For decades,manufacturers have boasted about how small they can make microchip components.Transistors have shrunk by about 1000-fold over the last 50 years,for example[1].But Cerebras Systems,Inc.of Sunnyvale,CA,USA t...For decades,manufacturers have boasted about how small they can make microchip components.Transistors have shrunk by about 1000-fold over the last 50 years,for example[1].But Cerebras Systems,Inc.of Sunnyvale,CA,USA takes pride in how big its chips are.Produced from a single silicon wafer,its Wafer-Scale Engine(WSE)-2 chips measure 46225 mm^(2),56 times the size of a standard Nvidia microprocessor(Fig.1)[2].展开更多
A set of integrated end-column amperometric detection system has been developed,onto which an electrophoresis microchip can be conveniently integrated.Finely machined by a piece of transparent organic glass,the system...A set of integrated end-column amperometric detection system has been developed,onto which an electrophoresis microchip can be conveniently integrated.Finely machined by a piece of transparent organic glass,the system consists of an electrophoresis microchip platform and an amperometric detection reservoir,in which the microchip can be fixed onto the platform by microchip grooves and with stainless steel fixture.Each detection electrode can be directly fixed in the amperometric detection reservoir by screws and nuts.With dopamine as the model analyte,we take platinum disc electrodes with different diameters of 100 μm,300 μm and 500 μm and a carbon fiber electrode with the diameter of 240 μm as the working electrode,all of which accomplish sensitive detection.The detection parameters of the system are optimized with the carbon fiber electrode.The detection results show that in the electrochemical cleaning procedure,the relative deviations of 3.2% and 0.5% for the peak current and retention time,respectively,can be obtained for the successive detections of 100 μM dopamine,and the limit of detection for dopamine can reach 0.4 μM(S/N = 3).This system is small,but its performance of detection is stable and sensitive,and the replacement of its working electrodes is convenient,so it is very suitable as a universal platform of end-column amperometric detection for electrophoresis microchips.展开更多
随着安全威胁的不断演变和日趋复杂,工业和消费应用设计人员在开发过程中必须考虑在设备中实现安全功能。为了让设计人员能轻松地将安全功能集成到应用中,Microchip Technology Inc.(美国微芯科技公司)宣布推出全新PIC32CZ CA 32位单片...随着安全威胁的不断演变和日趋复杂,工业和消费应用设计人员在开发过程中必须考虑在设备中实现安全功能。为了让设计人员能轻松地将安全功能集成到应用中,Microchip Technology Inc.(美国微芯科技公司)宣布推出全新PIC32CZ CA 32位单片机系列。该系列器件配备了300 MHz Arm Cortex M7处理器、集成硬件安全模块(HSM),支持多种连接和闪存选项,从而提高了灵活性。展开更多
文摘For decades,manufacturers have boasted about how small they can make microchip components.Transistors have shrunk by about 1000-fold over the last 50 years,for example[1].But Cerebras Systems,Inc.of Sunnyvale,CA,USA takes pride in how big its chips are.Produced from a single silicon wafer,its Wafer-Scale Engine(WSE)-2 chips measure 46225 mm^(2),56 times the size of a standard Nvidia microprocessor(Fig.1)[2].
基金supporting from the National Natural Science Foundation of China (Grant Nos.20605018 & 20975106)Beijing Natural Science Foundation (Grant No.2072018)
文摘A set of integrated end-column amperometric detection system has been developed,onto which an electrophoresis microchip can be conveniently integrated.Finely machined by a piece of transparent organic glass,the system consists of an electrophoresis microchip platform and an amperometric detection reservoir,in which the microchip can be fixed onto the platform by microchip grooves and with stainless steel fixture.Each detection electrode can be directly fixed in the amperometric detection reservoir by screws and nuts.With dopamine as the model analyte,we take platinum disc electrodes with different diameters of 100 μm,300 μm and 500 μm and a carbon fiber electrode with the diameter of 240 μm as the working electrode,all of which accomplish sensitive detection.The detection parameters of the system are optimized with the carbon fiber electrode.The detection results show that in the electrochemical cleaning procedure,the relative deviations of 3.2% and 0.5% for the peak current and retention time,respectively,can be obtained for the successive detections of 100 μM dopamine,and the limit of detection for dopamine can reach 0.4 μM(S/N = 3).This system is small,but its performance of detection is stable and sensitive,and the replacement of its working electrodes is convenient,so it is very suitable as a universal platform of end-column amperometric detection for electrophoresis microchips.
文摘随着安全威胁的不断演变和日趋复杂,工业和消费应用设计人员在开发过程中必须考虑在设备中实现安全功能。为了让设计人员能轻松地将安全功能集成到应用中,Microchip Technology Inc.(美国微芯科技公司)宣布推出全新PIC32CZ CA 32位单片机系列。该系列器件配备了300 MHz Arm Cortex M7处理器、集成硬件安全模块(HSM),支持多种连接和闪存选项,从而提高了灵活性。
