Medically, electrical impedance tomography （EIT） is a relatively inexpensive, safe, non-invasive and portable technique compared with computerized tomography （CT） and magnetic resonance imaging （MRI）. In this pa...Medically, electrical impedance tomography （EIT） is a relatively inexpensive, safe, non-invasive and portable technique compared with computerized tomography （CT） and magnetic resonance imaging （MRI）. In this paper, EIT_TJU_ II system is developed including both the data collection system and image reconstruction algo- rithm. The testing approach of the system performance, including spatial resolution and sensitivity, is described through brine tank experiments. The images of the thorax physical model verify that the system can reconstruct the interior resistivity distribution. Finally, the lung ventilation functional monitoring in vivo is realized by EIT, and the visualized images indicate that the configuration and performance of EIT_TJU_ II system are feasible and EIT is a promising technique in clinical monitoring application.展开更多
Novel advances in the field of brain imaging have enabled the unprecedented clinical application of various imaging modalities to facilitate disease diagnosis and treatment. Electrical impedance tomography(EIT) is a f...Novel advances in the field of brain imaging have enabled the unprecedented clinical application of various imaging modalities to facilitate disease diagnosis and treatment. Electrical impedance tomography(EIT) is a functional imaging technique that measures the transfer impedances between electrodes on the body surface to estimate the spatial distribution of electrical properties of tissues. EIT offers many advantages over other neuroimaging technologies,which has led to its potential clinical use. This qualitative review provides an overview of the basic principles,algorithms, and system composition of EIT. Recent advances in the field of EIT are discussed in the context of epilepsy,stroke, brain injuries and edema, and other brain diseases. Further, we summarize factors limiting the development of brain EIT and highlight prospects for the field. In epilepsy imaging, there have been advances in EIT imaging depth,from cortical to subcortical regions. In stroke research, a bedside EIT stroke monitoring system has been developed for clinical practice, and data support the role of EIT in multi-modal imaging for diagnosing stroke. Additionally, EIT has been applied to monitor the changes in brain water content associated with cerebral edema, enabling the early identification of brain edema and the evaluation of mannitol dehydration. However, anatomically realistic geometry,inhomogeneity, cranium completeness, anisotropy and skull type, etc., must be considered to improve the accuracy of EIT modeling. Thus, the further establishment of EIT as a mature and routine diagnostic technique will necessitate the accumulation of more supporting evidence.展开更多
This paper presents different views on electrode modelling, which include electrode electrochemistry models for modelling the effects of electrode-electrolyte interface, electric field electrode models for modelling e...This paper presents different views on electrode modelling, which include electrode electrochemistry models for modelling the effects of electrode-electrolyte interface, electric field electrode models for modelling electrode geometry, and electrode models for modelling the effects of electrode common mode voltage and double layer capacitance. Taking the full electrode models into consideration in electrical impedance tomography (EIT) will greatly help the optimised approach to a good solution and further understanding of the measurement principle.展开更多
In electrical impedance tomography (EIT) an approximation for the internal resistivity distribution is computed based on the knowledge of the injected currents and measured voltages on the surface of the body. Several...In electrical impedance tomography (EIT) an approximation for the internal resistivity distribution is computed based on the knowledge of the injected currents and measured voltages on the surface of the body. Several difficulties have been identified in EIT, where the main problem is the low spatial resolution. This paper presents a fining mesh method based on finite element method (FEM), by fining the sensitive element, the most actual signal is obtained in certain electrode number. Newton-Raphson reconstruction algorithm improves the spatial solution of image. The advantages of this method are the improvement of spatial resolution and ease of implementation.展开更多
Solution to impedance distribution in electrical impedance tomography （EIT） is an ill-posed nonlinear inverse problem. It is especially difficult to reconstruct an EIT image in the center area of a measured object. ...Solution to impedance distribution in electrical impedance tomography （EIT） is an ill-posed nonlinear inverse problem. It is especially difficult to reconstruct an EIT image in the center area of a measured object. Tikhonov regularization with some prior information is a sound regnlarization method for static electrical impedance tomography under the condition that some true impedance distribution information is known a priori. This paper presents a direct search method （DSM） as pretreatment of image reconstruction through which one not only can construct a regularization matrix which may locate in areas of impedance change, but also can obtain an initial impedance distribution more similar to the true impedance distribution, as well as better current modes which can better distinguish the initial distribution and the true distribution. Simulation results indicate that, by using DSM, resolution in the center area of the measured object can be improved significantly.展开更多
Electrical impedance tomography (EIT) is a technique for determining the electrical conductivity and permittivity distribution inside a medium from measurements made on its surface. The impedance distribution reconstr...Electrical impedance tomography (EIT) is a technique for determining the electrical conductivity and permittivity distribution inside a medium from measurements made on its surface. The impedance distribution reconstruction in EIT is a nonlinear inverse problem that requires the use of a regularization method. The generalized Tikhonov regularization methods are often used in solving inverse problems. However, for EIT image reconstruction, the generalized Tikhonov regularization methods may lose the boundary information due to its smoothing operation. In this paper, we propose an iterative Lavrentiev regularization and L-curve-based algorithm to reconstruct EIT images. The regularization parameter should be carefully chosen, but it is often heuristically selected in the conventional regularization-based reconstruction algorithms. So, an L-curve-based optimization algorithm is used for selecting the Lavrentiev regularization parameter. Numerical analysis and simulation results are performed to illustrate EIT image reconstruction. It is shown that choosing the appropriate regularization parameter plays an important role in reconstructing EIT images.展开更多
Electrical Impedance Tomography(EIT)as a non-invasive of electrical conductivity imaging method commonly employs the stationary-coefficient based filters(such as FFT)in order to remove the noise signal.In the practica...Electrical Impedance Tomography(EIT)as a non-invasive of electrical conductivity imaging method commonly employs the stationary-coefficient based filters(such as FFT)in order to remove the noise signal.In the practical applications,the stationary-coefficient based filters fail to remove the time-varying random noise which leads to the lack of impedance measurement sensitivity.In this paper,the implementation of adaptive noise cancellation(ANC)algorithms which are Least Mean Square(LMS)and Normalized Least Mean Square(NLMS)filters onto Field Programmable Gate Array(FPGA)-based EIT system is proposed in order to eliminate the time-varying random noise signal.The proposed method was evaluated through experimental studies with biomaterial phantom.The reconstructed EIT images with NLMS is better than the images with LMS by amplitude response AR=12.5%,position error PE=200%,resolution RES=33%,and shape deformation SD=66%.Moreover,the Analog-to-Digital Converter(ADC)performances of power spectral density(PSD)and the effective number of bit ENOB with NLMS is higher than the performances with LMS by SI=5.7%and ENOB=15.4%.The results showed that implementing ANC algorithms onto FPGA-based EIT system shows significantly more accurate image reconstruction as compared without ANC algorithms implementation.展开更多
基金Supported by National Natural Science Foundation of China (No.60820106002, No.60532020)Tianjin Natural Science Foundation (No.08JCYBJC03500).
文摘Medically, electrical impedance tomography （EIT） is a relatively inexpensive, safe, non-invasive and portable technique compared with computerized tomography （CT） and magnetic resonance imaging （MRI）. In this paper, EIT_TJU_ II system is developed including both the data collection system and image reconstruction algo- rithm. The testing approach of the system performance, including spatial resolution and sensitivity, is described through brine tank experiments. The images of the thorax physical model verify that the system can reconstruct the interior resistivity distribution. Finally, the lung ventilation functional monitoring in vivo is realized by EIT, and the visualized images indicate that the configuration and performance of EIT_TJU_ II system are feasible and EIT is a promising technique in clinical monitoring application.
基金supported by the National Natural Science Foundation of China (81773353)Jilin Scientific and Technological Development Program (20200404148YY, 20200601005JC, 20210101317JC)+2 种基金Jilin Province Special Projec t of Medical and Health Talents (JLSCZD2019-032)the Research Funding Program of Norman Bethune Biomedical Engineering Center (BQEGCZX2019025)National College Students Innovation and Entrepreneurship Training Program (CN)(202010183691)。
文摘Novel advances in the field of brain imaging have enabled the unprecedented clinical application of various imaging modalities to facilitate disease diagnosis and treatment. Electrical impedance tomography(EIT) is a functional imaging technique that measures the transfer impedances between electrodes on the body surface to estimate the spatial distribution of electrical properties of tissues. EIT offers many advantages over other neuroimaging technologies,which has led to its potential clinical use. This qualitative review provides an overview of the basic principles,algorithms, and system composition of EIT. Recent advances in the field of EIT are discussed in the context of epilepsy,stroke, brain injuries and edema, and other brain diseases. Further, we summarize factors limiting the development of brain EIT and highlight prospects for the field. In epilepsy imaging, there have been advances in EIT imaging depth,from cortical to subcortical regions. In stroke research, a bedside EIT stroke monitoring system has been developed for clinical practice, and data support the role of EIT in multi-modal imaging for diagnosing stroke. Additionally, EIT has been applied to monitor the changes in brain water content associated with cerebral edema, enabling the early identification of brain edema and the evaluation of mannitol dehydration. However, anatomically realistic geometry,inhomogeneity, cranium completeness, anisotropy and skull type, etc., must be considered to improve the accuracy of EIT modeling. Thus, the further establishment of EIT as a mature and routine diagnostic technique will necessitate the accumulation of more supporting evidence.
文摘This paper presents different views on electrode modelling, which include electrode electrochemistry models for modelling the effects of electrode-electrolyte interface, electric field electrode models for modelling electrode geometry, and electrode models for modelling the effects of electrode common mode voltage and double layer capacitance. Taking the full electrode models into consideration in electrical impedance tomography (EIT) will greatly help the optimised approach to a good solution and further understanding of the measurement principle.
文摘In electrical impedance tomography (EIT) an approximation for the internal resistivity distribution is computed based on the knowledge of the injected currents and measured voltages on the surface of the body. Several difficulties have been identified in EIT, where the main problem is the low spatial resolution. This paper presents a fining mesh method based on finite element method (FEM), by fining the sensitive element, the most actual signal is obtained in certain electrode number. Newton-Raphson reconstruction algorithm improves the spatial solution of image. The advantages of this method are the improvement of spatial resolution and ease of implementation.
文摘Solution to impedance distribution in electrical impedance tomography （EIT） is an ill-posed nonlinear inverse problem. It is especially difficult to reconstruct an EIT image in the center area of a measured object. Tikhonov regularization with some prior information is a sound regnlarization method for static electrical impedance tomography under the condition that some true impedance distribution information is known a priori. This paper presents a direct search method （DSM） as pretreatment of image reconstruction through which one not only can construct a regularization matrix which may locate in areas of impedance change, but also can obtain an initial impedance distribution more similar to the true impedance distribution, as well as better current modes which can better distinguish the initial distribution and the true distribution. Simulation results indicate that, by using DSM, resolution in the center area of the measured object can be improved significantly.
文摘Electrical impedance tomography (EIT) is a technique for determining the electrical conductivity and permittivity distribution inside a medium from measurements made on its surface. The impedance distribution reconstruction in EIT is a nonlinear inverse problem that requires the use of a regularization method. The generalized Tikhonov regularization methods are often used in solving inverse problems. However, for EIT image reconstruction, the generalized Tikhonov regularization methods may lose the boundary information due to its smoothing operation. In this paper, we propose an iterative Lavrentiev regularization and L-curve-based algorithm to reconstruct EIT images. The regularization parameter should be carefully chosen, but it is often heuristically selected in the conventional regularization-based reconstruction algorithms. So, an L-curve-based optimization algorithm is used for selecting the Lavrentiev regularization parameter. Numerical analysis and simulation results are performed to illustrate EIT image reconstruction. It is shown that choosing the appropriate regularization parameter plays an important role in reconstructing EIT images.
基金he International Research Fellow of Japan Society for the Promotion of Science(Graduate School of Science and Engineering,Chiba University)and JSPS KAKENHI Grant Number JP18F18060.
文摘Electrical Impedance Tomography(EIT)as a non-invasive of electrical conductivity imaging method commonly employs the stationary-coefficient based filters(such as FFT)in order to remove the noise signal.In the practical applications,the stationary-coefficient based filters fail to remove the time-varying random noise which leads to the lack of impedance measurement sensitivity.In this paper,the implementation of adaptive noise cancellation(ANC)algorithms which are Least Mean Square(LMS)and Normalized Least Mean Square(NLMS)filters onto Field Programmable Gate Array(FPGA)-based EIT system is proposed in order to eliminate the time-varying random noise signal.The proposed method was evaluated through experimental studies with biomaterial phantom.The reconstructed EIT images with NLMS is better than the images with LMS by amplitude response AR=12.5%,position error PE=200%,resolution RES=33%,and shape deformation SD=66%.Moreover,the Analog-to-Digital Converter(ADC)performances of power spectral density(PSD)and the effective number of bit ENOB with NLMS is higher than the performances with LMS by SI=5.7%and ENOB=15.4%.The results showed that implementing ANC algorithms onto FPGA-based EIT system shows significantly more accurate image reconstruction as compared without ANC algorithms implementation.
文摘针对LSQR(least square QR-factorization)算法在求解电阻抗层析成像(electrical impedance tomography,EIT)逆问题时,由于矩阵维数高、计算量大而导致重建速度较慢的问题,提出基于小波多分辨分析的LSQR算法(wavelet multi-resolution based least square QR-factorization,WALSQR)。该方法将EIT的图像重建过程投影到低维的尺度空间进行,通过提取有效信息减少数据计算量,明显提高了图像重建速度。同时由于去除了噪声和冗余信息,保证了成像质量。本文将SALSQR方法分别应用于二维、三维EIT成像实验,证明其有效性,并为三维动态EIT图像重建算法的研究奠定了基础。
