Glutamate(Glu)is the main excitatory amino acid in the brain and plays a pivotal role in many neurophysiological functions.Nevertheless,an excess and prolonged exposure to Glu determines the overactivation of glutam...Glutamate(Glu)is the main excitatory amino acid in the brain and plays a pivotal role in many neurophysiological functions.Nevertheless,an excess and prolonged exposure to Glu determines the overactivation of glutamate receptors(Glu Rs)with consequent impairment of cellular calcium(Ca2+)homeostasis,展开更多
Galectins are a family of endogenousβglycan-binding proteins that play an important role in the modulation of inflammationassociated with neurodegeneration as seen in various neurological disorders such as dementia,m...Galectins are a family of endogenousβglycan-binding proteins that play an important role in the modulation of inflammationassociated with neurodegeneration as seen in various neurological disorders such as dementia,multiple sclerosis(MS),Alzheimer’s disease(AD)(Chen et al.,2014).展开更多
文摘Glutamate(Glu)is the main excitatory amino acid in the brain and plays a pivotal role in many neurophysiological functions.Nevertheless,an excess and prolonged exposure to Glu determines the overactivation of glutamate receptors(Glu Rs)with consequent impairment of cellular calcium(Ca2+)homeostasis,
文摘Galectins are a family of endogenousβglycan-binding proteins that play an important role in the modulation of inflammationassociated with neurodegeneration as seen in various neurological disorders such as dementia,multiple sclerosis(MS),Alzheimer’s disease(AD)(Chen et al.,2014).