[Objective] The inductively coupled plasma mass spectrometry(ICP-MS)was constructed to determine the contents of lead,cadmium,mercury and arsenic in Archyranthes bidentata Blume.[Method]Under the optimum operation con...[Objective] The inductively coupled plasma mass spectrometry(ICP-MS)was constructed to determine the contents of lead,cadmium,mercury and arsenic in Archyranthes bidentata Blume.[Method]Under the optimum operation condition of ICP-MS,the samples were digested by microwave.The element 114In was taken as an internal standard element to compensate body effect and ICP-MS method was used to determine the contents of lead,cadmium,mercury and arsenic.[Result]For the determined elements,the correlation coefficient(r)of standard curve was over 0.9995 and recovery rate was from 96.7% to 106.4% while RSD was less than 11.2%.The result of determination showed that the heavy metal content in Archyranthes bidentata Blume.beyond standard was serious.[Conclusion]The constructed ICP-MS method with simple operation,rapid response,accuracy and high sensitivity in this experiment could be used for quality control of Chinese medicinal materials by detecting heavy metal contents in different Chinese medicinal materials from original places.展开更多
The research aims to set up the determination method of heavy metals in tobacco by ICP-MS and analyze its uncertainty. Microwave digest technique is used for decomposition of the tobacco samples. Bi,Sc,Ge and In are e...The research aims to set up the determination method of heavy metals in tobacco by ICP-MS and analyze its uncertainty. Microwave digest technique is used for decomposition of the tobacco samples. Bi,Sc,Ge and In are employed as internal standards to eliminate the interference of the matrix. A method is developed for simultaneous determination of Cr,Cu,As,Cd,Hg and Pb in tobacco from Yunnan Province by ICP-MS,and the measurement uncertainty is evaluated by metrological method. The test results indicate that in the content range of0- 1. 0 g / ml,the linearly dependent coefficient of six elements is 1. 0000,and the RSD achieves 1. 5%- 11%( n = 8). The elemental content in tobacco is as follows: Cr( 2. 92,0. 24) mg / kg,Cu( 3. 64,0. 24) mg / kg,As( 0. 467,0. 025) mg / kg,Cd( 3. 12,0. 15) mg / kg,Hg( 0. 035,0. 006) mg/kg,Pb( 4. 62,0. 36) mg/kg. The uncertainty of sample size,the constant volume of the sample solution can be neglected. It is concluded that the method is accurate,simple,sensitive and rapid.展开更多
目的：测定常用饮片中重金属含量。方法：用10 mL HNO_3-2 mL H_2O_2-0.5 mL HF混合酸微波消解,电感耦合等离子体原子发射光谱法测定常用中药饮片中砷、铅、铬、镉、铜、镍6种重金属元素含量。结果：不同药材中重金属含量有较大差异,不...目的：测定常用饮片中重金属含量。方法：用10 mL HNO_3-2 mL H_2O_2-0.5 mL HF混合酸微波消解,电感耦合等离子体原子发射光谱法测定常用中药饮片中砷、铅、铬、镉、铜、镍6种重金属元素含量。结果：不同药材中重金属含量有较大差异,不同产地的同一种中药材中重金属含量有明显差别,中药饮片沸水浸泡1 h后药材中重金属有不同程度的溶出。方法加标回收率为92.23%～105.31%,RSD为0.99%～6.61%（n=6）。结论：该方法具有良好的精密度和准确度,可作为中药饮片重金属含量检测的方法。展开更多
基金Supported by the National Science Foundation for Post-doctoral Scientists of China(20070410616)Excellent Youth Foundation of He'nan Scientific Committee(074100510018)~~
文摘[Objective] The inductively coupled plasma mass spectrometry(ICP-MS)was constructed to determine the contents of lead,cadmium,mercury and arsenic in Archyranthes bidentata Blume.[Method]Under the optimum operation condition of ICP-MS,the samples were digested by microwave.The element 114In was taken as an internal standard element to compensate body effect and ICP-MS method was used to determine the contents of lead,cadmium,mercury and arsenic.[Result]For the determined elements,the correlation coefficient(r)of standard curve was over 0.9995 and recovery rate was from 96.7% to 106.4% while RSD was less than 11.2%.The result of determination showed that the heavy metal content in Archyranthes bidentata Blume.beyond standard was serious.[Conclusion]The constructed ICP-MS method with simple operation,rapid response,accuracy and high sensitivity in this experiment could be used for quality control of Chinese medicinal materials by detecting heavy metal contents in different Chinese medicinal materials from original places.
基金Supported by Fund Project of Yunnan Provincial Department of Education(2013Y475)Science and Technology Project of State General Administration for Quality Supervision(2013QK071)
文摘The research aims to set up the determination method of heavy metals in tobacco by ICP-MS and analyze its uncertainty. Microwave digest technique is used for decomposition of the tobacco samples. Bi,Sc,Ge and In are employed as internal standards to eliminate the interference of the matrix. A method is developed for simultaneous determination of Cr,Cu,As,Cd,Hg and Pb in tobacco from Yunnan Province by ICP-MS,and the measurement uncertainty is evaluated by metrological method. The test results indicate that in the content range of0- 1. 0 g / ml,the linearly dependent coefficient of six elements is 1. 0000,and the RSD achieves 1. 5%- 11%( n = 8). The elemental content in tobacco is as follows: Cr( 2. 92,0. 24) mg / kg,Cu( 3. 64,0. 24) mg / kg,As( 0. 467,0. 025) mg / kg,Cd( 3. 12,0. 15) mg / kg,Hg( 0. 035,0. 006) mg/kg,Pb( 4. 62,0. 36) mg/kg. The uncertainty of sample size,the constant volume of the sample solution can be neglected. It is concluded that the method is accurate,simple,sensitive and rapid.
文摘目的：测定常用饮片中重金属含量。方法：用10 mL HNO_3-2 mL H_2O_2-0.5 mL HF混合酸微波消解,电感耦合等离子体原子发射光谱法测定常用中药饮片中砷、铅、铬、镉、铜、镍6种重金属元素含量。结果：不同药材中重金属含量有较大差异,不同产地的同一种中药材中重金属含量有明显差别,中药饮片沸水浸泡1 h后药材中重金属有不同程度的溶出。方法加标回收率为92.23%～105.31%,RSD为0.99%～6.61%（n=6）。结论：该方法具有良好的精密度和准确度,可作为中药饮片重金属含量检测的方法。
