Scientific and technical progress has been the driving forces of enterprises development.Milk productive enterprises are developing faster and growing better.It is very important to measure the contributive ratio of s...Scientific and technical progress has been the driving forces of enterprises development.Milk productive enterprises are developing faster and growing better.It is very important to measure the contributive ratio of scientific and technical progress in milk productive enterprises.And the appraisement could help to develop milk productive enterprises.The model C^2GS^2 was established to appraise the contributive ratio of scientific and technical progress in milk productive enterprises in the research.And the appraisement on the contributive ratio of scientific and technical progress in milk productive enterprises was made by the model.In the results of appraisement,science and technology play a main role in milk productive enterprises.It is shown that our milk productive enterprises are developed by scientific and technical progress while not by input of productive factors.展开更多
Shrimp(Penaeus vannamei)proteins have been shown an allergenic potential;however,little information is available on the sensitizing and eliciting capacity of shrimp protein digestion products.In this study,a BALB/c mi...Shrimp(Penaeus vannamei)proteins have been shown an allergenic potential;however,little information is available on the sensitizing and eliciting capacity of shrimp protein digestion products.In this study,a BALB/c mice model was used to explore the allergenicity of shrimp protein sample(SPS)and their gastric and gastrointestinal digestion products(GDS/GIDS).As compared with the SPS groups,the GDS/GIDS groups caused lower specific immunoglobulins(Ig E/Ig G1)levels(P<0.05),but higher than the control groups,indicating that the digestion products sensitized the mice.Meanwhile,spleen index,mouse mast cell protease-1(m MCP-1)concentration and proportion of degranulated mast cells were significantly reduced in the GDS/GIDS groups(P<0.05);simultaneously,allergic symptoms,vascular permeability and histopathological changes of tissues were alleviated.Nevertheless,the allergenicity of digestion products cannot be eliminated and still cause systemic allergic reactions in mice.The study showed that the digestion products of shrimp still had high sensitizing and eliciting capacity.展开更多
Based on the ablation micro-morphological characteristics, thermo-chemical ablation mechanism, and mechanical stripping mechanism, a dual-region solid rocket motor C/C throat liner ablation model and physical model ar...Based on the ablation micro-morphological characteristics, thermo-chemical ablation mechanism, and mechanical stripping mechanism, a dual-region solid rocket motor C/C throat liner ablation model and physical model are established. The ablation program was written and the experimental data of 70 lb BATES engine platform was used for model validation. The relative errors between the simulation calculation results and the experimental results were −6.83% - 10.20%. The ablation program was applied to study the effects of combustion chamber temperature, pressure, oxidation component concentration, throat particle concentration and particle scouring angle on the nozzle throat liner, which provides a reference for the design of the nozzle throat liner and the estimation of solid rocket motor ablation.展开更多
目的探讨血清肌酐胱抑素C比值(creatinine-cystatin C ratio,CCR)对鼻咽癌(nasopharyngeal carcinoma,NPC)的预后价值。方法回顾性分析2007年1月~2015年12月于陆军第七十二集团军医院进行诊治的NPC患者,根据CCR是否<0.81(中位数)分...目的探讨血清肌酐胱抑素C比值(creatinine-cystatin C ratio,CCR)对鼻咽癌(nasopharyngeal carcinoma,NPC)的预后价值。方法回顾性分析2007年1月~2015年12月于陆军第七十二集团军医院进行诊治的NPC患者,根据CCR是否<0.81(中位数)分为高表达组和低表达组,对高表达组和低表达组的预测变量进行比较。采用Kaplan-Meier生存分析法及Cox回归分析CCR对总生存期(overall survival,OS)的影响,基于相关预测因素构建临床预测模型及列线图并对其进行评价。结果共纳入516例NPC患者,高表达组中高龄患者占比(22.5%)明显低于低表达组(32.6%),高分化患者占比(22.5%)明显更高(14.7%),TNM分期为Ⅰ期和Ⅱ期的患者占比(40.7%)明显高于低表达组(29.8%),上述指标差异均有统计学意义(P均<0.05)。Kaplan-Meier生存分析提示低表达的CCR与较差的OS显著相关,多因素Cox回归分析结果表明,年龄、CCR、病理学分级、从确诊到治疗时间、TNM分期与OS显著相关(P<0.05)。基于上述预测因素构建的临床预测模型的AUC值高于传统TNM分期模型,且其列线图预测OS时与实际有较好的一致性。结论CCR可被视为NPC患者的一个潜在的预后评估因素。展开更多
基金Supported by Fund of Post Doctoral Research in Heilongjiang Province(LSZH-04052)Fund of Scientific and Technical Research Projects(10551039)
文摘Scientific and technical progress has been the driving forces of enterprises development.Milk productive enterprises are developing faster and growing better.It is very important to measure the contributive ratio of scientific and technical progress in milk productive enterprises.And the appraisement could help to develop milk productive enterprises.The model C^2GS^2 was established to appraise the contributive ratio of scientific and technical progress in milk productive enterprises in the research.And the appraisement on the contributive ratio of scientific and technical progress in milk productive enterprises was made by the model.In the results of appraisement,science and technology play a main role in milk productive enterprises.It is shown that our milk productive enterprises are developed by scientific and technical progress while not by input of productive factors.
基金financially supported by the National Natural Science Foundation of China(32022067)the Dalian Sci-Tech Talent Innovation Support Program(2022RY04)。
文摘Shrimp(Penaeus vannamei)proteins have been shown an allergenic potential;however,little information is available on the sensitizing and eliciting capacity of shrimp protein digestion products.In this study,a BALB/c mice model was used to explore the allergenicity of shrimp protein sample(SPS)and their gastric and gastrointestinal digestion products(GDS/GIDS).As compared with the SPS groups,the GDS/GIDS groups caused lower specific immunoglobulins(Ig E/Ig G1)levels(P<0.05),but higher than the control groups,indicating that the digestion products sensitized the mice.Meanwhile,spleen index,mouse mast cell protease-1(m MCP-1)concentration and proportion of degranulated mast cells were significantly reduced in the GDS/GIDS groups(P<0.05);simultaneously,allergic symptoms,vascular permeability and histopathological changes of tissues were alleviated.Nevertheless,the allergenicity of digestion products cannot be eliminated and still cause systemic allergic reactions in mice.The study showed that the digestion products of shrimp still had high sensitizing and eliciting capacity.
文摘Based on the ablation micro-morphological characteristics, thermo-chemical ablation mechanism, and mechanical stripping mechanism, a dual-region solid rocket motor C/C throat liner ablation model and physical model are established. The ablation program was written and the experimental data of 70 lb BATES engine platform was used for model validation. The relative errors between the simulation calculation results and the experimental results were −6.83% - 10.20%. The ablation program was applied to study the effects of combustion chamber temperature, pressure, oxidation component concentration, throat particle concentration and particle scouring angle on the nozzle throat liner, which provides a reference for the design of the nozzle throat liner and the estimation of solid rocket motor ablation.
文摘目的探讨血清肌酐胱抑素C比值(creatinine-cystatin C ratio,CCR)对鼻咽癌(nasopharyngeal carcinoma,NPC)的预后价值。方法回顾性分析2007年1月~2015年12月于陆军第七十二集团军医院进行诊治的NPC患者,根据CCR是否<0.81(中位数)分为高表达组和低表达组,对高表达组和低表达组的预测变量进行比较。采用Kaplan-Meier生存分析法及Cox回归分析CCR对总生存期(overall survival,OS)的影响,基于相关预测因素构建临床预测模型及列线图并对其进行评价。结果共纳入516例NPC患者,高表达组中高龄患者占比(22.5%)明显低于低表达组(32.6%),高分化患者占比(22.5%)明显更高(14.7%),TNM分期为Ⅰ期和Ⅱ期的患者占比(40.7%)明显高于低表达组(29.8%),上述指标差异均有统计学意义(P均<0.05)。Kaplan-Meier生存分析提示低表达的CCR与较差的OS显著相关,多因素Cox回归分析结果表明,年龄、CCR、病理学分级、从确诊到治疗时间、TNM分期与OS显著相关(P<0.05)。基于上述预测因素构建的临床预测模型的AUC值高于传统TNM分期模型,且其列线图预测OS时与实际有较好的一致性。结论CCR可被视为NPC患者的一个潜在的预后评估因素。
