期刊文献+
共找到25篇文章
< 1 2 >
每页显示 20 50 100
Characteristics and demographic factors of traditional Chinese medicine constitution types among elderly individuals in China:A national multistage cluster random study Author links open overlay panel
1
作者 Jing Xia Minghua Bai +6 位作者 Huirong Song Houqin Li Dayan Zhang Mary Y.Jiang Ran Chen Feiyu He Cheng Ni 《Journal of Traditional Chinese Medical Sciences》 CAS 2024年第3期257-263,共7页
Objective:To reveal the distribution characteristics and demographic factors of traditional Chinese medicine(TCM)constitution among elderly individuals in China.Methods: Elderly individuals from seven regions in China... Objective:To reveal the distribution characteristics and demographic factors of traditional Chinese medicine(TCM)constitution among elderly individuals in China.Methods: Elderly individuals from seven regions in China were selected as samples in this study using a multistage cluster random sampling method.The basic information questionnaire and Constitution in Chinese Medicine Questionnaire(Elderly Edition)were used.Descriptive statistical analysis,chi-squared tests,and binary logistic regression analysis were used.Results: The single balanced constitution(BC)accounted for 23.9%.The results of the major TCM constitution types showed that BC(43.2%)accounted for the largest proportion and unbalanced constitutions ranged from 0.9%to 15.7%.East China region(odds ratio[OR]=2.097;95%confidence interval[CI],1.912 to 2.301),married status(OR=1.341;95%CI,1.235 to 1.457),and managers(OR=1.254;95%CI,1.044 to 1.505)were significantly associated with BC.Age>70 years was associated with qi-deficiency constitution and blood stasis constitution(BSC).Female sex was significantly associated with yang-deficiency constitution(OR=1.646;95%CI,1.52 to 1.782).Southwest region was significantly associated with phlegm-dampness constitution(OR=1.809;95%CI,1.569 to 2.086).North China region was significantly associated with inherited special constitution(OR=2.521;95%CI,1.569 to 4.05).South China region(OR=2.741;95%CI,1.997 to 1.3.763),Central China region(OR=8.889;95%CI,6.676 to 11.835),senior middle school education(OR=2.442;95%CI,1.932 to 3.088),and managers(OR=1.804;95%CI,1.21 to 2.69)were significantly associated with BSC.Conclusions: This study defined the distribution characteristics and demographic factors of TCM constitution in the elderly population.Adjusting and improving unbalanced constitutions,which are correlated with diseases,can help promote healthy aging through the scientific management of these demographic factors. 展开更多
关键词 Constitution in Chinese Medicine Questionnaire(elderly Edition) Body constitution Multistage cluster random sampling Demographic factors elderly individuals
下载PDF
Coping review of dementia fear studies among middle-aged and elderly people in the community
2
作者 Hui Ren Gui-Meng Wang +3 位作者 Wen-Jing Yu Meng-Yuan Teng Jing-Mei Li Xiang-Shu Cui 《Nursing Communications》 2024年第22期1-9,共9页
This study used Arksey and O’Malley’s scoping review methodology as a framework and searched the following databases:PubMed,Embase,EBSCO,CINAHL,Web of Science,Cochrane Library,Scopus,CNKI,Wanfang,VIP,and the Chinese... This study used Arksey and O’Malley’s scoping review methodology as a framework and searched the following databases:PubMed,Embase,EBSCO,CINAHL,Web of Science,Cochrane Library,Scopus,CNKI,Wanfang,VIP,and the Chinese Biomedical Literature Database.The database is open to December 20,2023,and documents related to the fear of dementia among the elderly in the community are described and analyzed to provide a reference for future research in this field.At the same time,we screened,extracted,and summarized relevant information from 21 included documents(16 in English and 5 in Chinese),which consisted of 16 cross-sectional studies,2 quasi-experimental studies,2 randomized controlled studies,and 1 longitudinal study.Sixteen of the included documents mentioned the incidence or level of dementia fear among the elderly in the community,2 addressed the adverse effects of dementia fear,and 4 reported prevention and intervention measures for dementia fear.In total,there are 8 assessment tools,and the influencing factors are categorized into sociodemographic characteristics,psychological and behavioral characteristics,sociocultural background factors,and health and dementia-related factors.The final conclusion is that the fear of dementia is common among the elderly in the community.In the future,the application of research tools should be expanded among middle-aged individuals,with considerations for other types of dementia in mind.It is recommended to conduct large-scale,multi-center randomized controlled trials while confirming the intervention’s effect on different types of middle-aged and elderly individuals,focusing on the long-term impact of these intervention measures to promote healthy aging. 展开更多
关键词 dementia fear middle-aged and elderly people COMMUNITY scope review
下载PDF
Analysis of metabolic characteristics of metabolic syndrome in elderly patients with gastric cancer by non-targeted metabolomics
3
作者 Huan Zhang Wen-Bing Shen Lin Chen 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第6期2419-2428,共10页
BACKGROUND The relationship between metabolic syndrome(MetS)and gastric cancer(GC),which is a common metabolic disease,has attracted much attention.However,the specific metabolic characteristics of MetS in elderly pat... BACKGROUND The relationship between metabolic syndrome(MetS)and gastric cancer(GC),which is a common metabolic disease,has attracted much attention.However,the specific metabolic characteristics of MetS in elderly patients with GC remain unclear.AIM To investigate the differentially abundant metabolites and metabolic pathways between preoperative frailty and MetS in elderly patients with GC based on nontargeted metabolomics techniques.METHODS In this study,125 patients with nonfrail nonmeal GC were selected as the control group,and 50 patients with GC in the frail group were selected as the frail group.Sixty-five patients with GC combined with MetS alone were included in the MetS group,and 50 patients with GC combined with MetS were included in the MetS group.Nontargeted metabolomics techniques were used to measure plasma metabolite levels by ultrahigh-performance liquid chromatography-mass spectrometry.Multivariate statistical analysis was performed by principal component analysis,orthogonal partial least squares,pattern recognition analysis,cluster analysis,and metabolic pathway annotation.RESULTS A total of 125 different metabolites,including amino acids,glycerophospholipids,sphingolipids,fatty acids,sugars,nucleosides and nucleotides,and acidic compounds,were identified via nontargeted metabolomics techniques.Compared with those in the control group,there were 41,32,and 52 different metabolites in the MetS group,the debilitated group,and the combined group,respectively.Lipid metabolites were significantly increased in the MetS group.In the weak group,amino acids and most glycerol phospholipid metabolites decreased significantly,and fatty acids and sphingosine increased significantly.The combined group was characterized by significantly increased levels of nucleotide metabolites and acidic compounds.The alanine,aspartic acid,and glutamate metabolic pathways were obviously enriched in the asthenic group,and the glycerol and phospholipid metabolic pathways were obviously enriched in the combined group.CONCLUSION Elderly GC patients with simple frailty,simple combined MetS,and frailty combined with MetS have different metabolic characteristics,among which amino acid and glycerophospholipid metabolite levels are significantly lower in frail elderly GC patients,and comprehensive supplementation of fat and protein should be considered.Many kinds of metabolites,such as amino acids,lipids,nucleotides,and acidic compounds,are abnormally abundant in patients with MetS combined with fthenia,which may be related to tumor-related metabolic disorders. 展开更多
关键词 Nervous breakdown Metabolic syndrome elderly individuals Gastric cancer Nontargeted metabolomics
下载PDF
Metabolic Disorders Increase the Risk to Incident Cardiovascular Disease in Middle-aged and Elderly Chinese 被引量:7
4
作者 ZHANG Ming Liang HOU Xu Hong +4 位作者 ZHU Yun Xia LU Jun Xi PENG Liang Pu GU Hui Lin JIA Wei Ping 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2012年第1期38-45,共8页
Objective The association of metabolic syndrome (MetS) with cardiovascular diseases (CVD) has not been adequately explored in middle-aged and elderly Chinese. This study aimed to investigate MetS' prevalence and ... Objective The association of metabolic syndrome (MetS) with cardiovascular diseases (CVD) has not been adequately explored in middle-aged and elderly Chinese. This study aimed to investigate MetS' prevalence and its impact on the CVD incidence in this specific population group. Methods A data set of a community-based prospective cohort study was analyzed. A total of 2300 subjects aged 40-94 years were followed up for the CVD events. MetS defined according to the JCDCG criteria was assessed at baseline, and the middle-aged and elderly groups were classified by the WHO definition. Results As compared with the middle-aged group, the prevalence of MetS increased by 0.6 times (34.6% vs. 21.3%) and the incidence density of CVD increased by 4.9 times in the elderly group (52.3/1000 person-year vs. 8.9/1000 person-year). Furthermore, the multivariate Cox regression revealed that the risk to CVD incidence was independently related to increased waist circumference in the middle-aged group (HR=2.23, P〈0.01) and to elevated blood glucose in the elderly group (HR=1.39, P〈O.01). Conclusion MetS was highly prevalent in middle-aged and elderly Chinese. MetS significantly increased the risk to OdD incidence in the elderly. All individuals with metabolic disorders should receive active clinical care to reduce the incidence of CVD. 展开更多
关键词 Metabolic syndrome Cardiovascular disease The middle-aged The elderly
下载PDF
Public Square Dancing Intervention on Subjective Well-Being of Middle-Aged and Elderly People:A Meta-Analysis
5
作者 Menglong Li Xia Jiang Yujia Ren 《International Journal of Mental Health Promotion》 2022年第1期129-142,共14页
Objective:To understand the influence of public square dancing on the subjective well-being of middle-aged and elderly people.Methods:According to the principle of Preferred Reporting Items for Systematic Reviews and ... Objective:To understand the influence of public square dancing on the subjective well-being of middle-aged and elderly people.Methods:According to the principle of Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA)guidelines,we search Chinese databases,such as CNKI,Wanfang Data,and VIP,and English databases,such as Proquest,Web of Science,Pubmed,Cochrane,and ScienceDirect,and collect relevant articles at home and abroad from 2006 to December 2019 for meta-analysis in January 2020.Result:A total of 10 articles were included.The meta-analysis results showed that the well-being of middle-aged and elderly people in the public square dancing intervention group was significantly higher than that of the other exercise group and control group(both P<0.01).The results of the subgroup analysis showed the following:Different durations of intervention significantly influence the intervention effect(P<0.01).No difference was found between the effect of the mixed-gender intervention and the individual female intervention(P>0.05).No significant difference was found between the groups with weekly intervention frequency(P>0.05).Conclusion:Public square dancing intervention is effective for middle-aged and elderly people’s subjective well-being.Neither mixed intervention nor the times of weekly intervention have an impact on the intervention effect.However,the length of duration of intervention influences the intervention effect. 展开更多
关键词 middle-aged and elderly people subjective well-being META-ANALYSIS square dancing
下载PDF
Relationship between platelet-lymphocyte ratio and carotid atherosclerosis in middle-aged and elderly patients with type 2 diabetes mellitus
6
作者 Jing Hu Kun Zhao +6 位作者 Shao-Ling Yang Feng-Ling Wang Qiao-Na Zhang Lin-Yan Fan Hong-Zhen Zhang Wen-Hua Lin Jia-Hong Gu 《Journal of Hainan Medical University》 2022年第2期34-39,共6页
Objective:To investigate the relationship between platelet-lymphocyte ratio(PLR)and carotid atherosclerosis(CAS)in middle-aged and elderly patients with T2DM.Methods:A total of 420 middle-aged and elderly patients wit... Objective:To investigate the relationship between platelet-lymphocyte ratio(PLR)and carotid atherosclerosis(CAS)in middle-aged and elderly patients with T2DM.Methods:A total of 420 middle-aged and elderly patients with T2DM who were hospitalized in the Endocrinology Department of our hospital from September 2018 to September 2020 and were examined by ultrasound were selected as the subjects.The carotid artery intima-media thickness(CIMT)was examined by color Doppler ultrasonography,including normal CIMT group(n=111),CIMT thickening group(n=103)and CAS plaque group(n=206).The differences of serum PLR levels among the three groups were compared.Multivariate Logistic regression was used to analyze the relationship between PLR and CAS plaque formation.The receiver operating curve(ROC)was used to evaluate the value of multivariate Logistic regression model(Logit P)in the diagnosis of CAS lesions.Results:The mean value of PLR in CAS plaque group(127.86±48.54)was significantly higher than that in CIMT normal group(109.15±48.35).Multivariate Logistic regression analysis showed that after adjusting for other confounding factors,the increase of PLR was an independent risk factor for the occurrence of CAS plaque.ROC showed that the efficacy of multivariate Logit P model in the diagnosis of CAS plaque was(AUC=0.807,95%CI=0.759-0.858).Conclusions:PLR is one of the important risk factors for the occurrence of CAS lesions.At the same time,the multivariate Logistic regression model established in this study has clinical reference value in predicting CAS lesions in middle-aged and elderly patients with T2DM. 展开更多
关键词 Type 2 diabetes mellitus middle-aged and elderly PLR Carotid artery intima-media thickness Atherosclerotic plaque
下载PDF
Associations of short-term ambient temperature exposure with lung function in middle-aged and elderly people:A longitudinal study in China
7
作者 Weihong Qiu Bin Wang +9 位作者 Xiaobing Feng Heng He Lieyang Fan Zi Yea Xiuquan Nie Ge Mua Wei Liu Dongming Wang Min Zhou Weihong Chen 《Eco-Environment & Health》 2024年第2期165-173,共9页
The short-term associations of ambient temperature exposure with lung function in middle-aged and elderly Chinese remain obscure.The study included 19,128 participants from the Dongfeng-Tongji cohort's first(2013)... The short-term associations of ambient temperature exposure with lung function in middle-aged and elderly Chinese remain obscure.The study included 19,128 participants from the Dongfeng-Tongji cohort's first(2013)and second(2018)follow-ups.The lung function for each subject was determined between April and December 2013 and re-assessed in 2018,with three parameters(forced vital capacity[FVC],forced expiratory volume in 1 s[FEV1],and peak expiratory flow[PEF])selected.The China Meteorological Data Sharing Service Center provided temperature data during the study period.In the two follow-ups,a total of 25,511 records(average age:first,64.57;second,65.80)were evaluated,including 10,604 males(41.57%).The inversely J-shaped associations between moving average temperatures(lag01–lag07)and FVC,FEV1,and PEF were observed,and the optimum temperatures at lag04 were 16.5C,18.7C,and 16.2C,respectively.At lag04,every 1C increase in temperature was associated with 14.07 mL,9.78 mL,and 62.72 mL/s increase in FVC,FEV1,and PEF in the lowtemperature zone(<the optimum temperatures),whereas 5.72 mL,2.01 mL,and 11.64 mL/s decrease in the high-temperature zone(the optimum temperatures),respectively(all P<0.05).We observed significant effect modifications of gender,age,body mass index,body surface area,smoking status,drinking status,and physical activity on the associations(all Pmodification<0.05).Non-optimal temperatures may cause lung function decline.Several individual characters and lifestyles have effect modification on the temperature effects. 展开更多
关键词 Ambient temperature Lung function middle-aged and elderly people Vulnerable groups Linear mixed-effects model Generalized additive mixed model
原文传递
“Care That Respects Individuality” Provided to Elderly People with Dementia as Perceived by Japanese Dementia Carers Qualified
8
作者 Takako Nakagawa Akemi Fujita Yoshiko Nishizawa 《Open Journal of Nursing》 2017年第11期1227-1245,共19页
The objective of this study was to clarify the contents of “care that respects individuality” provided to elderly people with dementia living in group homes as perceived by dementia carers qualified. We interviewed ... The objective of this study was to clarify the contents of “care that respects individuality” provided to elderly people with dementia living in group homes as perceived by dementia carers qualified. We interviewed 21 dementia carers qualified working at group homes in Prefecture A about the practical contents of and their thoughts on “care that respects individuality”. The data obtained from the interviews were analyzed using the modified grounded theory approach (M-GTA). As a result, 14 concepts regarding the contents of “care that respects individuality” provided to elderly people with dementia living in group homes as perceived by dementia carers qualified were generated in the following 4 categories: “placing emphasis on the individual”, “respecting feelings”, “eliciting strengths”, and “close mutual relationship”. 展开更多
关键词 elderly Person with DEMENTIA Group Home CARE individuALITY DEMENTIA CARERS QUALIFIED
下载PDF
Effects of social capital on the health quality of the rural elderly in Xihaigu,China: a hierarchical linear model analysis 被引量:1
9
作者 Yang Lu 《Chinese Journal of Population,Resources and Environment》 2019年第2期184-195,共12页
Based on the analysis and measurement of the social capital and the health quality and structure of the elderly people,this paper examined the effects of social capital on the health quality of the elderly as well as ... Based on the analysis and measurement of the social capital and the health quality and structure of the elderly people,this paper examined the effects of social capital on the health quality of the elderly as well as its composition.The examination was conducted by applying a hierarchical linear model (HLM) and using survey data obtained in the Xihaigu area of Ningxia Province in 2017.The empirical results showed that individual social capital had a significant influence on the health of the rural elderly,but the impacts were different on its composition.Village social capital should improve both the physical and mental health quality of the elderly through building mutual trust and promoting stability,unity and a harmonious living environment.In addition,factors such as mode of habitation,diet,medical approaches,intergenerational interactions,and village geographical location also affect the health quality of the elderly. 展开更多
关键词 The elderly HEALTH QUALITY individual SOCIAL CAPITAL VILLAGE SOCIAL CAPITAL
下载PDF
High Sensitivity C-Reactive Protein Associated with Different Health Predictors in Middle-Aged and oldest old Chinese
10
作者 ZHAI Yi SHI Xiao Ming +7 位作者 FITZGERALD Simon Michael QIAN Han Zhu KRAUS Virginia B SERENY Melanie HU Perry YIN Zhao Xue XU Jian Wei ZENG Yi 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2012年第3期257-266,共10页
Objective To describe the distribution of plasma high sensitivity C-reactive protein (hsCRP) and explore the relationship between hsCRP and metabolic risk factors among residents living in longevity areas of China. ... Objective To describe the distribution of plasma high sensitivity C-reactive protein (hsCRP) and explore the relationship between hsCRP and metabolic risk factors among residents living in longevity areas of China. Methods 268 individuals aged between 40 and 59 years and 506 individuals aged over 90 years were selected from 5 longevity areas of China to participate in a cross section longitudinal cohort study. The participants were interviewed with general health related questionnaire to collect their demographic, behavioral and lifestyle data, as well as their chronic conditions, and meanwhile their physical and biomedical parameters including waist circumference (WC), blood pressure (BP), hsCRP, plasma lipids, and fasting blood glucose (FBG) were measured. Results The median of hsCRP was 0.99 mg/L in the middle-aged group and 2.76 mg/L in the oldest old group. No significant gender difference was observed between the above two groups. Among the oldest old individuals, 36.56% had an hsCRP level 〉3.0 mg/L. The prevalence of high hsCRP was 26.79% in the middle-aged group. The results of stepwise multiple linear regression analyses showed that HDL-C was independently associated with In (hsCRP) concentration in the middle-aged group, whereas In (TG), HDL-C and FBG were correlated after adjustment for gender, study site, smoking, drinking, education and BMI in the oldest old group. Conclusion HDL-C is a stronger predictor of elevated hsCRP than other metabolic factors in the middle-aged population. For the oldest old persons, high TG, low HDL-C, and FBG predict elevated plasma hsCRP. 展开更多
关键词 High-sensitivity C-reactive protein Blood lipids Fasting blood glucose middle-aged Oldestold individuals LONGEVITY China
下载PDF
Nomogram prediction model called“ADPLCP”for predictinglinezolid-associated thrombocytopenia in elderly individuals
11
作者 Yanxin Liu Jiang Wang +4 位作者 Tingting Liu Kun Xiao Peng Yan Xiangqun Fang Lixin Xie 《Journal of Intensive Medicine》 CSCD 2023年第3期268-274,共7页
Background:Linezolid-associated thrombocytopenia(LAT)leads to drug withdrawal associated with a poor prognosis.Some risk factors for LAT have been identified;however,the sample size of previous studies was small,data ... Background:Linezolid-associated thrombocytopenia(LAT)leads to drug withdrawal associated with a poor prognosis.Some risk factors for LAT have been identified;however,the sample size of previous studies was small,data from elderly individuals are limited,and a simple risk score scale was not established to predict LAT at anearly stage,making it difficult to identify and intervene in LAT at an early stage.Methods:In this single-center retrospective case-control study,we enrolled elderly patients treated with linezolidin the intensive care unit from January 2015 to December 2020.All the data of enrolled patients,includingdemographic information and laboratory findings at baseline,were collected.We analyzed the incidence andrisk factors for LAT and established a nomogram risk prediction model for LAT in the elderly population.Results:A total of 428 elderly patients were enrolled,and the incidence of LAT was 35.5%(152/428).Age≥80 years old(OR=1.980;95%CI:1.179–3.325;P=0.010),duration of linezolid≥10 days(OR=1.100;95%CI:1.050–1.152;P<0.0001),platelet count at baseline(100–149×10^(9)/L vs.≥200×10^(9)/L,OR=8.205,95%CI:4.419–15.232,P<0.0001;150–199×10^(9)/L vs.≥200×10^(9)/L,OR=3.067,95%CI:1.676–5.612,P<0.001),leukocytecount at baseline≥16×10^(9)/L(OR=2.580;95%CI:1.523–4.373;P<0.0001),creatinine clearance<50 mL/min(OR=2.323;95%CI:1.388–3.890;P=0.001),and total protein<60 g/L(OR=1.741;95%CI:1.039–2.919;P=0.035)were associated with LAT.The nomogram prediction model called“ADPLCP”(age,duration,platelet,leukocyte,creatinine clearance,protein)was established based on logistic regression.The area under the curve(AUC)of ADPLCP was 0.802(95%CI:0.748–0.856;P<0.0001),with 78.9%sensitivity and 69.2%specificity(cut-off was 108).Risk stratification for LAT was performed based on“ADPLCP.”Total points of<100 were defined as low risk,and the possibility of LAT was<32.0%.Total points of 100–150 were defined as medium risk,and the possibility of LAT was 32.0–67.5%.A total point>150 was defined as high risk,and the probability ofLAT was>67.5%.Conclusions:We created the ADPLCP risk score scale to predict the occurrence of LAT in elderly individuals.ADPLCP is simple and feasible and is helpful for the early determination of LAT to guide drug withdrawal orearly intervention. 展开更多
关键词 Linezolid-associated thrombocytopenia NOMOGRAM Risk prediction model elderly individuals
原文传递
不同心理类型中老年婚恋特点的个案研究
12
作者 包华 《语言与文化研究》 2024年第6期260-262,共3页
使用荣格心理类型和自性化理论,对极端思维型、典型感觉型中老年婚恋心理和行为进行个案分析,对四种心理类型个体的婚恋行为和情感特征进行童年情结的根源探索,指出实现中老年婚恋和心理健康的道路是发展其他心理机能尤其是对立面心理... 使用荣格心理类型和自性化理论,对极端思维型、典型感觉型中老年婚恋心理和行为进行个案分析,对四种心理类型个体的婚恋行为和情感特征进行童年情结的根源探索,指出实现中老年婚恋和心理健康的道路是发展其他心理机能尤其是对立面心理机能的情绪和行为,通过走出个人情结、避免偏激、发展复合型人格,最终实现自性化圆满和身心健康。 展开更多
关键词 心理类型 自性化 情结 中老年 婚恋 个案研究
下载PDF
Identification of late-onset hypogonadism in middle-aged and elderly men from a community of China 被引量:8
13
作者 Zhi-Yong Liu Ren-Yuan Zhou +4 位作者 Xin Lu Qin-Song Zeng Hui-Qing Wang Zheng Li Ying-Hao Sun 《Asian Journal of Andrology》 SCIE CAS CSCD 2016年第5期747-753,共7页
In this study, we investigated the essential criteria for late-onset hypogonadism (LOH) syndrome based on the presence of symptoms associated with low testosterone levels in Han Chinese men. Blood tests for total te... In this study, we investigated the essential criteria for late-onset hypogonadism (LOH) syndrome based on the presence of symptoms associated with low testosterone levels in Han Chinese men. Blood tests for total testosterone (TT) and sex hormone-binding globulin (SHBG) were performed, and the aging male symptoms (AMS) questionnaire was conducted in a randomly selected cohort composed of 944 Chinese men aged 40 to 79 years from nine urban communities. Three sexual symptoms (decreased ability/frequency of sexual activity, decreased number of morning erections, and decreased libido) were confirmed to be related to the total and free testosterone levels. The thresholds for TT were approximately 12.55 nmol l^-1 for a decreased ability/frequency to perform sex, 12.55 nmol l^-1 for decreased frequency of morning erections, and 14.35 nmol l^-1 for decreased sexual desire. The calculated free testosterone (CFT) thresholds for these three sexual symptoms were 281.14, 264.90, and 287.21 pmol l^-1, respectively. TT 〈13.21 nmol l^-1 (OR =1.4, 95%Ch 1.0-1.9, P= 0.037) or CFT 〈268.89 pmol l^-1 (OR - 1.5, 95%Ch 1.1-20, P=0.020) was associated with an increase in the aforementioned three sexual symptoms. The prevalence of LOH was 9.1% under the criteria, including all three sexual symptoms with TT levels 〈13.21 nmol l^-1 and CFT levels 〈268.89 pmol l^-1. Our results may improve the diagnostic accuracy of LOH in older men. 展开更多
关键词 diagnosis HYPOGONADISM middle-aged and elderly male reference values sexual dysfunction TESTOSTERONE
原文传递
Prevalence of late-onset hypogonadism among middle-aged and elderly males in China:results from a national survey 被引量:9
14
作者 Yi-Jun Liu Xu-Bo Shen +6 位作者 Na Yu Xue-Jun Shang Yi-Qun Gu Lian-Dong Zuo Cheng-Liang Xiong Zhen Ye Yuan-Zhong Zhou 《Asian Journal of Andrology》 SCIE CAS CSCD 2021年第2期170-177,共8页
This study aimed to propose an operational definition of late-onset hypogonadism(LOH)that incorporates both clinical symptoms and serum testosterone measurements to evaluate the prevalence of LOH in aging males in Chi... This study aimed to propose an operational definition of late-onset hypogonadism(LOH)that incorporates both clinical symptoms and serum testosterone measurements to evaluate the prevalence of LOH in aging males in China.A population-based sample of 6296 men aged 40 years-79 years old was enrolled from six representative provinces in China.Serum total testosterone(TT),sex hormone-binding globulin(SHBG),and luteinizing hormone(LH)were measured and free testosterone(cFT)was calculated.The Aging Males’Symptoms(AMS)scale was used to evaluate the LOH symptoms.Finally,5078 men were included in this analysis.The TT levels did not decrease with age(P=0.59),and had no relationship with AMS symptoms(P=0.87 for AMS total score,P=0.74 for≥3 sexual symptoms).The cFT levels decreased significantly with age(P<0.01)and showed a negative association with the presence of≥3 sexual symptoms(P=0.03).The overall estimated prevalence of LOH was 7.8%(395/5078)if a cFT level<210 pmol l−1 combined with the presence of≥3 sexual symptoms was used as the criterion of LOH.Among them,26.1%(103/395)and 73.9%(292/395)had primary and secondary hypogonadism,respectively.After adjustment for confounding factors,primary and secondary hypogonadism was positively related to age and comorbidities.Body mass index was an independent risk factor for secondary hypogonadism.The results suggest that the AMS total score is not an appropriate indicator for decreased testosterone,and that the cFT level is more reliable than TT for LOH diagnosis.Secondary hypogonadism is the most common form of LOH. 展开更多
关键词 Aging Males'Symptoms calculated free testosterone late-onset hypogonadism middle-aged and elderly male total testosterone
原文传递
Prevalence and influence factors of self-medication in Chinese middle-aged and elderly people: evidence from 2011, 2013 and 2015 CHARLS panel data 被引量:9
15
作者 Zhuangfei Wang Xiaodong Guan +3 位作者 Yue Zhou Sheng Han Peng Yao Luwen Shi 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2019年第6期430-438,共9页
Self-medication is an increasingly frequent phenomenon worldwide and has an important influence on health.In this study,we analyzed the self-medication prevalence rate in Chinese middle-aged and elderly people,and exp... Self-medication is an increasingly frequent phenomenon worldwide and has an important influence on health.In this study,we analyzed the self-medication prevalence rate in Chinese middle-aged and elderly people,and explored the influence factors.The data from China Health and Retirement Longitudinal Study(CHARLS)in 2011,2013 and 2015 were used.Self-medication prevalence was calculated as the number of whole people divided by the number of people taking self-medication.The influence factors of self-medication were analyzed by panel data random effect model.We excluded observations with missing values in our analysis,leaving 16 962,17 876 and 19 572 observations in 2011,2013 and 2015,respectively.The average 3-year self-medication prevalence was 45.52%.Moreover,11.70%of respondents practiced self-medication with prescription medicine in 2011,2013 and 2015.Respondents living in non-rural areas(P=0.009)and western region(P=0.000)took more self-medication.Self-medication was a common phenomenon among middle-aged and elderly population in China.The government should strengthen the guidance for the middle-aged and elderly people who took more self-medication,such as those living in urban and western region. 展开更多
关键词 SELF-MEDICATION PREVALENCE Influence factors Chinese middle-aged and elderly people
原文传递
Prevalence of stroke and metabolic disorders in the middle-aged and elderly Chinese with type 2 diabetes 被引量:5
16
作者 Zhang Xuebing Mu Yiming +2 位作者 Yan Wenhua Ba Jianming Li Hongmei 《Chinese Medical Journal》 SCIE CAS CSCD 2014年第20期3537-3542,共6页
Background Stroke is now the most prevalent and debilitating disease affecting diabetic population in China. The study aimed to investigate the prevalence of stroke and metabolic disorders in the middle-aged and elder... Background Stroke is now the most prevalent and debilitating disease affecting diabetic population in China. The study aimed to investigate the prevalence of stroke and metabolic disorders in the middle-aged and elderly Chinese with type 2 diabetes. Methods A total of 4 629 subjects with type 2 diabetes (males: 1 917; females: 2 712) aged ≥ 40 years from Shijingshan district, Beijing, China from November 2011 to August 2012 were included in the study. Data on demographic information, lifestyle, history of diabetes mellitus, stroke, coronary heart disease, hypertension, and dyslipidemia were collected. The oral glucose tolerance test or a standard meal test was performed. Non-fatal stroke was reported by the subjects. The 2-tailed test was used, and P 〈0.05 was regarded as statistically significant. Results Prevalence of stroke in the subjects with type 2 diabetes was 5.5%. The prevalence of smoking, overweight or obesity, hypertension, and dyslipidemia was 41.0%, 65.8%, 67.4%, and 52.0% in males, and 2.2%, 65.5%, 69.5%, and 57.6% in females. Multivariate Logistic regression analysis showed that increased age, hypertension, diabetic duration, and overweight or obesity were positively correlated with stroke in the population with type 2 diabetes, whereas high- density lipoprotein cholesterol level was negatively correlated with stroke. After adjustment for age and gender, the odds ratio values of stroke in subjects having 1,2 or ≥3 of 4 risk factors, including smoking, overweight or obesity, hypertension and dyslipidemia, were 2.302 (95% CI: 0.789-6.712), 4.089 (95% CI: 1.470-11.373), 6.023 (95% CI: 2.176-16.666), compared with subjects without any of the above 4 risk factors. Conclusions The prevalence of stroke was higher in middle-aged and eldedy Chinese with type 2 diabetes than that in the general population. With the aggregation of risk factors, the prevalence of stroke increased. 展开更多
关键词 middle-aged and elderly STROKE type 2 diabetes metabolic disorders
原文传递
The Association between Interpersonal Relationship and Erectile Dysfunction of Middle-Aged and Elderly Men in a Rural Area of Zhejiang,China
17
作者 Qun-Feng Liang Xiao-Hua Yu +7 位作者 Shu-Cheng Zhang Jian-Hui Li Jing Zhao Jun-Biao Zheng Yi-Hua Gu Wei-Jin Zhou Guo-Qing Liang Qian-Xi Zhu 《Reproductive and Developmental Medicine》 CSCD 2018年第2期111-115,共5页
Objective:To explore the association between interpersonal relationship and erectile dysfunction(ED)of middle-aged and elderly men.Methods:A population-based cross-sectional research was conducted in the rural area of... Objective:To explore the association between interpersonal relationship and erectile dysfunction(ED)of middle-aged and elderly men.Methods:A population-based cross-sectional research was conducted in the rural area of Jiashan County,Zhejiang Province,in 2016.Middle-aged and elderly men(aged 40-80)were selected as study participants.The face-to-face questionnaire was collected,including basic information,lifestyles,interpersonal relationship,and sexual function.The interpersonal relationship was evaluated based on marital relationship,neighborhood relationship,and relatives/friends relationship.According to the International index of erectile function,the study participants were divided into ED group(mild ED,moderate-to-severe ED),and non-ED group.Correlations were evaluated between interpersonal relationship indices and the prevalence or the severity of ED.Potential confounders were adjusted by the logistical regression model.Results:There were 674 study participants with average age of 60.4±8.5 years,and 489 ED patients with prevalence of 72.6%.With age increasing,the prevalence and the severity of ED increased significantly.The men who could get help from spouse when an emergency occurred or who were more cared about by their neighbors had lower ED risk,and odds ratios(ORs)(95%confidence intervals[CIs])were 0.23(0.13-0.42)and 0.58(0.46-0.75),respectively.After the adjustment of the covariates(age,education degree,household income,smoking,and drinking),the ORs(95%CIs)were 0.29(0.14-0.60)and 0.54(0.39-0.74),respectively.Good marital relationship and good neighborhood relationship were associated with a less severity of ED. 展开更多
关键词 Erectile Dysfunction Interpersonal Relationship Marital Relationship middle-aged and elderly Men
原文传递
Study on Prevention and Treatment of Kidney Deficiency and Bone Mineral Loss in Middle-Aged and Elderly Female Diabetes Patients
18
作者 朱立群 刘英华 周荫保 《Chinese Journal of Integrative Medicine》 SCIE CAS 1996年第4期274-277,共4页
In this study, 48 cases of middle-aged and elderly female diabetes patients were dividedrandomly into two groups, and treated separately by western medicine alone ( glibenclamide) in group A, andby traditional Chinese... In this study, 48 cases of middle-aged and elderly female diabetes patients were dividedrandomly into two groups, and treated separately by western medicine alone ( glibenclamide) in group A, andby traditional Chinese medicine (herbs that replenish the Kidney and activate blood circulation ) and gliben-clamide in group B. Before treatment, the patients of both groups had elevated glycosylated hemoglobin(HbAlc) and fast blood glucose (FBG) levels, decreased serum estradiol (E2 ) and testosterone/estradiol(E2/T) ratio, and the loss of bone mineral (elevated urinary calcium,phosphorus levels) . Most ot the pa-tients in the two groups had the symptoms of soreness and weakness of the loins and knees, general weak-ness ,dizziness,decreased sexual libido , palpitation and frequent urination , etc. These symptoms in traditionalChinese medicine belong to the deficiency of the Kidney. After treatment in both groups. the patients' serumHbAlc, FBG, and urinary Beta-2-microglobulin (B2M) got reduced, the concentration of serum sex hormone(E2 , E2/T ratio) elevated, and the elimination of urinary calcium, phosphorus levels cut down. But , the ther-apeutic effect in group B is apparently better than that in group A. The symptoms of deficiency of the Kidneywas apparently improved in group B. So, The authors think the medicinal herbs(reinforcing Kidney and acti-vating blood circulation) have an important role in the prevention and treatment of the 'Kidney deficiency'and bone mineral loss in middle-aged and elderly female diabetes patients. 展开更多
关键词 middle-aged and elderly female diabetes Kidney deticiency bone mineral loss treatmentby traditional Chinese medicine and western medicine
原文传递
Effect of Atorvastatin on the levels of adiponectin and leptin and adiponectin-leptin ratio in the elderly and middle-aged patients with type 2 diabetes and combined hyperlipidemia 被引量:1
19
作者 王婧秋 《China Medical Abstracts(Internal Medicine)》 2017年第1期20-,共1页
Objective To evaluate effects of Atorvastatin on the levels of adiponectin and leptin and adiponectin-leptin ratio in the elderly and middle-aged patients with type 2diabetes and combined hyperlipidemia.Methods Totall... Objective To evaluate effects of Atorvastatin on the levels of adiponectin and leptin and adiponectin-leptin ratio in the elderly and middle-aged patients with type 2diabetes and combined hyperlipidemia.Methods Totally80 elderly and middle-aged patients with type 2 diabetes and combined hyperlipidemia were treated with Atorvastatin(10 mg/d)for 12 weeks.Fasting plasma levels 展开更多
关键词 type Effect of Atorvastatin on the levels of adiponectin and leptin and adiponectin-leptin ratio in the elderly and middle-aged patients with type 2 diabetes and combined hyperlipidemia APN HDL LDL
原文传递
The study of the correlation between serum uric acid and insulin resistance in middle-aged and elderly hospitalized patients with type 2 diabetes 被引量:1
20
作者 牟忠卿 《China Medical Abstracts(Internal Medicine)》 2017年第1期21-,共1页
Objective To study the relationship between serum uric acid and insulin resistance in type 2 diabetic patients.Methods A total of 728 middle-aged and elderly type 2 diabetic patients were recruited and the anthropomet... Objective To study the relationship between serum uric acid and insulin resistance in type 2 diabetic patients.Methods A total of 728 middle-aged and elderly type 2 diabetic patients were recruited and the anthropometric,clinical and biochemical parameters and 展开更多
关键词 acid The study of the correlation between serum uric acid and insulin resistance in middle-aged and elderly hospitalized patients with type 2 diabetes type
原文传递
上一页 1 2 下一页 到第
使用帮助 返回顶部