of CER (certified emission reduction) and the length of crediting period but also on-grid power price and the reduction of air pollutants in the baseline have a significant influence on the potential of the CDM activities.展开更多
Since the Clean Development Mechanism(CDM) under the Kyoto Protocol was initiated,China and India have overwhelmingly led other developing countries regarding CDM projects development.A comparative study of the CDM in...Since the Clean Development Mechanism(CDM) under the Kyoto Protocol was initiated,China and India have overwhelmingly led other developing countries regarding CDM projects development.A comparative study of the CDM in India and China is conducted as there are many similarities between both India and China with regard to the CDM implementation due to the fact that India is another major developing country with a large population and a potential source of GHG emissions rivaling China in the near future.Through examining the development of and legal issues for CDM projects in India,its experience and lessons regarding developing and managing CDM projects that China can critically learn are discussed.展开更多
This paper shall show an economic feasible approach to implement greenhouse gas(GHG) reduction measures into steel companies. The goal to improve energy consumption is directly linked to the reduction of GHG emissions...This paper shall show an economic feasible approach to implement greenhouse gas(GHG) reduction measures into steel companies. The goal to improve energy consumption is directly linked to the reduction of GHG emissions and therefore directly in correlation with the economic viability. A baseline scenario of the considered reference system and of the respective reference year has to be defined, mapped and analysed. In a second step an analysis of the same operation using available and prospected best available technology (BAT) processes is carried out to generate a basis for a benchmark system. The identified reduction potentials are reported and the GHG emission reductions are put into relation to the investment cost of the new process technologies/process adaption to be implemented.This economic feasibility calculation is necessary to realise a cost efficient GHG reduction roadmap implementation into the company's business operations. The GHG reduction roadmap is developed using the abatement curve concept to get an indication of ' low hanging fruits' and for establishing a sequence for implementing carbon emission reductions measures. The scope of that approach can be extended by including further important environmental parameters like NOx, SO_2,CO,dust,heavy metal emissions in air as well as production residues.That gives in the end a broader picture and more starting points to improve the overall environmental performance of steel producing companies beyond the GHG emissions and energy consumption.展开更多
Clean Development Mechanism (CDM) has given birth to an international carbon trading market prosperity,which provides developing countries with valuable opportunities to address climate change issues together with eco...Clean Development Mechanism (CDM) has given birth to an international carbon trading market prosperity,which provides developing countries with valuable opportunities to address climate change issues together with economic development and environmental improvement to achieve the sustainable goal. China,as the biggest carbon market,has caught worldwide attention. However,most studies of CDM focus on economics and environmental science,few on its legal problems. Transaction activities are the essence of market mechanism. To protect the benefits of market participators and regulate the market orders,the Contract Law takes this important role along with development of market mechanism. Therefore,this paper only focuses on the carbon market in China,with the assessment of the risks in the CDM development first. The involved contracts will be identified and analyzed to point out the major contract legal issues in Chinese carbon market. In the meantime,this paper further discusses that measurements at both private level and governmental level should be taken to protect and realize the utility and equality of contract in the carbon market.展开更多
CDM will reduce the global GHG emissions with lower costs while promoting sustainable development of the developing countries.However,the lack of distribution equilibrium has been a problem not solved for a long time....CDM will reduce the global GHG emissions with lower costs while promoting sustainable development of the developing countries.However,the lack of distribution equilibrium has been a problem not solved for a long time.In order to increase CDM distribution equilibrium in China,CDM support requirement extent of different areas is analyzed based on the study on the economic development and sustainable development capability.At the same time,registered and issued projects are analyzed to have an assessment on the CDM distribution equilibrium in China.Based on the study,it is concluded that there is a lack of CDM distribution equilibrium in China as most of CDM support has gone to the relatively more developed areas.Based on the reason analysis from the sector development,CDM market and information circulation aspects,suggestions are given to support CDM development in western areas by the"sector development guidance+CDM capability construction+market support"mode in this paper.展开更多
基金National Natural Science Foundation of China(41975073,42274215)Wuxi University Research Start-up Fund for Introduced Talents (2023r037)+1 种基金Qinglan Project of Jiangsu Province for DING Liu-guan"333"Project of Jiangsu Province for DING Liu-guan
文摘The Northeastern China cold vortex(NCCV)is one type of strong cyclonic vortex that occurs near Northeastern China(NEC),and NCCV activities are typically accompanied by a series of hazardous weather.This paper employed an automatic algorithm to identify the NCCVs from 1979 to 2018 and analyzed their circulation patterns and climatic impacts by using the defined NCCV intensity index(NCCVI).The analysis revealed that the NCCV activities in summer exhibited a strong inter-annual variability,with an obvious periodicity of 3-4 years and 6-7 years,but without significant trends.In years when the NCCVI was high,NEC experienced negative geopotential height anomalies,cyclonic circulation,and cooler temperature anomalies,which were conducive to the maintenance and development of NCCV activities.Furthermore,large amounts of water vapor converged in NEC through two transportation routes as the NCCVs intensified,leading to a significant positive(negative)correlation with the summer precipitation(surface temperature)in NEC.The Atlantic sea surface temperature(SST)anomalies were closely related to summer NCCV activities.As the Atlantic SST rose,large amounts of surface sensible and latent heat flux were transported into the lower troposphere,inducing a positive geopotential height anomaly that occurred on the east side of the heat source.As a result,an eastward diverging flow was formed in the upper troposphere and propagated downstream,i.e.,the eastward propagating Rossby wave train,which eventually led to a coupled circulation in the Ural Mountains and NEC,as well as more intensive NCCV activities in summer.
文摘The increase of atmospheric carbon dioxide and the global warming due to its greenhouse effect resulted in worldwide concerns. On the other hand, carbon dioxide might be considered as a valuable and renewable carbon source. One approach to reduce carbon dioxide emissions could be its capture and recycle via transformation into chemicals using the technologies in C1 chemistry. Despite its great interest, there are difficulties in CO2 separation on the one hand, and thermodynamic stability of carbon dioxide molecule rendering its chemical activity low on the other hand. Carbon dioxide has been already used in petrochemical industries for production of limited chemicals such as urea. The utilization of carbon dioxide does not necessarily involve development of new processes, and in certain processes such as methanol synthesis and methane steam reforming, addition of CO2 into the feed results in its utilization and increases carbon efficiency. In other cases, modifications in catalyst and/or processes, or even new catalysts and processes, are necessary. In either case, catalysis plays a crucial role in carbon dioxide conversion and effective catalysts are required for commercial realization of the related processes. Technologies for CO2 utilization are emerging after many years of research and development efforts.
基金supported in parts by grants from the Disciplinary Group of Psychology and Neuroscience Xinxiang Medical University,China(2016PN-KFKT-06)Department of Education of Henan Province,China(16IRTSTHN020)+1 种基金the National Natural Science Foundation of China(31471118)UK Alzheimer’s Research Trust(ART/PPG2009A/2)
文摘Alzheimer’s disease (AD) is an age-related eurodegenerative disease that represents the most common cause of dementia among the elderly people. With the increasingly aging population, AD has presented an overwhelming healthcare challenge to modern society; the World Alzheimer Report 2015 has estimated that 46.8 million people worldwide lived with dementia in 2015 and this number will rise to 74.7 million in 2030 and that the total cost of dementia was 818 billion in US$ in 2015 and will reach two trillion in 2030. Post-mortem studies have identified two histopathological hallmarks in the brains of AD patients; extracellular senile plaque with elevated deposition of amyloid β (Aβ) peptides, and intracellular neurofibrillary tangle composed of hyper-phosphorylated microtubule-associated protein tau.Etiologically, progressive neuronal loss within the cerebral cortex and hippocampus regions of the brain leads to irreversible decline in, and eventually complete loss of, memory and other cognitive functions that afflict AD patients. The widely-accepted amyloid cascade hypothesis for AD pathogenesis holds that accumulation and aggregation of neurotoxic Aβ peptides, due to imbalance of their generation and clearance as a result of changes in genetic makeup, aging and/or exposure to environmental risk factors, is a major and early trigger of AD. This hypothesis has continuously gained support by preclinical and clinical studies (Selkoe and Hardy, 2016). However, the intensive and costly drug discovery efforts over the past decades based on such a hypothesis have proved extremely frustrating in developing effective therapeutics to treat or slow down the progress of AD, highlighting the need for more research to improve our understanding towards the cellular and molecular mechanisms by which Aβ peptides bring about neurotoxicity and cognitive dysfunction.
文摘China is now facing huge pressure from both the domestic concern of energy security and the global community's call for emission reduction commitment.As one of the major energy consumers and greenhouse gas emitters,China's iron and steel industry has a huge clean development mechanism(CDM) potential.This article both quantitatively and qualitatively analyzes the current status of CDM project activities in the iron and steel industry in China,including characteristics of approved project types,applicable methodologies,and potential technology fields.From the perspective of project implementation,the article summarizes development barriers such as high investment risk,difficulty in project identification,strict requirements on PPDs,long registration waiting time,and etc.Policy suggestions are also put forwarded to help better promote the development of CDM projects in the iron and steel industry.
文摘The Clean Development Mechanism,a flexibility mechanism contained in the KyotoProtocol, offers China an important tool to attractinvestment in clean energy technology and processesinto its electricity sector. The Chinese electricitysector places centrally in the country’s economy andenvironment, being a significant contributor to theacid rain and air pollution problems that plague manyof China’s cities and regions, and therefore a focusof many related energy and environmental policies.China’s electricity sector has also been the subjectof a number of economic analyses that have showedthat it contains the highest potential for clean energyinvestment through the Clean DevelopmentMechanism of any economic sector in China. Thismechanism, through the active participation frominvestors in more industrialized countries, can helpalleviate the environmental problems attributable toelectricity generation in China through advancingsuch technology as wind electricity generation, cleancoal technology, high efficient natural gas electricitygeneration, or utilization of coal mine methane. Inthis context, the Clean Development Mechanismalso compliments a range of environmental and energypolicies which are strategizing to encourage thesustainable development of China’s economy.
文摘There are abundant energy reserves such as oil,natural gas,hydrate,and wind energy in the ocean.Countries around the globe are competing to advance their marine energy development technologies.The exploitation of marine resources relies on cutting-edge industrial equipment.After decades of R&D endeavors,China has obtained most of the key technologies for the design,production,testing,and field application of marine energy development equipment(Xie and Zeng,2021).
文摘This paper presents a three-stage hypothesis on the development of creative industrial clusters, which includes stages of agglomeration, interfacing, and network development. In the first stage, micro-entities concentrate geographically in a creative industrial cluster in search of resources. The second stage reflects the need for building identity. Finally, the third stage is the outcome of multi-dimensional expansion. As a creative industrial cluster develops, its focus moves from geographic concentration to division of labor and the creation of novel systems. Using this three-stage framework, this paper conducts an empirical study on Beijing's 798 District ("798"). Our study finds that the "self-destruction "phenomenon (which appeared after 798 had reached the stage of network development in a low-level capacity) is essentially the product of a squeezing effect of commercial prosperity on art production. Our study further examines four models of art-commerce integration and explains the ways in which creative industrial clusters are different from conventional industrial clusters: a creative cluster is a platform of integration for culture, commerce, and technology. Its course of development is characterized by novelty, emergence of identity through interfacing, and network cooperation.
文摘This paper summarizes the results of the implementation of the CDM in Argentina during the first period of commitment of the Kyoto Protocol. From a total of sixty- five projects ideas, forty-four achieved registration under the CDM EB while the rest remained approved at national level (12), under evaluation (2), suspended (5) or rejected (2). Most of the projects focused on the generation of electricity from renewable energy, mainly wind energy and the use of landfill gas and methane for energy. Emissions reductions achieved 33.4% of the expected CERs up to 2012 with strong differences among sectors. Results demonstrated that under the current Argentina’s energy policy framework, the income by the selling of CERs covered less than 6% of the incremental costs for renewable energy projects. A sensitivity analysis to evaluate the impact of CDM in the coverage of incremental costs for renewable energy based on the prices of both the energy in the local market and the CER demonstrated that the best conditions would only cover 15% of those costs. The contribution of CDM to technology transfer in Argentina was minor considering that 45% of the projects qualified as type III where technological learning and capacity building were limited at the level of operation and maintenance of a foreign technology. Domestic and external barriers that prevented a better performance of CDM projects in terms of GHG mitigation, technology transfer and the contribution to a sustainable development were also analyzed.
文摘Since the launch of the economic reform and opening to the outside world, China has seen rapid growth in its export of mechanical and electrical products, with its export
基金supported by National Key Project of ScientificTechnical Supporting Programs Funded by Ministry of Science & Technology of China in the 11th Five-Year Plan (Grant No.2007BAC03A04)
文摘Global climate change has been identified as the first of the top ten environmental problems in the world. As climate change will have serious effects on the social and economic development and everyday, living of people in the world, many of the countries and governments are taking untiring efforts to combat climate change. As one of the important mechanisms of reducing greenhouse gas (GHG) emissions in the Kyoto Protocol, Clean Development Mechanism (CDM) has not only provided chance for developed countries to fulfill greenhouse emission reduction obligations, but also provided an opportunity for developing countries to combat climate change under the sustainable development frame. The dual objectives of developed countries' GHG emissions' reduction obligation achievement and developing cotmtries'sustainable development will be achieved under the CDM. As a country with responsibility; China has been positively developing CDM projects and promoting energy saving and emissions reduction during the three yeors after the Kyoto Protocol came into force, and CDM projects development has always been in the front tank in the world. However; as the vast clime within China, notable differences occur in different regions. In order to promote the CDM development in China, it is necessa^T to have regional CDM capability construction in accordance with the practicality in different regions. Based on the Slat Analysis of developed CDM projects and current CDM development status in China, problems in the CDM development of China, including the inefficiency in small and medium-sized CDM Projects' development, over centralization of CDM development scope and especially the differentiated provincial CDM projects developing capability are pointed out in the paper: What's more, reasons for the problems are analyzed from fire leading.factors, including policy orient, information asymmetry and weak CDM capability, In order to promote CDM projects development in China, a new CDM capability, construction model is put forward in the paper.
文摘Based on the status and characteristics of Clean Development Mechanism (CDM) renewable energy project and the mode of cyclic economy, aimed at achieving the maximum capacity of carbon sinks in the system, Lvjin Jiayuan—New Countryside Distripark CDM project in Wuchuan County was taken as an example for developing an interval linear programming (ILP) model to optimize the crops planting scheme and cows breeding scheme by using interval optimal method. The case showed that the optimized crops planting scheme and cows breeding scheme obtained from the optimal model was reasonable with relatively preferable overall performance. In the context of meeting economic benefits and fertilizer, electricity demand, [231 287.8, 273 312.7] t of CO2 could be absorbed and fixed, which had increased by [12.94, 33.46]% compared with the feasibility scheme of case project and provided technical support for making the decision in CDM project.
基金National Natural Science Foundation of China, No.40461002 The Key Project of the Ministry of Education, N0.205184
文摘Tamarix nabkha is one of the most widespread nabkhas, distributing in the arid region of China. Based on the observations outdoors and the simulation experiments in laboratories, analysis in this paper refers to the biological geomorphologic features and growth process of Tamarix nabkhas in the middle and lower reaches of the Hotan River, Xinjiang. And the results indicate that the ecological type of Tamarix in the study area is a kind of Tugaic soil habitat based on the deep soil of the Populus Diversifolia forests and shrubs. This type of habitat can be divided into three kinds of sub-habitats which demonstrate the features of ecological environment of Tamarix nabkhas during the differential developed phases. Meanwhile, the Tamar, ix nabkha can exert intensified disturbance current on wind-sand flow on the ground,and its root and stems not only have strong potential of sprouting but are characteristic of wind erosion-tolerance, resistance to be buried by sand and respectively tough rigid of the lignified branches, for it has a rather longer life-time. Thus, the wind speed profile influenced by the Tamarix nabkha is different from the Phragmites nabkha and Alhagi nabkha. And the structure of the wind flow is beneficial to aeolian sand accumulating in/around Tamarix shrub, which can create unique Tamarix nabkhas with higher average gradient and longer periodicity of life. Tamarix nabkha evolution in the area experienced three stages: growth stage, mature and steady stage and withering stage. In each stage, morphological features and geomorphic process of Tamarix nabkha are different due to the discrep- ant interaction between the nabkha and aeolian sand flow.
基金supported by the 201205010-5 program of the State Oceanic Administration of China and the Natural Science Foundation of China under the grant 41306028partly supported by the National Natural Science Foundation of China under the grant number, 406750060 and 41275049+5 种基金the Chinese Ministry of Science and Technology under the 863 Project grant number 2006 AA09Z151the Chinese Meteorological Administration under the grant number GYHY(QX)200706031the China Scholarship Council for the financial support to his study in NOAA from 2008 to 2010, which enables him to participate in the present worksupported by China postdoctoral funding under the grant 2012M511545the Natural Science Foundation of China under the grant 41305086supported by the open project of the Lab. of Physical Oceanography, Ocean University of China
文摘In this paper, a heavy sea fog event occurring over the Yellow Sea on 11 April 2004 was investigated based upon observational and modeling analyses. From the observational analyses, this sea fog event is a typical advection cooling case. Sea surface temperature(SST) and specific humidity(SH) show strong gradients from south to north, in which warm water is located in the south and consequently, moisture is larger in the south than in the north due to evaporation processes. After fog formation, evaporation process provides more moisture into the air and further contributes to fog evolution. The sea fog event was reproduced by the Regional Atmospheric Modeling System(RAMS) reasonably. The roles of important physical processes such as radiation, turbulence as well as atmospheric stratification in sea fog's structure and its formation mechanisms were analyzed using the model results. The roles of long wave radiation cooling, turbulence as well as atmospheric stratification were analyzed based on the modeling results. It is found that the long wave radiative cooling at the fog top plays an important role in cooling down the fog layer through turbulence mixing. The fog top cooling can overpower warming from the surface. Sea fog develops upward with the aid of turbulence. The buoyancy term, i.e., the unstable layer, contributes to the generation of TKE in the fog region. However, the temperature inversion layer prevents fog from growing upward.
基金supported by National Key Project of Scientific and Technical Supporting Programs Funded by Ministry of Science and Tech-nology of China in the 11th Five-Year Plan (Grant No. 2007BAC03A12).
文摘Clean Development Mechanism (CDM) has given birth to an international carbon trading market prosperity, which provides developing countries with valuable opportunity to address climate change issues right along with economic development and environmental improvement to achieve sustainable development. However, most studies of CDM focus on economics, and few on its legal problems. CDM involves too many aspects. And the clear legal attribute of trading object is the basis of progress of the transaction and also the start point of legal protection. Therefore, this paper in accordance with the inherent principle of property rights economics, and environmental economics in CDM, only discusses CDM carbon emission right legal interpretation and its attribution. The paper recommends that in order to ensure and promote the carbon emission right trading, carbon emission right should be attributed into the system of real rights to be regulated by Real Right Law. In this way, carbon emission right can gain exclusive power of possession and use, which can achieve a clear right def inition of environmental goods in line with Coase's theory to protect Chinese prof it in carbon trading market and promote the development of the carbon trading market further.
基金financial support from the National Natural Science Foundation of China(Nos.32171345,T2288101,U20A20390,and 11827803)Fok Ying Tung Education Foundation(No.141039)+1 种基金International Joint Research Center of Aerospace Biotechnology and Medical Engineering,Ministry of Science and Technology of China,the 111 Project(No.B13003)the Academic Excellence Foundation of BUAA for PhD Students.
文摘Postoperative adhesion(POA)widely occurs in soft tissues and usually leads to chronic pain,dysfunction of adjacent organs and some acute complications,seriously reducing patients’quality of life and even being life-threatening.Except for adhesiolysis,there are few effective methods to release existing adhesion.However,it requires a second operation and inpatient care and usually triggers recurrent adhesion in a great incidence.Hence,preventing POA formation has been regarded as the most effective clinical strategy.Biomaterials have attracted great attention in preventing POA because they can act as both barriers and drug carriers.Nevertheless,even though much reported research has been demonstrated their efficacy on POA inhibition to a certain extent,thoroughly preventing POA formation is still challenging.Meanwhile,most biomaterials for POA prevention were designed based on limited experiences,not a solid theoretical basis,showing blindness.Hence,we aimed to provide guidance for designing anti-adhesion materials applied in different soft tissues based on the mechanisms of POA occurrence and development.We first classified the postoperative adhesions into four categories according to the different components of diverse adhesion tissues,and named them as“membranous adhesion”,“vascular adhesion”,“adhesive adhesion”and“scarred adhesion”,respectively.Then,the process of the occurrence and development of POA were analyzed,and the main influencing factors in different stages were clarified.Further,we proposed seven strategies for POA prevention by using biomaterials according to these influencing factors.Meanwhile,the relevant practices were summarized according to the corresponding strategies and the future perspectives were analyzed.
文摘A generation planning model of six main power grids in China is developed to evaluate the potential of advanced power generation technologies into the Chinese power system as CDM (clean development mechanism). It is investigated how delivered coal price, on-grid power price, and environmental protection may influence the potential of advanced thermal power generation as CDM projects. One finding from the baseline analysis is that coal price, on-grid power price, and environmental protection policy have only a small significance to the grid-wide specific CO2 emissions of thermal power generation up to the year 2026, while the best thermal generation mix is influenced largely by environmental protection policy. And it is found that not only the price of CER (certified emission reduction) and the length of crediting period but also on-grid power price and the reduction of air pollutants in the baseline have a significant influence on the potential of the CDM activities.
基金supported by the MOE (Ministry of Education in China) Project of Humanities and Social Sciences (Project No.11YJC820045)
文摘Since the Clean Development Mechanism(CDM) under the Kyoto Protocol was initiated,China and India have overwhelmingly led other developing countries regarding CDM projects development.A comparative study of the CDM in India and China is conducted as there are many similarities between both India and China with regard to the CDM implementation due to the fact that India is another major developing country with a large population and a potential source of GHG emissions rivaling China in the near future.Through examining the development of and legal issues for CDM projects in India,its experience and lessons regarding developing and managing CDM projects that China can critically learn are discussed.
文摘This paper shall show an economic feasible approach to implement greenhouse gas(GHG) reduction measures into steel companies. The goal to improve energy consumption is directly linked to the reduction of GHG emissions and therefore directly in correlation with the economic viability. A baseline scenario of the considered reference system and of the respective reference year has to be defined, mapped and analysed. In a second step an analysis of the same operation using available and prospected best available technology (BAT) processes is carried out to generate a basis for a benchmark system. The identified reduction potentials are reported and the GHG emission reductions are put into relation to the investment cost of the new process technologies/process adaption to be implemented.This economic feasibility calculation is necessary to realise a cost efficient GHG reduction roadmap implementation into the company's business operations. The GHG reduction roadmap is developed using the abatement curve concept to get an indication of ' low hanging fruits' and for establishing a sequence for implementing carbon emission reductions measures. The scope of that approach can be extended by including further important environmental parameters like NOx, SO_2,CO,dust,heavy metal emissions in air as well as production residues.That gives in the end a broader picture and more starting points to improve the overall environmental performance of steel producing companies beyond the GHG emissions and energy consumption.
基金supported by National Key Project of Scientific and Technical Supporting Programs Funded by Ministry of Science & Technology of China in the 11th Five-Year Plan (Grant No. 2007BAC03A12)
文摘Clean Development Mechanism (CDM) has given birth to an international carbon trading market prosperity,which provides developing countries with valuable opportunities to address climate change issues together with economic development and environmental improvement to achieve the sustainable goal. China,as the biggest carbon market,has caught worldwide attention. However,most studies of CDM focus on economics and environmental science,few on its legal problems. Transaction activities are the essence of market mechanism. To protect the benefits of market participators and regulate the market orders,the Contract Law takes this important role along with development of market mechanism. Therefore,this paper only focuses on the carbon market in China,with the assessment of the risks in the CDM development first. The involved contracts will be identified and analyzed to point out the major contract legal issues in Chinese carbon market. In the meantime,this paper further discusses that measurements at both private level and governmental level should be taken to protect and realize the utility and equality of contract in the carbon market.
基金supported by National Key Project of Scientific and Technical Supporting Programs Funded by Ministry of Science and Technology of China in the 11th Five-Year Plan (Grant No. 2007BAC03A04)
文摘CDM will reduce the global GHG emissions with lower costs while promoting sustainable development of the developing countries.However,the lack of distribution equilibrium has been a problem not solved for a long time.In order to increase CDM distribution equilibrium in China,CDM support requirement extent of different areas is analyzed based on the study on the economic development and sustainable development capability.At the same time,registered and issued projects are analyzed to have an assessment on the CDM distribution equilibrium in China.Based on the study,it is concluded that there is a lack of CDM distribution equilibrium in China as most of CDM support has gone to the relatively more developed areas.Based on the reason analysis from the sector development,CDM market and information circulation aspects,suggestions are given to support CDM development in western areas by the"sector development guidance+CDM capability construction+market support"mode in this paper.