Comparison of Entropy vs. Bispectral Index Anesthetic Depth Monitoring during Isoflurane Anesthesia in Living Donor Liver Transplantation: Observational Study

Liver transplantation (LT) recipients are known to require less anesthetic agents. Providing minimally required anesthetics while avoiding awareness is especially important in LT recipients because it would help manage perioperative hemodynamic instability with less vasopressor and fast track recovery. This study aims to compare state entropy (SE) against bispectral index (BIS) during isoflurane anesthesia in LT. We adjusted anesthesia to BIS values 40 - 60, and compared it with concomitant SE values. BIS, SE values, and anesthetic requirements according to liver failure severity, etiology and LT stages were analyzed. For BIS-SE differences, SE value that is different from the concomitant BIS by more than 15 was defined as a significant disagreement. Mann Whitney, Kruskal Wallis test and a Poisson exact test were used for analysis. The BIS-SE pair sets of 2895 from 38 patients were analyzed. BIS, SE values and anesthetic requirements were significantly lower in MELD ≥ 20 (p < 0.001 in all) and in alcoholic etiology (p < 0.001 in all). For BIS-SE differences, 320 disagreement data pairs were seen at a rate of 1.33 times/hr (95% CI = [1.19, 1.48], p < 0.001). A significant disagreement was delineated in MELD score ≥ 20 (3.04 times/hr, CI = [2.64, 3.49], p < 0.001), alcoholic etiology (3.19 times/hr, [2.67, 3.78], p < 0.001) and postreperfusion stage (1.63 times/hr, [1.43, 1.85], p < 0.001). In these significant BIS-SE differences, 95.9% (307/320 disagreement data pairs) showed higher BIS than SE. In conclusion, in high MELD and alcoholic etiology, anesthetic requirements were significantly less, and BIS and SE showed great discrepancy with lower SE values. Therefore, when SE monitoring is used during LT, anesthesiologists may need to consider that in high MELD and alcoholic etiology, SE tends to show lower values than the concomitant BIS values that are within optimal anesthetic depth ranges.

Deformation warning index for reinforced concrete dam based on structural health monitoring data and numerical simulation

The material mechanical parameters of the dam body and foundation will change when a dam is reinforced during the aging process.This causes significant changes in the structural state of the project and makes it difficult to ensure its structural safety.In this study,a new deformation warning index for reinforced concrete dams was developed according to the prototype monitoring data,statistical models,three-dimensional finite element model(FEM)numerical simulation,and the critical conditions of the dam structure.A statistical model was established to separate the water pressure component.Then,a three-dimensional FEM of the reinforced concrete dam was constructed to simulate the water pressure component.Furthermore,the deformation components that affected the mechanical parameters of the dam under the same amount of reservoir water level change were separated and quantified accurately.In addition,the method for inversion of comprehensive mechanical parameters after dam reinforcement was used.The influence mechanisms of the deformation behavior of concrete dams under the reservoir water level and temperature changes were investigated.A new deformation warning index was developed by combining the forward-simulated critical water pressure component and temperature component in the period of extreme temperature decrease with the aging component separated by the statistical model.The new deformation warning index considers the structural state of the dam before and after reinforcement and links the structural strength criterion and the deformation evolution mechanisms.It provides a theoretical foundation and decision support for long-term service and operation management of reinforced dams.

Bispectral index monitoring as an adjunct to nurse-administered combined sedation during endoscopic retrograde cholangiopancreatography

AIM:To determine whether bispectral index (BIS) monitoring is useful for propofol administration for deep sedation during endoscopic retrograde cholangiopancreatography (ERCP). METHODS:Fifty-nine consecutive patients with a variety of reasons for ERCP who underwent the procedure at least twice between 1 July 2010 and 30 November 2010. This was a randomized cross-over study, in which each patient underwent ERCP twice, once with BIS monitoring and once with control monitoring. Whether BIS monitoring was done during the first or second ERCP procedure was random. Patients were intermittently administered a mixed regimen including midazolam, pethidine, and propofol by trained nurses. The nurse used a routine practice to monitor sedation using the Modified Observer's Assessment of Alertness/Sedation (MOAA/S) scale or the BIS monitoring. The total amount of midazolam and propofol used and serious side effects were compared between the BIS and control groups. RESULTS:The mean total propofol dose administered was 53.1 ± 32.2 mg in the BIS group and 54.9 ± 30.8 mg in the control group (P = 0.673). The individual propofol dose received per minute during the ERCP procedure was 2.90 ± 1.83 mg/min in the BIS group and 3.44 ± 2.04 mg in the control group (P = 0.103). The median value of the MOAA/S score during the maintenance phase of sedation was comparable for the two groups. The mean BIS values throughout the procedure (from insertion to removal of the endoscope) were 76.5 ± 8.7 for all 59 patients in using the BIS monitor. No significant differences in the frequency of < 80% oxygen saturation, hypotension (< 80 mmHg), or bradycardia (< 50 beats/min) were observed between the two study groups. Four cases of poor cooperation occurred, in which the procedure should be stopped to add the propofol dose. After adding the propofol, the procedure could be conducted successfully (one case in the BIS group, three cases in the control group). The endoscopist rated patient sedation as excellent for all patients in both groups. All patients in both groups rated their level of satisfaction as high (no discomfort). During the post-procedural follow-up in the recovery area, no cases of clinically significant hypoxic episodes were recorded in either group. No other postoperative side effects related to sedation were observed in either group. CONCLUSION:BIS monitoring trend to slighlty reduce the mean propofol dose. Nurse-administered propofol sedation under the supervision of a gastroenterologist may be considered an alternative under anesthesiologist.

Establishment of Monitoring and Assessment Index System of Land Degradation of Farmland Ecosystems at Small-scale

The research established land degradation monitoring and assessment in- dex system of farmland ecosystem under influence of human activities, including farming system, measures, mulch residuals, fertilizer pollutions, pesticide pollution, irrigation method, salt content of soils, engineering measures of discharging alkali, agricultural protection forests and poverty. The indices of the system are accessible, and convenient for operation, which is suitable for land managers self-monitoring, re- ducing irrational farming activities, improving farmland productivity and preventing farmland degradation.

Wearable Smart Sensor System for Medical Monitoring with an Assessment of the Level of Blood Loss and Pain Shock Because of Trauma or Injury

Blood loss in peacetime is mainly due to the normal menstrual cycle in women or diseases with surgical intervention. In wartime, blood loss in military personnel is a characteristic sign of a closed or open injury of the body during internal or external bleeding. Access to clinical care for wounded military personnel injured on the battlefield is limited and has long delays compared to patients in peacetime. Most of the deaths of wounded military personnel on the battlefield occur within the first hour after being wounded. The most common causes are delay in providing medical care, loss of time for diagnosis, delay in stabilization of pain shock and large blood loss. Some help in overcoming these problems is provided by the data in the individual capsule, which each soldier of the modern army possesses;however, data in an individual capsule is not sufficient to provide emergency medical care in field and hospital conditions. This paper considers a project for development of a smart real-time monitoring wearable system for blood loss and level of shock stress in wounded persons on the battlefield, which provides medical staff in field and hospital conditions with the necessary information to give timely medical care. Although the hospital will require additional information, the basic information about the victims will already be known before he enters the hospital. It is important to emphasize that the key term in this approach is monitoring. It is tracking, and not a one-time measurement of indicators, that is crucial in a valid definition of bleeding.

Monitoring the Sequential Cropping Index of Arable Land in Zhejiang Province of China Using MODIS-NDVI

The sequential cropping index of arable land is important agricultural information. The aim of this article is to monitor and analyze the parameter, and offer reference for agricultural production. The cropping index of arable land in Zhejiang Province, China from 2001 to 2004 was calculated using the second order difference based MODIS （moderate resolution imagine spectroradimeter） vegetation data from NASA （National Aeronautic and Space Administration） in America and the land use map with a scale of 1：25 000. It was found that the peak of the time series of the NDVI curve indicated that the ground biomass of crops reached the maximum, and fluctuated with the crops growing processes such as sowing, seeding, heading, ripeness, and harvesting within one year. Thus, the sequential cropping index was defined as the number of peaks of the time series of the NDVI curve. The sequential cropping index of all cities in Zhejiang Province, China was worked out. It is seen from the spatial distribution that the cropping index in the southwest Zhejiang Province is larger than that in the northeast. As for the temporal distribution, the sequential cropping index decreased from 2001 to 2003, whereas it increased slightly from 2003 to 2004. However, the index of arable land was relatively low, as far as the geographic position and climatic resource were concerned, and the potential of the sequential cropping index was great.

An improved temperature vegetation dryness index(iTVDI) and its applicability to drought monitoring

Using Moderate Resolution Imaging Spectroradiometer(MODIS) data from the dry season during 2010–2012 over the whole Yunnan Province, an improved temperature vegetation dryness index(iTVDI), in which a parabolic dry-edge equation replaces the traditional linear dry-edge equation, was developed, to reveal the regional drought regime in the dry season. After calculating the correlation coefficient, root-mean-square error, and standard deviation between the iTVDI and observed topsoil moisture at 10 and 20 cm for seven sites, the effectiveness of the new index in depicting topsoil moisture conditions was verified. The drought area indicated by iTVDI mapping was then compared with the drought-affected area reported by the local government. The results indicated that the iTVDI can monitor drought more accurately than the traditional TVDI during the dry season in Yunnan Province. Using iTVDI facilitates drought warning and irrigation scheduling, and the expectation is that this new index can be broadly applied in other areas.

Research on the Seepage Safety Monitoring Indexes of the High Core Rockfill Dam

The study on developing the reasonable safety monitoring indexes plays a most importantly role in the health monitoring of high core rockfill dams. However, researches on this topic are relatively scarce both at home and abroad. In this paper, the characteristics and failure modes of seepage in high core rockfill dam are analyzed firstly. Then, a safety monitoring index based on seepage quantity, which reflects the overall seepage behavior, is developed, using the real-time monitoring data and its safety monitoring model. Moreover, another safety monitoring index based on seepage gradient, reflecting the local seepage behavior, is proposed, combining the spatial layout of osmo- meters and local failure mechanisms of core wall. Additionally, one more safety monitoring index based on permeability coefficient, which considers the overall and local seepage behaviors, is developed, on the basis of establishing the finite element analysis model and real-time seepage coefficient inversion analysis model of high core rockfill dam. A case study on these indexes of Nuozhadu high core rockfill dam is developed, which improves the reliability of seepage safety evaluation of the dam.

The Bispectral Index Interest during General Anesthesia at the University Hospital of Parakou (Republic of Benin) in 2019

Background: The bispectral index (BIS) derived from the electroencephalogram is an additional means of monitoring the depth of narcosis. Objective: To compare the monitoring of the depth of narcosis by the BIS associated with clinical data versus standard monitoring at the University Hospital of Parakou in Benin in 2019. Methods: This was an observational study for descriptive and analytical purposes with prospective data collection, carried out in general surgery and intensive care unit for 4 months. The inclusion criteria were: an age ≥ 18 years, an ASA score ≤ 3, surgery under general anesthesia and informed consent of the patient. Two groups were formed: non-BIS group monitored by clinical parameters (PA, FC, FR, EtCO2, and SpO2) only and BIS group monitored by bispectral index in addition to clinical parameters. Patients were seen 48 hours after the procedure. Results: 36 patients were collected. The mean age was 40.63 ± 16.77 years with a sex ratio of 3. ASA 1 patients represented 86.11% of the sample and ASA2 patients 13.89%. The average doses of Propofol were not significantly reduced in the BIS group (p = 0.555). On the other hand, the period of intraoperative recovery (p-value = 0.007) and the NVPO (p = 0.043;OR = 0.10;95% CI [0.01 - 0.97]) were significantly reduced by the use of BIS. One case of intraoperative memorization (2.78%) was however found in the BIS group. Conclusion: The bispectral index makes it possible to significantly reduce the risk of intraoperative awakening and PONV, and not significantly reduce the consumption of Propofol.

A hybrid specific index-related process monitoring strategy based on a novel two-step information extraction method

A two-step information extraction method is presented to capture the specific index-related information more accurately.In the first step,the overall process variables are separated into two sets based on Pearson correlation coefficient.One is process variables strongly related to the specific index and the other is process variables weakly related to the specific index.Through performing principal component analysis(PCA)on the two sets,the directions of latent variables have changed.In other words,the correlation between latent variables in the set with strong correlation and the specific index may become weaker.Meanwhile,the correlation between latent variables in the set with weak correlation and the specific index may be enhanced.In the second step,the two sets are further divided into a subset strongly related to the specific index and a subset weakly related to the specific index from the perspective of latent variables using Pearson correlation coefficient,respectively.Two subsets strongly related to the specific index form a new subspace related to the specific index.Then,a hybrid monitoring strategy based on predicted specific index using partial least squares(PLS)and T2statistics-based method is proposed for specific index-related process monitoring using comprehensive information.Predicted specific index reflects real-time information for the specific index.T2statistics are used to monitor specific index-related information.Finally,the proposed method is applied to Tennessee Eastman(TE).The results indicate the effectiveness of the proposed method.

Dynamic monitoring of serum liver function indexes in patients with COVID-19

BACKGROUND Some patients with the novel 2019 coronavirus disease(COVID-19)display elevated liver enzymes.Some antiviral drugs that can be used against COVID-19 are associated with a risk of hepatotoxicity.AIM To analyze the clinical significance of the dynamic monitoring of the liver function of patients with COVID-19.METHODS This was a retrospective study of patients diagnosed with COVID-19 in January and February 2020 at the Department of Infection,Shantou Central Hospital.The exclusion criteria for all patients were:(1)History of chronic liver disease;(2)History of kidney disease;(3)History of coronary heart disease;(4)History of malignancy;or(5)History of diabetes.The serum levels of alanine aminotransferase(ALT),aspartate aminotransferase(AST),γ-glutamyltransferase,and total bilirubin of patients with COVID-19 were measured on days 1,3,7 and 14 after admission,and compared to non-COVID-19 patents.RESULTS Twelve patients with COVID-19(seven men and five women)and twelve controls(eight men and four women)were included.There were one,two,and nine patients with severe,mild,and moderate COVID-19,respectively.There were no differences in age and sex between the two groups(both P>0.05).No significant differences were found in albumin,ALT,AST,γ-glutamyltransferase,or total bilirubin between the controls and the patients with COVID-19 on day 1 of hospitalization(all P>0.05).Serum albumin showed a decreasing trend from days 0 to 7 of hospitalization,reaching the lowest level on day 7.Total bilirubin was higher on day 3 than on day 7.ALT,AST,andγ-glutamyltransferase did not change significantly over time.The severe patient was observed to have ALT levels of 67 U/L and AST levels of 75 U/L on day 7,ALT of 71 U/L and AST of 35 U/L on day 14,and ALT of 210 U/L and AST of 123 U/L on day 21.CONCLUSION Changes in serum liver function indicators are not obvious in the early stage of COVID-19,but clinically significant changes might be observed in severe COVID-19.

The Design and Study on CEO Financial Monitoring Index System Based on Stakeholder Theory

This paper summarizes the current financial monitoring theory and the design of index system, analyzes the possible monitoring indexes relative to stakeholders to achieve their own interests, and then categorizes these indexes into five aspects： the finance, the customer, the process, the employee and the society. After a deep analysis of these indexes, we use the Analytic Hierarchy Process to conform the weight of every index, subsequently build up an effective financial monitoring index system.

Evaluation of entropy for monitoring the depth of anesthesia ：ompared with bispectral index： a multicenter clinical trial

Background As a new electroencephalogram （EEG） signal processing technique for monitoring the depth of anesthesia, entropy consists of two indices： reaction entropy （RE） and state entropy （SE）. Our study compared entropy with classical bispectral index （BIS） in reduction of myoelectrical interference and noxious stimuli with EEG signals. Methods Two hundred and eighty patients （ASA I-II, 18-60 years old） undergoing scheduled surgeries from seven medical centers were enrolled. Anesthesia induction was managed with propofol via the target-controlled infusion （TCI） system. The results of BIS, RE, SE, mean arterial pressure （MAP） and heart rate （HR） were recorded before anesthesia induction, at the moment of unconsciousness, before and 2 minutes after administration of muscle relaxant, and before and one and three minutes after the tracheal intubation. Results The values of half maximum effective concentrations （EC50）, 5% effective concentrations （EC05） and 95% effective concentrations （EC95） of propofol effect-site concentration at the onset of unconsciousness were 1.2 （1.1-1.3 μg/ml）, 2.5 （2.4-2.5 μg/ml） and 3.7 （3.7-3.8 μg/ml）, while those of the predicted plasma propofol concentration were 2.8 （2.7-2.9 μg/ml）, 3.9 （3.8-3.9 μg/ml） and 4.9 （4.8-5.0μg/ml）, respectively. The values of BIS, SE and RE were 62, 59 and 63 when 50% of patients lost consciousness, and 79, 80, 85 and 42, 37, 44, respectively, when 5% and 95% of patients were unconscious. The values of BIS, RE and SE dropped two minutes after the injection of muscle relaxant, but there were no significant differences between RE and SE. MAP and HR increased visibly, which indicated a reaction to tracheal intubation; the values of BIS, RE and SE, however, did not display any significant changes. Conclusions This large-sample multicentric study confirmed the values of RE and SE as approximating BIS value, at the onset of unconsciousness during propofol TCI anesthesia. After elimination of myoelectrical activation, all values of RE, SE and BIS decreased significantly and the three indices were less sensitive to noxious stimuli than cardiovascular responses.

Neuroprotective effect of bispectral index-guided fast-track anesthesia using sevoflurane combined with dexmedetomidine for intracranial aneurysm embolization

Dexmedetomidine has sedative, anxiolytic, analgesic, anti-sympathetic, and anti-shivering effects. Dexmedetomidine might be effective in combination with sevoflurane for anesthesia, but prospective randomized controlled clinical trials with which to verify this hypothesis are lacking. In total, 120 patients who underwent embolization of an intracranial aneurysm were recruited from Anhui Provincial Hospital and Renmin Hospital of Wuhan University of China and randomly allocated to two groups. After intraoperative administration of 2% to 3% sevoflurane inhalation, one group of patients received pump-controlled intravenous injection of 1.0 ~tg/kg dexmedetomidine for 15 minutes followed by maintenance with 0.3 ~tg/kg/h until the end of surgery; the other group of patients only underwent pump-controlled infusion of saline. Bispectral index monitoring revealed that dexmedetomidine-assisted anesthesia can shorten the recovery time of spon- taneous breathing, time to eye opening, and time to laryngeal mask removal. Before anesthetic induction and immediately after laryngeal mask airway removal, the glucose and lactate levels were low, the S100~ and neuron-specific enolase levels were low, the perioperative blood pressure and heart rate were stable, and postoperative delirium was minimal. These findings indicate that dexmedetomidine can effectively assist sevoflurane for anesthesia during surgical embolization of intracranial aneurysms, shorten the time to consciousness and extubation, reduce the stress response and energy metabolism, stabilize hemodynamic parameters, and reduce adverse reactions, thereby reducing the damage to the central nervous system. This trial was registered at the Chinese Clinical Trial Registry （http：//www.chictr.org. cn/） （registration number： ChiCTR-IPR- 16008113）.

Comparison of 1.5% lidocaine and 0.5% ropivacaine epidural anesthesia combined with propofol general anesthesia guided by bispectral index

Objective： To compare the effects of epidural anesthesia with 1.5% lidocaine and 0.5% ropivacaine on propofol requirements, the time to loss of consciousness （LOC）, effect-site propofol concentrations, and the hemodynamic variables during induction of general anesthesia guided by bispectral index （BIS） were studied. Methods： Forty-five patients were divided into three groups to receive epidurally administered saline （Group S）, 1.5% （w/w） lidocaine （Group L）, or 0,5% （w/w） ropivacaine （Group R） Propofol infusion was started to produce blood concentration of 4 lag/ml. Once the BIS value reached 40-50, endotracheal intubation was facilitated by 0.1 mg/kg vecuronium. Measurements included the time to LOC, effect-site propofol concentrations, total propofol dose, mean arterial blood pressure （MABP）, and heart rate （HR） at different study time points. Results： During induction of anesthesia, both Groups L and R were similar for the time to LOC, effect-site propofol concentrations, total propofol dose, MABP, HR, and BIS. The total doses of propofol administered until 1 min post-intubation were significantly less in patients of Groups R and L compared with Group S. MABP and HR were significantly lower following propofol induction compared with baseline values in the three groups, or MABP was significantly increased following intubation as compared with that prior to intubation in Group S but not in Groups R and L while HR was significantly increased following intubation in the three groups. Conclusion： Epidural anesthesia with 1.5% lidocaine and 0.5% ropivacaine has similar effects on the time to LOC, effect-site propofol concentrations, total propofol dose, and the hemodynamic variables during induction of general anesthesia.

Efficacy of Bispectral index-monitored closed-loop targeted-controlled infusion of propofol for laparoscopic radical operation for gastric cancer

Objective:To discuss the efficacy of Bispectral index (BIS)-monitored closed-loop targeted-controlled infusion of propofol for laparoscopic radical operation for gastric cancer.Methods:A total of 106 patients with primary gastric cancer who underwent laparoscopic radical operation for gastric cancer in our hospital between August 2015 and February 2018 were chosen as the research subjects and divided into the control group (n=53) and the observation group (n=53) according to the different anesthesia methods. Control group of patients received BIS-monitored manually adjusted targeted-controlled infusion concentration of propofol, and observation group of patients received BIS-monitored closed-loop targeted-controlled infusion of propofol. The differences in hemodynamic index levels as well as serum contents of inflammatory factors and stress hormones were compared between the two groups of patients before anesthesia (T0), 30 min after surgery started (T1) and 30 min before surgery ended (T2).Results:At T0, the differences in hemodynamic index levels as well as serum contents of inflammatory factors and stress hormones were not statistically significant between the two groups. At T1 and T2, hemodynamic indexes MAP and HR levels of observation group were lower than those of control group at the corresponding time points;serum inflammatory factors sICAM-1, IL-1β, IL-8 and TNF-α contents were lower than those of control group at the corresponding time points;serum stress hormones Cor, T4 and glucagon contents were lower than those of control group at the corresponding time points.Conclusion: BIS-monitored closed-loop targeted-controlled infusion of propofol can effectively stabilize the intraoperative hemodynamics and inhibit the systemic inflammatory stress response in patients with laparoscopic radical operation for gastric cancer.

A hybrid algorithm for reengineering the refractive index profile of inhomogeneous coatings from optical in-situ broadband monitoring data

Reengineering the refractive index profile of inhomogeneous coatings is a troublesome task. Multiplicity of solutions may significantly reduced by providing additional information. For this reason an in-situ broadband monitoring system was developed to measure the transmittance of the growing film directly at the rotating substrate. For characterization of these coatings, a new model was developed, which significantly reduces the number of parameters. The refractive index profile may be described by a proper number of equally spaced volume fraction values using the Bruggeman effective media approach. A good initial approximation of the refractive index profile can be generated based on deposition rates for both materials recorded with quartz crystal monitor during manufacturing. During the optimization process, a second order minimization algorithm was used to vary the refractive index profile of the whole coating and film thickness of the intermediate stages. Finally, a significantly improved accuracy of the modelled transmittance was achieved.

Multimode Process Monitoring Based on Fuzzy C-means in Locality Preserving Projection Subspace

For complex industrial processes with multiple operational conditions, it is important to develop effective monitoring algorithms to ensure the safety of production processes. This paper proposes a novel monitoring strategy based on fuzzy C-means. The high dimensional historical data are transferred to a low dimensional subspace spanned by locality preserving projection. Then the scores in the novel subspace are classified into several overlapped clusters, each representing an operational mode. The distance statistics of each cluster are integrated though the membership values into a novel BID (Bayesian inference distance) monitoring index. The efficiency and effectiveness of the proposed method are validated though the Tennessee Eastman benchmark process.

Study on the Evaluation and Monitoring over In-depth Development of Ecotourism

Qualitative indexes contained in the product standards of in-depth ecotourism development are summarized as:carrying capacity control,protection of natural environment,participation of community residents,education about environment protection,enhancing standard management,clean production,green training,and overall monitoring.Based on the model of grey system theory,the improvement of in-depth ecotourism development was predicted,the construction,evaluation and monitoring model for the in-depth development of ecotourism was established,and finally the index system for the evaluation was set as the General Layer(A),the System Layer(B),the Status Layer(C),and the Variable Layer(D).

A remote sensing monitoring method for alpine grasslands desertification in the eastern Qinghai–Tibetan Plateau

Alpine grassland is the typical vegetation in the eastern Qinghai–Tibetan Plateau,which has important ecological service functions,and also supports the development of alpine stock farming.In recent years,under both the natural and human disturbance,alpine grasslands in this area have appeared to different degrees of desertification.A diagnosis of the desertification degree serves as the basis for grassland ecological restoration.This study constructs a comprehensive index based on remote sensing called alpine grassland desertification index(AGDI)to monitor the areas and degree of desertification.The most relevant indicators of desertification,namely,vegetation fraction,aboveground biomass,soil moisture,and land surface temperature,were selected to establish AGDI.The geographical detector is used to reselect and assess these indicators.The results show that the overall verification accuracy of AGDI is 82.05%.In particular,the accuracy of identifying severe desertification is the highest.Our study confirms that the desertification of alpine grasslands in the eastern Qinghai–Tibetan Plateau is characterized by fragmentation.Thus,Landsat-8 OLI data with a spatial resolution of 30 m is more suitable than MODIS data for alpine grasslands desertification monitoring.The research results can provide a methodological reference for monitoring desertification of alpine grasslands and other grassland regions in the world.