After injury, damaged axons have the capacity to regenerate, but the regenerative capacity of the axon, particularly axons of the central nervous system, is quite limited. This is because the damaged axons tend to ret...After injury, damaged axons have the capacity to regenerate, but the regenerative capacity of the axon, particularly axons of the central nervous system, is quite limited. This is because the damaged axons tend to retract, because they encounter obstacles such as scar tissue and inhibitory molecules, and because their growth rates simply do not match those of a juvenile axon. In recent years, there has been a focus on microtubules as among the most important factors in encouraging injured adult axons to regenerate. Microtubules are hollow polymeric filaments composed of tubulin subunits that provide structural support for the axon.展开更多
文摘After injury, damaged axons have the capacity to regenerate, but the regenerative capacity of the axon, particularly axons of the central nervous system, is quite limited. This is because the damaged axons tend to retract, because they encounter obstacles such as scar tissue and inhibitory molecules, and because their growth rates simply do not match those of a juvenile axon. In recent years, there has been a focus on microtubules as among the most important factors in encouraging injured adult axons to regenerate. Microtubules are hollow polymeric filaments composed of tubulin subunits that provide structural support for the axon.
