Objective:To investigate the effect of locking compression plate internal fixation on the injury extent and bone metabolism of Robinson 2A and 2B middle clavicular fractures.Methods:Totally 80 cases of patients with R...Objective:To investigate the effect of locking compression plate internal fixation on the injury extent and bone metabolism of Robinson 2A and 2B middle clavicular fractures.Methods:Totally 80 cases of patients with Robinson 2A and 2B middle clavicular fractures admitted to our hospital between March 2017 and January 2019 were divided into the control group(n=41)receiving conventional kirschner wire internal fixation and the observation group(n=39)receiving locking compression plate internal fixation according to the operation plans.The differences in serum contents of inflammatory factors,oxidative stress indexes and bone metabolism indexes were compared between the two groups of patients before patients entered operating room,24 h after surgery and 48 h after surgery.Results:Before patients entered operating room,there were no statistically significant differences in the serum contents of inflammatory factors,oxidative stress indexes or bone metabolism indexes between the two groups(P>0.05).At 24 h and 48 h after surgery,serum inflammatory factors interleukin-1(IL-1),interleukin-17(IL-17),high-sensitivity C-reactive protein(hs-CRP)and tumor necrosis factorα(TNF-α)contents in the observation group were lower than those in the control group;serum reactive oxygen species(ROS)and lipid hydroperoxide(LHP)contents were lower than those in the control group,while catalase(CAT)and glutathione peroxidase(GSH-Px)contents were higher than those in the control group;serum N-terminal propeptide of procollagen type I(PINP),bone gla protein(BGP)and alkaline phosphatase(ALP)contents were higher than those in the control group,while N-telopeptide of typeⅠcollagen(NTX),C-telopeptide of typeⅠcollagen(CTX)and tartrate-resistant acid phosphatase 5b(TRACP5b)contents were lower than those in the control group(P<0.05).Conclusion:Locking compression plate internal fixation can reduce the postoperative trauma extent and help promote the fracture healing in patients with Robinson 2A and 2B middle clavicular fracture.展开更多
Objective:To compare the effect of locking compression plate internal fixation and reconstruction plate fixation for the treatment of mid-shaft clavicular fracture.Methods: In this study, the medical records of 68 pat...Objective:To compare the effect of locking compression plate internal fixation and reconstruction plate fixation for the treatment of mid-shaft clavicular fracture.Methods: In this study, the medical records of 68 patients with mid-shaft clavicular fractures treated in our department from May 2014 to May 2017 were retrospectively analyzed. 32 patients in the control group received the reconstruction plate fixation, while 36 patients in the observation group received the locking compression plate internal fixation. Patients were followed up for 12 months, thereafter, various indicators including operative indexes, Constant-Murley (CM) score, disability of arm shoulder and hand (DASH) score, activities of daily living (ADL), and complications were compared between groups.Results: The incision length, intraoperative blood loss, operation time, and fracture healing time of the observation group were significantly lower than the control group (P<0.05). The postoperative CM scores of the two groups were significantly increased, moreover, the scores of muscle strength, daily life and activity were significantly in the observation group were higher than those of the control group (P<0.05), and no difference was found in the pain degree (P>0.05). There was a decrease trend in the DASH score and an increase trend in the ADL score in both groups, while both indexes were better in the observation group than in the control group (P<0.05). The total incidence of complications in the observation group was significantly lower than that in the control group (8.33% vs 18.75%,P<0.05).Conclusion: Compared with the reconstruction plate fixation, locking compression plate internal fixation has the advantages of more mini invasive, better amelioration of shoulder joint function and less complication for patients with mid-shaft clavicular fractures.展开更多
基金Application and clinical characteristics of Ilizarov technique in the treatment of bone defect,No:20150802.
文摘Objective:To investigate the effect of locking compression plate internal fixation on the injury extent and bone metabolism of Robinson 2A and 2B middle clavicular fractures.Methods:Totally 80 cases of patients with Robinson 2A and 2B middle clavicular fractures admitted to our hospital between March 2017 and January 2019 were divided into the control group(n=41)receiving conventional kirschner wire internal fixation and the observation group(n=39)receiving locking compression plate internal fixation according to the operation plans.The differences in serum contents of inflammatory factors,oxidative stress indexes and bone metabolism indexes were compared between the two groups of patients before patients entered operating room,24 h after surgery and 48 h after surgery.Results:Before patients entered operating room,there were no statistically significant differences in the serum contents of inflammatory factors,oxidative stress indexes or bone metabolism indexes between the two groups(P>0.05).At 24 h and 48 h after surgery,serum inflammatory factors interleukin-1(IL-1),interleukin-17(IL-17),high-sensitivity C-reactive protein(hs-CRP)and tumor necrosis factorα(TNF-α)contents in the observation group were lower than those in the control group;serum reactive oxygen species(ROS)and lipid hydroperoxide(LHP)contents were lower than those in the control group,while catalase(CAT)and glutathione peroxidase(GSH-Px)contents were higher than those in the control group;serum N-terminal propeptide of procollagen type I(PINP),bone gla protein(BGP)and alkaline phosphatase(ALP)contents were higher than those in the control group,while N-telopeptide of typeⅠcollagen(NTX),C-telopeptide of typeⅠcollagen(CTX)and tartrate-resistant acid phosphatase 5b(TRACP5b)contents were lower than those in the control group(P<0.05).Conclusion:Locking compression plate internal fixation can reduce the postoperative trauma extent and help promote the fracture healing in patients with Robinson 2A and 2B middle clavicular fracture.
文摘Objective:To compare the effect of locking compression plate internal fixation and reconstruction plate fixation for the treatment of mid-shaft clavicular fracture.Methods: In this study, the medical records of 68 patients with mid-shaft clavicular fractures treated in our department from May 2014 to May 2017 were retrospectively analyzed. 32 patients in the control group received the reconstruction plate fixation, while 36 patients in the observation group received the locking compression plate internal fixation. Patients were followed up for 12 months, thereafter, various indicators including operative indexes, Constant-Murley (CM) score, disability of arm shoulder and hand (DASH) score, activities of daily living (ADL), and complications were compared between groups.Results: The incision length, intraoperative blood loss, operation time, and fracture healing time of the observation group were significantly lower than the control group (P<0.05). The postoperative CM scores of the two groups were significantly increased, moreover, the scores of muscle strength, daily life and activity were significantly in the observation group were higher than those of the control group (P<0.05), and no difference was found in the pain degree (P>0.05). There was a decrease trend in the DASH score and an increase trend in the ADL score in both groups, while both indexes were better in the observation group than in the control group (P<0.05). The total incidence of complications in the observation group was significantly lower than that in the control group (8.33% vs 18.75%,P<0.05).Conclusion: Compared with the reconstruction plate fixation, locking compression plate internal fixation has the advantages of more mini invasive, better amelioration of shoulder joint function and less complication for patients with mid-shaft clavicular fractures.
