Clinical effects of nonconvulsive electrotherapy combined with mindfulness-based stress reduction and changes of serum inflammatory factors in depression

BACKGROUND Depression is a common and serious psychological condition,which seriously affects individual well-being and functional ability.Traditional treatment methods include drug therapy and psychological counseling;however,these methods have different degrees of side effects and limitations.In recent years,nonconvulsive electrotherapy(NET)has attracted increasing attention as a noninvasive treatment method.However,the clinical efficacy and potential mechanism of NET on depression are still unclear.We hypothesized that NET has a positive clinical effect in the treatment of depression,and may have a regulatory effect on serum inflammatory factors during treatment.AIM To assess the effects of NET on depression and analyze changes in serum inflammatory factors.METHODS This retrospective study enrolled 140 patients undergoing treatment for depression between May 2017 and June 2022,the observation group that received a combination of mindfulness-based stress reduction(MBSR)and NET treatment(n=70)and the control group that only received MBSR therapy(n=70).The clinical effectiveness of the treatment was evaluated by assessing various factors,including the Hamilton Depression Scale(HAMD)-17,self-rating idea of suicide scale(SSIOS),Pittsburgh Sleep Quality Index(PSQI),and levels of serum inflammatory factors before and after 8 wk of treatment.The quality of life scores between the two groups were compared.Comparisons were made using t and χ^(2) tests.RESULTS After 8 wk of treatment,the observation group exhibited a 91.43%overall effectiveness rate which was higher than that of the control group which was 74.29%(64 vs 52,χ^(2)=7.241;P<0.05).The HAMD,SSIOS,and PSQI scores showed a significant decrease in both groups.Moreover,the observation group had lower scores than the control group(10.37±2.04 vs 14.02±2.16,t=10.280;1.67±0.28 vs 0.87±0.12,t=21.970;5.29±1.33 vs 7.94±1.35,t=11.700;P both<0.001).Additionally,there was a notable decrease in the IL-2,IL-1β,and IL-6 in both groups after treatment.Furthermore,the observation group exhibited superior serum inflammatory factors compared to the control group(70.12±10.32 vs 102.24±20.21,t=11.840;19.35±2.46 vs 22.27±2.13,t=7.508;32.25±4.6 vs 39.42±4.23,t=9.565;P both<0.001).Moreover,the observation group exhibited significantly improved quality of life scores compared to the control group(Social function:19.25±2.76 vs 16.23±2.34;Emotions:18.54±2.83 vs 12.28±2.16;Environment:18.49±2.48 vs 16.56±3.44;Physical health:19.53±2.39 vs 16.62±3.46;P both<0.001)after treatment.CONCLUSION MBSR combined with NET effectively alleviates depression,lowers inflammation(IL-2,IL-1β,and IL-6),reduces suicidal thoughts,enhances sleep,and improves the quality of life of individuals with depression.

Intervention effect of mindfulness-based stress reduction for psychological health among nurses:A meta-analysis

Objective:To systematically evaluate the effects of MBSR on psychological health intervention in nurses.Methods:The randomized controlled trial(RCT)and self-controlled trial(SC)investigating the application of mindfulness-based stress reduction in nursing staff were retrieved from CNKI,WanFang,VIP,PubMed,Cochrane Library,Web of Science,EMBASE databases.The retrieval time was set from the establishment of the database to April 2020.The Review Manager 5.3 software were used for meta-analysis.Result:9 RCTs and 5 self-control trails were included with 1421,712 subjects in the experimental group and 709 subjects in the control group.The results of the meta-analysis showed that compared with the control group,mindfulness-based stress reduction therapy can effectively reduce the psychological symptoms of clinical nurses[SMD=-0.96,95%CI(-1.51,-0.38),P=0.001],reduces nurses'anxiety levels[SMD=-1.28,95%CI(-2.18,-0.38),P=0.005],relieve the nurse's depression[SMD=-1.08,95%CI(-2.15,-0.02),P=0.005],improve the mental resilience of nurse[SMD=7.05,95%CI(3.93,10.17),P=0.03],showing a statistical meaning.Conclusion:The mental health of nurses is often neglected by themselves and there is insufficient awareness that MBSR can improve mental health.There has been a debate about whether MBSR actually improves the mental health of nurses,so it is necessary to further explore this issue and seek better methods and opportunities for practice.

Effects of mindfulness-based stress reduction therapy on anxiety and depression in patients with maintenance hemodialysis:a meta analysis

Objective:This study aimed to evaluate the effects of mindfulness-based stress reduction therapy on anxiety and depression in patients with maintenance hemodialysis.Methods:CNKI,VIP,WanFang,CBM,Embase,the Cochrane Library and PubMed databases were retrieved.Randomized controlled trials of intervention effects of mindfulness-based stress reduction combined with conventional hemodialysis education compared with conventional hemodialysis education on maintenance hemodialysis patients were collected.The retrieval period was from the establishment of the database to December 2019.Two researchers independently screened the literatures,extracted the data and evaluated the risk of bias in the included studies.RevMan 5.3 software was used for analysis.Results:A total of 9 studies,which comprised a total of 664 participants were included in the final meta analysis.The results showed that mindfulness-based stress reduction could reduce the anxiety of patients(SMD=?1.65,95%CI:?2.29 to?1.01),reduce the depression(SMD=?1.44,95%CI:?1.85 to?1.03).Conclusion:Mindfulness-based stress reduction therapy has positive effects on depression,anxiety in patients with maintenance hemodialysis.

Influence of standardized nursing intervention combined with mindfulness stress reduction training on the curative effect in patients with acute pancreatitis

BACKGROUND Acute pancreatitis(AP)is a common inflammatory disease of the pancreas with high mortality rates.It is of great significance to take scientific intervention measures for patients with AP in time.AIM To explore the effect of standardized nursing combined with mindfulness stress reduction training on the curative effect,negative emotion,and quality of life in patients with acute pancreatitis.METHODS A total of 80 patients with acute pancreatitis admitted to The First People's Hospital of Jiangxia District Hospital from May 2021 to May 2023 were randomly divided into control group and observation group(n=40).Patients in control group were given the standardized nursing intervention,and the observation group were given standardized nursing plus mindfulness stress reduction training intervention.The time of clinical symptom disappeared or improved,complication occurrence rate,emotional state,and quality of life score of the two groups were observed and compared.RESULTS In comparison with the control group,the bowel sound recovery time,ventosity and abdominal pain improvement time,and venting and cacation time in observation group were shorter,and the total incidence rate of complications was reduced,showing statistically significant difference(P<0.05).The scores of anxiety and depression in observation group were lower than those in control group(P<0.05).Serum levels of tumour necrosis factor alpha,interleukin(IL)-6,IL-1βand IL-8 in observation group were lower than those in control group(P<0.05).The scores of life quality in physiology,psychology,environment and social relations in observation group were higher than those in control group,and the differences were statistically significant(P<0.05).CONCLUSION The application of standardized nursing intervention combined with mindfulness stress reduction training in patients with acute pancreatitis has a definite effect,which can help to ameliorate the clinical symptoms,anxiety and depression of patients,reduce the incidence rate of complications,and improve the prognosis of patients.

Research progress on the effects of positive stress reduction on positive awareness and psychosocial functioning in patients with depressive disorders

To review the current research status of positive thought stress reduction therapy(PTSRT),psychosocial functioning of patients with depressive disorders,the shortcomings and outlook of the influence of PTSRT on positive thought awareness,and psychosocial functioning of patients with depressive disorders.This review has the objective to provide clinical healthcare personnel with essential information about the use of PTSRT to improve the level of positive thought and psychosocial functioning of patients with depressive disorders.

Simulation of thermal and sodium expansion stress in aluminum reduction cells

Two finite element(FE) models were built up for analysis of stress field in the lining of aluminum electrolysis cells.Distribution of sodium concentration in cathode carbon blocks was calculated by one FE model of a cathode block.Thermal stress field was calculated by the other slice model of the cell at the end of the heating-up.Then stresses coupling thermal and sodium expansion were considered after 30 d start-up.The results indicate that sodium penetrates to the bottom of the cathode block after 30 d start-up.The semi-graphitic carbon block has the largest stress at the thermal stage.After 30 d start-up the anthracitic carbon has the greatest sodium expansion stress and the graphitized carbon has the lowest sodium expansion stress.Sodium penetration can cause larger deformation and stress in the cathode carbon block than thermal expansion.

Bayesian partial pooling to reduce uncertainty in overcoring rock stress estimation

The state of in situ stress is a crucial parameter in subsurface engineering,especially for critical projects like nuclear waste repository.As one of the two ISRM suggested methods,the overcoring(OC)method is widely used to estimate the full stress tensors in rocks by independent regression analysis of the data from each OC test.However,such customary independent analysis of individual OC tests,known as no pooling,is liable to yield unreliable test-specific stress estimates due to various uncertainty sources involved in the OC method.To address this problem,a practical and no-cost solution is considered by incorporating into OC data analysis additional information implied within adjacent OC tests,which are usually available in OC measurement campaigns.Hence,this paper presents a Bayesian partial pooling(hierarchical)model for combined analysis of adjacent OC tests.We performed five case studies using OC test data made at a nuclear waste repository research site of Sweden.The results demonstrate that partial pooling of adjacent OC tests indeed allows borrowing of information across adjacent tests,and yields improved stress tensor estimates with reduced uncertainties simultaneously for all individual tests than they are independently analysed as no pooling,particularly for those unreliable no pooling stress estimates.A further model comparison shows that the partial pooling model also gives better predictive performance,and thus confirms that the information borrowed across adjacent OC tests is relevant and effective.

Properties and appropriate conditions of stress reduction factor and thermal shock resistance parameters for ceramics

Through introducing the analytical problem of the plate with convection into the solution of the transient heat conduction thermal stress field model of the elastic plate, the stress reduction factor is presented explicitly in its dimensionless form. A new stress reduction factor is introduced for the purpose of comparison. The proper- ties and appropriate conditions of the stress reduction factor, the first and second ther- mal shock resistance （TSR） parameters for the high and low Biot numbers, respectively, and the approximation formulas for the intermediate Blot number-interval are discussed. To investigate the TSR of ceramics more accurately, it is recommended to combine the heat transfer theory with the theory of thermoelasticity or fracture mechanics or use a numerical method. The critical rupture temperature difference and the critical rup- ture dimensionless time can be used to characterize the TSR of ceramics intuitively and legibly.

Reduction and compensation of lattice stress in high energy P^+ and P+Sb implanted silicon

The relations of variation of lattice stress to shape, peak concentrations of the P atom depth profile and Sb doses of P+Sb dual implantation were studied in high energy P implantation silicon. The experimental results show that the lattice stress in P-implanted silicon obviously increases with increasing ion dose. The stress of P-implanted silicon with the dose of 2×1013/cm2 is 2.2 times greater than at a dose of 3.6×1012/cm2. The stress decreases rapidly as the annealing time increases.It is very interesting that the stress has a negative value when the concentration of P atoms in the implanted layer is below 6×1016/cm3, whereas the stress becomes positive when the concentration is greater than 6×16/cm3. The stress increases rapidly with increasing Sb ion dose after P implantation. The stress has a positive value before annealing. If the Sb dose is below 1 ×1016/cm2, the stress is negative after annealing,and it is positive when the Sb dose is higher than 1×1016/cm2. The stress is close to zero for a Sb implantation dose of 1×1016/cm2. The best compensation dose of Sb to P implantation dose of 3×1016/cm2 is 1×1016/cm2.

Mindfulness-based cognitive therapy in the intervention of psychiatric disorders: A review

Mindfulness-based cognitive therapy(MBCT)is frequently used for psychiatric disorders.Despite MBCT’s considerable potential for improving psychological health for patients,there is little empirical evidence to support its practical application in Chinese.This review will define meditation and mindfulness,provide an overview of the development of MBCT,identify the evidence for the effectiveness of MBCT,and offer recommendations to medical personnels on how to provide support for patients receiving mindfulness intervention.

Characteristics and mechanism investigation on drag reduction of oblique riblets

This work primarily focuses on the drag reduction characteristics and mechanism investigation of oblique riblets. First, a calculation model of the oblique riblets surface is established, and Reynolds stress model(RSM) turbulence model is used for numerical simulation of the oblique riblets flow field. Subsequently, the influence of inclination angle between flow direction and arrangement direction of riblets on friction resistance and drag reduction rate is further analyzed. Through the investigation of the distribution of shear stress, pressure stress and velocity in oblique riblets boundary layer, the oblique riblets drag reduction mechanism is finally revealed. Results show that, with increase of velocity and inclination angle, the pressure resistance increases obviously, along with the decreasing of the viscous resistance distinctly. The maximum drag reduction rate of the oblique riblets is 7.33%. Moreover, when the inclination angle increases, the wall shear stress reduces on oblique riblets surface; while differential pressure increases at both sides of oblique riblets tips. In addition, when inclination angle is small, the secondary vortex at oblique riblets tips will disappear soon. New vortices will be formed inside the oblique riblets and cause the decrease of viscosity resistance. Thus, oblique riblets show a better drag reduction effect and have an effective control on boundary layer.

Research Findings Using Mindfulness-Based Interventions for Chronic Pain

Chronic pain is a complex condition that is very detrimental to physical and psychological wellbeing. It carries a significant level of disability and economic burden. Pain patients frequently experience comorbid mental illness (e.g. depression, anxiety, PTSD, insomnia) and often require psychotherapeutic interventions in addition to medication management. Mindfulness-based interventions (MBIs) have emerged as a means to treat several chronic conditions (e.g. chronic pain, depression, anxiety, substance abuse, stress, insomnia). The objective of this review is to evaluate the current research on the use of MBIs in chronic pain managment. Although there are several controlled trials on the use of MBIs in chronic pain management, only a few studies were found that demonstrated significant effects on pain intensity, quality of life, as well as physical and psychological functioning. Therefore, the current evidence is mixed and there are insufficient data to definitively confirm the full impact of the use of MBIs in chronic pain conditions such as fibromyalgia, chronic low back pain, rheumatoid arthritis, and chronic musculoskeletal pain. The lack of compelling evidence at this time signals a demand for higher quality investigations in this area. Research examining MBIs and concomitant CBT may be of great value in order to synergize and strengthen patient outcomes.

Drag reduction by linear viscosity model in turbulent channel flow of polymer solution

A further numerical study of the theory that the drag reduction in the turbulence is related to the viscosity profile growing linearly with the distance from the wall was performed.The constant viscosity in the Navier-Stokes equations was replaced using this viscosity model.Some drag reduction characteristics were shown comparing with Virk's phenomenology.The mean velocity and Reynolds stress profiles are consistent with the experimental and direct numerical simulation results.A drag reduction level of 45% was obtained.It is reasonable for this linear viscosity model to explain the mechanism of turbulence drag reduction in some aspects.

Antioxidant-induced reductive stress has untoward consequences on the brain microvasculature

All cells in the body metabolize oxygen in a series of reactions in the mitochondria to generate energy.A by-product of these reactions is the production of highly reactive oxygen radicals which have the potential to cause irreparable damage to cellular components,and have been linked to mutagenic and neurotoxicity of the nervous system.Under normal conditions,innate molecular systems,glutathione,superoxide dismutases,

基于ELM的超声多特征融合螺栓应力测量方法

针对传统超声波螺栓应力测量中存在的非线性和不适定性问题,提出一种基于极限学习机(ELM)的超声多特征融合螺栓应力测量方法。首先基于声弹性理论和散射理论,根据超声回波信号提取声时差及瑞利散射范围内多晶体材料中纵波的衰减系数等超声波特征参数。然后通过向量降维选择声时差、衰减系数和有效受力长度作为模型输入特征向量,建立了基于ELM的超声多特征融合螺栓应力测量模型。搭建螺栓轴向应力超声波测量实验平台,对不同材料和规格的螺栓进行螺栓应力的测量,并对比了使用传统的超声测量方法的测量结果,验证了传统超声检测方法的局限性。对比了ELM与其他机器学习方法包括BP、支持向量回归(SVR)的测量结果和精度。结果表明,提出的方法有效克服了传统超声测量方法的不足,能实现不同材料不同规格的螺栓应力测量,并且测量精度更高(平均相对误差为3.86%),泛化能力更好。

正念减压联合多模式镇痛在膝/髋关节置换病人中的应用

目的:探讨正念减压联合多模式镇痛对膝/髋关节置换病人的应用效果。方法:选取2021年7月—2023年6月在我院骨关节外科行膝/髋关节置换的80例病人为研究对象,随机分为对照组和试验组各40例。对照组给予多模式镇痛,试验组给予正念减压联合多模式镇痛的镇痛方式。比较两组干预后的正念水平、焦虑情况、生活质量、关节炎症状、疼痛程度及生活质量。结果:干预后,试验组焦虑自评量表(SAS)、骨关节炎指数(WOMAC)、数字疼痛评分表(NRS)评分低于对照组,QoR-40术后康复质量评分量表、五因素正念量表(FFMQ)、健康调查简表(SF-36)评分高于对照组,差异均有统计学意义(P<0.05)。结论:正念减压联合多模式镇痛可以缓解膝/髋关节置换病人疼痛、焦虑及骨关节炎症状,提高病人正念水平及生活质量。

正念减压训练结合纽曼系统干预在肝癌手术患者中的应用

目的 探讨正念减压训练结合纽曼系统干预在肝癌手术患者中的应用效果。方法 将135例肝癌手术患者按随机数字表法分为观察组、对照A组、对照B组,每组45例。对照A组采取正念减压训练,对照B组采取纽曼系统干预,观察组采取正念减压训练结合纽曼系统干预。比较3组患者术后康复情况、心理状态[简式简明心境问卷(POMS-SF)]、创伤后应激障碍[创伤后应激障碍自评量表(PCL-C)]及术后寒战发生情况。结果 观察组患者术后首次排气时间、首次排便时间、首次进食时间、首次下床时间及术后住院时间均短于对照A组、对照B组,差异均有统计学意义(P﹤0.05)。干预后,观察组、对照A组患者POMS-SF量表各维度评分均较干预前降低,且观察组患者POMS-SF量表各维度评分均低于对照A组、对照B组,对照A组患者POMS-SF量表各维度评分均低于对照B组,差异均有统计学意义(P﹤0.05)。干预后,3组患者PCL-C量表各维度评分均较干预前降低,且观察组患者PCL-C量表各维度评分均低于对照A组、对照B组,差异均有统计学意义(P﹤0.05)。观察组、对照B组患者术后寒战发生率均低于对照A组,差异均有统计学意义(P﹤0.05)。结论 正念减压训练结合纽曼系统干预有助于调节肝癌手术患者的心理状态,减轻创伤后应激障碍,减少术后寒战,促进术后早期康复。

正念减压联合分阶段康复护理对喉癌喉部分切除术后患者吞咽功能及负性情绪的影响

目的考察正念减压联合分阶段康复护理对喉癌喉部分切除术后患者吞咽功能及负性情绪的影响。方法90例行喉癌喉部分切除术患者,随机分为对照组和观察组,各45例。对照组给予常规护理干预方法,观察组给予正念减压联合分阶段康复护理方法。比较两组患者吞咽功能、心理状态、癌因性疲乏和生活质量、并发症发生情况。结果干预后8周,两组标准吞咽功能评价量表(SSA)评分均低于干预前和干预后4周,中文版安德森吞咽困难量表(MDADI)评分均高于干预前和干预后4周,且干预后4周,两组SSA评分均低于干预前,MDADI评分均高于干预前(P<0.05)。干预后4、8周,观察组SSA评分分别为(10.41±1.88)、(8.72±1.25)分,均低于同期对照组的(11.51±1.67)、(9.63±1.19)分,MDADI评分分别为(65.41±5.33)、(75.82±5.13)分,均高于对照组的(62.81±5.67)、(73.42±5.50)分(P<0.05)。干预后8周,两组抑郁自评量表(SDS)、焦虑自评量表(SAS)评分均低于干预前和干预后4周,且干预后4周,两组SAS、SDS评分均低于干预前(P<0.05)。干预后4、8周观察组SAS、SDS评分均低于同期对照组(P<0.05)。干预后8周,两组Piper疲乏修订量表(PFS)均低于干预前和干预后4周,头颈部癌生命质量测定量表(QLICP-HN)评分均高于干预前和干预后4周,且干预后4周,两组PFS评分均低于干预前,QLICP-HN评分均高于干预前(P<0.05)。干预后4、8周,观察组PFS评分均低于同期对照组,QLICP-HN评分均高于同期对照组(P<0.05)。观察组并发症发生率6.67%低于对照组的22.22%(P<0.05)。结论正念减压联合分阶段康复护理能够有效改善喉癌喉部分切除术后患者的吞咽功能和负性情绪,缓解癌因性疲乏,提高生活质量,降低并发症发生情况。

正念减压疗法在大隐静脉曲张伴睡眠障碍患者围术期中的应用效果

目的探究正念减压疗法在大隐静脉曲张伴睡眠障碍患者围术期中的应用效果。方法选取2020年1月—2022年6月收治的90例大隐静脉曲张伴睡眠障碍,采用随机数字表法随机将其分为试验组和对照组2组各45例。试验组围术期在常规治疗基础上给予正念减压疗法,对照组围术期给予常规治疗。比较2组入院当天和出院当天应对方式(采用简易应对方式问卷评估)、心理状态[采用焦虑自评量表(SAS)及抑郁自评量表(SDS)评估]和睡眠质量[采用匹兹堡睡眠质量指数量表(PSQI)评估],以及出院当天住院满意度。结果出院当天,2组积极应对评分、消极应对评分、SAS评分、SDS评分和PSQI评分均优于入院当天;试验组积极应对评分、消极应对评分、SAS评分、SDS评分、PSQI评分和住院满意度均优于对照组(P<0.05)。结论围术期实施正念减压疗法有助于改善大隐静脉曲张伴睡眠障碍患者应对方式、心理状态、睡眠质量,且患者住院满意度较高。

正念减压结合个体化护理在阻塞性睡眠呼吸暂停综合征患者中的应用效果

目的:分析正念减压和个体化护理联合用于阻塞性睡眠呼吸暂停综合征的价值。方法:选取2021年9月至2023年8月福建厦门大学附属第一医院肺科收治的阻塞性睡眠呼吸暂停综合征患者64例作为研究对象,随机分为观察组和对照组,每组32例。观察组采取正念减压和个体化护理,对照组行常规护理,对比满意度等指标。结果:关于FFMQ评分:干预结束时,观察组的数据比对照组高(P<0.05)。总有效率:观察组达到了96.87%,高于对照组的81.25%(P<0.05)。满意度:观察组为100.0%,高于对照组的81.25%(P<0.05)。结论:阻塞性睡眠呼吸暂停综合征联用正念减压和个体化护理,患者的满意度更高,正性情绪改善更加明显,护理效果提升更为迅速。