Complexes of the type [Pt? (CH3NH2)(NH3){(OOC)2(CH2)n}] (Ⅰ～Ⅲ )(n=0,1,2) have been synthesized for the first time. At the same time, the three precursor complexes also have been synthesized. They were characterized ...Complexes of the type [Pt? (CH3NH2)(NH3){(OOC)2(CH2)n}] (Ⅰ～Ⅲ )(n=0,1,2) have been synthesized for the first time. At the same time, the three precursor complexes also have been synthesized. They were characterized by elemental analyses, molar conductance, differential thermal analyses and spectral (IR, UV, 1H NMR) studies. In vitro antitumor activity results indicated that these complexes have activity against HL 60 and U937, but show poor activity against K562.展开更多
文摘Complexes of the type [Pt? (CH3NH2)(NH3){(OOC)2(CH2)n}] (Ⅰ～Ⅲ )(n=0,1,2) have been synthesized for the first time. At the same time, the three precursor complexes also have been synthesized. They were characterized by elemental analyses, molar conductance, differential thermal analyses and spectral (IR, UV, 1H NMR) studies. In vitro antitumor activity results indicated that these complexes have activity against HL 60 and U937, but show poor activity against K562.
