AIM：To investigate clinical features of optic nerve sheath meningioma（ONSM） that was misdiagnosed,and to find methods to reduce the misdiagnoses.METHODS：Retrospective series study.Twenty-five misdisgnosed patients...AIM：To investigate clinical features of optic nerve sheath meningioma（ONSM） that was misdiagnosed,and to find methods to reduce the misdiagnoses.METHODS：Retrospective series study.Twenty-five misdisgnosed patients with unilateral ONSM were collected from Jan.2008 to Jan.2015 and the clinical records reviewed.RESULTS：Patients were misdiagnosed with acute papillitis most frequently（P=17）,immediately followed by optic atrophy（P=8）,ischemic optic neuropathy（P=5）,acute retrobulbar optic neuritis（P=5）,optic disc vasculitis（P =3）.For each patient,the minimum frequency of misdiagnoses was once and the maximum was 4 times.As for the lasting time of being misdiagnosed,the shortest was 1.5mo and the longest was 45 mo.Twentyone cases（84%） were once treated with glucocorticoids,and its side effects was found in seventeen patients.Twenty patients（80%） complained with varying degree of vision loss.When a definite diagnosis was made,sixteen cases（64%） showed slight exophthalmos and eighteen cases（72%） had the tubular ONSM.CONCLUSION：ONSM without loss obvious exophthalmos is easily misdiagnosed in clinic,and for most of these ONSMs are tubular.展开更多
目的研究眼眶肿瘤致视野改变的类型及相关因素。方法利用Humphrey720i计算机自动视野计对眼眶肿瘤患者进行视野检查,对研究结果进行分析。结果眶中部或眶尖肿瘤对普遍敏感性降低的影响存在显著性;视神经内侧受压对各象限阈值的影响无显...目的研究眼眶肿瘤致视野改变的类型及相关因素。方法利用Humphrey720i计算机自动视野计对眼眶肿瘤患者进行视野检查,对研究结果进行分析。结果眶中部或眶尖肿瘤对普遍敏感性降低的影响存在显著性;视神经内侧受压对各象限阈值的影响无显著性,其余各方(上、下、外)对其影响均有显著性,视神经受压部位与各象限阈值降低之间的关系差异无显著性;肿瘤是否压迫眼球后壁和肿瘤在眶内位置均是造成平均缺损(mean defect,MD)和模式标准差(pattern standard deviation,PSD)下降的因素,肿瘤在眶内位置较肿瘤是否压迫眼球后壁更易引起视野指数下降,眶中部肿瘤和眶尖肿瘤之间MD无明显差别(P<0.05),但眶尖肿瘤对PSD的影响较眶中部肿瘤更为明显(P<0.05);随访分析表明压迫因素引起的视野改变为可逆的。结论眶尖肿瘤可造成视网膜光敏感性降低;眶尖肿瘤更易引起视野缺损;肿瘤压迫视神经可造成各象限视敏度降低;视神经受压部位与视野缺损方位无明显对应关系。展开更多
文摘AIM：To investigate clinical features of optic nerve sheath meningioma（ONSM） that was misdiagnosed,and to find methods to reduce the misdiagnoses.METHODS：Retrospective series study.Twenty-five misdisgnosed patients with unilateral ONSM were collected from Jan.2008 to Jan.2015 and the clinical records reviewed.RESULTS：Patients were misdiagnosed with acute papillitis most frequently（P=17）,immediately followed by optic atrophy（P=8）,ischemic optic neuropathy（P=5）,acute retrobulbar optic neuritis（P=5）,optic disc vasculitis（P =3）.For each patient,the minimum frequency of misdiagnoses was once and the maximum was 4 times.As for the lasting time of being misdiagnosed,the shortest was 1.5mo and the longest was 45 mo.Twentyone cases（84%） were once treated with glucocorticoids,and its side effects was found in seventeen patients.Twenty patients（80%） complained with varying degree of vision loss.When a definite diagnosis was made,sixteen cases（64%） showed slight exophthalmos and eighteen cases（72%） had the tubular ONSM.CONCLUSION：ONSM without loss obvious exophthalmos is easily misdiagnosed in clinic,and for most of these ONSMs are tubular.
文摘目的研究眼眶肿瘤致视野改变的类型及相关因素。方法利用Humphrey720i计算机自动视野计对眼眶肿瘤患者进行视野检查,对研究结果进行分析。结果眶中部或眶尖肿瘤对普遍敏感性降低的影响存在显著性;视神经内侧受压对各象限阈值的影响无显著性,其余各方(上、下、外)对其影响均有显著性,视神经受压部位与各象限阈值降低之间的关系差异无显著性;肿瘤是否压迫眼球后壁和肿瘤在眶内位置均是造成平均缺损(mean defect,MD)和模式标准差(pattern standard deviation,PSD)下降的因素,肿瘤在眶内位置较肿瘤是否压迫眼球后壁更易引起视野指数下降,眶中部肿瘤和眶尖肿瘤之间MD无明显差别(P<0.05),但眶尖肿瘤对PSD的影响较眶中部肿瘤更为明显(P<0.05);随访分析表明压迫因素引起的视野改变为可逆的。结论眶尖肿瘤可造成视网膜光敏感性降低;眶尖肿瘤更易引起视野缺损;肿瘤压迫视神经可造成各象限视敏度降低;视神经受压部位与视野缺损方位无明显对应关系。
