This paper proposes the design and development of a novel, portable and low-cost intelligent electronic device (IED) for real-time monitoring of high frequency phenomena in CENELEC PLC band. A high speed floating-poin...This paper proposes the design and development of a novel, portable and low-cost intelligent electronic device (IED) for real-time monitoring of high frequency phenomena in CENELEC PLC band. A high speed floating-point digital signal processor (DSP) along with 4 MSPS analog-to-digital converter (ADC) is used to develop the intelligent electronic device. An optimized algorithm to process the analog signal in real-time and to extract the meaningful result using signal processing techniques has been implemented on the device. A laboratory environment has setup with all the necessary equipment including the development of the load model to evaluate the performance of the IED. Smart meter and concentrator is also connected to the low voltage (LV) network to monitor the PLC communication using the IED. The device has been tested in the laboratory and it has produced very promising results for time domain as well as frequency domain analysis. Those results imply that the IED is fully capable of monitoring high frequency disturbances in CENELEC PLC band.展开更多
Diabetic kidney disease(DKD)is a common complication of diabetes mellitus that contributes to the risk of end-stage kidney disease(ESKD).Wide glycemic var-iations,such as hypoglycemia and hyperglycemia,are broadly fou...Diabetic kidney disease(DKD)is a common complication of diabetes mellitus that contributes to the risk of end-stage kidney disease(ESKD).Wide glycemic var-iations,such as hypoglycemia and hyperglycemia,are broadly found in diabetic patients with DKD and especially ESKD,as a result of impaired renal metabolism.It is essential to monitor glycemia for effective management of DKD.Hemoglobin A1c(HbA1c)has long been considered as the gold standard for monitoring glycemia for>3 months.However,assessment of HbA1c has some bias as it is susceptible to factors such as anemia and liver or kidney dysfunction.Continuous glucose monitoring(CGM)has provided new insights on glycemic assessment and management.CGM directly measures glucose level in interstitial fluid,reports real-time or retrospective glucose concentration,and provides multiple glycemic metrics.It avoids the pitfalls of HbA1c in some contexts,and may serve as a precise alternative to estimation of mean glucose and glycemic variability.Emerging studies have demonstrated the merits of CGM for precise monitoring,which allows fine-tuning of glycemic management in diabetic patients.Therefore,CGM technology has the potential for better glycemic monitoring in DKD patients.More research is needed to explore its application and management in different stages of DKD,including hemodialysis,peritoneal dialysis and kidney transplantation.展开更多
文摘This paper proposes the design and development of a novel, portable and low-cost intelligent electronic device (IED) for real-time monitoring of high frequency phenomena in CENELEC PLC band. A high speed floating-point digital signal processor (DSP) along with 4 MSPS analog-to-digital converter (ADC) is used to develop the intelligent electronic device. An optimized algorithm to process the analog signal in real-time and to extract the meaningful result using signal processing techniques has been implemented on the device. A laboratory environment has setup with all the necessary equipment including the development of the load model to evaluate the performance of the IED. Smart meter and concentrator is also connected to the low voltage (LV) network to monitor the PLC communication using the IED. The device has been tested in the laboratory and it has produced very promising results for time domain as well as frequency domain analysis. Those results imply that the IED is fully capable of monitoring high frequency disturbances in CENELEC PLC band.
基金Supported by Natural Science Foundation of Zhejiang Province,No.LY23H050005and Zhejiang Medical Technology Project,No.2022RC009.
文摘Diabetic kidney disease(DKD)is a common complication of diabetes mellitus that contributes to the risk of end-stage kidney disease(ESKD).Wide glycemic var-iations,such as hypoglycemia and hyperglycemia,are broadly found in diabetic patients with DKD and especially ESKD,as a result of impaired renal metabolism.It is essential to monitor glycemia for effective management of DKD.Hemoglobin A1c(HbA1c)has long been considered as the gold standard for monitoring glycemia for>3 months.However,assessment of HbA1c has some bias as it is susceptible to factors such as anemia and liver or kidney dysfunction.Continuous glucose monitoring(CGM)has provided new insights on glycemic assessment and management.CGM directly measures glucose level in interstitial fluid,reports real-time or retrospective glucose concentration,and provides multiple glycemic metrics.It avoids the pitfalls of HbA1c in some contexts,and may serve as a precise alternative to estimation of mean glucose and glycemic variability.Emerging studies have demonstrated the merits of CGM for precise monitoring,which allows fine-tuning of glycemic management in diabetic patients.Therefore,CGM technology has the potential for better glycemic monitoring in DKD patients.More research is needed to explore its application and management in different stages of DKD,including hemodialysis,peritoneal dialysis and kidney transplantation.