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Fractalkine: multiple strategies to counteract glutamate receptors activation leading to neuroprotection 被引量:2
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作者 Clotilde Lauro 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第8期1214-1215,共2页
Glutamate(Glu)is the main excitatory amino acid in the brain and plays a pivotal role in many neurophysiological functions.Nevertheless,an excess and prolonged exposure to Glu determines the overactivation of glutam... Glutamate(Glu)is the main excitatory amino acid in the brain and plays a pivotal role in many neurophysiological functions.Nevertheless,an excess and prolonged exposure to Glu determines the overactivation of glutamate receptors(Glu Rs)with consequent impairment of cellular calcium(Ca2+)homeostasis, 展开更多
关键词 glutamate excitatory impairment homeostasis neuronal Glutamate NMDAR intracellular adenosine microglia
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Neuroprotective role of galectin-1 in central nervous system pathophysiology 被引量:1
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作者 Ravikumar Aalinkeel Supriya D.Mahajan 《Neural Regeneration Research》 SCIE CAS CSCD 2016年第6期896-897,共2页
Galectins are a family of endogenousβglycan-binding proteins that play an important role in the modulation of inflammationassociated with neurodegeneration as seen in various neurological disorders such as dementia,m... Galectins are a family of endogenousβglycan-binding proteins that play an important role in the modulation of inflammationassociated with neurodegeneration as seen in various neurological disorders such as dementia,multiple sclerosis(MS),Alzheimer’s disease(AD)(Chen et al.,2014). 展开更多
关键词 galectin glycan neurological microglia endogenous infiltrating specifically neuronal pathology homeostasis
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