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Reflection of Plane Waves from a Free Surface of an Initially Stressed Transversely Isotropic Dissipative Medium 被引量:2
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作者 Baljeet Singh Jyoti Arora 《Applied Mathematics》 2011年第9期1129-1133,共5页
The governing equations of a transversely isotropic dissipative medium are solved analytically to obtain the speeds of plane waves. The appropriate solutions satisfy the required boundary conditions at the stress-free... The governing equations of a transversely isotropic dissipative medium are solved analytically to obtain the speeds of plane waves. The appropriate solutions satisfy the required boundary conditions at the stress-free surface to obtain the expressions of the reflection coefficients of reflected quasi-P (qP) and quasi-SV (qSV) waves in closed form for the incidence of qP and qSV waves. A particular model is chosen for numerical computation of these reflection coefficients for a certain range of the angle of incidence. The numerical values of these reflection coefficients are shown graphically against the angle of incidence for different values of initial stress parameter. The impact of initial stress parameter on the reflection coefficients is observed significantly. 展开更多
关键词 Transversely ISOTROPIC DISSIPATIVE medium Initial stress Plane Waves REFLECTION REFLECTION COEFFICIENTS
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Peristaltic flow of couple stress fluid through uniform porous medium 被引量:2
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作者 A.ALSAEDI N.ALI +1 位作者 D.TRIPATHI T.HAYAT 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2014年第4期469-480,共12页
Investigation concerning peristaltic motion of couple stress fluid is made. An incompressible couple stress fluid occupies the porous medium. Mathematical anal- ysis is presented through large wavelength and low Reyno... Investigation concerning peristaltic motion of couple stress fluid is made. An incompressible couple stress fluid occupies the porous medium. Mathematical anal- ysis is presented through large wavelength and low Reynolds number. Exact analytical expressions of axial velocity, volume flow rate, pressure gradient, and stream function are calculated as a function of couple stress parameter. The essential feature of the analysis is a full description of influence of couple stress parameter and permeability parameter on the pressure, frictional force, mechanical efficiency, and trapping. 展开更多
关键词 PERISTALSIS couple stress fluid porous medium mechanical efficiency trapping
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The Strain/Stress Fields of a Subsurface Rectangular Dislocation Loop Parallel to the Surface of a Half Medium: Analytical Solution with Verification
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作者 Luo Li Tariq A. Khraishi Abu Bakar Siddique 《Journal of Applied Mathematics and Physics》 2021年第1期146-175,共30页
The strain and stress fields of a rectangular dislocation loop in an isotropic solid that is a semi-infinite medium (half medium) are developed here for a Volterra-type dislocation. Specifically, the loop is parallel ... The strain and stress fields of a rectangular dislocation loop in an isotropic solid that is a semi-infinite medium (half medium) are developed here for a Volterra-type dislocation. Specifically, the loop is parallel to the free surface of the solid. The elastic fields of the dislocation loop are developed by integrating the displacement equation of infinitesimals dislocation loops over a finite rectangular loop area below the free surface. The strains and stress then follow from the small strain tensor and Hooke’s law for isotropic materials, respectively. In this paper, analytical verification and numerical verification for the elastic fields are both demonstrated. Equilibrium equations and strain compatibility equations are applied in the verification. Also, a comparison with a newly-developed numerical method for dislocations near a free surface is performed as well. The developed solution is a function of the loop depth beneath the surface and can be used as a fundamental solution to solve elasticity, plasticity or dislocation problems. 展开更多
关键词 Dislocation Loops Free Surfaces VOLTERRA Image-stresses Semi-Infinite medium
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基于波动应力信息的隧道地质三维超前探测技术
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作者 娄国充 宋杨 李岳林 《地下空间与工程学报》 CSCD 北大核心 2024年第5期1656-1664,共9页
在隧道施工过程中,地质超前预报技术是必要手段和工序,也是制约隧道施工技术发展的关键技术难题。地震波法隧道超前地质预报施作是一个力学过程。本文将隧道围岩假设为固、气(孔隙)双相介质,在Biot波动理论的基础上,通过分析人工地震波... 在隧道施工过程中,地质超前预报技术是必要手段和工序,也是制约隧道施工技术发展的关键技术难题。地震波法隧道超前地质预报施作是一个力学过程。本文将隧道围岩假设为固、气(孔隙)双相介质,在Biot波动理论的基础上,通过分析人工地震波引起的围岩应力应变关系,结合反射面处的地震波入射、折射、透射连续方程及波阻抗与反射系数关系,得到了围岩广义应力梯度与地震波瞬时振幅与瞬时频率之间的关系表达式,并建立了围岩应力信息与地质信息的联系。在此基础上,将隧道围岩广义应力梯度作为评价地质灾害的重要指标,形成了基于围岩应力信息的地震波超前地质预报方法,解决了现有预报多解性问题。经过现场试验验证,围岩应力信息能够很好地表达地质岩性变化,结合波速和走时,可以准确判定地质灾害规模、类型及位置。 展开更多
关键词 双相介质 BIOT理论 应力梯度 超前探测 隧道
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基于VTI介质的页岩储层地应力预测方法及应用研究
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作者 何成 程冰洁 《物探化探计算技术》 CAS 2024年第3期262-271,共10页
地应力对页岩气的采集及储层改造具有重要的指导作用,准确的地应力预测可以为优化压裂改造提供依据。页岩储层纵向上存在各向异性特征,为提高页岩储层地应力预测精度,将页岩储层等效为横向各向同性介质(VTI)模型,结合等效模型刚度矩阵... 地应力对页岩气的采集及储层改造具有重要的指导作用,准确的地应力预测可以为优化压裂改造提供依据。页岩储层纵向上存在各向异性特征,为提高页岩储层地应力预测精度,将页岩储层等效为横向各向同性介质(VTI)模型,结合等效模型刚度矩阵参数、弹性系数及结构应变系数,开展页岩储层地应力场及应力差异比的三维模拟,预测水平主应力值、应力方向及应力差异比;并将地应力与储层裂缝、含气量相关参数相结合,分析三者之间存在的联系,并将该方法应用于试验工区龙马溪组页岩储层的地应力预测中。结果表明,基于VTI介质模型的地应力预测结果相较于基于各向同性模型的精度更高,工区应力差异比整体较大,进行压裂改造较困难,压裂不易形成较好的裂缝网络;随水平最大主应力的增大,曲率值减小,含气量存在减小的趋势。 展开更多
关键词 页岩储层 VTI介质 地应力 应力差异比 裂缝 含气量
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不耦合装药下岩石爆破块体尺寸的分布特征
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作者 马泗洲 刘科伟 +1 位作者 杨家彩 李旭东 《爆炸与冲击》 EI CAS CSCD 北大核心 2024年第4期120-138,共19页
通过不同装药结构下立方体红砂岩小型爆破实验,分析了岩石的损伤程度和破坏模式,同时引入三参数极值分布函数量化岩石爆破块体尺寸分布特征。此外,根据岩样R1的爆破实验结果进行了有限元数值模型验证,基于验证的模型展开了岩石单孔爆破... 通过不同装药结构下立方体红砂岩小型爆破实验,分析了岩石的损伤程度和破坏模式,同时引入三参数极值分布函数量化岩石爆破块体尺寸分布特征。此外,根据岩样R1的爆破实验结果进行了有限元数值模型验证,基于验证的模型展开了岩石单孔爆破损伤破裂行为的模拟,讨论了径向、轴向不耦合系数和耦合介质对岩石破碎效果的影响。结果表明,三参数极值分布函数可以较好地表征岩石爆破后破碎块体尺寸分布特征,块体平均尺寸随着不耦合系数的减小呈线性降低趋势,且破碎块度趋于均匀。通过比较不同耦合介质装药时岩石内部的能量分布特征和破坏体积发现,水作为耦合介质时,爆炸能量的传递效率最高,其次分别是湿砂和干砂,空气的能量传递效率最低。结合等效波阻法计算的理论应力透射系数可以很好地反映不耦合装药时岩石的破碎程度。 展开更多
关键词 不耦合装药 耦合介质 岩石块度 爆炸能量 应力透射系数
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间充质干细胞治疗皮瓣缺血再灌注损伤的作用机制及优势
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作者 何波 何志军 +3 位作者 刘涛 马岁录 魏晓涛 王威威 《中国组织工程研究》 CAS 北大核心 2024年第25期4065-4071,共7页
背景:间充质干细胞因具有抗氧化、抑制炎症反应和诱导血管新生等作用而被用于皮瓣缺血再灌注损伤中。目的:综述间充质干细胞在治疗皮瓣缺血再灌注损伤方面的作用机制和最新进展,为其进一步理论研究和临床合理应用提供依据。方法:检索CNK... 背景:间充质干细胞因具有抗氧化、抑制炎症反应和诱导血管新生等作用而被用于皮瓣缺血再灌注损伤中。目的:综述间充质干细胞在治疗皮瓣缺血再灌注损伤方面的作用机制和最新进展,为其进一步理论研究和临床合理应用提供依据。方法:检索CNKI中国期刊全文数据库、万方数据库和PubMed数据库收录的相关文献。中文检索词为“间充质干细胞;皮瓣缺血再灌注损伤;条件培养基;外泌体;氧化应激;炎症反应;血管新生”。英文检索词为“mesenchymal stem cells;flap ischemia reperfusion injury;Conditioned medium;exosomes;Oxidative stress;Inflammatory reaction;Angiogenesis”。检索2010年以来相关文献,通过阅读文章剔除研究内容与文章主题关系不大、质量较差及内容陈旧文献,最终纳入74篇文献进行归纳总结。结果与结论:①间充质干细胞在抗氧化、抑制炎性反应及诱导血管新生等方面作用显著,在治疗皮瓣缺血再灌注损伤中蕴含着巨大潜力。②然而,间充质干细胞自身的缺陷及近年来治疗效果的下降使间充质干细胞的发展和应用陷入了瓶颈期,间充质干细胞条件培养基及其外泌体和间充质干细胞可塑性研究应运而生,且治疗效果明显优于单纯使用间充质干细胞。③因此,更全面地了解间充质干细胞治疗皮瓣缺血再灌注损伤的作用机制和最新治疗进展,对于间充质干细胞的研究和皮瓣缺血再灌注损伤的治疗都具有非常重要的意义。 展开更多
关键词 间充质干细胞 皮瓣缺血再灌注损伤 条件培养基 外泌体 氧化应激 炎症反应 血管新生
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三维黏弹性模型在月球冷却产生的热应力计算中的应用
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作者 金一民 陶莎 石耀霖 《中国科学院大学学报(中英文)》 CSCD 北大核心 2024年第1期1-10,共10页
月球冷却过程中积累的热应力是影响月球内部力学环境的重要因素之一。使用三维黏弹性有限元模型计算月球热应力的积累过程,并通过对比实验分析黏性参数对热应力大小的影响。计算结果表明月幔深部和浅部的热应力状态存在截然的分界。浅... 月球冷却过程中积累的热应力是影响月球内部力学环境的重要因素之一。使用三维黏弹性有限元模型计算月球热应力的积累过程,并通过对比实验分析黏性参数对热应力大小的影响。计算结果表明月幔深部和浅部的热应力状态存在截然的分界。浅部热应力以切向挤压为主,挤压应力最大值出现在月壳底部;深部径向和切向正应力的大小主要受浅部径向正应力的控制,径向和切向热应力均为拉张,但由于黏性松弛差应力的积累和松弛动态平衡,而处于接近“静水压”状态。假设月球岩石圈的黏度大于10^(28)Pa·s,则现今月壳和浅部月幔水平挤压热应力可以达到数百MPa,而月幔深部的拉张热应力可达到数十~100 MPa。因此,震源深度较浅的浅源月震可以用热应力来解释。而深源月震成因仍是一个困难的问题,推测深部月幔的拉张热应力为孔隙结构的发育提供了条件,而月幔底部的熔融层提供了高压孔隙流体,从而降低了深部月幔介质的破裂强度。 展开更多
关键词 黏弹性介质 有限元法 热应力 月震
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中主应力对输电线路地基土强度影响研究
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作者 郑晓云 徐旭东 +4 位作者 钱成雷 王峥 郑海鹰 朱心宇 黄学海 《城市建筑》 2024年第4期227-229,共3页
在静动荷载联合作用下,输电线路地基土所受到的应力路径十分复杂,同时在不同的输电线路路基上外界荷载或地形等因素也会对土体强度产生影响。为研究应力路径对土体的强度影响,文章采用空心圆柱扭剪仪(HCA)进行了一系列控制中主应力系数... 在静动荷载联合作用下,输电线路地基土所受到的应力路径十分复杂,同时在不同的输电线路路基上外界荷载或地形等因素也会对土体强度产生影响。为研究应力路径对土体的强度影响,文章采用空心圆柱扭剪仪(HCA)进行了一系列控制中主应力系数的定向剪切单元体试验。通过施加轴力和扭转模拟现实中的复杂路径,控制围压和中主应力系数b模拟现实中的复杂荷载情况,借此研究了不同中主应力系数和剪切角度对砂土的沉降和剪切强度的影响。研究表明:砂土的轴向破坏应力随角度的增大而减小;破坏广义剪应力随角度的增大而减小,并表现出明显的硬化;砂土的破坏广义剪应力与b值呈现负相关。 展开更多
关键词 中密砂 定向剪切 中主应力系数 破坏强度
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可调直角管接头高压密封设计
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作者 丛玉利 郭亚萍 《汽车零部件》 2024年第6期12-14,17,共4页
中重型商用车液压助力转向系统的介质压力很高,甚至能达到18 MPa,这对管接头的密封性提出了很高要求。在北汽福田公司,目前用于18 MPa介质压力下的管接头密封类型有3种,包括卡套式、铜平垫式、铜平垫硫化橡胶组合垫圈式,没有单纯橡胶密... 中重型商用车液压助力转向系统的介质压力很高,甚至能达到18 MPa,这对管接头的密封性提出了很高要求。在北汽福田公司,目前用于18 MPa介质压力下的管接头密封类型有3种,包括卡套式、铜平垫式、铜平垫硫化橡胶组合垫圈式,没有单纯橡胶密封的类型。鉴于此,整合文献成果,提出一种橡胶密封的设计方法,并将其与成熟的铜平垫式管接头密封方式相组合,形成了可调直角管接头高压密封产品设计方案。经过样品试验和批量验证,可知该设计方案的密封效果良好。 展开更多
关键词 密封槽 压缩率 橡胶密封 橡胶硬度 接触应力 介质压力
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中温回火温度对22MnB5钢扭力梁疲劳性能的影响
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作者 张燕呢 闵永安(导师) 陈荣 《机械工程材料》 CAS CSCD 北大核心 2024年第2期56-61,共6页
对冷成形22MnB5钢管状扭力梁进行960℃感应淬火和中温回火,研究了回火温度(220,350,400,450,500℃)对扭力梁拉伸性能、冲击性能和疲劳寿命的影响。结果表明:随着回火温度从350℃升至500℃,22MnB5钢扭力梁的抗拉强度降低,断后伸长率增加... 对冷成形22MnB5钢管状扭力梁进行960℃感应淬火和中温回火,研究了回火温度(220,350,400,450,500℃)对扭力梁拉伸性能、冲击性能和疲劳寿命的影响。结果表明:随着回火温度从350℃升至500℃,22MnB5钢扭力梁的抗拉强度降低,断后伸长率增加,强塑积先增大后减小,450℃回火后最大,达到12.3 GPa·%;随着回火温度从220℃升至450℃,22MnB5钢扭力梁显微硬度减小,冲击吸收力增加;回火后扭力梁表面残余应力下降,且回火温度越高,下降程度越大;随回火温度升高,扭力梁疲劳寿命呈先下降后增再降的变化趋势,450℃回火疲劳寿命最长,达(15.8±2.4)万次;22MnB5钢扭力梁的最佳回火温度为450℃。 展开更多
关键词 高强钢 中温回火 扭力梁 残余应力 疲劳
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鲁氏接合酵母对高盐和高温胁迫响应的差异性与共性分析
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作者 刘梦奇 闫珍珍 +2 位作者 胡娜 陈雄 李欣 《食品科学》 EI CAS CSCD 北大核心 2024年第2期79-88,共10页
针对高温(40℃)和高盐(18%NaCl)逆境设计了最低营养需求全合成培养基,分析了鲁氏接合酵母(Zygosaccharomyces rouxii)在长期逆境下生长的营养需求差异,重点解析了酵母细胞从生长适应期到对数生长初期阶段有机酸、氨基酸和糖类物质的代... 针对高温(40℃)和高盐(18%NaCl)逆境设计了最低营养需求全合成培养基,分析了鲁氏接合酵母(Zygosaccharomyces rouxii)在长期逆境下生长的营养需求差异,重点解析了酵母细胞从生长适应期到对数生长初期阶段有机酸、氨基酸和糖类物质的代谢及基因表达差异。研究结果显示,遭遇高盐压力的鲁氏接合酵母细胞更需要外源氨基酸,而补充维生素和氨基酸有助于缓解酵母细胞的高温压力。鲁氏接合酵母针对高盐和高温逆境采用了差异明显的有机酸、氨基酸和糖代谢策略。MSN4(逆境转录子基因)和HOG1(高渗调控蛋白基因)响应高盐,而HSF1(热激调控蛋白基因)和SOD1(超氧化物歧化酶基因)对高温响应。本研究加深了对耐盐鲁氏接合酵母耐温机制的理解,有助于双抗新能力酿造酵母菌株的研制。 展开更多
关键词 鲁氏接合酵母 高盐逆境 高温逆境 全合成培养基 营养需求 代谢差异 基因表达
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Effect of high-temperature pre-precipitation on mechanical properties and stress corrosion cracking of Al-Zn-Mg alloys 被引量:14
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作者 李松 陈康华 +2 位作者 刘红卫 黄兰萍 张茁 《中国有色金属学会会刊:英文版》 CSCD 2003年第3期585-589,共5页
In order to improve the stress corrosion cracking resistance of the weldable Al Zn Mg alloys with medium strength, the near solvus pre precipitation following high temperature solution treatment was performed on LC52 ... In order to improve the stress corrosion cracking resistance of the weldable Al Zn Mg alloys with medium strength, the near solvus pre precipitation following high temperature solution treatment was performed on LC52 and 7039 aluminum alloys. The effect of the pre precipitation on the microstructure, age hardening and stress corrosion cracking of LC52 and 7039 alloy was investigated. The results show that the near solvus pre precipitation can be limited on grain boundary and can enhance the discontinuity of grain boundary precipitates. The stress corrosion cracking resistance of aged Al Zn Mg alloys can be improved with non deteriorated strength and plasticity via pre precipitation. 展开更多
关键词 AL-ZN-MG合金 铝合金 应力腐蚀断裂 高温预沉淀 机械性能
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Reflection of Plane Waves from Free Surface of an Initially Stressed Rotating Orthotropic Dissipative Solid Half-Space 被引量:1
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作者 Baljeet Singh Jyoti Arora 《Engineering(科研)》 2012年第3期170-175,共6页
The governing equations of an initially stressed rotating orthotropic dissipative medium are solved analytically to obtain the velocity equation which indicates the existence of two quasi-planar waves. The appropriate... The governing equations of an initially stressed rotating orthotropic dissipative medium are solved analytically to obtain the velocity equation which indicates the existence of two quasi-planar waves. The appropriate particular solutions in the half-space satisfy the required boundary conditions at the stress-free surface to obtain the expressions of the reflec-tion coefficients of the reflected quasi-P (qP) and reflected quasi-SV (qSV) waves in closed form for the incidence of qP and qSV waves. A particular model is chosen for numerical computation of these reflection coefficients for a certain range of the angle of incidence. The numerical values of these reflection coefficients are shown graphically against the angle of incidence for different values of initial stress parameter and rotation parameter. The impact of initial stress and rotation parameters on the reflection coefficients is observed significantly. 展开更多
关键词 ORTHOTROPIC DISSIPATIVE medium Initial stress Rotation Plane WAVES REFLECTION REFLECTION COEFFICIENTS
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Influence caused by initial tectonic stress on relative measurement of borehole groundstresinviscoelasticmedia
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作者 赵鹏君 沈建文 《Acta Seismologica Sinica(English Edition)》 CSCD 1996年第3期30-39,共10页
In this paper, we discussed the influence of the initial tectonic stress on the relative measurement value of the ground stress when a long cylindrical straingauge is used in the viscoelastic media. We simulate the... In this paper, we discussed the influence of the initial tectonic stress on the relative measurement value of the ground stress when a long cylindrical straingauge is used in the viscoelastic media. We simulate the whole system consisting of the stratum, cement ring and the straingauge cylinder with a three layer medium model and obtain the solution of radial displacement on the inner wall of the straingauge under the action of initial tectonic stress by using the correspondence principle. The result showes: 1) The influence of initial stress making of the radial displacement on the inner wall of the straingauge increases gradually with time at a gradually reduced rate and tends to a certain value eventually; 2) The principal stress with a magnitude of [C 0+C 1 exp (- ω 1t)+ C 2 exp(- ω 2t )] σ i0 in the opposite direction of initial stress will be superimposed to the measuring result of stress change without considering the initial stress. where C 0, C 1, C 2 and ω 1, ω 2 are related only to the mechanical property of the stratum, σ i0 (i=1, 2) are the two principal components of the initial tectonic stress. It is pointed out that the initial tectonic stress affects obviously on the measurement of the relative change of ground stress in the cases of soft strata and high initial stress. 展开更多
关键词 measurement of ground stress vicoelastic medium initial stress.
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Boundary element analysis for elastic and elastoplastic problems of 2D orthotropic media with stress concentration
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作者 Xiushan Sun Lixin Huang +1 位作者 Yinghua Liu Zhangzhi Cen 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2005年第5期472-484,共13页
Both the orthotropy and the stress concentration are common issues in modem structural engineering. This paper introduces the boundary element method (BEM) into the elastic and elastoplastic analyses for 2D orthotro... Both the orthotropy and the stress concentration are common issues in modem structural engineering. This paper introduces the boundary element method (BEM) into the elastic and elastoplastic analyses for 2D orthotropic media with stress concentration. The discretized boundary element formulations are established, and the stress formulae as well as the fundamental solutions are derived in matrix notations. The numerical procedures are proposed to analyze both elastic and elastoplastic problems of 2D orthotropic me- dia with stress concentration. To obtain more precise stress values with fewer elements, the quadratic isoparametric element formulation is adopted in the boundary discretization and numerical procedures. Numerical examples show that there are significant stress concentrations and different elastoplastic behaviors in some orthotropic media, and some of the computational results are compared with other solutions. Good agreements are also observed, which demonstrates the efficiency and reliability of the present BEM in the stress concentration analysis for orthotropic media. 展开更多
关键词 Boundary element method (BEM) . Fundamental solution . Orthotropic medium . stress concentration .Elastic and elastoplastic problems
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CHARACTERISTIC ANALYSIS FOR STRESS WAVE PROPAGATION IN TRANSVERSELY ISOTROPIC FLUID-SATURATED POROUS MEDIA
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作者 刘颖 刘凯欣 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2004年第6期656-663,共8页
According to generalized characteristic theory, a characteristic analysis for stress wave propagation in transversely isotropic fluid-saturated porous media was performed. The characteristic differential equations an... According to generalized characteristic theory, a characteristic analysis for stress wave propagation in transversely isotropic fluid-saturated porous media was performed. The characteristic differential equations and compatibility relations along bicharacteristics were deduced and the analytical expressions for wave surfaces were obtained. The characteristic and shapes of the velocity surfaces and wave surfaces in the transversely isotropic fluid-saturated porous media were discussed in detail. The results also show that the characteristic equations for stress waves in pure solids are particular cases of the characteristic equations for fluid-saturated porous media. 展开更多
关键词 characteristic analysis wave surface fluid-saturated porous medium transversely isotropic stress wave
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Evaluation of the Secretome Profile and Functional Characteristics of Human Bone Marrow Mesenchymal Stromal Cells-Derived Conditioned Medium Suggest Potential for Skin Rejuvenation
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作者 Sudha Balasubramanian Charan Thej +4 位作者 Ankita Walvekar Priyanka Swamynathan Pawan K. Gupta Raviraja N. Seetharam Anish S. Majumdar 《Journal of Cosmetics, Dermatological Sciences and Applications》 2017年第1期99-117,共19页
Background/Purpose: Multipotent bone marrow-derived mesenchymal stromal cells (BMMSC) have been shown to possess the potential for tissue regeneration. The application of mesenchymal stromal cells (MSC)-derived growth... Background/Purpose: Multipotent bone marrow-derived mesenchymal stromal cells (BMMSC) have been shown to possess the potential for tissue regeneration. The application of mesenchymal stromal cells (MSC)-derived growth factors and cytokines (GF/CKs) has been implicated for the repair and regeneration of the damaged skin that occurs due to aging and exposure to environmental stress factors. Methods: We have used both qualitative and quantitative measurements of the GF/CKs from the conditioned medium (CM) of a pooled population of BMMSC by antibody array analysis as well as by enzyme-linked immunosorbent assay (ELISA). Furthermore, the CM was also used in a variety of in vitro biological assays to measure its protective properties in human skin fibroblasts. Results: We have characterized the secretome of BMMSC by analyzing the composition of the CM using a forty-one growth factor array system. Thirteen of these GF/CK/extra cellular matrix (ECM)/ matrix metalloproteinases (MMP)-inhibitors in the CM were quantified owing to their involvement in skin repair cascade. In addition, we report that the BMMSC-CM was also able to protect dermal fibroblasts against tert-Butyl hydro peroxide (tbOH) induced oxidative stress and ultra violet B (UV-B) radiation induced cell damage. Conclusion: Based on the data presented here, we propose that BMMSC-derived CM may have the potential to promote health and rejuvenation of the aging skin. 展开更多
关键词 Bone Marrow-Derived MSC Conditioned medium SECRETOME OXIDATIVE stress UV-B Damage
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“Small earthquake modulation window” and its applications in medium-term prediction
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作者 苏鸾声 《Acta Seismologica Sinica(English Edition)》 CSCD 1995年第1期51-56,共6页
Based on the observations of many years, it has been found that “small earthquake modulation windows” exist inthe situation of some special geological structures, which respond sensitively to the variations of regio... Based on the observations of many years, it has been found that “small earthquake modulation windows” exist inthe situation of some special geological structures, which respond sensitively to the variations of regional stressfields and the activities of earthquake swarms greater than moderate strong magnitude, and can supply some precursory information. More than two “small earthquake modulation windows” can also provide a general orientation of the first main earthquake of a earthquake cluster. Compared with “seismic window” based on frequency itis no doubt that the “modulation-window” has an unique characteristic of applicational significance to mediumterm earthquake prediction with a time scale of two or three years. 展开更多
关键词 medium-term prediction small earthquake activity stress rield EARTHQUAKE seismogenic window
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Research on seismic stress triggering
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作者 万永革 吴忠良 +2 位作者 周公威 黄静 秦立新 《Acta Seismologica Sinica(English Edition)》 CSCD 2002年第5期559-577,共19页
This paper briefly reviews basic theory of seismic stress triggering. Recent development on seismic stress triggering has been reviewed in the views of seismic static and dynamic stress triggering, application of visc... This paper briefly reviews basic theory of seismic stress triggering. Recent development on seismic stress triggering has been reviewed in the views of seismic static and dynamic stress triggering, application of viscoelastic model in seismic stress triggering, the relation between earthquake triggering and volcanic eruption or explosion, other explanation of earthquake triggering, etc. And some suggestions for further study on seismic stress triggering in near future are given. 展开更多
关键词 Coulomb failure stress change seismic static stress triggering seismic dynamic stress triggering viscoelastic medium
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