Grindability Evaluation of Ultrasonic Assisted Grinding of Silicon Nitride Ceramic Using Minimum Quantity Lubrication Based SiO_(2)Nanofluid

Minimum quantity Lubrication(MQL)is a sustainable lubrication system that is famous in many machining systems.It involve the spray of an infinitesimal amount of mist-like lubricants during machining processes.The MQL system is affirmed to exhibit an excellent machining performance,and it is highly economical.The nanofluids are understood to exhibit excellent lubricity and heat evacuation capability,compared to pure oil-based MQL system.Studies have shown that the surface quality and amount of energy expended in the grinding operations can be reduced considerably due to the positive effect of these nanofluids.This work presents an experimental study on the tribological performance of SiO_(2)nanofluid during grinding of Si_(3)N_(4)ceramic.The effect different grinding modes and lubrication systems during the grinding operation was also analyzed.Different concentrations of the SiO_(2)nanofluid was manufactured using canola,corn and sunflower oils.The quantitative evaluation of the grinding process was done based on the amount of grinding forces,specific grinding energy,frictional coefficient,and surface integrity.It was found that the canola oil exhibits optimal lubrication performance compared to corn oil,sunflower oil,and traditional lubrication systems.Additionally,the introduction of ultrasonic vibrations with the SiO_(2)nanofluid in MQL system was found to reduce the specific grinding energy,normal grinding forces,tangential grinding forces,and surface roughness by 65%,57%,65%,and 18%respectively.Finally,regression analysis was used to obtain an optimum parameter combinations.The observations from this work will aid the smooth transition towards ecofriendly and sustainable machining of engineering ceramics.

Damage evolution and removal behaviors of GaN crystals involved in double-grits grinding

Elucidating the complex interactions between the work material and abrasives during grinding of gallium nitride(GaN)single crystals is an active and challenging research area.In this study,molecular dynamics simulations were performed on double-grits interacted grinding of GaN crystals;and the grinding force,coefficient of friction,stress distribution,plastic damage behaviors,and abrasive damage were systematically investigated.The results demonstrated that the interacted distance in both radial and transverse directions achieved better grinding quality than that in only one direction.The grinding force,grinding induced stress,subsurface damage depth,and abrasive wear increase as the transverse interacted distance increases.However,there was no clear correlation between the interaction distance and the number of atoms in the phase transition and dislocation length.Appropriate interacted distances between abrasives can decrease grinding force,coefficient of friction,grinding induced stress,subsurface damage depth,and abrasive wear during the grinding process.The results of grinding tests combined with cross-sectional transmission electron micrographs validated the simulated damage results,i.e.amorphous atoms,high-pressure phase transition,dislocations,stacking faults,and lattice distortions.The results of this study will deepen our understanding of damage accumulation and material removal resulting from coupling between abrasives during grinding and can be used to develop a feasible approach to the wheel design of ordered abrasives.

Towards Sustainable Grinding of Difficult-to-Cut Alloys-A Holistic Review and Trends

Grinding,a critical precision machining process for difficult-to-cut alloys,has undergone continual technological advancements to improve machining efficiency.However,the sustainability of this process is gaining heightened attention due to significant challenges associated with the substantial specific grinding energy and the extensive heat generated when working with difficult-to-cut alloys,renowned for their exceptional physical and mechanical properties.In response to these challenges,the widespread application of massive coolant in manufacturing industries to dissipate grinding heat has led to complex post-cleaning and disposal processes.This,in turn,has resulted in issues such as large energy consumption,a considerable carbon footprint,and concerns related to worker health and safety,which have become the main factors that restrict the development of grinding technology.This paper provides a holistic review of sustainability in grinding difficult-to-cut alloys,encompassing current trends and future directions.The examination extends to developing grinding technologies explicitly tailored for these alloys,comprehensively evaluating their sustainability performance.Additionally,the exploration delves into innovative sustainable technologies,such as heat pipe/oscillating heat pipe grinding wheels,minimum quantity lubrication,cryogenic cooling,and others.These groundbreaking technologies aim to reduce dependence on hazardous coolants,minimizing energy and resource consumption and carbon emissions associated with coolant-related or subsequent disposal processes.The essence of these technologies lies in their potential to revolutionize traditional grinding practices,presenting environmentally friendly alternatives.Finally,future development trends and research directions are put forward to pursue the current limitation of sustainable grinding for difficult-to-cut alloys.This paper can guide future research and development efforts toward more environmentally friendly grinding operations by understanding the current state of sustainable grinding and identifying emerging trends.

Effects of Different Grinding Methods on the Quality of Soybean Bean Milk

[Objectives] This study was conducted to improve the nutritional value of soybean milk, enrich the variety and taste of soybean milk, and find healthy food that is more conducive to people s nutritional needs. [Methods] Whole soybean milk was prepared by grinding with a grinding wheel at a low concentration (low-concentration grinding) and a stainless steel mill at a high concentration (high-concentration grinding). The sensory, physical and chemical characteristics and anti-nutritional factors of whole soybean milk produced by different grinding methods were studied. [Results] Compared with low-concentration grinding, the protein content in soybean milk prepared by high-concentration grinding increased by 24%, and the dietary fiber content increased by 74.7%. Before and after high-pressure homogenization, the particle size D(4, 3) of soybean milk prepared by low-concentration grinding was 212.1 and 93.59 μm, respectively, and the particle size D(4, 3) of soybean milk prepared by high-concentration grinding was 134.0 and 64.64 μm, respectively. The trypsin inhibitor activity and phytic acid content of soybean milk prepared by high-concentration grinding were significantly lower than those of soybean milk prepared by low-concentration grinding. [Conclusions] This study improves the diet structure of the broad masses of people, strengthens people s physique, and provides a new idea for the implementation and development of China s "Soybean Action Programme".

Two-stage extraction by partial grinding of impacted mandibular third molar in close proximity to the inferior alveolar nerve

BACKGROUND Extraction of impacted third molars often leads to severe complications caused by damage to the inferior alveolar nerve(IAN).AIM To proposes a method for the partial grinding of an impacted mandibular third molar(IMM3)near the IAN to prevent IAN injury during IMM3 extraction.METHODS Between January 1996 and March 2022,25 patients with IMM3 roots near the IAN were enrolled.The first stage of the operation consisted of grinding a major part of the IMM3 crown with a high-speed turbine dental drill to achieve sufficient space between the mandibular second molar and IMM3.After 6 months,when the root tips were observed to be away from the IAN on X-ray examination,the remaining part of the IMM3 was completely removed.RESULTS All IMM3s were extracted easily without symptoms of IAN injury after extraction.CONCLUSION Partial IMM3 grinding may be a good alternative treatment option to avoid IAN injury in high-risk cases.

Contact Mechanism of Rail Grinding with Open-Structured Abrasive Belt Based on Pressure Grinding Plate

The current research of abrasive belt grinding rail mainly focuses on the contact mechanism and structural design.Compared with the closed structure abrasive belt grinding,open-structured abrasive belt grinding has excellent performance in dynamic stability,consistency of grinding quality,extension of grinding mileage and improvement of working efficiency.However,in the contact structure design,the open-structured abrasive belt grinding rail using a profiling pressure grinding plate and the closed structure abrasive belt using the contact wheel are different,and the contact mechanisms of the two are different.In this paper,based on the conformal contact and Hertz theory,the contact mechanism of the pressure grinding plate,abrasive belt and rail is analyzed.Through finite element simulation and static pressure experiment,the contact behavior of pressure grinding plate,abrasive belt and rail under single concentrated force,uniform force and multiple concentrated force was studied,and the distribution characteristics of contact stress on rail surface were observed.The results show that under the same external load,there are three contact areas under the three loading modes.The outer contour of the middle contact area is rectangular,and the inner contour is elliptical.In the contact area at both ends,the stress is extremely small under a single concentrated force,the internal stress is drop-shaped under a uniform force,and the internal stress under multiple concentration forces is elliptical.Compared with the three,the maximum stress is the smallest and the stress distribution is more uniform under multiple concentrated forces.Therefore,the multiple concentrated forces is the best grinding pressure loading mode.The research provides support for the application of rail grinding with open-structured abrasive belt based on pressure grinding plate,such as contact mechanism and grinding pressure mode selection.

Tribological Mechanism of Graphene and Ionic Liquid Mixed Fluid on Grinding Interface under Nanofluid Minimum Quantity Lubrication

Graphene has superhigh thermal conductivity up to 5000 W/(m·K),extremely thin thickness,superhigh mechanical strength and nano-lamellar structure with low interlayer shear strength,making it possess great potential in mini-mum quantity lubrication(MQL)grinding.Meanwhile,ionic liquids(ILs)have higher thermal conductivity and better thermal stability than vegetable oils,which are frequently used as MQL grinding fluids.And ILs have extremely low vapor pressure,thereby avoiding film boiling in grinding.These excellent properties make ILs also have immense potential in MQL grinding.However,the grinding performance of graphene and ionic liquid mixed fluid under nano-fluid minimum quantity lubrication(NMQL),and its tribological mechanism on abrasive grain/workpiece grinding interface,are still unclear.This research firstly evaluates the grinding performance of graphene and ionic liquid mixed nanofluids(graphene/IL nanofluids)under NMQL experimentally.The evaluation shows that graphene/IL nanofluids can further strengthen both the cooling and lubricating performances compared with MQL grinding using ILs only.The specific grinding energy and grinding force ratio can be reduced by over 40%at grinding depth of 10μm.Work-piece machined surface roughness can be decreased by over 10%,and grinding temperature can be lowered over 50℃at grinding depth of 30μm.Aiming at the unclear tribological mechanism of graphene/IL nanofluids,molecular dynamics simulations for abrasive grain/workpiece grinding interface are performed to explore the formation mechanism of physical adsorption film.The simulations show that the grinding interface is in a boundary lubrication state.IL molecules absorb in groove-like fractures on grain wear flat face to form boundary lubrication film,and graphene nanosheets can enter into the grinding interface to further decrease the contact area between abrasive grain and workpiece.Compared with MQL grinding,the average tangential grinding force of graphene/IL nanofluids can decrease up to 10.8%.The interlayer shear effect and low interlayer shear strength of graphene nanosheets are the principal causes of enhanced lubricating performance on the grinding interface.EDS and XPS analyses are further carried out to explore the formation mechanism of chemical reaction film.The analyses show that IL base fluid happens chemical reactions with workpiece material,producing FeF_(2),CrF_(3),and BN.The fresh machined surface of workpiece is oxidized by air,producing NiO,Cr_(2)O_(3) and Fe_(2)O_(3).The chemical reaction film is constituted by fluorides,nitrides and oxides together.The combined action of physical adsorption film and chemical reaction film make graphene/IL nano-fluids obtain excellent grinding performance.

Temperature field model in surface grinding: a comparative assessment

Grinding is a crucial process in machining workpieces because it plays a vital role in achieving the desired precision and surface quality.However,a significant technical challenge in grinding is the potential increase in temperature due to high specific energy,which can lead to surface thermal damage.Therefore,ensuring control over the surface integrity of workpieces during grinding becomes a critical concern.This necessitates the development of temperature field models that consider various parameters,such as workpiece materials,grinding wheels,grinding parameters,cooling methods,and media,to guide industrial production.This study thoroughly analyzes and summarizes grinding temperature field models.First,the theory of the grinding temperature field is investigated,classifying it into traditional models based on a continuous belt heat source and those based on a discrete heat source,depending on whether the heat source is uniform and continuous.Through this examination,a more accurate grinding temperature model that closely aligns with practical grinding conditions is derived.Subsequently,various grinding thermal models are summarized,including models for the heat source distribution,energy distribution proportional coefficient,and convective heat transfer coefficient.Through comprehensive research,the most widely recognized,utilized,and accurate model for each category is identified.The application of these grinding thermal models is reviewed,shedding light on the governing laws that dictate the influence of the heat source distribution,heat distribution,and convective heat transfer in the grinding arc zone on the grinding temperature field.Finally,considering the current issues in the field of grinding temperature,potential future research directions are proposed.The aim of this study is to provide theoretical guidance and technical support for predicting workpiece temperature and improving surface integrity.

Formation of quaternary all-d-metal Heusler alloy by Co doping fcc type Ni_(2)MnV and mechanical grinding induced B2–fcc transformation

The structure of the all-d-metal alloy Ni_(50-x)Co_(x)Mn_(25)V_(25)(x=0–50)is investigated by using theoretical and experimental methods.The first-principles calculations indicate that the most stable structure of the Ni_2MnV alloy is face-centered cubic (fcc)type structure with ferrimagnetic state and the equilibrium lattice constant is 3.60A,which is in agreement with the experimental result.It is remarkable that replacing partial Ni with Co can turn the alloy from the fcc structure to the B2-type Heusler structure as Co content x>37 by using the melting spinning method,implying that the d–d hybridization between Co/Mn elements and low-valent elements V stabilizes the Heusler structure.The Curie temperature T_(C) of all-dmetal Heuser alloy Ni_(50-x)Co_(x)Mn_(25)V_(25)(x>37)increases almost linearly with the increase of Co due to that the interaction of Co–Mn is stronger than that of Ni–Mn.A magnetic transition from ferromagnetic state to weak magnetic state accompanying with grinding stress induced transformation from B2 to the dual-phase of B2 and fcc has been observed in these all-d-metal Heusler alloys.This phase transformation and magnetic change provide a guide to overcome the brittleness and make the all-d-metal Heusler alloy interesting in stress and magnetic driving structural transition.

Multi-Objective Optimization for an Industrial Grinding and Classification Process Based on PBM and RSM

The grinding and classification process is one of the key sub-processes in mineral processing, which influences the final process indexes significantly and determines energy and ball consumption of the whole plant. Therefore, optimal control of the process has been very important in practice. In order to stabilize the grinding index and improve grinding capacity in the process,a process model based on population balance model(PBM) is calibrated in this study. The correlation between the mill power and the operating variables in the grinding process is modelled by using the response surface method(RSM), which solves the problem where the traditional power modeling method relies on some unobservable mechanism-related parameters. On this basis, a multi-objective optimization model is established to maximize the useful power of the grinding circuit to improve the throughput of the grinding operation and improve the fraction of –0.074 mm particles in the hydrocyclone overflow to smooth the subsequent flotation operation. The elite non-dominated sorting genetic algorithm-II(NSGA-II) is then employed to solve the multi-objective optimization problem. Finally, subjective and objective weighting methods and integrated multi-attribute decision-making methods are used to select the optimal solution on the Pareto optimal solution set. The results demonstrate that the throughput of the mill and the fraction of –0.074 mm particles in the overflow of the cyclone are increased by 3.83 t/h and 2.53%, respectively.

On Energy Assessment of Titanium Alloys Belt Grinding Involving Abrasive Wear Effects

Improved energy utilisation,precision,and quality are critical in the current trend of low-carbon green manufactur-ing.In this study,three abrasive belts were prepared at various wear stages and characterised quantitatively.The effects of abrasive belt wear on the specific grinding energy partition were investigated by evaluating robotic belt grinding of titanium plates.A specific grinding energy model based on subdivided tangential forces of cutting and sliding was developed for investigating specific energy and energy utilisation coefficient EUC.The surface mor-phology and Abbott–Firestone curves of the belts were introduced to analyse the experimental findings from the per-spective of the micro cutting behaviour.The specific grinding energy increased with abrasive belt wear,especially when the belt was near the end of its life.Moreover,the belt wear could lead to a predominance change of sliding and chip formation energy.The highest EUC was observed in the middle of the belt life because of its retained sharp cutting edge and uniform distribution of the grit protrusion height.This study provides guidance for balancing the energy consumption and energy utilization efficiency of belt grinding.

Prediction of Grinding Force by an Electroplated Grinding Wheel with Orderly-Micro-Grooves

The ability to predict a grinding force is important to control,monitor,and optimize the grinding process.Few theoretical models were developed to predict grinding forces when a structured wheel was used in a grinding process.This paper aimed to establish a single-grit cutting force model to predict the ploughing,friction and cutting forces in a grinding process.It took into the consideration of actual topography of the grinding wheel,and a theoretical grinding force model for grinding hardened AISI 52100 by the wheel with orderly-micro-grooves was proposed.The model was innovative in the sense that it represented the random thickness of undeformed chips by a probabilistic expression,and it reflected the microstructure characteristics of the structured wheel explicitly.Note that the microstructure depended on the randomness of the protruding heights and distribution density of the grits over the wheel.The proposed force prediction model was validated by surface grinding experiments,and the results showed(1)a good agreement of the predicted and measured forces and(2)a good agreement of the changes of the grinding forces along with the changes of grinding parameters in the prediction model and experiments.This research proposed a theoretical grinding force model of an electroplated grinding wheel with orderly-micro-grooves which is accurate,reliable and effective in predicting grinding forces.

Grinding Characteristics of MoS_(2)-Coated Brazed CBN Grinding Wheels in Dry Grinding of Titanium Alloy

As an important green manufacturing process,dry grinding has problems such as high grinding temperature and insufficient cooling capacity.Aiming at the problems of sticking and burns in dry grinding of titanium alloys,grinding performance evaluation of molybdenum disulfide(MoS_(2))solid lubricant coated brazed cubic boron carbide(CBN)grinding wheel(MoS_(2)-coated CBN wheel)in dry grinding titanium alloys was carried out.The lubrication mechanism of MoS_(2)in the grinding process is analyzed,and the MoS_(2)-coated CBN wheel is prepared.The results show that the MoS_(2)solid lubricant can form a lubricating film on the ground surface and reduce the friction coefficient and grinding force.Within the experimental parameters,normal grinding force decreased by 42.5%,and tangential grinding force decreased by 28.1%.MoS_(2)lubricant can effectively improve the heat dissipation effect of titanium alloy grinding arc area.Compared with common CBN grinding wheel,MoS_(2)-coated CBN wheel has lower grinding temperature.When the grinding depth reaches 20μm,the grinding temperature decreased by 30.5%.The wear of CBN grains of grinding wheel were analyzed by mathematical statistical method.MoS_(2)lubricating coating can essentially decrease the wear of grains,reduce the adhesion of titanium alloy chip,prolong the service life of grinding wheel,and help to enhance the surface quality of workpiece.This research provides high-quality and efficient technical support for titanium alloy grinding.

Enhanced Heat Transfer Technology Based on Emission Reduction and Carbon Reduction in Cutting and Grinding

Huge carbon emissions in machining process,which characterized by high energy consumption and usage of non-renewable resources,is becoming an obsession in the past decades.In the face of the international strategy of carbon peak,it is imperative to eliminate the usage of mineral cutting fluids and reduce energy consumption and carbon emissions by green cutting/grinding technologies,such as dry cutting,minimum quantity lubrication(MQL).

Vision Sensing-Based Online Correction System for Robotic Weld Grinding

The service cycle and dynamic performance of structural parts are afected by the weld grinding accuracy and surface consistency. Because of reasons such as assembly errors and thermal deformation, the actual track of the robot does not coincide with the theoretical track when the weld is ground ofine, resulting in poor workpiece surface quality. Considering these problems, in this study, a vision sensing-based online correction system for robotic weld grinding was developed. The system mainly included three subsystems: weld feature extraction, grinding, and robot real-time control. The grinding equipment was frst set as a substation for the robot using the WorkVisual software. The input/output (I/O) ports for communication between the robot and the grinding equipment were confgured via the I/O mapping function to enable the robot to control the grinding equipment (start, stop, and speed control). Subsequently, the Ethernet KRL software package was used to write the data interaction structure to realize realtime communication between the robot and the laser vision system. To correct the measurement error caused by the bending deformation of the workpiece, we established a surface profle model of the base material in the weld area using a polynomial ftting algorithm to compensate for the measurement data. The corrected extracted weld width and height errors were reduced by 2.01% and 9.3%, respectively. Online weld seam extraction and correction experiments verifed the efectiveness of the system’s correction function, and the system could control the grinding trajectory error within 0.2 mm. The reliability of the system was verifed through actual weld grinding experiments. The roughness, Ra, could reach 0.504 µm and the average residual height was within 0.21 mm. In this study, we developed a vision sensing-based online correction system for robotic weld grinding with a good correction efect and high robustness.

Allowance Extraction Considering of Inner and Outer Contour and Experimental Research on Belt Grinding of Hollow Blade

Aero-engine fan blades of ten use a cavity structure to improve the thrust-to-weight ratio of the aircraft.However,the use of the cavity structure brings a series of difficulties to the manufacturing and processing of the blades.Due to the limitation of blade manufacturing technology,it is difficult for the internal cavity structure to achieve the designed contour shape,so the blade has uneven wall thickness and poor consistency,which affects the fatigue performance and airflow dynamic performance of the blade.In order to reduce the influence of uneven wall thickness,this paper proposes a grinding allowance extraction method considering the double dimension constraints(DDC)of the inner and outer contours of the hollow blade.Constrain the two dimensions of the inner and outer contours of the hollow blade.On the premise of satisfying the outer contour constraints,the machining model of the blade is modified according to the distribution of the inwall contour to obtain a more reasonable distribution of the grinding allowance.On the premise of satisfying the contour constraints,according to the distribution of the inwall contour,the machining model of the blade is modified to obtain a more reasonable distribution of the grinding allowance.Through the grinding experiment of the hollow blade,the surface roughness is below Ra0.4μm,and the contour accuracy is between-0.05~0.14 mm,which meets the processing requirements.Compared with the allowance extraction method that only considers the contour,the problem of poor wall thickness consistency can be effectively improved.It can be used to extract the allowance of aero-engine blades with hollow features,which lays a foundation for the study of hollow blade grinding methods with high service performance.

Resonance and Bifurcation of Fractional Nonlinear Systems with Power Damping Term for Robot Grinding

A fractional nonlinear system with power damping term is introduced to study the forced vibration system in order to solve the resonance and bifurcation problems between grinding wheel and steel bar during robot grinding.The robot,grinding wheel and steel bar are reduced to a spring-damping second-order system model.The implicit function equations of vibration amplitude of the dynamic system with coulomb friction damping,linear damping,square damping and cubic damping are obtained by average method.The stability of the system is analyzed and explained,and the stability condition of the system is proposed.Then,the amplitude-frequency characteristic curves of the system under different fractional differential orders,nonlinear stiffness parameters,fractional differential term coefficients and external excitation amplitude are analyzed.It is shown that the fractional differential term in the dynamic system is the damping characteristic.Then the influence of four kinds of damping on the vibration amplitude of the system under the same parameter is investigated and it is proved that the cubic damping suppresses the vibration of the system to the maximum extent.Finally,based on the idea that the equilibrium point of the system is the constant part of the Fourier series expansion term,the bifurcation behavior caused by the change of damping parameters in linear damping,square damping and cubic damping systems with different values of fractional differential order is investigated.

Material Removal Mechanism and Force Modeling in Ultrasonic Vibration-Assisted Micro-Grinding Biological Bone

Micro-grinding with a spherical grinding head has been deemed an indispensable method in high-risk surgeries, such as neurosurgery and spine surgery, where bone grinding has long been plagued by the technical bottleneck of mechanical stress-induced crack damage. In response to this challenge, the ultrasound-assisted biological bone micro-grinding novel process with a spherical grinding head has been proposed by researchers. Force modeling is a prerequisite for process parameter determination in orthopedic surgery, and the difculty in establishing and accurately predicting bone micro-grinding force prediction models is due to the geometric distribution of abrasive grains and the dynamic changes in geometry and kinematics during the cutting process. In addressing these critical needs and technical problems, the shape and protrusion heights of the wear particle of the spherical grinding head were frst studied, and the gradual rule of the contact arc length under the action of high-speed rotating ultrasonic vibration was proposed. Second, the mathematical model of the maximum thickness of undeformed chips under ultrasonic vibration of the spherical grinding head was established. Results showed that ultrasonic vibration can reduce the maximum thickness of undeformed chips and increase the range of ductile and bone meal removals, revealing the mechanism of reducing grinding force. Further, the dynamic grinding behavior of diferent layers of abrasive particles under diferent instantaneous interaction states was studied. Finally, a prediction model of micro-grinding force was established in accordance with the relationship between grinding force and cutting depth, revealing the mechanism of micro-grinding force transfer under ultrasonic vibration. The theoretical model’s average deviations are 10.37% in x-axis direction, 6.85% in y-axis direction, and 7.81% in z-axis direction compared with the experimental results. This study provides theoretical guidance and technical support for clinical bone micro-grinding.

Evaluating the Effects of Crystallinity on Drug Release Behaviour in Itraconazole- or Miconazole-Loaded PLGA Microparticles Prepared Using a Co-Grinding Method

This study aimed to prepare and characterize itraconazole (ITCZ)- or miconazole (MCZ)-loaded poly (lactide-co-glycolide) (PLGA) microparticles (MP) using a co-grinding method with ball milling, which is a solvent-free and convenient procedure. PLGA MP was prepared by grinding for 60 min, and the fixed theoretical drug loading was set at 9.1% and 16.7% for both drugs. The obtained loading efficiency for both drugs was estimated to be approximately 100%. The average diameters of the drug-loaded PLGA MP were approximately 20 - 35 μm. Powder X-ray diffraction (PXRD) or differential scanning calorimetry (DSC) confirmed amorphization of ITCZ and MCZ in ITCZ- or MCZ-loaded PLGA MP in all formulations. The drug release percentage from 9.1%-loaded ITCZ-PLGA7505 MP at 24 h was almost 50%, which was higher than that of ITCZ powder. The drug release percentage from MCZ-loaded PLGA7505 MP at 4 h was over 80%, which was higher than that of MCZ powder. This enhancement of release rate is caused by the amorphization of ITCZ or MCZ in the PLGA matrix. MCZ-loaded PLGA7510 MP showed a sustained release profile up to 24 h, suggesting that MCZ exists in an amorphous form in the PLGA matrix;however, the release rate declined owing to the large molecular weight of PLGA. Therefore, the release enhancement of antifungal drugs loaded on PLGA MP could be achieved by their amorphization using a co-grinding method with ball milling.

THERMAL STUDY ON THE GRINDING OF GRANITE WITH SUPERABRASIVE TOOLS

In the present paer, a thermal study was conducted for the grinding of granite with diamond tools. Three types of grinding-straight surface grinding, deep grinding(circular sawing), and vertical spindle grinding-were studied. Some surface grinding tests were also conducted using a CBN(cubic boron nitride) wheel. Temperature distributions on the workpiece surface were measured using a foil thermocouple and the energy partition to the workpiece was estimated using a temperature matching method. The temperature for CBN surface grinding was found to be much higher than for diamond grinding. Energy partitions to the granite were 30%～36% for CBN surface grinding, 25%～32% for diamond surface grinding, about 53% for vertical spindle grinding, and 5.5%～9% for diamond deep grinding. The low energy partition value in deep grinding also suggested that more of the heat generated by grinding in this case can be conducted to the grinding tool and promote tool wear.