Endoscopic treatment for pancreatic diseases:Needle-knife-guided cannulation via the minor papilla

AIM: To determine the efficacy and safety of meticulous cannulation by needle-knife.METHODS: Three needle-knife procedures were used to facilitate cannulation in cases when standard cannulation techniques failed. A total of 104 cannulationsvia the minor papilla attempted in 74 patients at our center between January 2008 and June 2014 were retrospectively reviewed.RESULTS: Standard methods were successful in79 cannulations. Of the 25 cannulations that could not be performed by standard methods, 19 were performed by needle-knife, while 17(89.5%) were successful. Needle-knife use improved the success rate of cannulation [76.0%, 79/104 vs 92.3%,(79 +17)/104; P = 0.001]. When the 6 cases not appropriate for needle-knife cannulation were excluded, the success rate was improved further(80.6%, 79/98 vs98.0%, 96/98; P = 0.000). There were no significant differences in the rates of post-endoscopic retrograde cholangiopancreatography adverse events between the group using standard methods alone and the group using needle-knife after failure of standard methods(4.7% vs 10.5%, P = 0.301).CONCLUSION: The needle-knife procedure may be an alternative method for improving the success rate of cannulation via the minor papilla, particularly when standard cannulation has failed.

Simple groups with orders 2~a3~b5~cp^d, 2~a3~b7~cp^d and 2~a3~b5~c7~d

This work deals with the power exponent 1rand 2r respectively of the maximal and second-maximal prime factors of the order of simple K4-group, and the classification for simple 4{5,7}K--group G (i.e. G can not be divided by 5 nor by 7 or ()Gp= 4 ), simple 5 -4K-group G (i.e. G can not divided by 5 and ()Gp=4) and simple 7-4K-group G (i.e. G can not divided by 7 and ()Gp= 4). It is derived that 1r =1, 2 and 4, and 2r is not greater than 4. All the simple 4K-groups with order 235,237abcdabcdpp and 2357abcd are obtained.

The Obtaining and Verification of Meticulous Climate Forecast Product

[Objective] The aim was to study the obtaining method of meticulous climate forecast product and test its forecast effect. [Method] Based on the national standard surface observation data and secondary data bank obtained by means of distance weight interpolation method, the model of climate forecast was established, and the timing, fixed-point and quantitative meticulous climate forecast of meteorological elements was obtained by using many forecast methods and artificial revision, finally the forecast effect was tested. [Result] At present, meticulous climate forecast system was used to predict the daily, five-day, ten-day, monthly, seasonal and annual variation of six meteorological elements (including average temperature, maximum temperature, minimum temperature, precipitation, average pressure and sunshine) in 10 meteorological stations in Guangzhou City. The forecast effect of meteorological elements in 10 stations in Guangzhou City from 2006 to 2010 was tested, and the average scores of monthly precipitation, average temperature, maximum temperature and minimum temperature were 75.0, 94.5, 98.6 and 88.9, respectively, while the scores of five-day meteorological elements were 77.1, 90.6, 90.1 and 82.8, which met the requirement of objective management of Guangdong Meteorological Observatory. [Conclusion] Meticulous climate forecast system could be widely used in the forecast of agricultural meteorological disasters and fixed-point forecast in large reservoir, new airport and nuclear power station.

Zhang Qing and His Meticulous Chinese Paintings

ZHANG Qing was initially drawn to the bird and flower paint-ings of the Tang and Song dynasties (7th-12th centuries). Later,Qing Dynasty (1644-1911) artist Ren Bonian, famous for hispaintings of figures, also became an important influence.Although Zhang Qing considers his style to be firmly rooted in tradi-

Study on Insulin Resistance and Genetic Polymorphisms in Essential Hypertension Patients of Two Different Kinds of TCM Constitution

Objective： To investigate the relationship of insulin resistance and the polymorphisms of insulin receptor-related genes in essential hypertension patients of two different kinds of TCM constitution. Methods： Oral glucose tolerance test （OGTT） and insulin release test （InRT） were conducted in 217 essential hypertensive patients of either sluggish meticulous （SM） constitution （139 cases） or prosperous impetuous （PI） constitution （78 cases）, and the polymorphism of three genes, including insulin-like growth factor-1 receptor （IGF-1R）, insulin receptor substrate-1 （IRS-1） and 2 （IRS-2） genes were detected. Results： （1） OGTT, InRT and insulin resistance index （Homa-IR） were higher and insulin sensitive index （ISI） was lower in the patients of SM constitution than those in patients of PI constitution. （2） Significant difference of ISI and Homa-IR was shown in patients of both constitutions with genotype G of the 3 genes. Conclusion： Decrease of insulin sensitivity and increase of insulin resistance are more obvious in hypertensive patients with genotype G of the 3 genes of SM constitution than in those of PI constitution. Therefore, the difference in constitution might be one of the genetic characteristics for insulin resistance in hypertensive patients.