An electromagnetic coupling mathematical model is established by finite element method and is verified by the contrastive experiments of copper matrix Ni-TiN cylindrical coating electrode,copper electrode and Cu50 W e...An electromagnetic coupling mathematical model is established by finite element method and is verified by the contrastive experiments of copper matrix Ni-TiN cylindrical coating electrode,copper electrode and Cu50 W electrode.The wear mechanism of Ni-TiN/Cu composite electrode in the case of high-frequency pulse current is studied,and the influence of the fluctuation frequency of discharge current on electrode wear in micro-EDM is found out.Compared with the electrode made from homogeneous material,the high frequency electromagnetic properties of Ni-TiN composite layer can be used effectively to inhibit the effect of high frequency pulse on the electrode and improve the distribution trend of current density.展开更多
Micro-gas turbine engine（MTE） rotor is an important indicator of its property, therefore, the manufacturing technology of the microminiature rotor has become a hot area of research at home and abroad. At present, th...Micro-gas turbine engine（MTE） rotor is an important indicator of its property, therefore, the manufacturing technology of the microminiature rotor has become a hot area of research at home and abroad. At present, the main manufacturing technologies of the MTE rotor are directed forming fabrication technologies. However, these technologies have a series of problems, such as complex processing technology high manufacturing cost, and low processing efficiency, and so on. This paper takes advantage of micro electric discharge machining（micro-EDM） in the field of microminiature molds manufacturing, organizes many processing technologies of micro-EDM reasonably to improve processing accuracy, presents an integrated micro-EDM technology and its process flow to fabricate MTE rotor die, and conducts a series of experiments to verify efficiency of this integrated micro-EDM. The experiments results show that the MTE rotor die has sharp outline and ensure the good consistency of MTE rotor blades. Meanwhile, the MTE rotor die is applied to micro extrusion equipment, and technologies of micro-EDM and micro forming machining are combined based on the idea of the molds manufacturing, so the MTE rotor with higher aspect ratio and better consistency of blades can be manufactured efficiently. This research presents an integrated micro-EDM technology and its process flow, which promotes the practical process of MTE effectively.展开更多
A human face with complex 3D structure is machined with a modified fix-length compensation method in this paper.The fast development of MEMS (Micro Electromechanical Systems) has strongly enhanced the application of n...A human face with complex 3D structure is machined with a modified fix-length compensation method in this paper.The fast development of MEMS (Micro Electromechanical Systems) has strongly enhanced the application of new harder work materials.As a low cost,flexible,good repeatable machining process with negligible process forces,micro-EDM milling is well suited for freeform metallic micro structures.A major problem in micro-EDM milling of complex 3D structure is the electrode wear.A new CAM system based on the UG software platform is developed in order to get good accuracy and higher efficiency.A correction coefficient is introduced and deduced for the modified fix-length compensation method.Using this method a human face with complex 3D stricter is machined successfully by micro-EDM milling.展开更多
BACKGROUND To assess the effectiveness of Shugan Jieyu capsules on peripheral blood miR-124,miR-132,and brain-derived neurotrophic factor(BDNF)levels in patients with mild to moderate depression following coronary art...BACKGROUND To assess the effectiveness of Shugan Jieyu capsules on peripheral blood miR-124,miR-132,and brain-derived neurotrophic factor(BDNF)levels in patients with mild to moderate depression following coronary artery intervention[percuta-neous coronary intervention(PCI)]for coronary heart disease.Patients with mild-to-moderate depression of the liver-qi stagnation type after PCI for coronary heart disease at the 305th Hospital of the People’s Liberation Army were enrolled from June 2022 to November 2023 and randomly assigned to two groups:Experimental(treated with Shugan Jieyu capsules)and control(tr-eated with escitalopram oxalate tablets).This study compared the antidepressant effects of these treatments using 17-item Hamilton Rating Scale for Depression(HAMD-17)scores,metabolic equivalents,low-density lipoprotein cholesterol,BDNF,high-sensitivity C-reactive protein levels,miR-124 and miR-132 levels,distribution of immune-related lymphocyte subsets,and traditional Chinese me-dicine syndrome scores before and after 6 weeks of treatment.RESULTS No significant difference was observed in any index between the two groups before treatment(P>0.05).After treatment,the total efficacy rates were 93.33%and 90.00%in the experimental and control groups,respectively.Experimental group had significantly lower scores for the main and secondary syndromes compared to the control group(P<0.05).No significant difference was observed in the metabolic equivalents between the two groups be-fore and after treatment(P>0.05).The levels of low-density lipoprotein cholesterol,high-sensitivity C-reactive pro-tein,and miR-132 were significantly lower,whereas those of miR-124,BDNF,CD3+T lymphocytes,CD3+CD4+T helper lymphocytes,and CD3+CD4+/CD3+CD8+cells were significantly higher in the experimental group com-pared to the control group(P<0.05).The incidence of adverse reactions during experimental group was signi-ficantly lower than that in control group(P<0.05).CONCLUSION Shugan Jieyu capsules have good efficacy in patients with mild-to-moderate depression after PCI,and its me-chanism may contribute to the regulation of miR-124,miR-132,BDNF levels,and lymphoid immune cells.展开更多
Micro- and nano-plastics (MNPs) are tiny plastic particles resulting from plastic product degradation. Soil MNPs have been identified as potential influential factors affecting various soil properties and crop biomass...Micro- and nano-plastics (MNPs) are tiny plastic particles resulting from plastic product degradation. Soil MNPs have been identified as potential influential factors affecting various soil properties and crop biomass productivity. This mini-review provides a synthesis of recent findings concerning their effects on soil physicochemical properties, microorganisms, organic carbon content, soil nutrients, greenhouse gas emissions, soil fauna, and their impacts on plant ecophysiology, growth, and production. The results indicate that MNPs may markedly impede soil aggregation ability, increase porosity, decrease soil bulk density, enhance water retention capacity, influence soil pH and electrical conductivity, and escalate soil water evaporation. Exposure to MNPs may predominantly induce changes in soil microbial composition, reducing the diversity and complexity of microbial communities and microbial activity while enhancing soil organic carbon stability, influencing soil nutrient dynamics, and stimulating organic carbon decomposition and denitrification processes, leading to elevated soil respiration and methane emissions, and potentially decreasing soil nitrous oxide emission. Additionally, MNPs may adversely affect soil fauna, diminish seed germination rates, promote plant root growth, yet impair plant photosynthetic efficacy and biomass productivity. These findings contribute to a better understanding of the impacts and mechanistic foundations of MNPs. Future research avenues are suggested to further explore the impacts and economic implications.展开更多
本文呈现了一个面向电火花加工的多轴数控系统的设计与实现。基于OSEC(open system environment for controller)标准的数控系统开放式结构设计思想,在分析电火花加工工艺和控制功能的基础上,构建了电火花数控系统的分层体系结构,根据...本文呈现了一个面向电火花加工的多轴数控系统的设计与实现。基于OSEC(open system environment for controller)标准的数控系统开放式结构设计思想,在分析电火花加工工艺和控制功能的基础上,构建了电火花数控系统的分层体系结构,根据任务的功能特性把控制系统划分成功能模块,通过功能模块配置和系统配置,实现不同加工对象的应用软件。同时介绍了电火花专用四轴运动控制器的设计,该控制器采用单片微处理器和专用运动控制芯片组成的双CPU结构,利用PCI总线接口芯片和共享内存实现与上下位机之间的高速通信。该控制系统经实际运行证明,性能稳定可靠,满足电火花数控加工的功能要求。展开更多
基金the National Natural Science Foundation of China for financially supporting this research through project No.51005027
文摘An electromagnetic coupling mathematical model is established by finite element method and is verified by the contrastive experiments of copper matrix Ni-TiN cylindrical coating electrode,copper electrode and Cu50 W electrode.The wear mechanism of Ni-TiN/Cu composite electrode in the case of high-frequency pulse current is studied,and the influence of the fluctuation frequency of discharge current on electrode wear in micro-EDM is found out.Compared with the electrode made from homogeneous material,the high frequency electromagnetic properties of Ni-TiN composite layer can be used effectively to inhibit the effect of high frequency pulse on the electrode and improve the distribution trend of current density.
基金Supported by National Basic Research Program of China(973 Program,Grant No.2012CB934102)National Natural Science Foundation of China(Grant No.50835002)National Science Foundation for Young Scientists of China(Grant No.51105111)
文摘Micro-gas turbine engine（MTE） rotor is an important indicator of its property, therefore, the manufacturing technology of the microminiature rotor has become a hot area of research at home and abroad. At present, the main manufacturing technologies of the MTE rotor are directed forming fabrication technologies. However, these technologies have a series of problems, such as complex processing technology high manufacturing cost, and low processing efficiency, and so on. This paper takes advantage of micro electric discharge machining（micro-EDM） in the field of microminiature molds manufacturing, organizes many processing technologies of micro-EDM reasonably to improve processing accuracy, presents an integrated micro-EDM technology and its process flow to fabricate MTE rotor die, and conducts a series of experiments to verify efficiency of this integrated micro-EDM. The experiments results show that the MTE rotor die has sharp outline and ensure the good consistency of MTE rotor blades. Meanwhile, the MTE rotor die is applied to micro extrusion equipment, and technologies of micro-EDM and micro forming machining are combined based on the idea of the molds manufacturing, so the MTE rotor with higher aspect ratio and better consistency of blades can be manufactured efficiently. This research presents an integrated micro-EDM technology and its process flow, which promotes the practical process of MTE effectively.
基金Funded by the National Natural Science Foundation of China (No.50635040)
文摘A human face with complex 3D structure is machined with a modified fix-length compensation method in this paper.The fast development of MEMS (Micro Electromechanical Systems) has strongly enhanced the application of new harder work materials.As a low cost,flexible,good repeatable machining process with negligible process forces,micro-EDM milling is well suited for freeform metallic micro structures.A major problem in micro-EDM milling of complex 3D structure is the electrode wear.A new CAM system based on the UG software platform is developed in order to get good accuracy and higher efficiency.A correction coefficient is introduced and deduced for the modified fix-length compensation method.Using this method a human face with complex 3D stricter is machined successfully by micro-EDM milling.
基金the 305 Hospital Independent Scientific Research Fund,2024,No.24ZZJJLW-022.
文摘BACKGROUND To assess the effectiveness of Shugan Jieyu capsules on peripheral blood miR-124,miR-132,and brain-derived neurotrophic factor(BDNF)levels in patients with mild to moderate depression following coronary artery intervention[percuta-neous coronary intervention(PCI)]for coronary heart disease.Patients with mild-to-moderate depression of the liver-qi stagnation type after PCI for coronary heart disease at the 305th Hospital of the People’s Liberation Army were enrolled from June 2022 to November 2023 and randomly assigned to two groups:Experimental(treated with Shugan Jieyu capsules)and control(tr-eated with escitalopram oxalate tablets).This study compared the antidepressant effects of these treatments using 17-item Hamilton Rating Scale for Depression(HAMD-17)scores,metabolic equivalents,low-density lipoprotein cholesterol,BDNF,high-sensitivity C-reactive protein levels,miR-124 and miR-132 levels,distribution of immune-related lymphocyte subsets,and traditional Chinese me-dicine syndrome scores before and after 6 weeks of treatment.RESULTS No significant difference was observed in any index between the two groups before treatment(P>0.05).After treatment,the total efficacy rates were 93.33%and 90.00%in the experimental and control groups,respectively.Experimental group had significantly lower scores for the main and secondary syndromes compared to the control group(P<0.05).No significant difference was observed in the metabolic equivalents between the two groups be-fore and after treatment(P>0.05).The levels of low-density lipoprotein cholesterol,high-sensitivity C-reactive pro-tein,and miR-132 were significantly lower,whereas those of miR-124,BDNF,CD3+T lymphocytes,CD3+CD4+T helper lymphocytes,and CD3+CD4+/CD3+CD8+cells were significantly higher in the experimental group com-pared to the control group(P<0.05).The incidence of adverse reactions during experimental group was signi-ficantly lower than that in control group(P<0.05).CONCLUSION Shugan Jieyu capsules have good efficacy in patients with mild-to-moderate depression after PCI,and its me-chanism may contribute to the regulation of miR-124,miR-132,BDNF levels,and lymphoid immune cells.
文摘Micro- and nano-plastics (MNPs) are tiny plastic particles resulting from plastic product degradation. Soil MNPs have been identified as potential influential factors affecting various soil properties and crop biomass productivity. This mini-review provides a synthesis of recent findings concerning their effects on soil physicochemical properties, microorganisms, organic carbon content, soil nutrients, greenhouse gas emissions, soil fauna, and their impacts on plant ecophysiology, growth, and production. The results indicate that MNPs may markedly impede soil aggregation ability, increase porosity, decrease soil bulk density, enhance water retention capacity, influence soil pH and electrical conductivity, and escalate soil water evaporation. Exposure to MNPs may predominantly induce changes in soil microbial composition, reducing the diversity and complexity of microbial communities and microbial activity while enhancing soil organic carbon stability, influencing soil nutrient dynamics, and stimulating organic carbon decomposition and denitrification processes, leading to elevated soil respiration and methane emissions, and potentially decreasing soil nitrous oxide emission. Additionally, MNPs may adversely affect soil fauna, diminish seed germination rates, promote plant root growth, yet impair plant photosynthetic efficacy and biomass productivity. These findings contribute to a better understanding of the impacts and mechanistic foundations of MNPs. Future research avenues are suggested to further explore the impacts and economic implications.
文摘本文呈现了一个面向电火花加工的多轴数控系统的设计与实现。基于OSEC(open system environment for controller)标准的数控系统开放式结构设计思想,在分析电火花加工工艺和控制功能的基础上,构建了电火花数控系统的分层体系结构,根据任务的功能特性把控制系统划分成功能模块,通过功能模块配置和系统配置,实现不同加工对象的应用软件。同时介绍了电火花专用四轴运动控制器的设计,该控制器采用单片微处理器和专用运动控制芯片组成的双CPU结构,利用PCI总线接口芯片和共享内存实现与上下位机之间的高速通信。该控制系统经实际运行证明,性能稳定可靠,满足电火花数控加工的功能要求。
