The subway is the primary travel tool for urban residents in China. Due to the complex structure of the subway and high personnel density in rush hours, subway evacuation capacity is critical. The subway evacuation mo...The subway is the primary travel tool for urban residents in China. Due to the complex structure of the subway and high personnel density in rush hours, subway evacuation capacity is critical. The subway evacuation model is explored in this work by combining the improved social force model with the view radius using the Vicsek model. The pedestrians are divided into two categories based on different force models. The first category is sensitive pedestrians who have normal responses to emergency signs. The second category is insensitive pedestrians. By simulating different proportions of the insensitive pedestrians, we find that the escape time is directly proportional to the number of insensitive pedestrians and inversely proportional to the view radius. However, when the view radius is large enough, the escape time does not change significantly, and the evacuation of people in a small view radius environment tends to be integrated. With the improvement of view radius conditions, the escape time changes more obviously with the proportion of insensitive pedestrians. A new emergency sign layout is proposed, and the simulations show that the proposed layout can effectively reduce the escape time in a small view radius environment. However, the evacuation effect of the new escape sign layout on the large view radius environment is not apparent. In this case, the exit setting emerges as an additional factor affecting the escape time.展开更多
In order to theoretically study the growth morphology of dihydroxylammonium 5,5’-bistetrazole-1,1’-dio late(TKX-50)crystal in different solvent systems,crystal–solvent models were established,and then molecular dyn...In order to theoretically study the growth morphology of dihydroxylammonium 5,5’-bistetrazole-1,1’-dio late(TKX-50)crystal in different solvent systems,crystal–solvent models were established,and then molecular dynamics(MD)methods were adopted as a means to simulate particle motion.Modified attachment energy(MAE)model was employed to calculate the growth morphology of TKX-50.The simulation results demonstrate that COMPASS force field and RESP charge are suitable for molecular dynamics simulation of TKX-50.The morphologically dominant growth surfaces of TKX-50 in vacuum are(020),(011),(11–1),(100)and(120),respectively.In water(H_(2)O)and N,N-dimethylformamide(DMF)solvents,the(11–1)face is the largest in the habit face,the growth rate of(020)face becomes faster.With the increase of temperature,the aspect ratios of TKX-50 crystal in DMF solvent increase,and the areas of the(120)faces decrease.In ethylene glycol/H_(2)O mixed solvent system with volume ratio of 1/1,aspect ratio of TKX-50 is relatively small.In formic acid/H_(2)O mixed solvents with different volume ratios(1/4,1/3,1/2,1/1 and 2/1),aspect ratio of TKX-50 is relatively small when volume ratio is 1/2.展开更多
Considering the compressibility of the cavity in the cavitating flow, this paper presents a modified k-ω model for predicting the cavitating flow in a centrifugal pump, in which the modified k-ω model and Schnerr-Sa...Considering the compressibility of the cavity in the cavitating flow, this paper presents a modified k-ω model for predicting the cavitating flow in a centrifugal pump, in which the modified k-ω model and Schnerr-Sauer cavitation model were combined with ANSYS CFX. To evaluate the modified and standard k-co models, numerical simulations were performed with these two models, respectively, and the calculation results were compared with the experimental data. Numerical simulations were executed with three different values of the flow coefficient, and the simulation results of the modified k-ω model showed agreement with most of the experimental data. The cavitating flow in the centrifugal pump obtained by the modified k-ω model at the design flow coefficient of 0.102, was analyzed. When the cavitation number decreases, the cavity initially generates on the suction side of the blade near the leading edge and then expands to the outlet of the impeller, and the decrease of the total pressure coefficient mainly occurs upstream of the impeller passage, while the downstream remains almost unaffected by the development of cavitation.展开更多
AIM:To explore the related risk factors for diabetic retinopathy(DR)in type 2 diabetes with insulin therapy.METHODS:We studied the relationships among blood glucose,serum C-peptide,plasma insulin,beta-cell function an...AIM:To explore the related risk factors for diabetic retinopathy(DR)in type 2 diabetes with insulin therapy.METHODS:We studied the relationships among blood glucose,serum C-peptide,plasma insulin,beta-cell function and the development of DR.Beta-cell function was assessed by a modified homeostasis model assessment(modified HOMA)which was gained by using C-peptide to replace insulin in the homeostasis model assessment(HOMA)of beta-cell function.We also studied the relationships between modified HOMA index and serum C-peptide response to 100 g tasteless steamed bread to determine the accuracy of modified HOMA.RESULTS:Our study group consisted of 170 type 2diabetic inpatients with DR(age:58.35±13.87y,mean±SD)and 205 type 2 diabetic inpatients with no DR(NDR)(age:65.52±11.59y).DR patients had higher age,longer diabetic duration,higher hypertension grade,higher postprandial plasma glucose,higher fluctuation level of plasma glucose,lower body mass index(BMI),lower postprandial serum insulin and C-peptide,lower fluctuation level of serum insulin and C-peptide(P【0.05).In our logistic regression model,duration of diabetes,hypertension grade,fasting plasma insulin and glycosylated hemoglobin(HbA1C)were significantly associated with the presence of DR after adjustment for confounding factors(P【0.05).CONCLUSION:Our results suggested although modified HOMA showed significant correlation to the occurrence of DR on Spearman’s rank-correlationanalysis,logistic regression showed no significant association between these two variables after adjustment for relevant confounding factors(such as age,sex,duration of diabetes,BMI,hypertension grade,HbA1C,plasma insulin).Duration of diabetes,hypertension grade,fasting plasma insulin and HbA1C were independently associated with the development of DR in Chinese type 2 diabetics.展开更多
Considering the discontinuous characteristics of sea ice on various scales,a modified discrete element model(DEM) for sea ice dynamics is developed based on the granular material rheology.In this modified DEM,a soft...Considering the discontinuous characteristics of sea ice on various scales,a modified discrete element model(DEM) for sea ice dynamics is developed based on the granular material rheology.In this modified DEM,a soft sea ice particle element is introduced as a self-adjustive particle size function.Each ice particle can be treated as an assembly of ice floes,with its concentration and thickness changing to variable sizes under the conservation of mass.In this model,the contact forces among ice particles are calculated using a viscous-elastic-plastic model,while the maximum shear forces are described with the Mohr-Coulomb friction law.With this modified DEM,the ice flow dynamics is simulated under the drags of wind and current in a channel of various widths.The thicknesses,concentrations and velocities of ice particles are obtained,and then reasonable dynamic process is analyzed.The sea ice dynamic process is also simulated in a vortex wind field.Taking the influence of thermodynamics into account,this modified DEM will be improved in the future work.展开更多
Two modifications for the basic Barcelona model(BBM) are present. One is the replacement of the net stress by the average skeleton stress in unsaturated soil modeling, and the other is the adoption of an expression fo...Two modifications for the basic Barcelona model(BBM) are present. One is the replacement of the net stress by the average skeleton stress in unsaturated soil modeling, and the other is the adoption of an expression for the load-collapse(LC) yield surface that can match flexibly the normal compression lines at different suctions. The predictions of the modified BBM for the controlled-suction triaxial test on the unsaturated compacted clay are presented and compared with the experimental results. A good agreement between the predicted and experimental results demonstrates the reasonability of the modified BBM. On this basis, the coupled processes of groundwater flow and soil deformation in a homogeneous soil slope under a long heavy rainfall are simulated with the proposed elasto-plastic model. The numerical results reveal that the failure of a slope under rainfall infiltration is due to both the reduction of soil suction and the significant rise in groundwater table. The evolution of the displacements is greatly related to the change of suction. The maximum collapse deformation happens near the surface of slope where infiltrated rainwater can quickly reach. The results may provide a helpful reference for hazard assessment and control of rainfall-induced landslides.展开更多
The modified sub regular solution model was used for a calculation of the activity coefficient of immiscible binary alloy systems. The parameters needed for the calculation are the interaction parameters, λ 1 a...The modified sub regular solution model was used for a calculation of the activity coefficient of immiscible binary alloy systems. The parameters needed for the calculation are the interaction parameters, λ 1 and λ 2, which are represented as a linear function of temperature, T . The molar excess Gibbs free energy, G m E, can be written in the form G m E= x A x B[( λ 11 + λ 12 T )+( λ 21 + λ 22 T ) x B ] The calculation is carried out numerically for three immiscible binary alloy systems, Al Pb, Cu Tl and In V. The agreement between the calculated and experimentally determined values of activity coefficient is excellent.展开更多
A modified Monte Carlo model of speckle tracking of shear wave propagation in scattering media is proposed. The established Monte Carlo model mainly concerns the variations of optical electric field and speckle. The t...A modified Monte Carlo model of speckle tracking of shear wave propagation in scattering media is proposed. The established Monte Carlo model mainly concerns the variations of optical electric field and speckle. The two- dimensional intensity distribution and the time evolution of speckles in different probe locations are obtained. The fluctuation of speckle intensity tracks the acoustic-radiation-force shear wave propagation, and especially the reduction of speckle intensity implies attenuation of shear wave. Then, the shear wave velocity is estimated quantitatively on the basis of the time-to-peak algorithm and linear regression processing. The results reveal that a smaller sampling interval yields higher estimation precision and the shear wave velocity is estimated more efficiently by using speckle intensity difference than by using speckle contrast difference according to the estimation error. Hence, the shear wave velocity is estimated to be 2.25 m/s with relatively high accuracy for the estimation error reaches the minimum (0.071).展开更多
A simple modified analytic EAM model for bcc Fe and fcc Al was used to calculate the lattice constant and elastic constants of B2 FeAl and DO3 Fe3Al alloys. The formation energies of vacancy and antisite were also cal...A simple modified analytic EAM model for bcc Fe and fcc Al was used to calculate the lattice constant and elastic constants of B2 FeAl and DO3 Fe3Al alloys. The formation energies of vacancy and antisite were also calculated. The present calculations are in agreement with the experimental data and the theoretical results obtained by other authors.展开更多
The dynamic compression experiments with Split-Hopkinson Pressure Bar(SHPB)were performed on AZ31 magnesium alloy rolled sheet specimens in the normal direction(AZ31-ND)with{0002}texture at the temperature of 293-523 ...The dynamic compression experiments with Split-Hopkinson Pressure Bar(SHPB)were performed on AZ31 magnesium alloy rolled sheet specimens in the normal direction(AZ31-ND)with{0002}texture at the temperature of 293-523 K and the strain rate of 0.001-2200 s^−1.The temperature term in Johnson-Cook(JC)constitutive model had been reasonably modified.This advantage made constitutive model promising for decribing the dynamic deformation behavior of AZ31-ND with{0002}texture more accurately.The obtained true stress-true plastic strain curves agreed well with the measured results in a wide range of strain rates and temperatures.The thermal softeninging,strain and strain rate hardening effect on the AZ31-ND with{0002}texture were discussed.The adiabatic shear band(ASB)of AZ31-ND with{0002}texture hat shaped specimen was successfully predicted by combining modified JC constitutive model and numerical simulation,which was also validated by Electron Back-Scattered Diffraction(EBSD)map under the same boundary condition.展开更多
The existing magnetomechancial models cannot explain the different experimental phenomena when the ferromagnetic specimen is respectively subjected to tension and compression stress in the constant and low intensity m...The existing magnetomechancial models cannot explain the different experimental phenomena when the ferromagnetic specimen is respectively subjected to tension and compression stress in the constant and low intensity magnetic field,especially in the compression case. To promote the development of magnetomechancial theory, the energy conservation equation, effective magnetic field equation, and anhysteretic magnetization equation of the original Jiles-Atherton(J-A)theory are elucidated and modified, an equation of the local equilibrium status is employed and the differential expression of the modified magnetomechancial model based on the modified J-A theory is established finally. The effect of stress and plastic deformation on the magnetic parameters is analyzed. An excellent agreement is achieved between the theoretic predictions by the present modified model and the previous experimental results. Comparing with the calculation results given by the existing models and experimental results, it is seen indeed that the modified magnetomechanical model can describe the different magnetization features during tension-release and compression-release processes much better, and is the only one which can accurately reflect the experimental observation that the magnetic induction intensity reverses to negative value with the increase of the compressive stress and applied field.展开更多
The conventional Kalman filter(CKF)is widely used in tightly-coupled INS/GPS integrated navigation systems.The linearization accuracy of the CKF observation model is one of the decisive factors of the estimation acc...The conventional Kalman filter(CKF)is widely used in tightly-coupled INS/GPS integrated navigation systems.The linearization accuracy of the CKF observation model is one of the decisive factors of the estimation accuracy and therefore navigation accuracy.Additionally,the conventional observation model(COM)used by the filter may be divergent,which would result into some terrible accuracies of INS/GPS integration navigation in some cases.To improve the navigation accuracy,the linearization accuracy of the COM still needs further improvement.To deal with this issue,the observation model is modified with the linearization of the range and range rate equations in this paper.Compared with COM,the modified observation model(MOM)further considers the difference between the real user position and the position calculated by SINS.To verify the advantages of this model,INS/GPS integrated navigation simulation experiments are conducted with the usage of COM and MOM respectively.According to the simulation results,the positions(velocities)calculated using COM are divergent over time while the others using MOM are convergent,which demonstrates the higher linearization accuracy of MOM.展开更多
The modified shear lag model proposed recently was applied to calculate thermal residual stresses and subsequent stress distributions under tensile and compressive loadings. The expressions for the elastic moduli and ...The modified shear lag model proposed recently was applied to calculate thermal residual stresses and subsequent stress distributions under tensile and compressive loadings. The expressions for the elastic moduli and the yield strengths under tensile and compressive loadings were derived which take account of thermal residual stresses. The asymmetries in the elastic modulus and the yield strength were interpreted using the derived expressions and the obtained results of the stress calculations. The model predictions have exhibited good agreements with the experimental results and also with the other theoretical predictions展开更多
In this study,through experimental research and an investigation on large datasets of the durability parameters in ocean engineering,the values,ranges,and types of distribution of the durability parameters employed fo...In this study,through experimental research and an investigation on large datasets of the durability parameters in ocean engineering,the values,ranges,and types of distribution of the durability parameters employed for the durability design in ocean engineering in northern China were confirmed.Based on a modified theoretical model of chloride diffusion and the reliability theory,the service lives of concrete structures exposed to the splash,tidal,and underwater zones were calculated.Mixed concrete proportions meeting the requirement of a service life of 100 or 120 years were designed,and a cover thickness requirement was proposed.In addition,the effects of the different time-varying relationships of the boundary condition(Cs)and diffusion coefficient(Df)on the service life were compared;the results showed that the time-varying relationships used in this study(i.e.,Cscontinuously increased and then remained stable,and Dfcontinuously decreased and then remained stable)were beneficial for the durability design of concrete structures in marine environment.展开更多
The strain effect on the critical current is one of the most important properties for polycrystalline YBa2 Cu3O7-δ (REBCO, RE: rare earth) films, in which the reversible effect is intrinsic in the range of strain ...The strain effect on the critical current is one of the most important properties for polycrystalline YBa2 Cu3O7-δ (REBCO, RE: rare earth) films, in which the reversible effect is intrinsic in the range of strain 0 and the irreversible strain εirr. By introducing the applied strain, a modified grain boundaries (GBs) in the REBCO film is developed. lattice model combining the strain and misorientation of A good agreement of the calculation on the lattice model with the experimental data shows that the lattice model is able to well describe the reversible effect of axial strain on the critical current of the REBCO film, and provides a good understanding of the mechanism of the reversible effect of the strain. Moreover, the effects of the crystallographic texture of the REBCO film and the residual strain εr on the variation of the critical current with the applied strain are extensively investigated. Furthermore by using the developed lattice model, the irreversible strain εirr of the REBCO film can be theoretically determined by comparing the calculation of the critical current-strain curve with the experimental data.展开更多
To understand and develop new nanostructure materials with specific mechanical properties, a good knowledge of the elastic strain response is mandatory. Here we investigate the linear elasticity response in the modifi...To understand and develop new nanostructure materials with specific mechanical properties, a good knowledge of the elastic strain response is mandatory. Here we investigate the linear elasticity response in the modified phase-field-crystal(MPFC) model. The results show that two different propagation modes control the elastic interaction length and time, which determine whether the density waves can propagate or not. By quantitatively calculating the strain field, we find that the strain distribution is indeed extremely uniform in case of elasticity. Further, we present a detailed theoretical analysis for the orientation dependence and temperature dependence of shear modulus. The simulation results show that the shear modulus reveals strong anisotropy and the one-mode analysis provides a good guideline for determining elastic shear constants until the system temperature falls below a certain value.展开更多
Background: The deep understanding of pathogenesis is a key moment in the formation of the modern strategy of modern medicine. We conducted the thorough analysis of the microscopic processes occurring in the bodies of...Background: The deep understanding of pathogenesis is a key moment in the formation of the modern strategy of modern medicine. We conducted the thorough analysis of the microscopic processes occurring in the bodies of patients with purulent-septic complications. The modified pathogenetic concept of the diagnostic and treatment model of diseases with septic complications is presented. The obtained information about the mechanisms of origin and development of these diseases is fundamentally important for finding the modern effective methods of treating patients. The aim of the research is to modify treatment tactics for patients with sepsis and burn injuries based on the modified pathogenetic concept using modern diagnostics, i.e. the method of fluorescence spectroscopy (MFS) and biomarkers. Materials and Methods: The proposed modified pathogenetic concept of the diagnostic and treatment model of diseases with purulent-septic complications along with standard methods was used successfully for effective treatment of 15 patients with sepsis and 25 with burn injuries. Results: 3 main scenarios of behaviour of spectral-fluorescence characteristics of patients with sepsis are illustrated. Spectral-fluorescence markers of sepsis were studied, which are informative 24 to 48 hours before the appearance of obvious clinical and laboratory signs of significant changes in the general somatic status of patients. Conclusions: The proposed diagnostic and therapeutic approach is new and fundamentally important for diagnostics and monitoring of the process of treatment of patients with purulent-septic diseases and burn injuries. An in-depth understanding of the dynamics of septic complications and the corresponding changes of the main markers of these diseases during treatment is especially relevant. The use of infusion therapy with solutions of donor albumin as an effective pathogenetic treatment is scientifically justified.展开更多
The dynamic behavior of the stranded wire helical spring is described by a modified Bouc-Wen model while the model parameters must be identified using an identification method and experimental data. Existing identific...The dynamic behavior of the stranded wire helical spring is described by a modified Bouc-Wen model while the model parameters must be identified using an identification method and experimental data. Existing identification methods usually relies either solely nonlinear iterative algorithms or manually trial and error. Therefore, the identification process can be rather time consuming and effort taking. As a result, these methods are not ideal for engineering applications. To come up with a more practical method, a three-stage identification method is proposed. Periodic loading and identification simulations are carried out to verify the effectiveness of the proposed method. Noises are added to the simulated data to test the performance of the proposed method when dealing with noise contaminated data. The simulation results indicate that the proposed method is able to give satisfying results when the noise levels are set to be 0.01, 0.03, 0.05 and 0.07. In addition, the proposed method is also applied to experimental data and compared with an existing method. The experimental data is acquired through a periodic loading test. The experiment results suggest that the proposed method features better accuracy compared with the existing method. An effective approach is proposed for identifying the model parameters of the stranded wire helical spring.展开更多
The existing engineering empirical life analysis models are not capable of considering the constitutive behavior of materials under contact loads;as a consequence,these methods may not be accurate to predict fatigue l...The existing engineering empirical life analysis models are not capable of considering the constitutive behavior of materials under contact loads;as a consequence,these methods may not be accurate to predict fatigue lives of roll-ing bearings.In addition,the contact stress of bearing in operation is cyclically pulsating,it also means that the bear-ing undergo non-symmetrical fatigue loadings.Since the mean stress has great effects on fatigue life,in this work,a novel fatigue life prediction model based on the modified SWT mean stress correction is proposed as a basis of which to estimate the fatigue life of rolling bearings,in which,takes sensitivity of materials and mean stress into account.A compensation factor is introduced to overcome the inaccurate predictions resulted from the Smith,Watson,and Topper(SWT)model that considers the mean stress effect and sensitivity while assuming the sensitivity coefficient of all materials to be 0.5.Moreover,the validation of the model is finalized by several practical experimental data and the comparison to the conventional SWT model.The results show the better performance of the proposed model,especially in the accuracy than the existing SWT model.This research will shed light on a new direction for predicting the fatigue life of rolling bearings.展开更多
The contact sti ness of a mechanical bonding surface is an important parameter in determining the normal and radial contact force. To improve the calculation accuracy of the contact force model, the surface roughness ...The contact sti ness of a mechanical bonding surface is an important parameter in determining the normal and radial contact force. To improve the calculation accuracy of the contact force model, the surface roughness of the bonding surface and the energy loss that necessarily occurs during the impact process should be considered com?prehensively. To study the normal contact force of a revolute joint with clearance more accurately in the case of dry friction, a nonlinear sti ness coe cient model considering the surface roughness was established based on fractal theory, which considers the elastic, elastic?plastic, and plastic deformations of the asperities of the contact surface during the contact process. On this basis, a modified nonlinear spring damping model was established based on the Lankarani–Nikravesh contact force model. The laws influencing the surface roughness, recovery coe cient, initial velocity, and clearance size on the impact force were revealed, and were compared with the Lankarani–Nikravesh model and a hybrid model using MATLAB. The maximum impact force was obtained using a modified contact force model under di erent initial velocities, di erent clearances, and di erent degrees of surface roughness, and the calculated results were then compared with the experiment results. This study indicates that the modified model can be used more widely than other models, and is suitable for both large and small clearances. In particular, the modified model is more accurate when calculating the contact force of a revolute joint with a small clearance.展开更多
基金supported by the National Natural Science Foundation of China (Grant Nos. 51874183 and 51874182)the National Key Research and Development Program of China (Grant No. 2018YFC0809300)。
文摘The subway is the primary travel tool for urban residents in China. Due to the complex structure of the subway and high personnel density in rush hours, subway evacuation capacity is critical. The subway evacuation model is explored in this work by combining the improved social force model with the view radius using the Vicsek model. The pedestrians are divided into two categories based on different force models. The first category is sensitive pedestrians who have normal responses to emergency signs. The second category is insensitive pedestrians. By simulating different proportions of the insensitive pedestrians, we find that the escape time is directly proportional to the number of insensitive pedestrians and inversely proportional to the view radius. However, when the view radius is large enough, the escape time does not change significantly, and the evacuation of people in a small view radius environment tends to be integrated. With the improvement of view radius conditions, the escape time changes more obviously with the proportion of insensitive pedestrians. A new emergency sign layout is proposed, and the simulations show that the proposed layout can effectively reduce the escape time in a small view radius environment. However, the evacuation effect of the new escape sign layout on the large view radius environment is not apparent. In this case, the exit setting emerges as an additional factor affecting the escape time.
基金supported by Fundamental Research Program of Shanxi Province(20210302123055)and(201801D221035).
文摘In order to theoretically study the growth morphology of dihydroxylammonium 5,5’-bistetrazole-1,1’-dio late(TKX-50)crystal in different solvent systems,crystal–solvent models were established,and then molecular dynamics(MD)methods were adopted as a means to simulate particle motion.Modified attachment energy(MAE)model was employed to calculate the growth morphology of TKX-50.The simulation results demonstrate that COMPASS force field and RESP charge are suitable for molecular dynamics simulation of TKX-50.The morphologically dominant growth surfaces of TKX-50 in vacuum are(020),(011),(11–1),(100)and(120),respectively.In water(H_(2)O)and N,N-dimethylformamide(DMF)solvents,the(11–1)face is the largest in the habit face,the growth rate of(020)face becomes faster.With the increase of temperature,the aspect ratios of TKX-50 crystal in DMF solvent increase,and the areas of the(120)faces decrease.In ethylene glycol/H_(2)O mixed solvent system with volume ratio of 1/1,aspect ratio of TKX-50 is relatively small.In formic acid/H_(2)O mixed solvents with different volume ratios(1/4,1/3,1/2,1/1 and 2/1),aspect ratio of TKX-50 is relatively small when volume ratio is 1/2.
基金supported by the National Natural Science Foundation of China (Grants No. 51179075 and 51239005) A Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions
文摘Considering the compressibility of the cavity in the cavitating flow, this paper presents a modified k-ω model for predicting the cavitating flow in a centrifugal pump, in which the modified k-ω model and Schnerr-Sauer cavitation model were combined with ANSYS CFX. To evaluate the modified and standard k-co models, numerical simulations were performed with these two models, respectively, and the calculation results were compared with the experimental data. Numerical simulations were executed with three different values of the flow coefficient, and the simulation results of the modified k-ω model showed agreement with most of the experimental data. The cavitating flow in the centrifugal pump obtained by the modified k-ω model at the design flow coefficient of 0.102, was analyzed. When the cavitation number decreases, the cavity initially generates on the suction side of the blade near the leading edge and then expands to the outlet of the impeller, and the decrease of the total pressure coefficient mainly occurs upstream of the impeller passage, while the downstream remains almost unaffected by the development of cavitation.
文摘AIM:To explore the related risk factors for diabetic retinopathy(DR)in type 2 diabetes with insulin therapy.METHODS:We studied the relationships among blood glucose,serum C-peptide,plasma insulin,beta-cell function and the development of DR.Beta-cell function was assessed by a modified homeostasis model assessment(modified HOMA)which was gained by using C-peptide to replace insulin in the homeostasis model assessment(HOMA)of beta-cell function.We also studied the relationships between modified HOMA index and serum C-peptide response to 100 g tasteless steamed bread to determine the accuracy of modified HOMA.RESULTS:Our study group consisted of 170 type 2diabetic inpatients with DR(age:58.35±13.87y,mean±SD)and 205 type 2 diabetic inpatients with no DR(NDR)(age:65.52±11.59y).DR patients had higher age,longer diabetic duration,higher hypertension grade,higher postprandial plasma glucose,higher fluctuation level of plasma glucose,lower body mass index(BMI),lower postprandial serum insulin and C-peptide,lower fluctuation level of serum insulin and C-peptide(P【0.05).In our logistic regression model,duration of diabetes,hypertension grade,fasting plasma insulin and glycosylated hemoglobin(HbA1C)were significantly associated with the presence of DR after adjustment for confounding factors(P【0.05).CONCLUSION:Our results suggested although modified HOMA showed significant correlation to the occurrence of DR on Spearman’s rank-correlationanalysis,logistic regression showed no significant association between these two variables after adjustment for relevant confounding factors(such as age,sex,duration of diabetes,BMI,hypertension grade,HbA1C,plasma insulin).Duration of diabetes,hypertension grade,fasting plasma insulin and HbA1C were independently associated with the development of DR in Chinese type 2 diabetics.
基金Special Fund of Marine Commonweal Industry under contact Nos 201105016 and 201205007supported by National Marine Environment Forecasting Centrethe National Natural Science Foundation of China under contact No.41176012
文摘Considering the discontinuous characteristics of sea ice on various scales,a modified discrete element model(DEM) for sea ice dynamics is developed based on the granular material rheology.In this modified DEM,a soft sea ice particle element is introduced as a self-adjustive particle size function.Each ice particle can be treated as an assembly of ice floes,with its concentration and thickness changing to variable sizes under the conservation of mass.In this model,the contact forces among ice particles are calculated using a viscous-elastic-plastic model,while the maximum shear forces are described with the Mohr-Coulomb friction law.With this modified DEM,the ice flow dynamics is simulated under the drags of wind and current in a channel of various widths.The thicknesses,concentrations and velocities of ice particles are obtained,and then reasonable dynamic process is analyzed.The sea ice dynamic process is also simulated in a vortex wind field.Taking the influence of thermodynamics into account,this modified DEM will be improved in the future work.
基金Project(1301015A)supported by the Post-doctoral Research Fund of Jiangsu Province,ChinaProject Funded by the Priority Academic Program of Jiangsu Higher Education Institution,China+1 种基金Project(2014M561566)supported by China Postdoctoral Science FoundationProject(YK913007)supported by Key Laboratory of Earth-Rock Dam Failure Mechanism and Safety Control Technologies,China
文摘Two modifications for the basic Barcelona model(BBM) are present. One is the replacement of the net stress by the average skeleton stress in unsaturated soil modeling, and the other is the adoption of an expression for the load-collapse(LC) yield surface that can match flexibly the normal compression lines at different suctions. The predictions of the modified BBM for the controlled-suction triaxial test on the unsaturated compacted clay are presented and compared with the experimental results. A good agreement between the predicted and experimental results demonstrates the reasonability of the modified BBM. On this basis, the coupled processes of groundwater flow and soil deformation in a homogeneous soil slope under a long heavy rainfall are simulated with the proposed elasto-plastic model. The numerical results reveal that the failure of a slope under rainfall infiltration is due to both the reduction of soil suction and the significant rise in groundwater table. The evolution of the displacements is greatly related to the change of suction. The maximum collapse deformation happens near the surface of slope where infiltrated rainwater can quickly reach. The results may provide a helpful reference for hazard assessment and control of rainfall-induced landslides.
文摘The modified sub regular solution model was used for a calculation of the activity coefficient of immiscible binary alloy systems. The parameters needed for the calculation are the interaction parameters, λ 1 and λ 2, which are represented as a linear function of temperature, T . The molar excess Gibbs free energy, G m E, can be written in the form G m E= x A x B[( λ 11 + λ 12 T )+( λ 21 + λ 22 T ) x B ] The calculation is carried out numerically for three immiscible binary alloy systems, Al Pb, Cu Tl and In V. The agreement between the calculated and experimentally determined values of activity coefficient is excellent.
基金Supported by the National Key Scientific Instrument and Equipment Development Projects of China under Grant No 81127901the National Natural Science Foundation of China under Grant Nos 61372017 and 30970828
文摘A modified Monte Carlo model of speckle tracking of shear wave propagation in scattering media is proposed. The established Monte Carlo model mainly concerns the variations of optical electric field and speckle. The two- dimensional intensity distribution and the time evolution of speckles in different probe locations are obtained. The fluctuation of speckle intensity tracks the acoustic-radiation-force shear wave propagation, and especially the reduction of speckle intensity implies attenuation of shear wave. Then, the shear wave velocity is estimated quantitatively on the basis of the time-to-peak algorithm and linear regression processing. The results reveal that a smaller sampling interval yields higher estimation precision and the shear wave velocity is estimated more efficiently by using speckle intensity difference than by using speckle contrast difference according to the estimation error. Hence, the shear wave velocity is estimated to be 2.25 m/s with relatively high accuracy for the estimation error reaches the minimum (0.071).
文摘A simple modified analytic EAM model for bcc Fe and fcc Al was used to calculate the lattice constant and elastic constants of B2 FeAl and DO3 Fe3Al alloys. The formation energies of vacancy and antisite were also calculated. The present calculations are in agreement with the experimental data and the theoretical results obtained by other authors.
基金This work was supported by Surface of the State Natural Science Fund Projects(No.51571145)City of Ningbo“science and technology innovation 2025”major special project(new energy vehicle lightweight magnesium alloy material precision forming technology).
文摘The dynamic compression experiments with Split-Hopkinson Pressure Bar(SHPB)were performed on AZ31 magnesium alloy rolled sheet specimens in the normal direction(AZ31-ND)with{0002}texture at the temperature of 293-523 K and the strain rate of 0.001-2200 s^−1.The temperature term in Johnson-Cook(JC)constitutive model had been reasonably modified.This advantage made constitutive model promising for decribing the dynamic deformation behavior of AZ31-ND with{0002}texture more accurately.The obtained true stress-true plastic strain curves agreed well with the measured results in a wide range of strain rates and temperatures.The thermal softeninging,strain and strain rate hardening effect on the AZ31-ND with{0002}texture were discussed.The adiabatic shear band(ASB)of AZ31-ND with{0002}texture hat shaped specimen was successfully predicted by combining modified JC constitutive model and numerical simulation,which was also validated by Electron Back-Scattered Diffraction(EBSD)map under the same boundary condition.
基金Project supported by the Major Program of Sichuan Province Science and Technology Plan,China(Grant No.2015SZ0010)the Scientific Research Foundation of Sichuan Province,China(Grant No.2014GZ0121)
文摘The existing magnetomechancial models cannot explain the different experimental phenomena when the ferromagnetic specimen is respectively subjected to tension and compression stress in the constant and low intensity magnetic field,especially in the compression case. To promote the development of magnetomechancial theory, the energy conservation equation, effective magnetic field equation, and anhysteretic magnetization equation of the original Jiles-Atherton(J-A)theory are elucidated and modified, an equation of the local equilibrium status is employed and the differential expression of the modified magnetomechancial model based on the modified J-A theory is established finally. The effect of stress and plastic deformation on the magnetic parameters is analyzed. An excellent agreement is achieved between the theoretic predictions by the present modified model and the previous experimental results. Comparing with the calculation results given by the existing models and experimental results, it is seen indeed that the modified magnetomechanical model can describe the different magnetization features during tension-release and compression-release processes much better, and is the only one which can accurately reflect the experimental observation that the magnetic induction intensity reverses to negative value with the increase of the compressive stress and applied field.
基金Supported by the National Natural Science Foundation of China(61502257,41304031)
文摘The conventional Kalman filter(CKF)is widely used in tightly-coupled INS/GPS integrated navigation systems.The linearization accuracy of the CKF observation model is one of the decisive factors of the estimation accuracy and therefore navigation accuracy.Additionally,the conventional observation model(COM)used by the filter may be divergent,which would result into some terrible accuracies of INS/GPS integration navigation in some cases.To improve the navigation accuracy,the linearization accuracy of the COM still needs further improvement.To deal with this issue,the observation model is modified with the linearization of the range and range rate equations in this paper.Compared with COM,the modified observation model(MOM)further considers the difference between the real user position and the position calculated by SINS.To verify the advantages of this model,INS/GPS integrated navigation simulation experiments are conducted with the usage of COM and MOM respectively.According to the simulation results,the positions(velocities)calculated using COM are divergent over time while the others using MOM are convergent,which demonstrates the higher linearization accuracy of MOM.
文摘The modified shear lag model proposed recently was applied to calculate thermal residual stresses and subsequent stress distributions under tensile and compressive loadings. The expressions for the elastic moduli and the yield strengths under tensile and compressive loadings were derived which take account of thermal residual stresses. The asymmetries in the elastic modulus and the yield strength were interpreted using the derived expressions and the obtained results of the stress calculations. The model predictions have exhibited good agreements with the experimental results and also with the other theoretical predictions
基金financial support provided by the National Natural Science Foundation of China(51508272,11832013,51878350,and 51678304)。
文摘In this study,through experimental research and an investigation on large datasets of the durability parameters in ocean engineering,the values,ranges,and types of distribution of the durability parameters employed for the durability design in ocean engineering in northern China were confirmed.Based on a modified theoretical model of chloride diffusion and the reliability theory,the service lives of concrete structures exposed to the splash,tidal,and underwater zones were calculated.Mixed concrete proportions meeting the requirement of a service life of 100 or 120 years were designed,and a cover thickness requirement was proposed.In addition,the effects of the different time-varying relationships of the boundary condition(Cs)and diffusion coefficient(Df)on the service life were compared;the results showed that the time-varying relationships used in this study(i.e.,Cscontinuously increased and then remained stable,and Dfcontinuously decreased and then remained stable)were beneficial for the durability design of concrete structures in marine environment.
基金Supported by the National Natural Science Foundation of China under Grant No 11372096the Research Fund for the Doctoral Program of Higher Education of China
文摘The strain effect on the critical current is one of the most important properties for polycrystalline YBa2 Cu3O7-δ (REBCO, RE: rare earth) films, in which the reversible effect is intrinsic in the range of strain 0 and the irreversible strain εirr. By introducing the applied strain, a modified grain boundaries (GBs) in the REBCO film is developed. lattice model combining the strain and misorientation of A good agreement of the calculation on the lattice model with the experimental data shows that the lattice model is able to well describe the reversible effect of axial strain on the critical current of the REBCO film, and provides a good understanding of the mechanism of the reversible effect of the strain. Moreover, the effects of the crystallographic texture of the REBCO film and the residual strain εr on the variation of the critical current with the applied strain are extensively investigated. Furthermore by using the developed lattice model, the irreversible strain εirr of the REBCO film can be theoretically determined by comparing the calculation of the critical current-strain curve with the experimental data.
基金Project supported by the National Natural Science foundation of China(Grant Nos.51571165 and 51371151)Special Program for Applied Research on Super Computation of the NSFC-Guangdong Joint Fund(the second phase),Chinathe Fundamental Research Funds for the Central Universities,China(Grant No.3102015BJ(II)ZS001)
文摘To understand and develop new nanostructure materials with specific mechanical properties, a good knowledge of the elastic strain response is mandatory. Here we investigate the linear elasticity response in the modified phase-field-crystal(MPFC) model. The results show that two different propagation modes control the elastic interaction length and time, which determine whether the density waves can propagate or not. By quantitatively calculating the strain field, we find that the strain distribution is indeed extremely uniform in case of elasticity. Further, we present a detailed theoretical analysis for the orientation dependence and temperature dependence of shear modulus. The simulation results show that the shear modulus reveals strong anisotropy and the one-mode analysis provides a good guideline for determining elastic shear constants until the system temperature falls below a certain value.
文摘Background: The deep understanding of pathogenesis is a key moment in the formation of the modern strategy of modern medicine. We conducted the thorough analysis of the microscopic processes occurring in the bodies of patients with purulent-septic complications. The modified pathogenetic concept of the diagnostic and treatment model of diseases with septic complications is presented. The obtained information about the mechanisms of origin and development of these diseases is fundamentally important for finding the modern effective methods of treating patients. The aim of the research is to modify treatment tactics for patients with sepsis and burn injuries based on the modified pathogenetic concept using modern diagnostics, i.e. the method of fluorescence spectroscopy (MFS) and biomarkers. Materials and Methods: The proposed modified pathogenetic concept of the diagnostic and treatment model of diseases with purulent-septic complications along with standard methods was used successfully for effective treatment of 15 patients with sepsis and 25 with burn injuries. Results: 3 main scenarios of behaviour of spectral-fluorescence characteristics of patients with sepsis are illustrated. Spectral-fluorescence markers of sepsis were studied, which are informative 24 to 48 hours before the appearance of obvious clinical and laboratory signs of significant changes in the general somatic status of patients. Conclusions: The proposed diagnostic and therapeutic approach is new and fundamentally important for diagnostics and monitoring of the process of treatment of patients with purulent-septic diseases and burn injuries. An in-depth understanding of the dynamics of septic complications and the corresponding changes of the main markers of these diseases during treatment is especially relevant. The use of infusion therapy with solutions of donor albumin as an effective pathogenetic treatment is scientifically justified.
基金Supported by National Natural Science Foundation of China(Grant Nos.51375508,51375517)the Key Technologies R&D Program of China(Grant No.2012BAF12B09)the Program for Changjiang Scholars and Innovative Research Team in University of Ministry of Education of China(Grant No.IRT1196)
文摘The dynamic behavior of the stranded wire helical spring is described by a modified Bouc-Wen model while the model parameters must be identified using an identification method and experimental data. Existing identification methods usually relies either solely nonlinear iterative algorithms or manually trial and error. Therefore, the identification process can be rather time consuming and effort taking. As a result, these methods are not ideal for engineering applications. To come up with a more practical method, a three-stage identification method is proposed. Periodic loading and identification simulations are carried out to verify the effectiveness of the proposed method. Noises are added to the simulated data to test the performance of the proposed method when dealing with noise contaminated data. The simulation results indicate that the proposed method is able to give satisfying results when the noise levels are set to be 0.01, 0.03, 0.05 and 0.07. In addition, the proposed method is also applied to experimental data and compared with an existing method. The experimental data is acquired through a periodic loading test. The experiment results suggest that the proposed method features better accuracy compared with the existing method. An effective approach is proposed for identifying the model parameters of the stranded wire helical spring.
基金This study is financially supported by the National Natural Science Foundation of China(Grant No.51875089).
文摘The existing engineering empirical life analysis models are not capable of considering the constitutive behavior of materials under contact loads;as a consequence,these methods may not be accurate to predict fatigue lives of roll-ing bearings.In addition,the contact stress of bearing in operation is cyclically pulsating,it also means that the bear-ing undergo non-symmetrical fatigue loadings.Since the mean stress has great effects on fatigue life,in this work,a novel fatigue life prediction model based on the modified SWT mean stress correction is proposed as a basis of which to estimate the fatigue life of rolling bearings,in which,takes sensitivity of materials and mean stress into account.A compensation factor is introduced to overcome the inaccurate predictions resulted from the Smith,Watson,and Topper(SWT)model that considers the mean stress effect and sensitivity while assuming the sensitivity coefficient of all materials to be 0.5.Moreover,the validation of the model is finalized by several practical experimental data and the comparison to the conventional SWT model.The results show the better performance of the proposed model,especially in the accuracy than the existing SWT model.This research will shed light on a new direction for predicting the fatigue life of rolling bearings.
基金Supported by National Natural Science Foundation of China(Grant No.51775475)Hebei Provincial Natural Science Foundation of China(Grant No.E2016203463)
文摘The contact sti ness of a mechanical bonding surface is an important parameter in determining the normal and radial contact force. To improve the calculation accuracy of the contact force model, the surface roughness of the bonding surface and the energy loss that necessarily occurs during the impact process should be considered com?prehensively. To study the normal contact force of a revolute joint with clearance more accurately in the case of dry friction, a nonlinear sti ness coe cient model considering the surface roughness was established based on fractal theory, which considers the elastic, elastic?plastic, and plastic deformations of the asperities of the contact surface during the contact process. On this basis, a modified nonlinear spring damping model was established based on the Lankarani–Nikravesh contact force model. The laws influencing the surface roughness, recovery coe cient, initial velocity, and clearance size on the impact force were revealed, and were compared with the Lankarani–Nikravesh model and a hybrid model using MATLAB. The maximum impact force was obtained using a modified contact force model under di erent initial velocities, di erent clearances, and di erent degrees of surface roughness, and the calculated results were then compared with the experiment results. This study indicates that the modified model can be used more widely than other models, and is suitable for both large and small clearances. In particular, the modified model is more accurate when calculating the contact force of a revolute joint with a small clearance.