BACKGROUND Salivary gland tumors are relatively rare.Most minor salivary gland tumors are malignant with benign tumors accounting for 18%of the tumors.Pleomorphic adenoma(PA)is the most common salivary gland tumor.Lip...BACKGROUND Salivary gland tumors are relatively rare.Most minor salivary gland tumors are malignant with benign tumors accounting for 18%of the tumors.Pleomorphic adenoma(PA)is the most common salivary gland tumor.Lip PA is uncommon with 9.8%occurring in the upper lip.We are adding on the knowledge of the rare upper lip PA(benign mixed tumor).CASE SUMMARY We report an upper lip PA(benign mixed tumor)in a 28-year-old man.His complaint was a painless swelling on the upper lip.A painless,non-tender,well-circumscribed,slightly mobile,sessile,nodular,and rubbery(in consistency)tumor measuring 5.0 cm x 2.0 cm was noted on the left side of his upper lip.The overlying skin was not fixed and of normal color.There was no ulceration,and palpation did not elicit pain or bleeding.There was no history of trauma.Blunt dissection was used to completely excise the nodular,whitish,and encapsulated tumor.Microscopy showed a well-circumscribed and partly encapsulated biphasic lesion,with large lobules of myxo-chondroid stroma and intervening cellular nodules of basaloid cells,well-formed tubules containing eosinic secretion,and nests of myoepithelial cells.A diagnosis of PA(benign mixed tumor)was confirmed.CONCLUSION Blunt dissection is indicated to preserve the cosmesis and function of the upper lip.展开更多
In the nondestructive testing and evaluation area,magnetic major hysteresis loop measurement technology are widely applied for ferromagnetic material evaluation.However the characterization ability of major hysteresis...In the nondestructive testing and evaluation area,magnetic major hysteresis loop measurement technology are widely applied for ferromagnetic material evaluation.However the characterization ability of major hysteresis loop measurement technology greatly varies as the evaluated target properties.To solve this limitation,magnetic minor hysteresis loops,which reflect the responses of ferromagnetic material magnetization in a systematic way,is recommend.Inspired by plenty of information carried by the minor loops,the sensitivity mapping technique was developed to achieve the highest sensitivity of minor-loop parameters to the nondestructively evaluated targets.In this study,for the first time,the sensitivity mapping technique is used to measure the tensile force in a steel strand and evaluate the effective case depth in induction-hardened steel rods.The method and procedures for the sensitivity mapping technique are given before experimental detection.The obtained experimental results indicate that the linear correlation between the induced voltage(or the magnetic induction intensity)and the tensile force(or effective case depth)exists at most of the locations in the cluster of minor loops.The obtained sensitivity maps can be used to optimize the applied magnetic field(or excitation current)and the analyzed locations at the minor loops for achieving the highest sensitivity.For the purpose of tensile force measurement,it is suggested that the strand should be firstly magnetized to the near-saturation state and then restored to the remanent state.In this way,the highest sensitivity is obtained as about 15.26 mV/kN.As for the induction-hardened steel rods,the highest sensitivity of magnetic induction intensity to the effective case depth occurs under low magnetic field conditions and the absolute value of the highest sensitivity is about 0.1110 T/mm.This indicates that if the highest sensitivity is required in the case depth evaluation,the induction-hardened steel rods are only required to be weakly magnetized.The proposed sensitivity mapping technique shows the good performance in the high-sensitivity evaluation of tensile force and case depth in ferromagnetic materials and its application scope can be extended to other nondestructive detection fields.展开更多
BACKGROUND Severe refractory anemia during pregnancy can cause serious maternal and fetal complications.If the cause cannot be identified in time and accurately,blind symptomatic support treatment may cause serious ec...BACKGROUND Severe refractory anemia during pregnancy can cause serious maternal and fetal complications.If the cause cannot be identified in time and accurately,blind symptomatic support treatment may cause serious economic burden.Thalassemia minor pregnancy is commonly considered uneventful,and the condition of anemia rarely progresses during pregnancy.Autoimmune hemolytic anemia(AIHA)is rare during pregnancy with no exact incidence available.CASE SUMMARY We report the case of a 30-year-oldβ-thalassemia minor multiparous patient experiencing severe refractory anemia throughout pregnancy.We monitored the patient closely,carried out a full differential diagnosis,made a diagnosis of direct antiglobulin test-negative AIHA,and treated her with prednisone and intravenous immunoglobulin.The patient gave birth to a healthy full-term baby.CONCLUSION Coombs-negative AIHA should be suspected in cases of severe hemolytic anemia in pregnant patients with and without other hematological diseases.展开更多
BACKGROUND Primary Sjogren's syndrome(pSS)is an autoimmune disease,and renal involvement has been considered to be one of the systemic complications of pSS.Patients who have sjogren's syndrome with renal disea...BACKGROUND Primary Sjogren's syndrome(pSS)is an autoimmune disease,and renal involvement has been considered to be one of the systemic complications of pSS.Patients who have sjogren's syndrome with renal disease as the first manifestation and no exocrine gland involvement or autoantibodies can be missed clinically.CASE SUMMARY We here in report an unusual case of a primary Sjogren's syndrome in a 43-yearold female who had minimal lesion nephropathy as the initial presentation,and the patient was negative for serum anti-SSA and anti-SSB antibodies and did not have signs of exocrine gland involvement.The patient’s Sjogren's syndrome was confirmed by a minor salivary gland biopsy(MSGB)and a filter paper test.the patient’s oedema subsided,and the patient’s urinary protein resolved,showing that the treatment was effective.CONCLUSION MSGB should be considered if pSS is suspected in patients who do not have the typical pSS symptoms or who are positive for the specific autoantibodies.展开更多
文摘BACKGROUND Salivary gland tumors are relatively rare.Most minor salivary gland tumors are malignant with benign tumors accounting for 18%of the tumors.Pleomorphic adenoma(PA)is the most common salivary gland tumor.Lip PA is uncommon with 9.8%occurring in the upper lip.We are adding on the knowledge of the rare upper lip PA(benign mixed tumor).CASE SUMMARY We report an upper lip PA(benign mixed tumor)in a 28-year-old man.His complaint was a painless swelling on the upper lip.A painless,non-tender,well-circumscribed,slightly mobile,sessile,nodular,and rubbery(in consistency)tumor measuring 5.0 cm x 2.0 cm was noted on the left side of his upper lip.The overlying skin was not fixed and of normal color.There was no ulceration,and palpation did not elicit pain or bleeding.There was no history of trauma.Blunt dissection was used to completely excise the nodular,whitish,and encapsulated tumor.Microscopy showed a well-circumscribed and partly encapsulated biphasic lesion,with large lobules of myxo-chondroid stroma and intervening cellular nodules of basaloid cells,well-formed tubules containing eosinic secretion,and nests of myoepithelial cells.A diagnosis of PA(benign mixed tumor)was confirmed.CONCLUSION Blunt dissection is indicated to preserve the cosmesis and function of the upper lip.
基金Supported by National Key R&D Program of China(Grant No.2018YFF01012300)National Natural Science Foundation of China(Grant No.11527801).
文摘In the nondestructive testing and evaluation area,magnetic major hysteresis loop measurement technology are widely applied for ferromagnetic material evaluation.However the characterization ability of major hysteresis loop measurement technology greatly varies as the evaluated target properties.To solve this limitation,magnetic minor hysteresis loops,which reflect the responses of ferromagnetic material magnetization in a systematic way,is recommend.Inspired by plenty of information carried by the minor loops,the sensitivity mapping technique was developed to achieve the highest sensitivity of minor-loop parameters to the nondestructively evaluated targets.In this study,for the first time,the sensitivity mapping technique is used to measure the tensile force in a steel strand and evaluate the effective case depth in induction-hardened steel rods.The method and procedures for the sensitivity mapping technique are given before experimental detection.The obtained experimental results indicate that the linear correlation between the induced voltage(or the magnetic induction intensity)and the tensile force(or effective case depth)exists at most of the locations in the cluster of minor loops.The obtained sensitivity maps can be used to optimize the applied magnetic field(or excitation current)and the analyzed locations at the minor loops for achieving the highest sensitivity.For the purpose of tensile force measurement,it is suggested that the strand should be firstly magnetized to the near-saturation state and then restored to the remanent state.In this way,the highest sensitivity is obtained as about 15.26 mV/kN.As for the induction-hardened steel rods,the highest sensitivity of magnetic induction intensity to the effective case depth occurs under low magnetic field conditions and the absolute value of the highest sensitivity is about 0.1110 T/mm.This indicates that if the highest sensitivity is required in the case depth evaluation,the induction-hardened steel rods are only required to be weakly magnetized.The proposed sensitivity mapping technique shows the good performance in the high-sensitivity evaluation of tensile force and case depth in ferromagnetic materials and its application scope can be extended to other nondestructive detection fields.
文摘BACKGROUND Severe refractory anemia during pregnancy can cause serious maternal and fetal complications.If the cause cannot be identified in time and accurately,blind symptomatic support treatment may cause serious economic burden.Thalassemia minor pregnancy is commonly considered uneventful,and the condition of anemia rarely progresses during pregnancy.Autoimmune hemolytic anemia(AIHA)is rare during pregnancy with no exact incidence available.CASE SUMMARY We report the case of a 30-year-oldβ-thalassemia minor multiparous patient experiencing severe refractory anemia throughout pregnancy.We monitored the patient closely,carried out a full differential diagnosis,made a diagnosis of direct antiglobulin test-negative AIHA,and treated her with prednisone and intravenous immunoglobulin.The patient gave birth to a healthy full-term baby.CONCLUSION Coombs-negative AIHA should be suspected in cases of severe hemolytic anemia in pregnant patients with and without other hematological diseases.
文摘BACKGROUND Primary Sjogren's syndrome(pSS)is an autoimmune disease,and renal involvement has been considered to be one of the systemic complications of pSS.Patients who have sjogren's syndrome with renal disease as the first manifestation and no exocrine gland involvement or autoantibodies can be missed clinically.CASE SUMMARY We here in report an unusual case of a primary Sjogren's syndrome in a 43-yearold female who had minimal lesion nephropathy as the initial presentation,and the patient was negative for serum anti-SSA and anti-SSB antibodies and did not have signs of exocrine gland involvement.The patient’s Sjogren's syndrome was confirmed by a minor salivary gland biopsy(MSGB)and a filter paper test.the patient’s oedema subsided,and the patient’s urinary protein resolved,showing that the treatment was effective.CONCLUSION MSGB should be considered if pSS is suspected in patients who do not have the typical pSS symptoms or who are positive for the specific autoantibodies.
