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Multi-physics analysis of permanent magnet tubular linear motors under severe volumetric and thermal constraints 被引量:2
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作者 李方 叶佩青 张辉 《Journal of Central South University》 SCIE EI CAS CSCD 2016年第7期1690-1699,共10页
Permanent magnet tubular linear motors(TLMs) arranged in multiple rows and multiple columns used for a radiotherapy machine were studied. Due to severe volumetric and thermal constraints, the TLMs were at high risk of... Permanent magnet tubular linear motors(TLMs) arranged in multiple rows and multiple columns used for a radiotherapy machine were studied. Due to severe volumetric and thermal constraints, the TLMs were at high risk of overheating. To predict the performance of the TLMs accurately, a multi-physics analysis approach was proposed. Specifically, it considered the coupling effects amongst the electromagnetic and the thermal models of the TLMs, as well as the fluid model of the surrounding air. To reduce computation cost, both the electromagnetic and the thermal models were based on lumped-parameter methods. Only a minimum set of numerical computation(computational fluid dynamics, CFD) was performed to model the complex fluid behavior. With the proposed approach, both steady state and transient state temperature distributions, thermal rating and permissible load can be predicted. The validity of this approach is verified through the experiment. 展开更多
关键词 tubular linear motor multi-physics COUPLING lumped-parameter temperature prediction
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An internal ballistic model of electromagnetic railgun based on PFN coupled with multi-physical field and experimental validation
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作者 Benfeng Gu Haiyuan Li Baoming Li 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第2期254-261,共8页
To accelerate the practicality of electromagnetic railguns,it is necessary to use a combination of threedimensional numerical simulation and experiments to study the mechanism of bore damage.In this paper,a three-dime... To accelerate the practicality of electromagnetic railguns,it is necessary to use a combination of threedimensional numerical simulation and experiments to study the mechanism of bore damage.In this paper,a three-dimensional numerical model of the augmented railgun with four parallel unconventional rails is introduced to simulate the internal ballistic process and realize the multi-physics field coupling calculation of the rail gun,and a test experiment of a medium-caliber electromagnetic launcher powered by pulse formation network(PFN)is carried out.Various test methods such as spectrometer,fiber grating and high-speed camera are used to test several parameters such as muzzle initial velocity,transient magnetic field strength and stress-strain of rail.Combining the simulation results and experimental data,the damage condition of the contact surface is analyzed. 展开更多
关键词 Internal ballistic modeling Electromagnetic rail gun multi-physics field coupling Experimental validation PFN
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Review of Field Weakening Control Strategies of Permanent Magnet Synchronous Motors
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作者 Runze Jing Gaolin Wang +1 位作者 Guoqiang Zhang Dianguo Xu 《CES Transactions on Electrical Machines and Systems》 EI CSCD 2024年第3期319-331,共13页
Due to high power density,high efficiency,and accurate control performance,permanent magnet synchronous motors(PMSMs)have been widely adopted in equipment manufacturing and energy transformation fields.To expand the s... Due to high power density,high efficiency,and accurate control performance,permanent magnet synchronous motors(PMSMs)have been widely adopted in equipment manufacturing and energy transformation fields.To expand the speed range under finite DC-bus voltage,extensive research on field weakening(FW)control strategies has been conducted.This paper summarizes the major FW control strategies of PMSMs,which are categorized into calculation-based methods,voltage closed-loop control methods,and model predictive control related methods.The existing strategies are analyzed and compared according to performance,robustness,and execution difficulty,which can facilitate the implementation of FW control. 展开更多
关键词 Calculation-based methods field weakening control Model predictive control Permanent magnet synchronous motor OVERMODULATION Voltage closed-loop control
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Optimal design of modular dual-field modulated permanent magnet linear motors with thrust characteristics
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作者 MIAO Zhongcui ZHANG Lei +1 位作者 LI Yan ZHANG Hui 《Journal of Measurement Science and Instrumentation》 CAS CSCD 2024年第4期547-557,共11页
To reduce thrust ripple and cost and improve the average thrust of permanent magnet linear motors,a modular dual-field modulation permanent magnet linear motor was studied,and the parameters were optimized.First,sensi... To reduce thrust ripple and cost and improve the average thrust of permanent magnet linear motors,a modular dual-field modulation permanent magnet linear motor was studied,and the parameters were optimized.First,sensitive parameters were selected using the Taguchi method,and then the optimal variables were sampled using the optimal Latin hypercube experimental design method and an ensemble of surrogates model of optimization objectives,and its accuracy was verified.Next,a multi-objective particle swarm optimization algorithm was used to optimize the purpose of“maximum average thrust and minimum thrust ripple”,and the Pareto front of average thrust and thrust ripple was obtained.Finite element analysis showed that the optimized modular dual flux-modulation permanent magnet linear motor(MDFMPMLM)had a 29.5%reduction in thrust ripple and a 5%increase in average thrust compared to the original motor.This study provided an effective method for improving the performance of permanent magnet linear motors. 展开更多
关键词 field modulation thrust characteristics finite element analysis ensemble of surrogates model permanent magnet linear motor multi-objective optimization
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Mathematical Multibody Model of a Soft Mounted Induction Motor Regarding Forced Vibrations Due to Dynamic Rotor Eccentricities Considering Electromagnetic Field Damping 被引量:2
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作者 Ulrich Werner 《Journal of Applied Mathematics and Physics》 2017年第2期346-364,共19页
The paper presents a mathematical multibody model of a soft mounted induction motor with sleeve bearings regarding forced vibrations caused by dynamic rotor eccentricities considering electromagnetic field damping. Th... The paper presents a mathematical multibody model of a soft mounted induction motor with sleeve bearings regarding forced vibrations caused by dynamic rotor eccentricities considering electromagnetic field damping. The multibody model contains the mass of the stator, rotor, shaft journals and bearing housings, the electromagnetic forces with respect of electromagnetic field damping, stiffness and internal (rotating) damping of the rotor, different kinds of dynamic rotor eccentricity, stiffness and damping of the bearing housings and end shields, stiffness and damping of the oil film of the sleeve bearings and stiffness and damping of the foundation. With this multibody model, the bearing housing vibrations and the relative shaft vibrations in the sleeve bearings can be derived. 展开更多
关键词 INDUCTION motor Electromagnetic field DAMPING ROTORDYNAMICS SOFT MOUNTING
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Transient multi-physics behavior of an insert high temperature superconducting no-insulation coil in hybrid superconducting magnets with inductive coupling 被引量:1
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作者 Xiang KANG Yujin TONG +1 位作者 Wei WU Xingzhe WANG 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2023年第2期255-272,共18页
A transient multi-physics model incorporated with an electromagneto-thermomechanical coupling is developed to capture the multi-field behavior of a single-pancake(SP)insert no-insulation(NI)coil in a hybrid magnet dur... A transient multi-physics model incorporated with an electromagneto-thermomechanical coupling is developed to capture the multi-field behavior of a single-pancake(SP)insert no-insulation(NI)coil in a hybrid magnet during the charging and discharging processes.The coupled problem is resolved by means of the finite element method(FEM)for the magneto-thermo-elastic behaviors and the Runge-Kutta method for the transient responses of the electrical circuits of the hybrid superconducting magnet system.The results reveal that the transient multi-physics responses of the insert NI coil primarily depend on the charging/discharging procedure of the hybrid magnet.Moreover,a reverse azimuthal current and a compressive hoop stress are induced in the insert NI coil during the charging process,while a forward azimuthal current and a tensile hoop stress are observed during the discharging process.The induced voltages in the insert NI coil can drive the currents flowing across the radial turns where the contact resistance exists.Therefore,it brings forth significant Joule heat,causing a temperature rise and a uniform distribution of this heat in the coil turns.Accordingly,a thermally/mechanically unstable or quenching event may be encountered when a high operating current is flowing in the insert NI coil.It is numerically predicted that a quick charging will induce a compressive hoop stress which may bring a risk of buckling instability in the coil,while a discharging will not.The simulations provide an insight of hybrid superconducting magnets under transient start-up or shutdown phases which are inevitably encountered in practical applications. 展开更多
关键词 hybrid superconducting magnet high temperature superconducting(HTS)no-insulation(NI)coil inductive coupling multi-physics field thermal stability
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Analysis of the Comprehensive Physical Field for a New Flywheel Energy Storage Motor/Generator on Ships 被引量:1
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作者 Yali Yu Yuanxi Wang +1 位作者 Guosheng Zhang Feng Sun 《Journal of Marine Science and Application》 2012年第1期134-142,共9页
A novel flywheel energy storage (FES) motor/generator (M/G) was proposed for marine systems. The purpose was to improve the power quality of a marine power system (MPS) and strengthen the energy recycle. Two str... A novel flywheel energy storage (FES) motor/generator (M/G) was proposed for marine systems. The purpose was to improve the power quality of a marine power system (MPS) and strengthen the energy recycle. Two structures including the magnetic or non-magnetic inner-rotor were contrasted in the magnetostatic field by using finite element analysis (FEA). By optimally designing the size parameters, the average speed of FEA results of was 17 200 r/m, and the current was controlled between 62 and 68 A in the transient field. The electrical machine electromagnetism design was further optimized by the FEA in the temperature field, to find the local overheating point under the normal operation condition and provide guidance for the cooling system. Finally, it can be concluded from the comprehensive physical field analysis that the novel redundant structure M/G can improve the efficiency of the M/G and maintain the stability of the MPS. 展开更多
关键词 marine power system flywheel energy storage Halbach array magnet structure comprehensivephysical field motor/generator finite element analysis
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A novel fuzzy logic direct torque controller for a permanent magnet synchronous motor with a field programmable gate array 被引量:1
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作者 陈永军 《Journal of Chongqing University》 CAS 2008年第3期228-233,共6页
A high-performance digital servo system built on the platform of a field programmable gate array (FPGA),a fully digitized hardware design scheme of a direct torque control (DTC) and a low speed permanent magnet synchr... A high-performance digital servo system built on the platform of a field programmable gate array (FPGA),a fully digitized hardware design scheme of a direct torque control (DTC) and a low speed permanent magnet synchronous motor (PMSM) is proposed. The DTC strategy of PMSM is described with Verilog hardware description language and is employed on-chip FPGA in accordance with the electronic design automation design methodology. Due to large torque ripples in low speed PMSM,the hysteresis controller in a conventional PMSM DTC was replaced by a fuzzy controller. This FPGA scheme integrates the direct torque controller strategy,the time speed measurement algorithm,the fuzzy regulating technique and the space vector pulse width modulation principle. Experimental results indicate the fuzzy controller can provide a controllable speed at 20 r min-1 and torque at 330 N m with satisfactory dynamic and static performance. Furthermore,the results show that this new control strategy decreases the torque ripple drastically and enhances control performance. 展开更多
关键词 fuzzy control direct torque control field programmable gate array permanent magnet synchronous motor
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Magnetic Field and Operating Performance Analysisof Conical-rotor Permanent Magnet Synchronous Motor 被引量:3
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作者 Jiabao Wang Shoudao Huang +1 位作者 Chao Guo Yaojing Feng 《CES Transactions on Electrical Machines and Systems》 2018年第1期181-187,共7页
In order to accurately analyze the magnetic field of conical-rotor permanent magnet synchronous motor(CR-PMSM),the effectiveness of two methods was studied on handling of problems concerned with non-uniform distributi... In order to accurately analyze the magnetic field of conical-rotor permanent magnet synchronous motor(CR-PMSM),the effectiveness of two methods was studied on handling of problems concerned with non-uniform distribution of magnetic field along axial direction in CR-PMSM,which were sectional calculation(SC)method and three-dimensional finite element(3-D FE)method.On this basis,the influence of the axial displacement and dq-axis currents on the operating characteristics of axial magnetic force and torque is analyzed by using the 3-D FE model.Analysis results show that the axial magnetic force and torque decrease with the increase of axial displacement of the rotor,and the amplitude regularity of the axial magnetic force is affected by the d-axis current.A prototype machine is fabricated and tested,in order to validate the design theory. 展开更多
关键词 Magnetic field of conical-rotor permanent magnet synchronous motor operating characteristics non-uniform of magnetic field 3-D FE method
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Analysis of temperature field for a surface-mounted and interior permanent magnet synchronous motor adopting magnetic-thermal coupling method 被引量:4
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作者 Jikai Si Suzhen Zhao +2 位作者 Haichao Feng Yihua Hu Wenping Cao 《CES Transactions on Electrical Machines and Systems》 2018年第1期166-174,共9页
Aiming at obtaining high power density of surface-mounted and interior permanent magnet synchronous motor(SIPMSM),it is important to accurately calculate the temperature field distribution of SIPMSM,and a magnetic-the... Aiming at obtaining high power density of surface-mounted and interior permanent magnet synchronous motor(SIPMSM),it is important to accurately calculate the temperature field distribution of SIPMSM,and a magnetic-thermal coupling method is proposed.The magnetic-thermal coupling mechanism is analyzed.The thermal network model and finite element model are built by this method,respectively.The effects of power frequency on iron losses and temperature fields are analyzed by the magnetic-thermal coupling finite element model under the condition of rated load,and the relationship between the load and temperature field is researched under the condition of the synchronous speed.In addition,the equivalent thermal network model is used to verify the magnetic-thermal coupling method.Then the temperatures of various nodes are obtained.The results show that there are advantages in both computational efficiency and accuracy for the proposed coupling method,which can be applied to other permanent magnet motors with complex structures. 展开更多
关键词 Equivalent thermal network method magnetic-thermal coupling method power frequency iron loss surface-mounted and interior permanent magnet synchronous motor(SIPMSM) temperature field
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Bifurcations and chaos in indirect field-oriented control of induction motors 被引量:1
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作者 BoZHANG YiminLU ZongyuanMAO 《控制理论与应用(英文版)》 EI 2004年第4期353-357,共5页
Stability of indirect field-oriented control (IFOC) of induction motor drives is greatly influenced by estimated value of rotor time constant. By choosing estimation error of rotor time constant as bifurcation paramet... Stability of indirect field-oriented control (IFOC) of induction motor drives is greatly influenced by estimated value of rotor time constant. By choosing estimation error of rotor time constant as bifurcation parameter, the conditions of generating Hopf bifurcation in IFOC drives are analyzed. Dynamic responses and Lyapunov exponents show that chaos and limit cycles will arise for some ranges of load torque with certain PI speed controller setting. Stable drives are required for conventional applications, but chaotic rotation can promote efficiency or improve dynamic characteristics of drives. Thus, the study may be a guideline for designing a stable system or an oscillating system. 展开更多
关键词 Induction motor Indirect field-oriented control Hopf bifurcation CHAOS
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Development of Magnetic Field Sensor and Motor Fault Monitoring Application
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作者 Ziyuan Tong Zhaoyang Dong +2 位作者 Minming Tong Bo Wang Li Meng 《Journal of Computer and Communications》 2014年第7期42-45,共4页
For the purpose of motor fault real-time monitoring, this research developed a nano-silicon ni- tride film based magnetic field (MF) sensor, and applied this sensor in MF detection of two common faults. Through experi... For the purpose of motor fault real-time monitoring, this research developed a nano-silicon ni- tride film based magnetic field (MF) sensor, and applied this sensor in MF detection of two common faults. Through experiment, it turned out that arc discharge and slot discharge occur in motor fault produce MF with certain laws. This result proved the feasibility of the sensor and sensing method in MF analysis, and revealed possibility of a new method in fault detection. 展开更多
关键词 MAGNETIC field Sensor motor FAULT SLOT DISCHARGE ARC DISCHARGE Real-Time Monitoring
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Torque Ripple Suppression Control Strategy for Brushless Integrated Starter/Generator Wound-Field Synchronous Motor 被引量:2
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作者 骆光照 张围围 +2 位作者 杨南方 马鹏 刘卫国 《Defence Technology(防务技术)》 SCIE EI CAS 2012年第3期154-160,共7页
A flux linkage compensation field oriented control (FOC) method was proposed to suppress the speed and torque ripples of a brushless wound-field synchronous motor in its starting process. The starting process was anal... A flux linkage compensation field oriented control (FOC) method was proposed to suppress the speed and torque ripples of a brushless wound-field synchronous motor in its starting process. The starting process was analyzed and the model of wound-field synchronous electric machine was established. The change of field current of the electric machine was described mathematically for simplified exciter and rotate rectifier. Based on the traditional field control, the flux linkage compensation was introduced in d-axis current to counteract the flux ripple. Some simulation and preliminary experiments were implemented. The results show that the proposed method is feasible and effective. 展开更多
关键词 electrical engineering brushless ISG wound-field synchronous motor torque ripple suppression flux linkage compensation starting control
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Field Weakening Control of a Separately Excited DC Motor Using Neural Network Optemized by Social Spider Algorithm
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作者 Waleed I. Hameed Ahmed S. Kadhim Ali Abdullah K. Al-Thuwaynee 《Engineering(科研)》 2016年第1期1-10,共10页
This paper presents the speed control of a separately excited DC motor using Neural Network (NN) controller in field weakening region. In armature control, speed controller has been used in outer loop while current co... This paper presents the speed control of a separately excited DC motor using Neural Network (NN) controller in field weakening region. In armature control, speed controller has been used in outer loop while current controller in inner loop is used. The function of NN is to predict the field current that realizes the field weakening to drive the motor over rated speed. The parameters of NN are optimized by the Social Spider Optimization (SSO) algorithm. The system has been implemented using MATLAB/SIMULINK software. The simulation results show that the proposed method gives a good performance and is feasible to be applied instead of others conventional combined control methods. 展开更多
关键词 DC motor Drive field Weakening Neural Network Social Spider Optimization
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Coupled Numerical Simulation of Electromagnetic and Flow Fields in a Magnetohydrodynamic Induction Pump
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作者 He Wang Ying He 《Fluid Dynamics & Materials Processing》 EI 2024年第4期889-899,共11页
Magnetohydrodynamic(MHD)induction pumps are contactless pumps able to withstand harsh environments.The rate of fluid flow through the pump directly affects the efficiency and stability of the device.To explore the inf... Magnetohydrodynamic(MHD)induction pumps are contactless pumps able to withstand harsh environments.The rate of fluid flow through the pump directly affects the efficiency and stability of the device.To explore the influence of induction pump settings on the related delivery speed,in this study,a numerical model for coupled electromagnetic and flow field effects is introduced and used to simulate liquid metal lithium flow in the induction pump.The effects of current intensity,frequency,coil turns and coil winding size on the velocity of the working fluid are analyzed.It is shown that the first three parameters have a significant impact,while changes in the coil turns have a negligible influence.The maximum increase in working fluid velocity within the pump for the parameter combination investigated in this paper is approximately 618%.As the frequency is increased from 20 to 60 Hz,the maximum increase in the mean flow rate of the working fluid is approximately 241%.These research findings are intended to support the design and optimization of these devices. 展开更多
关键词 Magnetic fluid multi-physical field coupling induction pump numerical simulation liquid metal conveying
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Research on heat dissipation characteristics of magnetic fluid bearings under multiple field coupling effects
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作者 CHEN Liwen WU Weiying +2 位作者 GAO Dianrong ZHAO Jianhua CUI Bingyan 《High Technology Letters》 EI CAS 2024年第3期263-270,共8页
This paper analyzes the sources of heat losses in magnetic fluid bearings,proposes various cou-pling relationships of physical fields,divides the coupled heat transfer surfaces while ensuring the continuity of heat fl... This paper analyzes the sources of heat losses in magnetic fluid bearings,proposes various cou-pling relationships of physical fields,divides the coupled heat transfer surfaces while ensuring the continuity of heat flux density,and analyzes the overall heat dissipation pathways of the bearings.By changing parameters such as input current,rotor speed,and inlet oil flow rate,the study applies a multi-physics field coupling method to investigate the influence of different parameters on the temper-ature field and heat dissipation patterns of the bearings,which is then validated through experi-ments.This research provides a theoretical basis for the optimal design of magnetic fluid bearing sys-tems. 展开更多
关键词 magnetic fluid bearing multi-physics field coupling multiple parameter varia-tion heat dissipation pattern
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Cooling and Optimization in the Groove of the Outer Rotor HubMotor
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作者 Zhuo Liu Yecui Yan 《Frontiers in Heat and Mass Transfer》 EI 2024年第5期1443-1460,共18页
The external rotor hub motor adopts direct drive mode,no deceleration drive device,and has a compact structure.Its axial size is smaller than that of a deceleration-driven hub motor,which greatly reduces the weight of... The external rotor hub motor adopts direct drive mode,no deceleration drive device,and has a compact structure.Its axial size is smaller than that of a deceleration-driven hub motor,which greatly reduces the weight of the vehicle and increases the cruising range of the vehicle.Because of the limited special working environment and performance requirements,the hub motor has a small internal space and a large heat generation,so it puts forward higher requirements for heat dissipation capacity.For the external rotor hub motor,a new type of in-tank watercooled structure of hub motor was proposed to improve its cooling effect and performance.Firstly,the threedimensional finite element model of the motor is established to analyze the characteristics of motor loss and temperature field distribution.Secondly,the cooling performance of different cooling structures in the tank was studied.Finally,the thermal network model and three-dimensional finite element analysis were used to optimize the water-cooled structure in the tank,and the power density of themotor was improved by improving the cooling performance under the condition of volume limitation of the hub motor.The results show that the cooling effect of the proposed water-cooled structure in the tank is significant under the condition of constant power density.Compared to natural ventilation,the maximum temperature was reduced by 33.13°C and the cooling effect was increased by about 27.7%. 展开更多
关键词 Outer rotor hub motor temperature field water cooling in the tank motor loss thermal networks high torque density
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AN ANALYSIS OF AXISYMMETRIC MAGNETIC FIELD OF LINEAR OSCILLATION MOTOR
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作者 汪玉凤 臧小杰 和乔 《Journal of Coal Science & Engineering(China)》 2000年第2期75-77,共3页
In this paper, using axial field finite analysis method, the field of a movable core type linear oscillation motor is analyzed. The program of axial field finite analysis is worked out. Using this program, we analyze ... In this paper, using axial field finite analysis method, the field of a movable core type linear oscillation motor is analyzed. The program of axial field finite analysis is worked out. Using this program, we analyze various fields, including the field excited by permanent magnet materials, the field by two coils respectively, and the fields with the core moving to various positions. 展开更多
关键词 axial field finite analysis method electric machines linear oscillation motor permanent magnet
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Cortico-striatal gamma oscillations are modulated by dopamine D3 receptors in dyskinetic rats
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作者 Pengfei Wang Yuewei Bi +6 位作者 Min Li Jiazhi Chen Zhuyong Wang Huantao Wen Ming Zhou Minjie Luo Wangming Zhang 《Neural Regeneration Research》 SCIE CAS 2025年第4期1164-1177,共14页
Long-term levodopa administration can lead to the development of levodopa-induced dyskinesia.Gamma oscillations are a widely recognized hallmark of abnormal neural electrical activity in levodopa-induced dyskinesia.Cu... Long-term levodopa administration can lead to the development of levodopa-induced dyskinesia.Gamma oscillations are a widely recognized hallmark of abnormal neural electrical activity in levodopa-induced dyskinesia.Currently,studies have reported increased oscillation power in cases of levodopa-induced dyskinesia.However,little is known about how the other electrophysiological parameters of gamma oscillations are altered in levodopa-induced dyskinesia.Furthermore,the role of the dopamine D3 receptor,which is implicated in levodopa-induced dyskinesia,in movement disorder-related changes in neural oscillations is unclear.We found that the cortico-striatal functional connectivity of beta oscillations was enhanced in a model of Parkinson’s disease.Furthermore,levodopa application enhanced cortical gamma oscillations in cortico-striatal projections and cortical gamma aperiodic components,as well as bidirectional primary motor cortex(M1)↔dorsolateral striatum gamma flow.Administration of PD128907(a selective dopamine D3 receptor agonist)induced dyskinesia and excessive gamma oscillations with a bidirectional M1↔dorsolateral striatum flow.However,administration of PG01037(a selective dopamine D3 receptor antagonist)attenuated dyskinesia,suppressed gamma oscillations and cortical gamma aperiodic components,and decreased gamma causality in the M1→dorsolateral striatum direction.These findings suggest that the dopamine D3 receptor plays a role in dyskinesia-related oscillatory activity,and that it has potential as a therapeutic target for levodopa-induced dyskinesia. 展开更多
关键词 aperiodic components dopamine D3 receptor dorsolateral striatum functional connectivity gamma oscillations levodopa-induced-dyskinesia local field potentials NEUROMODULATION Parkinson’s disease primary motor cortex
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Early electrical field stimulation prevents the loss of spinal cord anterior horn motoneurons and muscle atrophy following spinal cord injury 被引量:10
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作者 Cheng Zhang Wei Rong +3 位作者 Guang-Hao Zhang Ai-Hua Wang Chang-Zhe Wu Xiao-Lin Huo 《Neural Regeneration Research》 SCIE CAS CSCD 2018年第5期869-876,共8页
Our previous study revealed that early application of electrical field stimulation(EFS) with the anode at the lesion and the cathode distal to the lesion reduced injury potential, inhibited secondary injury and was ... Our previous study revealed that early application of electrical field stimulation(EFS) with the anode at the lesion and the cathode distal to the lesion reduced injury potential, inhibited secondary injury and was neuroprotective in the dorsal corticospinal tract after spinal cord injury(SCI). The objective of this study was to further evaluate the effect of EFS on protection of anterior horn motoneurons and their target musculature after SCI and its mechanism. Rats were randomized into three equal groups. The EFS group received EFS for 30 minutes immediately after injury at T_(10). SCI group rats were only subjected to SCI and sham group rats were only subjected to laminectomy. Luxol fast blue staining demonstrated that spinal cord tissue in the injury center was better protected; cross-sectional area and perimeter of injured tissue were significantly smaller in the EFS group than in the SCI group. Immunofluorescence and transmission electron microscopy showed that the number of spinal cord anterior horn motoneurons was greater and the number of abnormal neurons reduced in the EFS group compared with the SCI group. Wet weight and cross-sectional area of vastus lateralis muscles were smaller in the SCI group to in the sham group. However, EFS improved muscle atrophy and behavioral examination showed that EFS significantly increased the angle in the inclined plane test and Tarlov's motor grading score. The above results confirm that early EFS can effectively impede spinal cord anterior horn motoneuron loss, promote motor function recovery and reduce muscle atrophy in rats after SCI. 展开更多
关键词 nerve regeneration spinal cord injury electrical field stimulation anterior horn MOTONEURONS vastus lateralis muscle Tarlov's motor grading scale inclined plane test choline acetyltransferase transmission electron microscopy neural regeneration
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