气象观测场在汽车试验场中的应用研究

汽车试验场作为汽车开展道路测试的重要场所,用于验证汽车产品的品质以及可靠性。除了场地道路外,气象条件作为汽车道路测试的重要一环,在《GB/T12534-1990汽车道路试验方法通则》中也有明确要求,如:试验时应是无雨无雾天气,相对湿度小于95%,气温0-40℃,风速不大于3m/s。同时气象条件也作为试验场道路管控的重要依据,实时风速、雨量、能见度等信息为场地管理者发布限速、限行、封场等通知提供必要参考依据,直接影响道路测试安全管控的及时性。因此,文章从气象观测场的建设、气象服务、异常天气道路管控等方面开展气象观测场在汽车试验场中的应用研究。

IUID Method-Mix: Towards a Systematic Approach for Intercultural User Interface Design (IUID)

A method-mix for intercultural user interface design (IUID) is explained and exemplified by application examples based on a hybrid approach covering cultural contexts in human-computer interaction (HCI) design using a model of culturally influenced HCI. Cultural influence on HCI is described using cultural variables for user interface design. Assumptions and empirical results regarding the influence of culture on HCI, considering the path of the information processing and the interaction style between Chinese and German users are explained based on cultural models. Subsequent indicators represent the relationship between culture and HCI (culturally imprinted by the user). Correlations adopted theoretically between cultural dimensions and variables for HCI design were investigated. These correlations represent relevant constituents of a model for culturally influenced HCI. Considerations applying this model and evidence for the proper application of the IUID method-mix are presented elucidating why and how cultural aspects play a role in HCI design and usability/UX engineering. The IUID method-mix serves to inspire HCI engineers in the requirement analysis phase as well as HCI designers in the design phase. The readers are thereby sensitized to the challenges of intercultural usability/UX engineering and intercultural HCI design and will be equipped with methodological knowledge relevant to the derivation of design recommendations for user interface design for and in their desired cultural contexts. Finally, implications for practitioners are shown, including HCI style scores and practical design recommendations, to prognosticate the effort and the expenditures for considering the cultural context in IUID.

A Kinetic Study of Anaerobic Biodegradation of Food and Fruit Residues during Biogas Generation Using Initial Rate Method

A kinetic study of biogas production from Urban Solid Waste (USW) generated in Dar es Salaam city (Tanzania) is presented. An experimental bioreactor simulating mesophilic conditions of most USW landfills was developed. The goal of the study was to generate the kinetic order of reaction with respect to biodegradable organic waste and use it to model biogas production from food residues mixed with fruit waste. Anaerobic biodegradation was employed under temperature range of 28℃ - 38℃. The main controls were leachate recirculation and pH adjustments to minimize acid inhibitory effects and accelerate waste biodegradation. The experimental setup comprised of three sets of bioreactors. A biodegradation rate law in differential form was proposed and the numerical values of kinetic order and rate constant were determined using initial rate method as 0.994 and 0.3093 mol0.006·day-1, respectively. Results obtained were consistent with that found in literature and model predictions were in reasonable agreement with experimental data.

Numerical Solution of Nonlinear System of Partial Differential Equations by the Laplace Decomposition Method and the Pade Approximation

In this paper, Laplace decomposition method (LDM) and Pade approximant are employed to find approximate solutions for the Whitham-Broer-Kaup shallow water model, the coupled nonlinear reaction diffusion equations and the system of Hirota-Satsuma coupled KdV. In addition, the results obtained from Laplace decomposition method (LDM) and Pade approximant are compared with corresponding exact analytical solutions.

A Study of EM Algorithm as an Imputation Method: A Model-Based Simulation Study with Application to a Synthetic Compositional Data

Compositional data, such as relative information, is a crucial aspect of machine learning and other related fields. It is typically recorded as closed data or sums to a constant, like 100%. The statistical linear model is the most used technique for identifying hidden relationships between underlying random variables of interest. However, data quality is a significant challenge in machine learning, especially when missing data is present. The linear regression model is a commonly used statistical modeling technique used in various applications to find relationships between variables of interest. When estimating linear regression parameters which are useful for things like future prediction and partial effects analysis of independent variables, maximum likelihood estimation (MLE) is the method of choice. However, many datasets contain missing observations, which can lead to costly and time-consuming data recovery. To address this issue, the expectation-maximization (EM) algorithm has been suggested as a solution for situations including missing data. The EM algorithm repeatedly finds the best estimates of parameters in statistical models that depend on variables or data that have not been observed. This is called maximum likelihood or maximum a posteriori (MAP). Using the present estimate as input, the expectation (E) step constructs a log-likelihood function. Finding the parameters that maximize the anticipated log-likelihood, as determined in the E step, is the job of the maximization (M) phase. This study looked at how well the EM algorithm worked on a made-up compositional dataset with missing observations. It used both the robust least square version and ordinary least square regression techniques. The efficacy of the EM algorithm was compared with two alternative imputation techniques, k-Nearest Neighbor (k-NN) and mean imputation (), in terms of Aitchison distances and covariance.

Exact Traveling Wave Solutions of Nano-Ionic Solitons and Nano-Ionic Current of MTs Using the exp(-φ (ξ ))-Expansion Method

In this work, the exp(-φ (ξ )) -expansion method is used for the first time to investigate the exact traveling wave solutions involving parameters of nonlinear evolution equations. When these parameters are taken to be special values, the solitary wave solutions are derived from the exact traveling wave solutions. The validity and reliability of the method are tested by its applications to Nano-ionic solitons wave’s propagation along microtubules in living cells and Nano-ionic currents of MTs which play an important role in biology.

Risk assessment of coastal flooding disaster by storm surge based on Elevation-Area method and hydrodynamic models:Taking Bohai Bay as an example

The future inundation by storm surge on coastal areas are currently ill-defined.With increasing global sealevel due to climate change,the coastal flooding by storm surge is more and more frequently,especially in coastal lowland with land subsidence.Therefore,the risk assessment of such inundation for these areas is of great significance for the sustainable socio-economic development.In this paper,the authors use Elevation-Area method and Regional Ocean Model System(ROMS)model to assess the risk of the inundation of Bohai Bay by storm surge.The simulation results of Elevation-Area method show that either a 50-year or 100-year storm surge can inundate coastal areas exceeding 8000 km^(2);the numerical simulation results based on hydrodynamics,considering ground friction and duration of the storm surge high water,show that a 50-year or 100-year storm surge can only inundate an area of over 2000 km^(2),which is far less than 8000 km^(2);while,when taking into account the land subsidence and sea level rise,the very inundation range will rapidly increase by 2050 and 2100.The storm surge will greatly impact the coastal area within about 10-30 km of the Bohai Bay,in where almost all major coastal projects are located.The prompt response to flood disaster due to storm surge is urgently needed,for which five suggestions have been proposed based on the geological background of Bohai Bay.This study may offer insight into the development of the response and adaptive plans for flooding disasters caused by storm surge.

Optimization of Open-cast Mining Procedure Based on RSR Method

To explore the optimal evaluation mechanism of open-cast mining procedure,this paper takes the actual operation status of Huolinhe No.1 Open-cast Mine as the research basis,and makes a deep analysis of the four representative mining procedures proposed by this mine.A detailed and comprehensive evaluation system is constructed using rank-sum ratio(RSR)method.The system covers 17 key indicators and aims to evaluate the advantages and disadvantages of each scheme in an all-round and multi-angle manner.Through the calculation and analysis by RSR method,the comprehensive evaluation of the four types of mining procedure schemes is carried out,and finally the secondary river improvement project is determined as the optimal mining implementation scheme,and the joint mining scheme of the south and north areas is the alternative strategy.The research results of this paper are objective,clear and definite,can not only reveal the effectiveness and feasibility of RSR method in solving the problem of open-cast mining procedure optimization,but also provide a strong technical support and decision-making basis for the future production development of Huolinhe No.1 Open-cast Mine.Thus,this study is expected to further promote the scientific and refined process of mining operations.

Application of geophysical methods in fine detection of urban concealed karst:A case study of Wuhan City,China

The construction of modern livable cities faces challenges in karst areas,including ground collapse and engineering problems.Wuhan,with a population of 13.74×10^(6) and approximately 1161 km^(2)of soluble rocks in the urban area of 8569.15 km^(2),predominantly consists of concealed karst areas where occasional ground collapse events occur,posing significant threats to underground engineering projects.To address these challenges,a comprehensive geological survey was conducted in Wuhan,focusing on major karstrelated issues.Geophysical methods offer advantages over drilling in detecting concealed karst areas due to their efficiency,non-destructiveness,and flexibility.This paper reviewed the karst geological characteristics in Wuhan and the geophysical exploration methods for karst,selected eight effective geophysical methods for field experimentation,evaluated their suitability,and proposed method combinations for different karst scenarios.The results show that different geophysical methods have varying applicability for karst detection in Wuhan,and combining multiple methods enhances detection effectiveness.The specific recommendations for method combinations provided in this study serve as a valuable reference for karst detection in Wuhan.

The Effect of the MNRI Method on Neurotransmitter Biomarkers of Individuals with Neurodevelopmental Disorders

Introduction: The MNRI (Masgutova Neurosensorimotor Reflex Integration) method was developed in 1989 in Russia and has spread world-wide to treat individuals with certain types reflex development deficits, behavior disorders, disorders of speech or language development, and learning disabilities. MNRI is based on techniques called “repatterning” or remodulation, meaning re-education, recoding the reflex nerve pathways specific for dynamic and postural reflex schemes. Objectives: Repatterning activates the extra pyramidal nervous system responsible for automatic mechanisms and processes, the extension of links between neurons, the growth of neural nets, myelination, and the creation of new nerve routing. This potential result was tested utilizing urinary measurements of the following neurotransmitters: epinephrine, norepinephrine, dopamine, DOPAC, serotonin, 5-HIAA, glycine, taurine, GABA, glutamate, PEA, and histamine. Methods: Neurological impact of the Masgutova Neurosensorimotor Reflex Method on the magnitude of changes in neurotransmitters was assessed by an external controlled and double-blind method using patients from one of the four diagnosis groups: 1) global developmental disorders;2) cerebral palsy, Traumatic Brain Injury (TBI), Acute Brain Injury (ABI), and seizures;3) ADD/ADHD;and 4) anxiety disorders. Results: The post-MNRI results in participants show a tendency for regulation of the above neurotransmitters resulting in their calming down, decrease of hypervigilance, stress resilience increase, improvements in behavioral and emotional regulation, positive emotions, and cognitive processes control. Conclusion: The application of the Masgutova Neurosensorimotor Reflex Method as a therapy modality offers a novelty paradigm for the treatment using neuro- and immune-modulation technologies presenting a non-pharmaceutical approach, based on use of neurosensorimotor reflex circuit concept.

High-Order Decoupled and Bound Preserving Local Discontinuous Galerkin Methods for a Class of Chemotaxis Models

In this paper,we explore bound preserving and high-order accurate local discontinuous Galerkin(LDG)schemes to solve a class of chemotaxis models,including the classical Keller-Segel(KS)model and two other density-dependent problems.We use the convex splitting method,the variant energy quadratization method,and the scalar auxiliary variable method coupled with the LDG method to construct first-order temporal accurate schemes based on the gradient flow structure of the models.These semi-implicit schemes are decoupled,energy stable,and can be extended to high accuracy schemes using the semi-implicit spectral deferred correction method.Many bound preserving DG discretizations are only worked on explicit time integration methods and are difficult to get high-order accuracy.To overcome these difficulties,we use the Lagrange multipliers to enforce the implicit or semi-implicit LDG schemes to satisfy the bound constraints at each time step.This bound preserving limiter results in the Karush-Kuhn-Tucker condition,which can be solved by an efficient active set semi-smooth Newton method.Various numerical experiments illustrate the high-order accuracy and the effect of bound preserving.

Computational Methods in the Theory of Synthesis of Radio and Acoustic Radiating Systems

A brief review of the works of the author and his co-authors on the application of nonlinear analysis, numerical and analytical methods for solving the nonlinear inverse problems (synthesis problems) for optimizing the different types of radiating systems, is presented in the paper. The synthesis problems are formulated in variational statements and further they are reduced to research and numerical solution of nonlinear integral equations of Hammerstein type. The existence theorems are proof, the investigation methods of nonuniqueness problem of solutions and numerical algorithms of finding the optimal solutions are proved.

Robustness Study and Superior Method Development and Validation for Analytical Assay Method of Atropine Sulfate in Pharmaceutical Ophthalmic Solution

Background: The robustness is a measurement of an analytical chemical method and its ability to contain unaffected by little with deliberate variation of analytical chemical method parameters. The analytical chemical method variation parameters are based on pH variability of buffer solution of mobile phase, organic ratio composition changes, stationary phase (column) manufacture, brand name and lot number variation;flow rate variation and temperature variation of chromatographic system. The analytical chemical method for assay of Atropine Sulfate conducted for robustness evaluation. The typical variation considered for mobile phase organic ratio change, change of pH, change of temperature, change of flow rate, change of column etc. Purpose: The aim of this study is to develop a cost effective, short run time and robust analytical chemical method for the assay quantification of Atropine in Pharmaceutical Ophthalmic Solution. This will help to make analytical decisions quickly for research and development scientists as well as will help with quality control product release for patient consumption. This analytical method will help to meet the market demand through quick quality control test of Atropine Ophthalmic Solution and it is very easy for maintaining (GDP) good documentation practices within the shortest period of time. Method: HPLC method has been selected for developing superior method to Compendial method. Both the compendial HPLC method and developed HPLC method was run into the same HPLC system to prove the superiority of developed method. Sensitivity, precision, reproducibility, accuracy parameters were considered for superiority of method. Mobile phase ratio change, pH of buffer solution, change of stationary phase temperature, change of flow rate and change of column were taken into consideration for robustness study of the developed method. Results: The limit of quantitation (LOQ) of developed method was much low than the compendial method. The % RSD for the six sample assay of developed method was 0.4% where the % RSD of the compendial method was 1.2%. The reproducibility between two analysts was 100.4% for developed method on the contrary the compendial method was 98.4%.

Volumetric lattice Boltzmann method for pore-scale mass diffusionadvection process in geopolymer porous structures

Porous materials present significant advantages for absorbing radioactive isotopes in nuclear waste streams.To improve absorption efficiency in nuclear waste treatment,a thorough understanding of the diffusion-advection process within porous structures is essential for material design.In this study,we present advancements in the volumetric lattice Boltzmann method(VLBM)for modeling and simulating pore-scale diffusion-advection of radioactive isotopes within geopolymer porous structures.These structures are created using the phase field method(PFM)to precisely control pore architectures.In our VLBM approach,we introduce a concentration field of an isotope seamlessly coupled with the velocity field and solve it by the time evolution of its particle population function.To address the computational intensity inherent in the coupled lattice Boltzmann equations for velocity and concentration fields,we implement graphics processing unit(GPU)parallelization.Validation of the developed model involves examining the flow and diffusion fields in porous structures.Remarkably,good agreement is observed for both the velocity field from VLBM and multiphysics object-oriented simulation environment(MOOSE),and the concentration field from VLBM and the finite difference method(FDM).Furthermore,we investigate the effects of background flow,species diffusivity,and porosity on the diffusion-advection behavior by varying the background flow velocity,diffusion coefficient,and pore volume fraction,respectively.Notably,all three parameters exert an influence on the diffusion-advection process.Increased background flow and diffusivity markedly accelerate the process due to increased advection intensity and enhanced diffusion capability,respectively.Conversely,increasing the porosity has a less significant effect,causing a slight slowdown of the diffusion-advection process due to the expanded pore volume.This comprehensive parametric study provides valuable insights into the kinetics of isotope uptake in porous structures,facilitating the development of porous materials for nuclear waste treatment applications.

等效剂量罗哌卡因和布比卡因腰麻-硬膜外联合麻醉用于Misgave-Ladach-Method剖宫产术的临床研究

目的 探讨等效剂量罗哌卡因、布比卡因腰麻-硬膜外联合麻醉用于Misgave -Ladach -Method剖宫产术的临床效能及安全性。方法 选择ASAⅠ～Ⅱ级足月妊娠初产妇80例,随机双盲法分为两组,每组各4 0例。罗哌卡因组(R组) :0 75 %罗哌卡因2ml+10 %葡萄糖液0 5ml;布比卡因组(B组) :0 75 %布比卡因1 2 5ml+10 %葡萄糖液1 2 5ml。术中麻醉效应不足时经硬膜外导管补充2 %利多卡因。术中连续监测呼吸和循环状况,评估麻醉效能,观察围手术期不良反应的发生和新生儿情况。结果 两组麻醉效能、最高阻滞平面、新生儿Apgar评分及不良反应相似(P >0 0 5 ) ,但R组起效慢,维持时间短(P <0 0 5 ) ;下肢运动阻滞程度R组显著低于B组(P <0 0 5 )。结论 等效剂量的罗哌卡因和布比卡因腰麻-硬膜外联合麻醉用于剖宫产术安全有效,与布比卡因相比,罗哌卡因对下肢运动阻滞弱且恢复迅速。

Extended Jacobian Elliptic Function Expansion Method and Its Applications in Biology

In this work, an extended Jacobian elliptic function expansion method is proposed for constructing the exact solutions of nonlinear evolution equations. The validity and reliability of the method are tested by its applications to Dynamical system in a new Double-Chain Model of DNA and a diffusive predator-prey system which play an important role in biology.

The Outpatient Burch-Sling Procedure: A Nerve-Sparing Method for Correcting Female Urinary Incontinence

Conventional methods to treat urinary stress incontinence, including the Sling, Burch, and Pereyra modification methods, are limited by several shortcomings due to disrupted nerve and vaginal wall integrity. The nerve-sparing Burch-Sling method represents a surgical advancement through the use of a nerve-sparing sling to treat genuine stress urinary incontinence. The procedure involves retropubic urethropexy using the FDA-approved Burch-Sling device. In this technique, the vagina is elevated bilaterally at the urethrovesical junction to the mid-urethra toward Cooper’s ligament above the base of the bladder. Then, the anterior vaginal wall and fascia are used as an endogenous suburethral sling without dissection. Two hundred twenty cases were included in this study;two hundred patients underwent the outpatient nerve-sparing sling method, and the other twenty underwent the novel abdominal Burch method. There were no major complications. The follow-up duration ranged from 6 months to eight years. All procedures were performed at the U.S. Women’s Institute at a 400-bed hospital in Fountain Valley, CA.

A Seismotectonic Zonation Map of Eastern Siberia: New Principles and Methods of Mapping

The paper reviews goals and objectives, stages and components of a seismotectonic study conducted in Eastern Siberia, Russia. Based on a comprehensive analysis of geological and geophysical data, our study establishes whether the local earthquakes are of tectonic origin and reveals relationships among earthquakes with recent geodynamic processes in the area under study. Seismic hazard assessment and evaluation of tectonic processes are the two major closely interrelated aspects of seismotectonic studies. A seismotectonic study is generally combined with a seismic study and conducted prior to the stage of detailed seismic zonation (DSZ) which is followed by seismic micro-zonation (SMZ). In three stages of the seismotectonic study, we analyze specific geological structures, reveal the regional dynamics of seismotectonic processes, clarify details of potential seismic hazard locations and identify sites of the potential instantaneous deformation of the crust which may take place due to active faulting. Based on results of our longterm studies, a seismotectonic zonation map of Eastern Siberia is compiled. The paper briefly reviews the methods of mapping and refers to data on active faults and neotectonic structures revealed in the area under study, which are closely related to regional earthquake sources.

Understanding roof deformation mechanics and parametric sensitivities of coal mine entries using the discrete element method

Although conventional coal mine designs are conservative regarding pillar strength,local failures such as roof-falls and pillar bursts still affect mine safety and operations.Previous studies have identified that discontinuous,layered roof materials have some self-supporting capacity.This research is a preliminary step towards understanding these mechanics in coal-measure rocks.Although others have considered broad conceptual models and simplified analogs for mine roof behavior,this study presents a unique numerical model that more completely represents in-situ roof conditions.The discrete element method(DEM)is utilized to conduct a parametric analysis considering a range of in-situ stress ratios,material properties,and joint networks to determine the parameters controlling the stability of single-entries modeled in two-dimensions.Model results are compared to empirical observations of roof-support effectiveness(ARBS)in the context of the coal mine roof rating(CMRR)system.Results such as immediate roof displacement,overall stability,and statistical relationships between model parameters and outcomes are presented herein.Potential practical applications of this line of research include:(1)roof-support optimization for a range of coal-measure rocks,(2)establishment of a relationship between roof stability and pillar stress,and(3)determination of which parameters are most critical to roof stability and therefore require concentrated evaluation.