Highly Sensitive Chemiluminescence Detection for PDMS/GIass Micro-chip Electrophoresis

This paper described a highly sensitive chemiluminescence detection system for micro-chip electrophoresis (MCE) based on luminol-hydrogen peroxide reaction catalyzed by the metal ions. The micro-chip was composed of poly(dimethylsiloxane) (PDMS) and glass, and was fabricated by micro-machining technology. The surface of channels was dynamically modified by polydimethylacrylamide (PDMA) in order to eliminate unhomogeneous electroosmotic flow (EOF) of the PDMS/glass chip, adsorption of molecules, and improve hydrophobicity on PDMS surface. The detection modes, reagent mix procedures and reaction conditions were optimized and the detection limit of 5×10 mol/L for cobalt (II) was achieved by MCE with chemiluminescence detection, which was about four orders of magnitude more sensitive than that reported in the reference.

微小元器件（Micro-chip）表面贴装技术

微小元器件（Micro-chip）指的是封装尺寸小于0402的片状表面贴装器件（SMD），即0201或01005。本文介绍了成功实现微小元器件表面贴装所面临的挑战及工艺条件，供大家参考。