Meiotic recombination occurs preferentially at certain regions in the genome referred to as hot spots which are important for generating genetic diversity and proper segregation of chromosomes during meiosis.Although ...Meiotic recombination occurs preferentially at certain regions in the genome referred to as hot spots which are important for generating genetic diversity and proper segregation of chromosomes during meiosis.Although observations concerning individual hotspots have given clues as to the mechanism of recombination initiation,the nature and causes of recombination rate variation in the genome are still little known.A rational solution is to estimate and rank recombination rates along the genome.Therefore,it is a high demand for a database that deposits and integrates those data to provide a systematical repository of genome-wide recombination rates.Homologous recombination hotspots database is a web-based database of meiotic recombination rates,which comprises enormous data and information of human,mouse,rat,D.melanogaster,C.elegans and yeast.Users can query the database in several alternative ways.The database stores various details for every sequence,such as chromosome number,hyperlinks to the respective reference,and the sequence in FASTA format.展开更多
文摘Meiotic recombination occurs preferentially at certain regions in the genome referred to as hot spots which are important for generating genetic diversity and proper segregation of chromosomes during meiosis.Although observations concerning individual hotspots have given clues as to the mechanism of recombination initiation,the nature and causes of recombination rate variation in the genome are still little known.A rational solution is to estimate and rank recombination rates along the genome.Therefore,it is a high demand for a database that deposits and integrates those data to provide a systematical repository of genome-wide recombination rates.Homologous recombination hotspots database is a web-based database of meiotic recombination rates,which comprises enormous data and information of human,mouse,rat,D.melanogaster,C.elegans and yeast.Users can query the database in several alternative ways.The database stores various details for every sequence,such as chromosome number,hyperlinks to the respective reference,and the sequence in FASTA format.
