Current Status of Forest Medicine Research in China

In recent years,due to regional pollution and deteriorating environment,combined with intense social competition and heavier life pressure,an increasing number of people are affected by lifestyle-related diseases and remain in a state of being sub-healthy.Therefore,health issue has been receiving unprecedented attention.

Traditional Chinese Medicine Playing a More Important Role in the World's Complementary Medicine Research——Minutes of the 3rd International Congress on Complementary Medicine Research

The 3rd International Congress on Complementary Medicine Research （ICCMR 2008） was held on 29-31 March, 2008 in Sydney, Australia. More than 550 participants from over 30 countries in the diverse field of complementary medicine attended this great event.

Medicinal Model Plants'Breaking the Traditional Medicine Research Methods

Model organisms are the important part of modem life sciences. Arabidopsis thaliana, Oryza sativa, and other model plants have been widely applied in the field of plant science and agronomy, while the international studies on traditional medicine lack the model organisms. Salvia miltiorrhiza, a perennial herb, is one Of the most commonly used medicines.

VEGF in the nervous system: an important target for research in neurodevelopmental and regenerative medicine

Vascular endothelial growth factor（VEGF）in neurodevelopment and regeneration：VEGF is a well-known factor that promotes vascularization and angiogenesis.Besides this it participates in the pathogenesis of several diseases,such as colorectal carcinoma,lung cancer or diabetic retinopathy.Within the last decade,VEGF has been successfully integrated into the treatment of such diseases,for example as a therapy for colorectal cancer with the VEGF-receptor （VEGFR）-inhibitor axitinib.

Analysis of the Main Body the Object and their Relationship Concerning Research of Traditional Chinese Medicine

This paper is the analysis of the main body, the object and their relationship concerning research of traditional Chinese medicine. The result proved that the main body of research of traditional Chinese medicine is researchers who possessed the fundamentals of traditional Chinese medicine. It is the objects of research of traditional Chinese medicine that origin of a class of traditional Chinese medical literature consisting of herbals which focus on descriptions of individual drugs; the relationship of the technological process of preparing Chinese medicine, as by parching, roasting, baking, steaming, soaking, and simmering, etc.;and technology of separating, extracting and purifying for composition; traditional Chinese medicine dynamics of one of the 12 two-hour periods into which the day was formerly divided before the introduction of western chronology; compatibility of medicines in active compositions; patent, effectiveness for a given period of time and constantly changing of traditional Chinese medicine.The relationship between the main body and the objects was that the former depends on the latter ones and the main body has subjective initiative as fully as possible.

Opinion on pharmacology research and new drug development from precision medicine

Since President Obama announced the Precision Medicine Initiative from a national strategy perspective in his State of the Union address,precision medicine has rapidly become a world-wide hotspot and drawn global attention in the medical field.Precision medicine aims at applying genetic information of individual diseases to guide his or her diagnosis and treatment.

Train of Thought and Strategy over Strengthening the Research of Treating Hypertension by Integrative Chinese and Western Medicine

The gradually ex—panding number of peo—pie suffering from hy—pertension and the trendof lowering of their ageindicate that one shouldpay more attention tothe illness and tOstrengthen preventionand treatment of it inorder tO elevate clinicaltherapeutic effect,so as

Quality Marker Concept Inspires the Quality Research of Traditional Chinese Medicines

Traditional Chinese medicines （TCMs） have been used in China for thousands of years for the treatment of various diseases, highly treated as the Chinese cultural heritage. It has played the pivotal role in maintaining the health of Chinese people and even the entire globe.

Primary Research on Chinese Medicine Treatment of Androgen-Independent Prostate Cancer

Prostate cancer(PC) is a common malignant tumor in the male seniors,and its incidence has been ascending in China in recent years. Over 80%of the patients are diagnosed as being in the late stage and lose the opportunity of radical operation because of its early stage metastasis. Endocrinotherapy is regarded

To Establish A Body of Evidence on Safety for Postmarketing Chinese Medicine：A New Research Paradigm

The issue of safety evaluation on postmarketing Chinese medicines has become a hot topic in China’s mainland recently. Researchers and decision-makers can obtain a variety of evidence resources about safety in order to evaluate the safety profile for postmarketing Chinese medicines. A registry study on ten Chinese medicine injections for postmarketing surveillance has come to the end. From such a study observing more than 300,000 patients for more than 4 years, a theoretical research question emerges, that is, how to identify and evaluate safety evidence systematically. We put forward a brand new research paradigm on the theory level, which is to establish a body of evidence on safety evaluation for postmarketing Chinese medicine. Therefore, multiple information sources were explored and extracted from preclinical experiments for toxicity, postmarketing clinical trials for efficacy and safety evaluation, registry study for surveillance, retrospective data analysis from hospital information system and spontaneous response system, and case reports and systematic review from literature. Greater efforts for this idea and cooperation with experts in this field both in China and abroad are urgently needed.

The 3rd Symposium on Animal Models of Primates——The Application of Non-Human Primates to Basic Research and Translational Medicine

In order to understand the fundamental questions of the biology of life and to duplicate the pathogenesis of human diseases, animal models using different experimental animals, such as rodents, Drosophila, Caenorhabditis elegans, and zebrafish, have been established and used widely for many decades. The controllability of environmental conditions, the high reproducibility, the ease of scale and the comparability of results, as well as the ability to use different standards for ethical protocols, all make an animal model the ideal tool for carrying out studies on human diseases and the development of novel pharmaceuticals and new therapies （Xue et al., 2014）. An ideal animal model should reflect the complete spectra of a specific human disease, with similar features on the following key issues： （1） genetic basis; （2） anatomy and physiology; （3） pathological response（s） and underlying mechanism（s）; （4） phenotypic endpoints as clinical studies; （5） responsiveness to known drugs with clinical efficacy; and （6） prediction of clinical efficacy （McGonigle and Ruggeri, 2014）.

Research methods in complementary and alternative medicine： an integrative review

The scientific literature presents a modest amount ot evidence m the use or complementary ana al[erna- tire medicine （CAM）. On the other hand, in practice, relevant results are common. The debates among CAM practitioners about the quality and execution of scientific research are important, Therefore, the aim of this review is to gather, synthesize and describe the differentiated methodological models that encompass the complexity of therapeutic interventions. The process of bringing evidence-based medicine into clinical practice in CAM is essential for the growth and strengthening of complementary medicines worldwide.

Objectifying Research on Special Region Corresponding to Five Internal Organs in Colour Inspections of Chinese Medicine

Objective：To study the differences in a special region（SR） corresponding to five internal organs between the young and the elderly and to verify the effectiveness of a developed system for objectifying research in colour inspections of Chinese medicine（CICM）.Methods：An image acquisition device imitating daylight to meet the requirement of CICM was designed.Image processing software based on CICM theory was developed.A total of 83 normal people were sampled and assigned to two groups.The first group（Group I）included 30 people with an average age of 24 ±2,and the second group（Group Ⅱ） included 53 people with an average age of 74 ±4.After image processing,the chromaticity of 10 SRs corresponding to five internal organs was calculated.R,G,and B represent the chromaticity of color red,green,and blue,L indicates color brightness,whereas a and b denote red and yellow respectively.The difference between the young and the elderly was analyzed.Results：（1） The chromaticity of each SR corresponding to five organs was obtained.The average R,G,B,L,a,and b of the sample were 194.4,147.6,119.3,65.2,15.5,and 22.3,respectively.（2） The R,G,B,and L of the young were greater than those of the elderly,but the a and b of the young were less than those of the elderly.（3） A statistically significant difference in each SR was found between the young and the elderly（P0.05）.The total differences for the Lung（Fei）,Heart（Xin）,Liver（Gan）,Spleen（Pi）,and Kidney（Shen） were 50%（3/6）,66.7%（4/6）,66.7%（4/6）,83.3%（5/6）,and 91.7%（33/36）,respectively.However,the Kidney SR had the greatest statistical discrepancy.Conclusion：The old Chinese saying that human Kidney deficiency worsens with age was verified by the results.The objectifying system used to examine CICM was effective.Thus,this system may be used as a basis for further research.

TAKING THE PATH OF COMBINING TRADITIONAL CHINESE MEDICINE WITH WESTERN MEDICINE IN CANCER RESEARCH AND CONTROL

Chinese oncologists have made great progress on the prevention and treatment of tumor with the combined traditional Chinese medicine (TCM) and Western Medicine (WM). Combining TCM with WM features the cancer research and control in China and has obtained world attention. Researches on cancer prevention with TCM. According to the theories of TCM, cancer is the result of the long-term action of carcinogenic factors under the condition of "Internal Insufficiency" of the body. Some chronic inflammatory changes could cause epithelial cell proliferation and malignant changes. Consequently, TCM treatment for precancerous lesions is very important. The interrup tion effect of Liuwei Dihuang decoction (六味地汤) in severe epithelial atypical hyperplasia of

Exploration and Reflection on Perioperative Researches on Integrative Medicine

At the end of the 20th Century, due to changes in medical thinking, the interest in perioperative research increased. In 1999, Kehlet of Denmark put forward the concept of ＂Accelerated Rehabilitation Technique＂ and made related studies, It was at this time that new concepts such as ＂Damage Control Operations＂ and ＂Fast Track Surgery＂ was introduced in the conventional surgical practice, which prioritizes the survival rate and the quality of life of patients over the success rate of the operation.

Scientific Research at Fujian Academy of Integrative Medicine:Current Status and Future Directions

The Fujian Academy of Integrative Medicine,located in the West Coast of the Taiwan Strait,was founded on July 3,2005 under the Chairmanship of Dr.CHEN Ke-ji,who is an academician of Chinese Academy of Sciences（CAS,Figure 1）.With the mission of using new

Special Issue "Research Progress on Traditional Chinese Medicine and Medicinal Resources" calls for papers

In this special issue of Research Progress on Traditional Chinese Medicine and Medicinal Resources,articles describing the current advances of research on traditional Chinese medicine(TCM)will be invited for submission.The directions of submissions include but not limited to:1.The separation and identification of the chemical components of TCM,pharmacological

State Key Laboratory of Quality Research in Chinese Medicine(Macao University of Science and Technology)

The State Key Laboratory of Quality Research in Chinese Medicine （Macao University of Science and Technology） was formally established on January 25, 2011 upon approval from the Ministry of Science and Technology of China. It is so far the only State Key Laboratory （SKL） specifically in the field of Traditional Chinese Medicine （TCM） over the country. It is also the jothed-laboratory partner of the State Key Laboratory of Natural and Biomimetic Drugs at the Peking University.