Background:As the market demands change,SMEs(small and medium-sized enterprises)have long faced many design issues,including high costs,lengthy cycles,and insufficient innovation.These issues are especially noticeable...Background:As the market demands change,SMEs(small and medium-sized enterprises)have long faced many design issues,including high costs,lengthy cycles,and insufficient innovation.These issues are especially noticeable in the domain of cosmetic packaging design.Objective:To explore innovative product family modeling methods and configuration design processes to improve the efficiency of enterprise cosmetic packaging design and develop the design for mass customization.Methods:To accomplish this objective,the basic-element theory has been introduced and applied to the design and development system of the product family.Results:By examining the mapping relationships between the demand domain,functional domain,technology domain,and structure domain,four interrelated models have been developed,including the demand model,functional model,technology model,and structure model.Together,these models form the mechanism and methodology of product family modeling,specifically for cosmetic packaging design.Through an analysis of a case study on men’s cosmetic packaging design,the feasibility of the proposed product family modeling technology has been demonstrated in terms of customized cosmetic packaging design,and the design efficiency has been enhanced.Conclusion:The product family modeling technology employs a formalized element as a module configuration design language,permeating throughout the entire development cycle of cosmetic packaging design,thus facilitating a structured and modularized configuration design process for the product family system.The application of the basic-element principle in product family modeling technology contributes to the enrichment of the research field surrounding cosmetic packaging product family configuration design,while also providing valuable methods and references for enterprises aiming to elevate the efficiency of cosmetic packaging design for the mass customization product model.展开更多
Objective: To study the application effect of the family collaborative care model on elderly patients with type 2 diabetes mellitus and its influence on self-care ability. Methods: The elderly type 2 diabetes mellitus...Objective: To study the application effect of the family collaborative care model on elderly patients with type 2 diabetes mellitus and its influence on self-care ability. Methods: The elderly type 2 diabetes mellitus patients (400 cases) treated in our hospital between March 2020 and July 2023 were divided into two groups by randomized grouping method;the control group received the conventional nursing program, while the observation group received the family collaborative nursing model. Blood glucose level, self-care ability, and quality of life were compared between the groups. Results: The blood glucose level of the observation group was lower than that of the control group (P < 0.05). The self- care ability and quality of life scores of the observation group were higher than those of the control group (P < 0.05). Conclusion: The family collaborative care model for elderly patients with type 2 diabetes mellitus can promote their self- care ability, improve the effect of glycemic control, and improve their quality of life, and is suitable for further promotion and application.展开更多
This paper selects the daily data of national oil prices from January 2, 2014 to February 28, 2019, establishes an ARMA (2, 0) model, and tests its residuals for ARCH effects. Finally, the TARCH (1, 1) model is determ...This paper selects the daily data of national oil prices from January 2, 2014 to February 28, 2019, establishes an ARMA (2, 0) model, and tests its residuals for ARCH effects. Finally, the TARCH (1, 1) model is determined to quantitatively analyze the volatility of the crude oil market.展开更多
A suitable statistical model has been explored for the investors as well as the researchers to resolve the future estimation of share volume by using daily stock volume data from Dhaka Stock Exchange (DSE). The dail...A suitable statistical model has been explored for the investors as well as the researchers to resolve the future estimation of share volume by using daily stock volume data from Dhaka Stock Exchange (DSE). The daily volume data from the June 1, 2004 to April 19, 2010 were retrieved from DSE website as a secondary data source. The Maximum Likelihood---Autoregressive Conditional Heteroskedasticity (ARCH) (Marquardt) method has been applied to construct the models for the stock volume data of DSE by using statistical package software E-Views of verson-5. First of all, an "Auto Regressive Integrated Moving Average (ARIMA) model" was fitted and observed that heteroscedastic volatilities were still present there. To eliminate this dilemma, ARCH class of volatility models has been used and finally the ARIMA with EGARCH model has been explored. Findings of this study have recognized that ARIMA with EGARCH model implies low mean square error, low mean absolute error, low bias proportion, and low variance proportion for share volume data with comparing to other models. Hence, the modelling concept established in this study would be a decisive study for the investors as well as the researchers.展开更多
In order to overcome defects of the classical hidden Markov model (HMM), Markov family model (MFM), a new statistical model was proposed. Markov family model was applied to speech recognition and natural language proc...In order to overcome defects of the classical hidden Markov model (HMM), Markov family model (MFM), a new statistical model was proposed. Markov family model was applied to speech recognition and natural language processing. The speaker independently continuous speech recognition experiments and the part-of-speech tagging experiments show that Markov family model has higher performance than hidden Markov model. The precision is enhanced from 94.642% to 96.214% in the part-of-speech tagging experiments, and the work rate is reduced by 11.9% in the speech recognition experiments with respect to HMM baseline system.展开更多
In this paper, exponential type regression models are considered from geometric point of view. The stochastic expansions relating to the estimate are derived and are used to study several asymptotic inference problems...In this paper, exponential type regression models are considered from geometric point of view. The stochastic expansions relating to the estimate are derived and are used to study several asymptotic inference problems. The biases and the covariances relating to the estimate may be calculated based on the expansions. The information loss of the estimate and a limit theorem connected with the observed and expected Fisher informations are obtained in terms of the curvatures.展开更多
By using GARCH(1,1)-M and EGARCH(1,1)-M models, the relationships among funds speculation transaction, arbitrage transaction and the fluctuation of international copper future price were studied. The news impact c...By using GARCH(1,1)-M and EGARCH(1,1)-M models, the relationships among funds speculation transaction, arbitrage transaction and the fluctuation of international copper future price were studied. The news impact curve of copper future price fluctuation respectively introduced funds speculation position and arbitrage position was given, and the result is consistent with the empirical study conclusion. The results show that investment funds are not the factor that causes copper future price fluctuation, but can reduce the copper future price fluctuation; the copper future price fluctuation is more sensitive to negative information, and ftmd speculative positions can reduce asymmetric effect of copper price fluctuation, while fimds arbitrage position influences less.展开更多
Decompression is the major therapeutic strategy for acute spinal cord injury,but there is some debate about the time window for decompression following spinal cord injury.An important goal and challenge in the treatme...Decompression is the major therapeutic strategy for acute spinal cord injury,but there is some debate about the time window for decompression following spinal cord injury.An important goal and challenge in the treatment of spinal cord injury is inhibiting or reversing secondary injury.Governor Vessel electroacupuncture can improve symptoms of spinal cord injury by inhibiting cell apoptosis and improving the microenvironment of the injured spinal cord.In this study,Governor Vessel electroacupuncture combined with decompression at different time points was used to treat acute spinal cord injury.The rat models were established by inserting a balloon catheter into the atlanto-occipital space.The upper cervical spinal cord was compressed for 12 or 48 hours prior to decompression.Electroacupuncture was conducted at the acupoints Dazhui(GV14) and Baihui(GV 20)(2 Hz,15 minutes) once a day for 14 consecutive days.Compared with decompression alone,hind limb motor function recovery was superior after decompression for 12 and 48 hours combined with electroacupuncture.However,the recovery of motor function was not significantly different at 14 days after treatment in rats receiving decompression for 12 hours.Platelet-activating factor levels and caspase-9 protein expression were significantly reduced in rats receiving electroacupuncture compared with decompression alone.These findings indicate that compared with decompression alone,Governor Vessel electroacupuncture combined with delayed decompression(48 hours) is more effective in the treatment of upper cervical spinal cord injury.Governor Vessel electroacupuncture combined with early decompression(12 hours) can accelerate the recovery of nerve movement in rats with upper cervical spinal cord injury.Nevertheless,further studies are necessary to confirm whether it is possible to obtain additional benefit compared with early decompression alone.展开更多
Using the form factors calculated in the three-point QCD sum rules, we calculate the new physics contri- butions to the physical observables of Bc→D;μ+ μ- decay in a family non-universal Z' model. Under the consi...Using the form factors calculated in the three-point QCD sum rules, we calculate the new physics contri- butions to the physical observables of Bc→D;μ+ μ- decay in a family non-universal Z' model. Under the consideration of three cases of the new physics parameters, we find that: (a) the Z' boson can provide large contributions to the differential decay rates; (b) the forward-backward asymmetry (FBA) can be increased by about 47%, 38%, and 110% at most in S1, S2, and extreme limR values (ELV), respectively. In addition, the zero crossing can be shifted in all the cases; (c) when s 〉 0.08, the value Of PL can be changed from -1 in the Standard Model (SM) to -0.5 in S1, -0.6 in S2, and 0 in extreme limit values, respectively; (d) the new physics corrections to PT will decrease the SM prediction about 25% for the cases of S1 and S2, 100% for the case of ELV.展开更多
This paper examined variation in Onko dialect using the family tree model and the corresponding comparative method as the theoretical tool. A wordlist of basic items and a designed frame technique were used to gather ...This paper examined variation in Onko dialect using the family tree model and the corresponding comparative method as the theoretical tool. A wordlist of basic items and a designed frame technique were used to gather data for this study. The data were presented in tables and the analyses were done through descriptive statistics. The data were analyzed to determine variation at the phonological, syntactic and lexical levels. The study revealed differences between Standard Yoruba and Onko dialect as well as the variation therein. Two basic factors discovered to be responsible for variations in Onko are geography(distribution of Onko communities) and language contact. The paper established that Onko exhibits variations, which are however not significant enough to disrupt mutual intelligibility among the speakers, and thus all the varieties remain a single dialect.展开更多
The presenilin genes(PSEN1 and PSEN2)are mainly responsible for causing early-onset familial Alzheimer’s disease,harboring~300 causative mutations,and representing~90%of all mutations associated with a very aggressiv...The presenilin genes(PSEN1 and PSEN2)are mainly responsible for causing early-onset familial Alzheimer’s disease,harboring~300 causative mutations,and representing~90%of all mutations associated with a very aggressive disease form.Presenilin 1 is the catalytic core of theγ-secretase complex that conducts the intramembranous proteolytic excision of multiple transmembrane proteins like the amyloid precursor protein,Notch-1,N-and E-cadherin,LRP,Syndecan,Delta,Jagged,CD44,ErbB4,and Nectin1a.Presenilin 1 plays an essential role in neural progenitor maintenance,neurogenesis,neurite outgrowth,synaptic function,neuronal function,myelination,and plasticity.Therefore,an imbalance caused by mutations in presenilin 1/γ-secretase might cause aberrant signaling,synaptic dysfunction,memory impairment,and increased Aβ42/Aβ40 ratio,contributing to neurodegeneration during the initial stages of Alzheimer’s disease pathogenesis.This review focuses on the neuronal differentiation dysregulation mediated by PSEN1 mutations in Alzheimer’s disease.Furthermore,we emphasize the importance of Alzheimer’s disease-induced pluripotent stem cells models in analyzing PSEN1 mutations implication over the early stages of the Alzheimer’s disease pathogenesis throughout neuronal differentiation impairment.展开更多
基金the Guangdong Planning Office of Philosophy and Social Science(Grant No.GD22XYS04).
文摘Background:As the market demands change,SMEs(small and medium-sized enterprises)have long faced many design issues,including high costs,lengthy cycles,and insufficient innovation.These issues are especially noticeable in the domain of cosmetic packaging design.Objective:To explore innovative product family modeling methods and configuration design processes to improve the efficiency of enterprise cosmetic packaging design and develop the design for mass customization.Methods:To accomplish this objective,the basic-element theory has been introduced and applied to the design and development system of the product family.Results:By examining the mapping relationships between the demand domain,functional domain,technology domain,and structure domain,four interrelated models have been developed,including the demand model,functional model,technology model,and structure model.Together,these models form the mechanism and methodology of product family modeling,specifically for cosmetic packaging design.Through an analysis of a case study on men’s cosmetic packaging design,the feasibility of the proposed product family modeling technology has been demonstrated in terms of customized cosmetic packaging design,and the design efficiency has been enhanced.Conclusion:The product family modeling technology employs a formalized element as a module configuration design language,permeating throughout the entire development cycle of cosmetic packaging design,thus facilitating a structured and modularized configuration design process for the product family system.The application of the basic-element principle in product family modeling technology contributes to the enrichment of the research field surrounding cosmetic packaging product family configuration design,while also providing valuable methods and references for enterprises aiming to elevate the efficiency of cosmetic packaging design for the mass customization product model.
文摘Objective: To study the application effect of the family collaborative care model on elderly patients with type 2 diabetes mellitus and its influence on self-care ability. Methods: The elderly type 2 diabetes mellitus patients (400 cases) treated in our hospital between March 2020 and July 2023 were divided into two groups by randomized grouping method;the control group received the conventional nursing program, while the observation group received the family collaborative nursing model. Blood glucose level, self-care ability, and quality of life were compared between the groups. Results: The blood glucose level of the observation group was lower than that of the control group (P < 0.05). The self- care ability and quality of life scores of the observation group were higher than those of the control group (P < 0.05). Conclusion: The family collaborative care model for elderly patients with type 2 diabetes mellitus can promote their self- care ability, improve the effect of glycemic control, and improve their quality of life, and is suitable for further promotion and application.
文摘This paper selects the daily data of national oil prices from January 2, 2014 to February 28, 2019, establishes an ARMA (2, 0) model, and tests its residuals for ARCH effects. Finally, the TARCH (1, 1) model is determined to quantitatively analyze the volatility of the crude oil market.
文摘A suitable statistical model has been explored for the investors as well as the researchers to resolve the future estimation of share volume by using daily stock volume data from Dhaka Stock Exchange (DSE). The daily volume data from the June 1, 2004 to April 19, 2010 were retrieved from DSE website as a secondary data source. The Maximum Likelihood---Autoregressive Conditional Heteroskedasticity (ARCH) (Marquardt) method has been applied to construct the models for the stock volume data of DSE by using statistical package software E-Views of verson-5. First of all, an "Auto Regressive Integrated Moving Average (ARIMA) model" was fitted and observed that heteroscedastic volatilities were still present there. To eliminate this dilemma, ARCH class of volatility models has been used and finally the ARIMA with EGARCH model has been explored. Findings of this study have recognized that ARIMA with EGARCH model implies low mean square error, low mean absolute error, low bias proportion, and low variance proportion for share volume data with comparing to other models. Hence, the modelling concept established in this study would be a decisive study for the investors as well as the researchers.
基金Project(60763001)supported by the National Natural Science Foundation of ChinaProjects(2009GZS0027,2010GZS0072)supported by the Natural Science Foundation of Jiangxi Province,China
文摘In order to overcome defects of the classical hidden Markov model (HMM), Markov family model (MFM), a new statistical model was proposed. Markov family model was applied to speech recognition and natural language processing. The speaker independently continuous speech recognition experiments and the part-of-speech tagging experiments show that Markov family model has higher performance than hidden Markov model. The precision is enhanced from 94.642% to 96.214% in the part-of-speech tagging experiments, and the work rate is reduced by 11.9% in the speech recognition experiments with respect to HMM baseline system.
基金The project was supported by National Natural Science Foundation of China
文摘In this paper, exponential type regression models are considered from geometric point of view. The stochastic expansions relating to the estimate are derived and are used to study several asymptotic inference problems. The biases and the covariances relating to the estimate may be calculated based on the expansions. The information loss of the estimate and a limit theorem connected with the observed and expected Fisher informations are obtained in terms of the curvatures.
基金Project(20090162120086) supported by Research Fund for the Doctoral Program of Higher Education of ChinaProject(10YJCZH123) supported by Humanity and Social Science Foundation of Ministry of Education of China+2 种基金Project(12JJ4077) supported by the National Natural Science Foundation of Hunan Province of ChinaProject(2009ZK3053) supported by Soft Science Research Project of Hunan Province of ChinaProject supported by the Freedom Explore Program of Central South University,China
文摘By using GARCH(1,1)-M and EGARCH(1,1)-M models, the relationships among funds speculation transaction, arbitrage transaction and the fluctuation of international copper future price were studied. The news impact curve of copper future price fluctuation respectively introduced funds speculation position and arbitrage position was given, and the result is consistent with the empirical study conclusion. The results show that investment funds are not the factor that causes copper future price fluctuation, but can reduce the copper future price fluctuation; the copper future price fluctuation is more sensitive to negative information, and ftmd speculative positions can reduce asymmetric effect of copper price fluctuation, while fimds arbitrage position influences less.
基金supported by the Capital Characteristic Clinical Application Research Projects of Beijing Municipal Science and Technology Plan of China,No.Z16110000516009
文摘Decompression is the major therapeutic strategy for acute spinal cord injury,but there is some debate about the time window for decompression following spinal cord injury.An important goal and challenge in the treatment of spinal cord injury is inhibiting or reversing secondary injury.Governor Vessel electroacupuncture can improve symptoms of spinal cord injury by inhibiting cell apoptosis and improving the microenvironment of the injured spinal cord.In this study,Governor Vessel electroacupuncture combined with decompression at different time points was used to treat acute spinal cord injury.The rat models were established by inserting a balloon catheter into the atlanto-occipital space.The upper cervical spinal cord was compressed for 12 or 48 hours prior to decompression.Electroacupuncture was conducted at the acupoints Dazhui(GV14) and Baihui(GV 20)(2 Hz,15 minutes) once a day for 14 consecutive days.Compared with decompression alone,hind limb motor function recovery was superior after decompression for 12 and 48 hours combined with electroacupuncture.However,the recovery of motor function was not significantly different at 14 days after treatment in rats receiving decompression for 12 hours.Platelet-activating factor levels and caspase-9 protein expression were significantly reduced in rats receiving electroacupuncture compared with decompression alone.These findings indicate that compared with decompression alone,Governor Vessel electroacupuncture combined with delayed decompression(48 hours) is more effective in the treatment of upper cervical spinal cord injury.Governor Vessel electroacupuncture combined with early decompression(12 hours) can accelerate the recovery of nerve movement in rats with upper cervical spinal cord injury.Nevertheless,further studies are necessary to confirm whether it is possible to obtain additional benefit compared with early decompression alone.
基金Supported by the National Natural Science Foundation of China under Grant Nos. 10947020 and 11147004Natural Science Foundation of Henan Province under Grant No. 112300410188
文摘Using the form factors calculated in the three-point QCD sum rules, we calculate the new physics contri- butions to the physical observables of Bc→D;μ+ μ- decay in a family non-universal Z' model. Under the consideration of three cases of the new physics parameters, we find that: (a) the Z' boson can provide large contributions to the differential decay rates; (b) the forward-backward asymmetry (FBA) can be increased by about 47%, 38%, and 110% at most in S1, S2, and extreme limR values (ELV), respectively. In addition, the zero crossing can be shifted in all the cases; (c) when s 〉 0.08, the value Of PL can be changed from -1 in the Standard Model (SM) to -0.5 in S1, -0.6 in S2, and 0 in extreme limit values, respectively; (d) the new physics corrections to PT will decrease the SM prediction about 25% for the cases of S1 and S2, 100% for the case of ELV.
文摘This paper examined variation in Onko dialect using the family tree model and the corresponding comparative method as the theoretical tool. A wordlist of basic items and a designed frame technique were used to gather data for this study. The data were presented in tables and the analyses were done through descriptive statistics. The data were analyzed to determine variation at the phonological, syntactic and lexical levels. The study revealed differences between Standard Yoruba and Onko dialect as well as the variation therein. Two basic factors discovered to be responsible for variations in Onko are geography(distribution of Onko communities) and language contact. The paper established that Onko exhibits variations, which are however not significant enough to disrupt mutual intelligibility among the speakers, and thus all the varieties remain a single dialect.
基金supported by the Consejo Nacional de Ciencia y Tecnología Scholarship 711893(to MAH)and 711874(to EER)。
文摘The presenilin genes(PSEN1 and PSEN2)are mainly responsible for causing early-onset familial Alzheimer’s disease,harboring~300 causative mutations,and representing~90%of all mutations associated with a very aggressive disease form.Presenilin 1 is the catalytic core of theγ-secretase complex that conducts the intramembranous proteolytic excision of multiple transmembrane proteins like the amyloid precursor protein,Notch-1,N-and E-cadherin,LRP,Syndecan,Delta,Jagged,CD44,ErbB4,and Nectin1a.Presenilin 1 plays an essential role in neural progenitor maintenance,neurogenesis,neurite outgrowth,synaptic function,neuronal function,myelination,and plasticity.Therefore,an imbalance caused by mutations in presenilin 1/γ-secretase might cause aberrant signaling,synaptic dysfunction,memory impairment,and increased Aβ42/Aβ40 ratio,contributing to neurodegeneration during the initial stages of Alzheimer’s disease pathogenesis.This review focuses on the neuronal differentiation dysregulation mediated by PSEN1 mutations in Alzheimer’s disease.Furthermore,we emphasize the importance of Alzheimer’s disease-induced pluripotent stem cells models in analyzing PSEN1 mutations implication over the early stages of the Alzheimer’s disease pathogenesis throughout neuronal differentiation impairment.