Analysis of the Effectiveness of Clopidogrel Combined with Aspirin in the Treatment of Coronary Heart Disease in Community-Dwelling Elderly

Objective:To analyze the combined therapeutic effect of clopidogrel(CLO)and aspirin(ASP)on coronary heart disease(CHD)in community-dwelling elderly.Methods:Thirty elderly patients with CHD who were admitted to the Xinxin Community Health Service Station,Pangzhuang Street,Quanshan District,Xuzhou City,from November 2020 to November 2022 were selected and randomly grouped into an observation group and a control group,with 15 cases in each group.The observation group was given the combination of CLO and ASP and the reference group was given only ASP.The total effective rate and other treatment indicators between the two groups were compared.Results:The total effective rate of the observation group(93.33%)was higher than that of the reference group(60.00%)(P<0.05).The adverse drug reaction rate(13.33%)and long-term cardiovascular adverse event rate(6.67%)of the observation group were lower than those of the reference group at 46.67%and 40.00%respectively,(P<0.05).Before treatment,the two groups had no difference in the quality-of-life scores(P>0.05).After treatment,the quality-of-life scores of the observation group were higher than those of the reference group(P<0.05).Conclusion:CLO combined with ASP improved the therapeutic effect of community-dwelling elderly patients with CHD,reduced adverse reactions during medication,prevented adverse cardiovascular events,and comprehensively improved the patient’s quality of life.

Study on the Layout of 15-Minute Community-Life Circle in Third-Tier Cities Based on POI: Baoding City of Hebei Province

At present, the planning of 15-minute community-life circle is being actively promoted in China. Taking Baoding City as an example, the status quo of service facilities layout was analyzed based on the POI data. Using the spatial accessibility algorithm, the ranges of 15-minute life circle of more than 1000 communities in Baoding were determined. By calculating the up-to-standard rates of public service facilities in each district, it is found that the allocation of medical facilities and commercial facilities in urban community life circle is relatively perfect, but the allocation of public cultural facilities and pension facilities is obviously inadequate. Based on this, optimization suggestions on the layout of public service facilities in the 15-minute life circle were put forward from three aspects: facilities sharing, function mixing and population structure and activity characteristics differentiation. It not only provides data and technical support for the planning and construction of community life circle in Baoding city, but also provides referable examples and promotable models for the community planning of third-tier cities.

Delineation of an Urban Community Life Circle Based on a Machine-Learning Estimation of Spatiotemporal Behavioral Demand

Delineating life circles is an essential prerequisite for urban community life circle planning. Recent studies combined the environmental contexts with residents’ global positioning system(GPS) data to delineate the life circles. This method, however, is constrained by GPS data, and it can only be applied in the GPS surveyed communities. To address this limitation, this study developed a generalizable delineation method without the constraint of behavioral data. According to previous research, the community life circle consists of the walking-accessible range and internal structure. The core task to develop the generalizable method was to estimate the spatiotemporal behavioral demand for each plot of land to acquire the internal structure of the life circle, as the range can be delineated primarily based on environmental data. Therefore, behavioral demand estimation models were established through logistic regression and machine learning techniques, including decision trees and ensemble learning. The model with the lowest error rate was chosen as the final estimation model for each type of land. Finally, we used a community without GPS data as an example to demonstrate the effectiveness of the estimation models and delineation method. This article extends the existing literature by introducing spatiotemporal behavioral demand estimation models, which learn the relationships between environmental contexts, population composition and the existing delineated results based on GPS data to delineate the internal structure of the community life circle without employing behavioral data. Furthermore, the proposed method and delineation results also contributes to facilities adjustments and location selections in life circle planning, people-oriented transformation in urban planning, and activity space estimation of the population in evaluating and improving the urban policies.

Roles of mutual help of local community networks in community health activities: Improvement for the quality of life of older people in Thailand

Objectives: This study aimed to describe work and activities of community networks focusing on the improvement of the quality of life (QOL) of older people in Thailand.The understanding of the work can help enhancing the community development and strengthening of local communities and their networks.Methods: Qualitative methods including in-depth interview,observation,and focus group discussion were employed to the study.64 participants participated to the study and were recruited from 4 key actors within the community.Content analysis was used to analyze the obtained data.This study was conducted in 6 local administrative organizations (LAOs) which selected from the outstanding areas of the project.Each LAO represents one sub-district of the regions of Thailand namely;(1) the upper north,(2) the lower north,(3)the upper eastern,(4) the lower eastern,(5) the central and (6) the south.Results: The findings of this study were categorized into three main themes: (1) Social capital including people in the community,social groups,and organizations,(2) Mutual help/collaboration activities composed of six sets of activities related to social capitals working on the improvement of QOL of older people,and (3) Impacts of the mutual help/collaboration activities on older people and local communities who help to improve of QOL of older people.Conclusion: The findings are important features for the community development.These themes should be recommended for community nurses,health related groups and organizations for the improvement of QOL of older people in the community.

Age-trends in Cognitive Function and Quality of Life: Sex Differences in a Community Population in Taiwan region,China

Population aging has developed into a significant area of concern in developed countries, especially in relation to thepreservation of functional independence and the quality of life (QoL). However, information on the contribution ofsex differences in quality of life and cognitive function is scarce. Therefore, this study aimed to investigate potentialdifferences in cognitive function and QoL between males and females. For this study, we recruited 382 healthy subjectsaged 19–79 years from communities in Southern Taiwan region,China. Cognitive function and QoL were assessed using the UCSD Performance-based Skills Assessment, Brief Version (UPSA-B) and World Health Organization Quality ofLife Instruments (WHOQOL-BREF), respectively. The effects of sex, age groups, and interaction of sex and ageon the UPSA-B and WHOQOL-BREF scores were examined. We found that the financial and communicationdomains of the UPSA-B showed declining trends with age in both sexes, although these trends were more obviousin females than in males. In the domain of Physical Capacity, QoL showed an age-increased trend in males, whileQoL in the Environment domain showed an age-increased trend in females. Regarding the relationships betweencognitive function and QoL, we found that the financial skill and communication skill of UPSA-B was positivelycorrelated to the psychological well-being domain of WHOQOL-BREF, in males of age <40 years. In conclusion,our findings demonstrate differential relationships between cognitive function and QoL between males and females,which could serve as a basis for further study between cognitive function and quality of life in communities.

Study on the quality of life and its related factors for older adults in communities in Beijing,China

Objectives:To describe the quality of life(QOL)of adults≥60 years of age in communities in Beijing and explore demographic,clinical,and psychological factors associated with QOL.Methods:This was a cross-sectional study.A total of 363 older adults were recruited,in which 313 completed the questionnaires.Depressive symptoms were measured with the Self-Rating Depression Scale(SDS)and QOL was analyzed with the 36-item short form(SF-36).The t-test and Mann-Whitney U tests were used to compare QOL by gender and age group.Factors associated with QOL were determined using multiple linear regression.Results:Among 313 older adults,depressive symptoms were observed to be prevalent to the extent of 16.6%.Overall,participants had higher QOL in the domains of social role functioning and emotional role functioning,with lower QOL in the domains of physical functioning and general health perceptions.There were no significant differences in QOL between women and men.However,there were significant differences between different age groups,with older adults having better mental QOL than younger adults.Better physical QOL was associated with less depressive symptoms,having a partner,and younger age(R2=28.7%).Better mental QOL was associated with less depressive symptoms,less chronic disease,and older age(R^(2)=34.7%).Conclusions:With aging,physical QOL was lower and mental QOL was better.Less depressive symptoms,having a spouse or partner,and young-old age assert positive influence on physical QOL of the older adults;and less depressive symptoms,no chronic disease,and older age assert positive influence on mental QOL.

Is Cognition a Determinant of Health Related Quality of Life in Community Dwelling Non Demented Elderly?

Quality of life (QOL) is an important topic in social and medical sciences, it has a multidimensional nature and is influenced by many factors. Aim of the Work: In this study we want to assess the impact of cognitive impairment on the health related quality of life (HR-QOL) of community dwelling non demented elderly. Subject and Method: 115 non demented elderly, 60 years and older recruited from outpatient geriatric clinic at Al Mansoura General Hospital, Dakahlia, Egypt. Each participant underwent, comprehensive geriatric assessment, assessing cognitive function using the mini-mental state examination (MMSE) and montreal cognitive function test, assessing the health related quality of life (HR-QOL) by the RAND-36 health survey. Results: We found that the elderly with impaired cognition by both MMSE and Montreal test were significantly older;the ones with lower education, with more depressive symptoms, had more functional impairment and had lower HR-QOL scores than the elderly with normal cognitive function, after controlling for confounders still cognition was a determinant of HR-QOL. Also by linear correlation coefficient a significant correlation between HR-QOL and age, function, cognition and depression was found. Conclusion: Cognition affects significantly HR-QOL of the elderly, so we can say that interventions targeting cognition in the elderly can significantly improve their QOL.

Research Progress on the Influence of Movement Instruction on Community Life in Patients with Coronary Heart Disease

The incidence of coronary heart disease increases year by year with the material level of our country.It has a harmful effect on the patient’s life health and quality of life.Movement Instruction is an important aspect of the secondary prevention project of cardiac rehabilitation in patients with coronary heart disease.Although it has a history of decades at inland and abroad,the present situation in China is not optimistic.Some studies have shown that the popularization and participation of cardiac rehabilitation is true and lacking.This paper sums up the relevant knowledge of coronary heart disease,coronary heart disease movement instruction and its impact on community life of patients at home and abroad,and reviews the research results of movement instruction on community rehabilitation of coronary heart disease in recent years,which provides a theoretical reference and prospect for the future research of community exercise rehabilitation of coronary heart disease.

Happy Life at the Foot of the Imperial City Wall——A Glimpse of Community Life in Dongcheng District, Beijing

Grandpa Qin, now 74, has returned to where he had lived for more than six decades in the company of his daughter. In front of him, the old dilapidated scenes have all disappeared. The former nine 1.9-meter-wide lanes have become 12 six-meter-wide roads. The former crowded courtyards, 11 stairs down the lanes, have completely changed their outlook. The only things that seem to have not changed are the old Beijing style of blue tiles and gray bricks and the imperial city walls nearby that are the witnesses to all these changes. Grandpa Qin is among the 300 households who have returned after the rebuilding project was completed. Qin’s family lived in the Nanchizi community for five generations. The big

Host plant traits play a crucial role in shaping the composition of epiphytic microbiota in the arid desert,Northwest China

Phyllosphere microorganisms are a crucial component of environmental microorganisms,highly influenced by host characteristics,and play a significant role in plant health and productivity.Nonetheless,the impact of host characteristics on shaping phyllosphere microbial communities of plants with different life forms remains ambiguous.Utilizing high-throughput sequencing technology,this study analyzed the diversity and community composition of phyllosphere epiphytic microorganisms(e.g.,bacteria and fungi)of various plant life forms in the hinterland of the Gurbantunggut Desert,Northwest China.Functional annotation of prokaryotic taxa(FAPROTAX)and fungi function guild(FUNGuild)were employed to assess the ecological functions of microorganisms and to investigate the role of stochastic and deterministic processes in shaping phyllosphere microbial communities.Result showed a diverse array of phyllosphere epiphytic microorganisms in the desert plants,with Proteobacteria,Cyanobacteria,and Actinobacteriota dominating bacterial community,while Ascomycota and Basidiomycota were prevalent in fungal community.Comparison across different plant life forms highlighted distinct microbial communities,indicating strong filtering effects by plant characteristics.FAPROTAX prediction identified intracellular parasites(accounting for 27.44%of bacterial community abundance),chemoheterotrophy(10.12%),and phototrophy(17.41%)as the main functions of epiphytic bacteria on leaves of different life form plants.FUNGuild prediction indicated that phyllosphere epiphytic fungi primarily served as Saprotrophs(81.77%),Pathotrophs(17.41%),and Symbiotrophs(0.82%).Co-occurrence network analysis demonstrated a predominance of positive correlations among different microbial taxa.Raup-Crick dissimilarity index analysis revealed that deterministic processes predominantly influenced phyllosphere bacterial and fungal community assembly.Variance partitioning analysis and random forest modeling suggested that plant leaf functional traits significantly impacted both bacterial and fungal community composition,with fungal community composition showing a closer association with leaf nutrients and physiology compared with bacterial community composition.The distinct responses of bacterial and fungal communities to plant traits were attributed to the differing properties of bacteria and fungi,such as bacteria having higher potential dispersal rates and broader ecological niches than fungi.Overall,the results indicate that phyllosphere bacterial and fungal communities undergo similar community assembly processes,with fungi being more influenced by plant characteristics than bacteria.These findings offer novel insights into the ecology of phyllosphere microbial communities of desert plants.

Sustaining Increase in Life Expectancy in Africa Requires Active Preventive Measures against Non-Communicable Diseases

It is projected that aged population (≥60 years) will continue to increase globally, including in Africa. This is due to reduced population growth, decreased fecundity and improved medical interventions;factors which increase life expectancy. While this is typical for developed countries, it is not the same for Africa and similar developing regions. In these regions, a significant proportion of death is due to non-communicable diseases (NCD’s) such as hypertension, cerebrovascular accident, coronary heart disease, diabetes mellitus, chronic renal disease and cancer, among others. Rising prevalence of NCD’s due mainly to western style diets and sedentary living is made worse by inadequate nutrition education, high prevalence of low birth weight, poor health services, lack of efficient tobacco control and deficient planning of built environment. In order to halt the possible reduction in life expectancy occasioned by NCD’s, efforts by the community, health planners and governments in Africa to address relevant NCD’s, must be put in place. Suggested measures are: nutrition education, regular community directed physical exercise, improved environmental planning and development. Others are review of present health service model, early detection, prevention and treatment of NCD’s, including improved antenatal care to reduce low birth weights, and establishment of policies and measures that decreased access to tobacco especially by women of childbearing age. Africa and similar developing regions cannot fund the health bill due to NCD’s and their complications;hence it is important that this scourge is attended to with all seriousness.

Effect of Tourism Activities on Coral Communities at the Gulf of Suez, Red Sea

Although the rapidly expanding tourism industry is considered an extremely important economic activity, it caused increasing pressure on coral reefs of Egypt. Damage occurs from both direct and indirect impacts of tourism activities on coral communities. The Gulf of Suez has increasing of resorts from 8 at 2000 to 31 at 2014. This affected the coral communities along the area of study leads to a decrease in coral areas from 960 m2 at 2000 to 750 m2 at 2014, number of coral species from 21 species at 2000 to only 14 species at 2014, percentage cover of life coral from 46.4% at 2000 to 10.6% at 2014;on contrary, dead coral increased from 23.8% to 47.9% at the same period. This accompanied with an increase in the percentage of the algal cover from 8.6% at 2000 to 19.4% at 2014. The statistical analysis revealed a high correlation between the increased tourism activities and the coral status variables measured during the study. The data obtained showed high significant positive and negative correlation between the different variables that determined according to the effect of the different variables on each other and the relation between them. The simple linear regression statistical analyses showed a significant effect of tourism activities on the coral status, the analyses indicated that each increase in number of resorts by one resort leads to significant decrease in total coral area at the site by 0.9%, the analysis also showed that 80% of that decrease referred to the effect of tourism activities and 20% referred to other reasons. The analysis of variance (ANOVA) divided the recoded coral species into three categories, the first is soft corals which recorded significant increase in percentage cover from 2000 to 2014, the second is three species that recorded insignificant difference during the period of study, while the third category include most of the recorded species and they showed significant decrease in their percentage cover along time of study. The data obtained illustrated that all the investigated coral parameters are affected by the increasing tourism activities.

The Ideal Directions for the Advancement of Building an Ecological Civilization in the New Era: From Creating a Better Life for the Chinese People to Global Ecological Governance

According to the report to the 19th CPC National Congress, socialism with Chinese characteristics entered a new era with the specified strategical task of building China into a great modern socialist country that is prosperous, strong, democratic, culturally advanced, harmonious and beautiful. The report also stressed that building an ecological civilization is vital to sustaining the Chinese nation's development. Against such a backdrop, it is necessary to analyze the "building of an ecological civilization" from three directions, i.e. satisfying people's requirement for a better life, fulfilling the goal of the Beautiful China Initiative and taking the lead in global ecological governance. This is an inevitable requirement for the advancement of the harmonious coexistence between man and nature and at the same time corresponds to the internal demand for the implementation of Xi Jinping Thought on Socialism with Chinese Characteristics for a New Era.

Disability and Quality of Life among Elderly Persons with Self-Reported Hearing Impairment: Report from the Ibadan Study of Aging

Background: Despite a high prevalence of hearing impairment (HI) among the elderly, the effect on their quality of life (QOL) has not been well studied in this environment. Aim: To determine the prevalence of disability and profile of QOL among elderly persons (aged ≥65 years) with HI. Design of Study: Cross-sectional. Setting: Eight contiguousYoruba-speaking states in Nigeria. Methods: Face-to-face interviews of respondents selected using a multi-stage, stratified area probability sampling of households;HI was based on self report and observer confirmation and the QOL was measured with the World Health Organization brief version (WHOQOL-Bref). Results: The prevalence of disability in Activities of Daily Living (ADL) was 35.4% while it was 10.1% in Instrumental ADL. Prevalence increased significantly with increasing age (P = 0.05). Disability in ADL (P = 0.01), poor family interaction (P = 0.01), poor community involvement (P = 0.01) cognitive impairment (P = 0.05) and poor report of overall health (P = 0.05) were significantly more common among the elderly with HI than those without. No significant differences were found in regard to current depression or the likelihood of experiencing verbal, physical or emotional abuses. Logistic regression analyses adjusting for age, sex, chronic medical conditions and disability confirmed the salient effect of HI on the decrement in the physical domains (P = 0.05). Conclusion: HI is associated with high prevalence of disability and has adverse effect on the quality of life. This observation strengthens the need for hearing rehabilitation in the policy formulation on the care of the elderly in resource-poor settings.

Human Care Theory and Influences on the Life Quality Index of Cancer Patients in Household Life

To investigatetheinfluences of the application of human care theory on the life quality and happiness of cancer patients after they receiveda community nursing care which was implemented by the human care theory. The quality life and the happiness index of 93 patients with cancer living in the six communities in Jillin were assessed, the assessment of the life quality was based on a life quality scale (SF-36) and that of the happiness index was based on Memorial University of Newfoundland Scale of Happiness (MUNSH). The community nurses cared for these patients by applying the theory of human care and the life quality and the happiness index of the patients were observed after the care. The results showed that there were significant differences in the score of 5 dimensions in the eight dimensions of the life quality between before the care and after the care (<0.05), and there were significant differences in the average sores of the positive emotion, positive experience, negative emotion, negative experience and level of happiness included in the happiness index between before the care and after the care (<0.05), suggesting that the theory of human care can be used for the care of patients with cancer and the application of the theory can effectively improve the life quality and the happiness index of the patients, strengthen their problem-solving abilities and let them have a positive attitude towards their lives.

On the Right to Life

The COVID-19 pandemic is not only the first public health emergency that human beings are jointly faced with, but also the first time that mankind is confronted with a tremendous disaster together To face lives rationally in a pandemic, "criteria" and "rules" need to be regulated by reason Amid such a catastrophe, we need to reply to questions such as whether the right to life should take precedence over other rights and whether each individual’s life should be treated equally, the answers to which, of course, are definitely positive With the advent of a risk society, public health emergencies are no longer occasional incidents Instead, they might become a more frequent problem in the development of modernity In the community with a shared future for human beings, to protect human rights, the humanitarian spirit, the principle of equality and the idea of justice by playing the role of the state will become a new normal in safeguarding the right to life.

Dynamics and diversity of symbiotic bacteria in Apolygus lucorum at different developmental stages

Background Apolygus lucorum is a worldwide omnivorous pest damaging a range of crops and causing great economic losses.Symbiotic bacteria living in insects play a key role in the nutrition,physiology,and behavior of hosts.Here,we present an experiment using Illumina HiSeq sequencing targeting the V3–V4 regions of bacteria’s 16S rRNA throughout the entire life cycle of A.lucorum.Results The first and second instar nymphs have the largest alpha diversity compared with other life stages of the insect.Bacterial phyla Proteobacteria(72.29%),Firmicutes(15.24%),Actinobacteria(7.76%)exhibit the largest relative abundance in all developmental stages.Erwinia(23.97%)and Lactococcus(10.62%)are the two genera with the high-est relative abundance.The relative abundance of Erwinia in the nymph stage is significantly greater than the adult stage,and the relative abundance of Lactococcus in 6-day-old and 9-day-old adult females is higher compared with adult males.Conclusions These results reveal that microbial community composition and relative abundance shift dynamically at different life stages,implying that different bacterial phyla and genera may have specific roles in specific life stages such as metabolism,nutrition absorption,detoxification,and reproduction.This study reveals for the first time the community composition and ecological dynamics of symbiotic bacteria throughout the life stages of A.lucorum,and thus may provide insight to new strategies for pest control.

Understanding the Unique Characteristics of Suicide in China: National Psychological Autopsy Study

Objective To compare the characteristics of suicides in the four main demographic groups： urban males, urban females, rural males and rural females in order to help clarify the demographic pattern of suicides in China. Methods A detailed psychological autopsy survey instrument was independently administered to 895 suicide victims in family members and close associates from 23 geographically representative locations from around the country. Results Pesticide ingestion accounted for 58% （519） of all suicides and 61% （3181519） of deaths were due to unsuccessful medical resuscitation. A substantial proportion （37%） of suicide victims did not have a mental illness. Among the 563 victims with mental illness, only 13% （76/563） received psychiatric treatment. Compared to other demographic groups, young rural females who died from suicide had the highest rate of pesticide ingestion （79%）, the lowest prevalence of mental illness （39%）, and the highest acute stress from precipitating life events just prior to the suicide. Contusion Many suicides in China are impulsive acts of deliberate self-harm following acute interpersonal crises. Prevention of suicides in China must focus on improving awareness of psychological problems, improving mental health services, providing alternative social support networks for managing acute interpersonal conflicts, limiting access to pesticides, and improving the resuscitation skills of primary care providers.

Self-assessed health and its aspects in the case of Mongolia

Self health assessment is a simple indicator that is widely used for measuring an individual’s perception of his or her overall health. Many studies have been conducted by way of showing which particular aspects should be included in health self assessment, especially in developed world. In the developing world, however, very few studies have examined self health assessment. The aim of this study was to identify particular aspects and associations in self health assessment and differences between subgroups in Ulaanbaatar, Mongolia. The area sampling approach and Kish tables were used for selecting respondents. Total 500 respondents were surveyed by paper-based questionnaires. Spearman’s analysis and multiple logistic regression analysis were used to show relations between variables. Sociodemographic status, such as age and gender, proved to be important in self health assessment. Other factors affecting self health assessment included the number of family members, daily life and lifestyles, social environment, community motivation, and utilization of health services. Women, the elderly, or people with less-than- normal access to information suffer from poor self-assessed health. People who are socially inactive and who have poor living conditions are less likely to use health care services and are likely to assess their health as “poor.” In order to reduce the poor self-assessed health status it is important to address disparities in socioeconomic factors, such as age, gender, employment, and residential area. In addition, more attention should be paid to community and health services, as well as to health promotion and empowerment activities, including income-generation activities. Further research is also needed, however, for better understanding of about the local people and their health-related issues.

Preliminary Explanation on "Natural Activation Theory" Based on "Fenlong"

Based on action mechanism of "Fenlong technology" with the maximum activation potential of global natural resources,"natural resources activation theory"("activation theory") is proposed firstly.Its connotation contains two parts.One is directly activating some natural resources in land,such as unutilized plough bottom of existing cultivated land and soil resources below it,saline-alkali land,degraded grassland,ecological reconstruction of desertification land,inter-row of fruit trees,lawn of sponge city,etc.The other is indirectly activating some natural resources in ground space,such as natural precipitation,solar energy,oxygen,terrestrial eco-environment,soil resources,river waters and even climate change factors.It could release and generate huge physical endogenous force and cyclic force,and increase food source and available water resources,which is favorable for human survival,nature's own ecological balance,harmonious coexistence and balance between man and nature,without harming nature itself.Moreover,its supporting theoretical system is explained from five aspects.It is pointed that the "activation theory" is deep derivation of "Fenlong technology" and "Fenlong science".By sufficiently playing the potential of natural resources,it could reach human-dominated comprehensive balance and coordinated development of air,sunshine,water,soil,nutrient,microorganism,plant,livestock and poultry,marine organism in the nature.The "activation theory" is concrete embodiment of respecting,changing and using the nature,and new channel of realizing sublimation of "life community of human and nature" and benefiting mankind.