Twenty 2,3-disubstituted-4(3H)-quinazolinones were synthesed by one-pot three-component method with isa- toic anhydride, orthoesters and amines as raw materials in the presence of KAI(SO4)2·12H2O (Alum) und...Twenty 2,3-disubstituted-4(3H)-quinazolinones were synthesed by one-pot three-component method with isa- toic anhydride, orthoesters and amines as raw materials in the presence of KAI(SO4)2·12H2O (Alum) under micro- wave irradiation and solvent-free conditions. 6-Bromo-2-propyl-3-p-tolylquinazolin-4(3H)-one (4m), 6-bromo-2- methyl-3-phenethylquinazolin-4(3H)-one (4n) and 6-bromo-2-ethyl-3-phenethylquinazolin-4(3H)-one (40) were characterized by IR, 1H NMR, 13C NMR and elemental analysis.展开更多
文摘Twenty 2,3-disubstituted-4(3H)-quinazolinones were synthesed by one-pot three-component method with isa- toic anhydride, orthoesters and amines as raw materials in the presence of KAI(SO4)2·12H2O (Alum) under micro- wave irradiation and solvent-free conditions. 6-Bromo-2-propyl-3-p-tolylquinazolin-4(3H)-one (4m), 6-bromo-2- methyl-3-phenethylquinazolin-4(3H)-one (4n) and 6-bromo-2-ethyl-3-phenethylquinazolin-4(3H)-one (40) were characterized by IR, 1H NMR, 13C NMR and elemental analysis.