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A 1kHz Fe:ZnSe Laser Gain-Switched by a ZnGeP2 Optical Parametric Oscillator at 77 K 被引量:5
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作者 Ying-Yi Li Ke Yang +5 位作者 Gao-You Liu Li-Wei Xu Bao-Quan Yao You-Lun Ju Tong-Yu Bai Xiao-Ming Duan 《Chinese Physics Letters》 SCIE CAS CSCD 2019年第7期39-42,共4页
We demonstrate a Fe:ZnSe laser gain-switched by a 2.9 m ZnGeP2 optical parametric oscillator under pulse repetition frequency of 1 kHz at liquid nitrogen temperature of 77 K. The maximum output power is 63 m W with pu... We demonstrate a Fe:ZnSe laser gain-switched by a 2.9 m ZnGeP2 optical parametric oscillator under pulse repetition frequency of 1 kHz at liquid nitrogen temperature of 77 K. The maximum output power is 63 m W with pulse duration of 34.4 ns. The wavelength covers 3686.6–4088.6 nm and centers at 3897.7 nm. The output power decreases with increasing the temperature of the crystal in 77–222 K. 展开更多
关键词 demonstrate optical PARAMETRIC CRYSTAL in 77-222 K
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All-optical switching and nonlinear optical properties of HBT in ethanol solution 被引量:3
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作者 郑加金 张桂兰 +2 位作者 郭阳雪 李向平 陈文驹 《Chinese Physics B》 SCIE EI CAS CSCD 2007年第4期1047-1051,共5页
This paper demonstrates an all-optical switching model system comprising a single pulsed pump beam at 355 nm and a CW He-Ne signal beam at 632.8 nm with 2-(2'-hydroxyphenyl)benzothiazole (HBT) in ethanol solution... This paper demonstrates an all-optical switching model system comprising a single pulsed pump beam at 355 nm and a CW He-Ne signal beam at 632.8 nm with 2-(2'-hydroxyphenyl)benzothiazole (HBT) in ethanol solution. The origins of the optical switching effect were discussed. By the study of nonlinear optical properties for HBT in ethanol solvent, this paper verified that the excited-state intramolecular proton transfer (ESIPT) effect of HBT and the thermal effect of solvent worked on quite different time scales and together induced the change of the refractive index of HBT solution, leading to the signal beam deflection. The results indicated that the HBT molecule could be an excellent candidate for high-speed and high-sensitive optical switching devices. 展开更多
关键词 all-optical switching 2-(2'-hydroxyphenyl benzothiazole ESIPT nonlinear optical properties
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Low noise,continuous-wave single-frequency 1.5-μm laser generated by a singly resonant optical parametric oscillator 被引量:3
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作者 刘建丽 刘勤 +2 位作者 李宏 李鹏 张宽收 《Chinese Physics B》 SCIE EI CAS CSCD 2011年第11期312-316,共5页
We report a low noise continuous-wave (CW) single-frequency 1.5-μm laser source obtained by a singly resonant optical parametric oscillator (SRO) based on periodically poled lithium niobate (PPLN). The SRO was ... We report a low noise continuous-wave (CW) single-frequency 1.5-μm laser source obtained by a singly resonant optical parametric oscillator (SRO) based on periodically poled lithium niobate (PPLN). The SRO was pumped by a CW single-frequency Nd:YVO4 laser at 1.06μm. The 1.02 W of CW single-frequency signal laser at 1.5 μm was obtained at pump power of 6 W. At the output power of around 0.75 W, the power stability was better than ±l.5% and no mode-hopping was observed in 30 min and frequency stability was better than 8.5 MHz in 1 min. The signal wavelength could be tuned from 1.57 to 1.59 μm by varying the PPLN temperature. The 1.5-μm laser exhibits low noise characteristics, the intensity noise of the laser reaches the shot noise limit (SNL) at an analysis frequency of 4 MHz and the phase noise is less than 1 dB above the SNL at analysis frequencies above 10 MHz. 展开更多
关键词 singly resonant optical parametric oscillator 1.5-μm laser single-frequency operation low noise
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A Tilt-correction Adaptive Optical System for the Solar Telescope of Nanjing University 被引量:4
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作者 Chang-HuiRao Wen-HanJiang +8 位作者 ChengFang NingLing Wei-ChaoZhou Ming-DeDing Xue-JunZhang Dong-HongChen meiLi Xiu-FaGao TianMi 《Chinese Journal of Astronomy and Astrophysics》 CSCD 北大核心 2003年第6期576-586,共11页
A tilt-correction adaptive optical system installed on the 430 mm Solar Telescope of Nanjing University has been put in operation. It consists of a tip-tilt mirror, a correlation tracker and an imaging CCD camera. An ... A tilt-correction adaptive optical system installed on the 430 mm Solar Telescope of Nanjing University has been put in operation. It consists of a tip-tilt mirror, a correlation tracker and an imaging CCD camera. An absolute difference algorithm is used for detecting image motion in the correlation tracker. The sampling frequency of the system is 419 Hz. We give a description of the system's configuration, an analysis of its performance and a report of our observational results. A residual jitter of 0.14 arcsec has been achieved. The error rejection bandwidth of the system can be adjusted in the range 5-28 Hz according to the beacon size and the strength of atmospheric turbulence. 展开更多
关键词 telescopes - atmospheric effects - instrumentation - adaptive optics - Sun: atmospheric motions
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Crystal Growth, Thermal, Mechanical and Optical Properties of a New Organic Nonlinear Optical Material: Ethyl P-Dimethylamino Benzoate (EDMAB)
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作者 V. Natarajan J. Kalyana Sundar +4 位作者 P. Selvarajan M. Arivanandhan K. Sankaranarayanand S. Natarajan Y. Hayakawa 《Journal of Minerals and Materials Characterization and Engineering》 2011年第1期1-11,共11页
An organic material, namely, ethyl p-dimethylamino benzoate was crystallized for the first time by solution growth technique using pure and mixed solvents. Growth kinetics and morphology changes with solvents were inv... An organic material, namely, ethyl p-dimethylamino benzoate was crystallized for the first time by solution growth technique using pure and mixed solvents. Growth kinetics and morphology changes with solvents were investigated based on solute –solvent interactions of pure and mixed solvents. An appropriate mixed solvent for high quality crystals with well-defined morphology is reported. The absence of solvent molecules and the presence of various functional groups of the grown sample were qualitatively confirmed by FTIR spectroscopic studies. Thermal properties of the grown sample were analyzed by TG and DTA analysis. Mechanical properties of the EDMAB crystal were investigated by micro hardness studies. Moreover, the grown crystal shows high transparency in the visible and near IR regions. The material shows relatively high SHG efficiency than that of KDP. 展开更多
关键词 ORGANIC compounds Crystal growth - optical properties
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New Pyrometer with Double Y-type Optical Fibers
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作者 SHI Weidong, LI Zhiquan, TANG Xuhui, JIANG Wanlu(Yanshan University, Qinhuangdao 066004, CHN) 《Semiconductor Photonics and Technology》 CAS 1997年第1期40-43,49,共5页
Abstract: A new pyrometer, which can solve the affection of emissivity change in temperature measuring, has been developed by double Y - type optical fibers. The mathematical model of the new pyrometer is presented an... Abstract: A new pyrometer, which can solve the affection of emissivity change in temperature measuring, has been developed by double Y - type optical fibers. The mathematical model of the new pyrometer is presented and the errors of the new pyrometer are analyzed. 展开更多
关键词 EMISSIVITY Double Y - type optical Fibers PYROMETER
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A NEW OPTICALLY ACTIVE POLYURETHANE DERIVED FROM CHIRAL(2R,3R)(+)-DIETHYL L-TARTRATE AND DIISOCYANATE
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作者 陈传福 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 1999年第4期371-373,共3页
Optically active polyurethane was synthesized by the polyaddition of (2R, 3R)-(+)-diethyl L-tartrate (DET), 4,4'-diphenylmethane diisocyanate (MDI) and polyethylene glycol (PEG) with various molecular weights at 6... Optically active polyurethane was synthesized by the polyaddition of (2R, 3R)-(+)-diethyl L-tartrate (DET), 4,4'-diphenylmethane diisocyanate (MDI) and polyethylene glycol (PEG) with various molecular weights at 60 degrees C in DMSO. The polymers were characterized by specific rotation, DSC and H-1 NMR spectra. 展开更多
关键词 (2R 3R)-(+)-diethyl L-tartrate optically active polyurethane
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Optical and near-infrared photometric study of NGC 6724
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作者 Reda Bendary Ashraf Tadross +2 位作者 Priya Hasan Anas Osman Ahmed Essam 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2018年第2期37-42,共6页
BVRI CCD photometry of the poorly studied open cluster NGC 6724 has been carried out down to a limiting magnitude of V-20 mag. The stars of the cluster have been observed using the Newtonian focus (f/4.84) of the 74... BVRI CCD photometry of the poorly studied open cluster NGC 6724 has been carried out down to a limiting magnitude of V-20 mag. The stars of the cluster have been observed using the Newtonian focus (f/4.84) of the 74-inch telescope at Kottamia Astronomical Observatory in Egypt. Also, the 2MASS - JHK system is used to confirm the results we obtained. The main photometric parameters have been estimated for the present object; the diameter is found to be 6 arcmin, the distance is 15304-60pc from the Sun and the age is 900+50Myr. The optical reddening E(B - V) = 0.65 mag, while the infrared reddening is E(J - H) = 0.20 mag. The slope of the mass function distribution and the relaxation time estimations indicate that cluster NGC 6724 is dynamically relaxed. 展开更多
关键词 Milky Way -- open clusters and associations: individual (NGC 6724) - optical photom-etry - IR photometry - color-magnitude diagrams
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Nonlinear Optical Properties and Optical Limiting Measurements of {(1Z)-[4-(Dimethylamino)Phenyl]Methylene} 4-Nitrobenzocarboxy Hydrazone Monohydrate under CW Laser Regime
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作者 Fryad Z. Henari P. S. Patil 《Optics and Photonics Journal》 2014年第7期182-188,共7页
We report results from the investigation of the nonlinear refractive index and nonlinear absorption coefficient of {(1Z)-[4-(Dimethylamino)phenyl]methylene} 4-nitrobenzocarboxy hydrazone mono-hydrate (DMPM4NBCHM) solu... We report results from the investigation of the nonlinear refractive index and nonlinear absorption coefficient of {(1Z)-[4-(Dimethylamino)phenyl]methylene} 4-nitrobenzocarboxy hydrazone mono-hydrate (DMPM4NBCHM) solution using Z-scan technique with a continuous wave (CW) Argon ion laser. The results show that this type of organic material has a large nonlinear absorption and nonlinear refractive index at 488 nm and 514 nm. The origin of the nonlinear effects was discussed. We demonstrate that the light induced nonlinear refractive index variation, leads to limiting effect. The results indicated that DMPM4NBCHM could be promising candidates for application on nonlinear photonic devices and optical limiters. 展开更多
关键词 NONLINEAR Absorption NONLINEAR Refractive Index Z Scan optical Limiting {(Z)-[4-(Dimethylamino)Phenyl]Methylene} 4-Nitrobenzocarboxy Hydrazone MONOHYDRATE
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Design and experimental test of an optical vortex coronagraph
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作者 Cheng-Chao Liu De-Qing Ren +1 位作者 Yong-Tian Zhu Jiang-Pei Dou 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2017年第6期101-106,共6页
Using an optical vortex coronagraph (OVC) is one of the most promising techniques for di- rectly imaging exoplanets because of its small inner working angle and high throughput. This paper presents the design and la... Using an optical vortex coronagraph (OVC) is one of the most promising techniques for di- rectly imaging exoplanets because of its small inner working angle and high throughput. This paper presents the design and laboratory demonstration performance of an OVC based on liquid crystal polymers (LCPs) at 633 nm and 1520 nm. The OVC can deliver good performance in laboratory tests and achieve a contrast of 10-6 at an angular distance of 3A/D, which can be implemented for imaging young giant exoplanets in combination with extreme adaptive optics. 展开更多
关键词 INSTRUMENTATION coronagraph- techniques optical vortex - methods LABORATORY
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Strain effects on optical polarisation properties in (11■2) plane GaN films
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作者 郝国栋 陈涌海 +2 位作者 范亚明 黄晓辉 王怀兵 《Chinese Physics B》 SCIE EI CAS CSCD 2010年第11期542-547,共6页
We present the theoretical results of the electronic band structure of wurtzite GaN films under biaxial strains in the (11^-22)-plane. The calculations are performed by the k.p perturbation theory approach through u... We present the theoretical results of the electronic band structure of wurtzite GaN films under biaxial strains in the (11^-22)-plane. The calculations are performed by the k.p perturbation theory approach through using the effectivemass Hamiltonian for an arbitrary direction. The results show that the transition energies decrease with the biaxial strains changing from -0.5% to 0.5%. For films of (11^-22)-plane, the strains are expected to be anisotropic in the growth plane. Such anisotropic strains give rise to valence band mixing which results in dramatic change in optical polarisation property. The strain can also result in optical polarisation switching phenomena. Finally, we discuss the applications of these properties to the (1132) plane GaN-based light-emitting diode and lase diode. 展开更多
关键词 GAN (11-22)-plane STRAIN optical anisotropy
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Optically Powered Temperature Measuring Instrument for Big Rotor
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作者 ZHENG Dezhong(Yanshan University, Qinhuandao 066004, CHN) 《Semiconductor Photonics and Technology》 CAS 1997年第1期35-39,共5页
Abstract: A micro - power consumption non - contact temperature measuring instrument for big rotor is introduced. As it solves very well the signal coupling under high speed rotation and power supply problem for probe... Abstract: A micro - power consumption non - contact temperature measuring instrument for big rotor is introduced. As it solves very well the signal coupling under high speed rotation and power supply problem for probe, the instrument can realize persistent on - line temperature measurement for big rotor drived by the ordinary light transmitted by optical fiber under the room light. 展开更多
关键词 Non - contact Measurement optical Fiber ROTOR SemiconductorThermistor
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New Measuring Temperature Setup with Optical Probe
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作者 HOU Peiguo, LIU Jianming(Yanshan University, Qinbuangdao 066004, CHN ) 《Semiconductor Photonics and Technology》 CAS 1997年第1期71-73,共3页
Abstract: A new setup of measuring temperature is developed, which the probe is a micro- power consumptive one with CMOS circuit and is driven by optical power. For transmitting the measured signal and optical power s... Abstract: A new setup of measuring temperature is developed, which the probe is a micro- power consumptive one with CMOS circuit and is driven by optical power. For transmitting the measured signal and optical power signal in a long distance, the fiber technology is applied in this setup. 展开更多
关键词 Micro - power Consumptive Probe optical Fiber Transmission Sen-sors Temperature Measurement
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PAD Spectrometer Based on Wide Tunable Optical Parametric Oscillator for Noninvasive Medical Diagnostics
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作者 D. B. Kolker I. V. Sherstov +9 位作者 A. I. Karapuzikov A. A. Karapuzikov A. A. Boyko M. K.Starikova N. Yu. Dukhovnikova V. N. Loconov M. Yu. Shtyrov I. B. Miroshnichenko K. G. Zenov M. B. Miroshnichenko 《Optics and Photonics Journal》 2013年第2期43-46,共4页
The gas analyzer based on optical parametric oscillators (OPO) and laser photo - acoustic spectroscopy is demonstrated. The optical parametric oscillators based on fun – out PPLN and bulk crystal AgGaS2 with a two-pa... The gas analyzer based on optical parametric oscillators (OPO) and laser photo - acoustic spectroscopy is demonstrated. The optical parametric oscillators based on fun – out PPLN and bulk crystal AgGaS2 with a two-pass pumping are developed. Wide tunable OPO is pumped by compact nanosecond Nd: YLF laser. Pulse duration is 5 - 7 ns, maximum pulse energy is 1.5 mJ at a frequency of 100-2000 Hz. OPO lasing threshold is 10 - 16 mJ/cm2 at the spectral range 2.2 - 4 μm for fun – out PPLN OPO and 12 - 20 mJ/cm2 at the spectral range 4 - 7.5 μm for AgGaS2 OPO. Absorption spectra of gaseous mixtures (CH4, C3H8, C2H6, C2H4 and CO2) and human’s breath were studied. 展开更多
关键词 optical Parametric Oscillator Nonlinear optical Crystals Silver Thiogallate FUN out PPLN Photo - Acoustic Spectroscopy Absorption Spectrum
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Simulation of a ground-layer adaptive optics system for the Kunlun Dark Universe Survey Telescope
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作者 Peng Jia Sijiong Zhang 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2013年第7期875-884,共10页
Ground Layer Adaptive Optics (GLAO) is a recently developed technique extensively applied to ground-based telescopes, which mainly compensates for the wavefront errors induced by ground-layer turbulence to get an ap... Ground Layer Adaptive Optics (GLAO) is a recently developed technique extensively applied to ground-based telescopes, which mainly compensates for the wavefront errors induced by ground-layer turbulence to get an appropriate point spread function in a wide field of view. The compensation results mainly depend on the turbu-lence distribution. The atmospheric turbulence at Dome A in the Antarctic is mainly distributed below 15 meters, which is an ideal site for applications of GLAO. The GLAO system has been simulated for the Kunlun Dark Universe Survey Telescope, which will be set up at Dome A, and uses a rotating mirror to generate several laser guide stars and a wavefront sensor with a wide field of view to sequentially measure the wavefronts from different laser guide stars. The system is simulated on a computer and parameters of the system are given, which provide detailed information about the design of a practical GLAO system. 展开更多
关键词 instrumentation: adaptive optics - methods: numerical
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掺锶的偏硼酸钡(Sr_xBa_(1-x)B_2O_4)大块单晶的生长和表征 被引量:1
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作者 李敢生 吴喜泉 +2 位作者 吴少凡 俞振森 谢剑凌 《人工晶体学报》 EI CAS CSCD 北大核心 2000年第S1期123-,共1页
Barium metaborate (BaB 2O 4) exists in two forms the high temperature for m α phase and the low temperature form β phase,with the phase transition poi nt at around 925℃.The low temperature phase (β BBO) is an exce... Barium metaborate (BaB 2O 4) exists in two forms the high temperature for m α phase and the low temperature form β phase,with the phase transition poi nt at around 925℃.The low temperature phase (β BBO) is an excellent NLO cryst al for UV region,while the high temperature one (α BBO) is known as a good bir efringent material.α BBO crystal possesses better transparency in the ultravio let region compared with commonly used YVO 4 and CaCO 3 crystals.However,due t o phase transition problem,it is difficult to grow single α BBO crystals by D CZ method,which restricts its wider application.α BBO crystal usually cracks upon cooling resulted from phase transition to β phase.Therefore,it is difficult to grow β BBO single crystals directly from pure BaB 2O 4 mel t;however,to grow single crystals of α BBO is not easy,either. Our recent experiments showed that one could avoid cracking of α BBO cryst als by Sr 2+ doping.This minute amount of Sr 2+ plays the role of structure stabilizer,which inhibits structural reconstruction. In this way,Sr 2+ d op ed BBO single crystals do not subject to phase transition from 925℃ down to roo m temperature. We have mow successfully grown out α BBO single crystals 30mm in diameter by D CZ method from Sr x Ba 1- x BO 4 melt with Sr concentration 0.3 0 .5%.The ratation rate is 10 15r/min,pulling speed is 1 2mm/h.Preliminary tests revealed that its structure and physic chemical properties were almost identic al to those grown from pure melts.These Sr 2+ doped α BBO crystals are no w being widely used in optical isolators. 展开更多
关键词 Sr x Ba 1- x B 2O 4 crystal nonlinear optical crystal birefractiv e crystal CZ method
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The Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST) 被引量:44
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作者 Xiang-Qun Cui Yong-Heng Zhao +52 位作者 Yao-Quan Chu Guo-Ping Li Qi Li Li-Ping Zhang Hong-Jun Su Zheng-Qiu Yao Ya-Nan Wang Xiao-Zheng Xing Xin-Nan Li Yong-Tian Zhu Gang Wang Bo-Zhong Gu A-Li Luo Xin-Qi Xu Zhen-Chao Zhang Gen-Rong Liu Hao-Tong Zhang De-Hua Yang Shu-Yun Cao Hai-Yuan Chen Jian-Jun Chen Kun-Xin Chen Ying Chen Jia-Ru Chu Lei Feng Xue-Fei Gong Yong-Hui Hou Hong-Zhuan Hu Ning-Sheng Hu Zhong-Wen Hu Lei Jia Fang-Hua Jiang Xiang Jiang Zi-Bo Jiang Ge Jin Ai-Hua Li Yan Li Ye-Ping Li Guan-QunLiu Zhi-Gang Liu Huo-Ming Shi Zheng-Hong Tang Qing-Sheng Tao Xiang-Yan Yuan Chao Zhai Jing Zhang Yan-Xia Zhang Yong Zhang Ming Zhao Fang Zhou Guo-Hua Zhou Jie Zhu Si-Cheng Zou 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2012年第9期1197-1242,共46页
The Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST, also called the Guo Shou Jing Telescope) is a special reflecting Schmidt telescope. LAMOST’s special design allows both a large aperture (effecti... The Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST, also called the Guo Shou Jing Telescope) is a special reflecting Schmidt telescope. LAMOST’s special design allows both a large aperture (effective aperture of 3.6 m–4.9 m) and a wide field of view (FOV) (5°). It has an innovative active reflecting Schmidt configuration which continuously changes the mirror’s surface that adjusts during the observation process and combines thin deformable mirror active optics with segmented active optics. Its primary mirror (6.67m×6.05 m) and active Schmidt mirror (5.74m×4.40 m) are both segmented, and composed of 37 and 24 hexagonal sub-mirrors respectively. By using a parallel controllable fiber positioning technique, the focal surface of 1.75 m in diameter can accommodate 4000 optical fibers. Also, LAMOST has 16 spectrographs with 32 CCD cameras. LAMOST will be the telescope with the highest rate of spectral acquisition. As a national large scientific project, the LAMOST project was formally proposed in 1996, and approved by the Chinese government in 1997. The construction started in 2001, was completed in 2008 and passed the official acceptance in June 2009. The LAMOST pilot survey was started in October 2011 and the spectroscopic survey will launch in September 2012. Up to now, LAMOST has released more than 480 000 spectra of objects. LAMOST will make an important contribution to the study of the large-scale structure of the Universe, structure and evolution of the Galaxy, and cross-identification of multiwaveband properties in celestial objects. 展开更多
关键词 techniques: wide field telescope - active optics - multi fiber - spectroscopy survey - data reduction
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聚3-己基噻吩/ZnO微纳米球复合膜的形貌和光学性能
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作者 孟甲 李勇 许并社 《太原理工大学学报》 CAS 北大核心 2015年第1期29-34,共6页
对ZnO微纳米球从分散性和能级匹配方面进行了受体可行性研究,分析了能级结构和光电性能之间的关系;并将聚-3己基噻吩(P3HT)与ZnO微纳米球共混和旋涂制备P3HT/ZnO复合膜,考察P3HT和ZnO的共混质量比和退火温度对复合膜微观形貌及光学性能... 对ZnO微纳米球从分散性和能级匹配方面进行了受体可行性研究,分析了能级结构和光电性能之间的关系;并将聚-3己基噻吩(P3HT)与ZnO微纳米球共混和旋涂制备P3HT/ZnO复合膜,考察P3HT和ZnO的共混质量比和退火温度对复合膜微观形貌及光学性能的影响。结果说明,P3HT/ZnO微纳米球复合膜与纯ZnO薄膜相比,拓宽了紫外吸收范围,增强了对太阳光的吸收,说明复合膜的吸收光谱与太阳光谱能够较好的匹配;在120℃退火处理后增强了P3HT的有序性,改善了复合膜的结晶性,有利于电池效率的提高。当P3HT质量浓度为6mg/mL、旋涂转速为1 500r/min时,优质复合膜的制备参数为:P3HT和ZnO微纳米球共混质量比为1∶2,退火温度120℃。优质复合膜大大拓宽了紫外吸收范围,增强了对太阳光的吸收。 展开更多
关键词 ZnO微纳米球 -3己基噻吩 有机/无机杂化复合膜 光学性能
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Targeting 14-3-3 adaptor protein-protein interactions to stimulate central nervous system repair 被引量:2
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作者 Andrew Kaplan Alyson E.Fournier 《Neural Regeneration Research》 SCIE CAS CSCD 2017年第7期1040-1043,共4页
The goal of developing treatments for central nervous system(CNS)injuries is becoming more attainable with the recent identification of various drugs that can repair damaged axons.These discoveries have stemmed from... The goal of developing treatments for central nervous system(CNS)injuries is becoming more attainable with the recent identification of various drugs that can repair damaged axons.These discoveries have stemmed from screening efforts,large expression datasets and an improved understanding of the cellular and molecular biology underlying axon growth.It will be important to continue searching for new compounds that can induce axon repair.Here we describe how a family of adaptor proteins called 14-3-3s can be targeted using small molecule drugs to enhance axon outgrowth and regeneration.14-3-3s bind to many functionally diverse client proteins to regulate their functions.We highlight the recent discovery of the axon-growth promoting activity of fusicoccin-A,a fungus-derived small molecule that stabilizes 14-3-3 interactions with their client proteins.Here we discuss how fusicoccin-A could serve as a starting point for the development of drugs to induce CNS repair. 展开更多
关键词 axon regeneration 14-3-3 gcnl fusicoccin optic nerve spinal cord injury
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One-dimensional Supramolecular Chain Based on a Dinuclear Terbium(Ⅲ) 4-Cyanobenzoate Complex 被引量:1
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作者 李国清 李艳 +4 位作者 邹文强 陈其湧 吴阿清 郑发鲲 郭国聪 《Chinese Journal of Structural Chemistry》 SCIE CAS CSCD 北大核心 2007年第7期805-810,共6页
A new dinuclear Tb(Ⅲ) 4-cyanobenzoate complex [Tb2(4-cba)6(phen)2] (4-Hcba = 4-cyanobenzoic acid and phen = 1,10-phenanthroline) 1 has been synthesized by solvothermal reaction in an ethanol/water mixed solut... A new dinuclear Tb(Ⅲ) 4-cyanobenzoate complex [Tb2(4-cba)6(phen)2] (4-Hcba = 4-cyanobenzoic acid and phen = 1,10-phenanthroline) 1 has been synthesized by solvothermal reaction in an ethanol/water mixed solution at 100℃ and structurally characterized by single-crystal X-ray diffraction. Crystallographic data: C72H40N10O12Tb2, Mr=1554.98, triclinic Pi, a = 9.903(3), b = 11.769(8), c = 15.078(8)A, a = 111.42(12), It = 96.37(19), γ = 101-24(14)°, V= 1572(1)A3, Z= 1, Dc = 1.642 g/cm^3, F(000) = 768 μ = 2.305 mm^-1, the final R = 0.0205 and wR = 0.0543 for 5479 reflections with I 〉 2σ(I). Structural analysis shows that 1 displays an isolated dinuclear structure. Two eight-coordinated Tb(Ⅲ) ions are bridged by four 4-cba ligands in the syn-syn bidentate coordination mode, and two other 4-cba ligands chelate these two Tb(Ⅲ) ions. The title complex molecules are connected through π-π stacking interactions to generate a one-dimensional supramolecular chain, The characteristic infrared spectra, luminescent properties and thermogravimetric analyses have also been discussed. 展开更多
关键词 terbium(Ⅲ) complex 4-cyanobenzoic add crystal structure π-π stacking optical spectroscopy
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