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Analysis of therapeutic efficacy of Aredia in treating pain caused by advanced malignant metastatic bone tumors
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作者 劳逸 王伟 +2 位作者 陈绍锋 胡建新 吕德政 《中国组织工程研究与临床康复》 CAS CSCD 2001年第24期148-,共1页
Objective To study therapeutic efficacy of Aredia in treating malignant metastatic bone tumors. Method 60~90 mg Aredia was administrated iv in 31 cases with malignant metastatic tumors,once each week. Results Pain in... Objective To study therapeutic efficacy of Aredia in treating malignant metastatic bone tumors. Method 60~90 mg Aredia was administrated iv in 31 cases with malignant metastatic tumors,once each week. Results Pain in 12 cases was significantly relieved.14 cases acquired relif.Total effective rate was 83.9%.Activity ability was improved by 80.6%.No apparent toxicological and adverse effects as well as fever and cold symptoms were observed.Conclusion Aredia is a kind of ideal drugs for treatment of pain caused by malignant metastatic bone tumors.It is convenient in use and could be endured by patients. 展开更多
关键词 aredia malignant tumors metastatic bone tumors PAIN
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Clinical research on zoledronic acid in treatment of pain caused by bone metastasis of malignant tumors
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作者 Zhuang Yu Jun Liang Ling Peng 《The Chinese-German Journal of Clinical Oncology》 CAS 2007年第4期399-401,共3页
Objective:To evaluate the efficacy and safety of zoledronic acid for the pain caused by metastatic tumor of bone.Methods:52 patients with metastatic tumor of bone were randomly divided into two groups.The zoledronic a... Objective:To evaluate the efficacy and safety of zoledronic acid for the pain caused by metastatic tumor of bone.Methods:52 patients with metastatic tumor of bone were randomly divided into two groups.The zoledronic acid group received 4 mg zoledronic acid infusion for 30 minutes and the control group received 90 mg pamidronate infusion for 6 hours. Results:The effective rates in zoledronic acid group and control group were 73.08%and 69.23%respectively.No significant difference was observed between the two groups.The median pain relief onset at days 5 and 7,respectively,and no significant difference was observed.The ECOG scores on the 7th day after medication:the differences in the zoledronic acid group before and after medication and between the two groups were both significant(P<0.001 and P=0.0448).The adverse reac- tion was no significant difference between the two groups.Conclusion:Zoledronic acid is efficient and safe in the treatment of pain caused by metastatic tumor of bone and it has low adverse reaction rate and convenient shorter using time. 展开更多
关键词 zoledronic acid PAMIDRONATE metastatic tumor of bone bone pain
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