Advances in wearable and implantable bioelectronics for precision medicine

The continuous pursuit for a better quality of life promotes continuous advancements in intelligent technology.Flexible wearable and implantable bioelectronics have emerged as an innovative complement to rigid material-based electronic devices[1-3].Due to their distinct advantages in terms of ductile,ultrathin,and biocompatible features,these elastic and soft bioelectronic devices can be seamlessly mounted onto various real or artificial tissues and organs.

Elevational patterns of warming effects on plant community and topsoil properties: focus on subalpine meadows ecosystem

Climate warming profoundly affects plant biodiversity, community productivity, and soil properties in alpine and subalpine grassland ecosystems. However, these effects are poorly understood across elevational gradients in subalpine meadow ecosystems. To reveal the elevational patterns of warming effects on plant biodiversity, community structure, productivity, and soil properties, we conducted a warming experiment using open-top chambers from August 2019 to August 2022 at high(2764 m a. s. l.), medium(2631 m a. s. l.), and low(2544 m a. s. l.) elevational gradients on a subalpine meadow slope of Mount Wutai, Northern China. Our results showed that three years of warming significantly increased topsoil temperature but significantly decreased topsoil moisture at all elevations(P<0.05), and the percentage of increasing temperature and decreasing moisture both gradually raised with elevation lifting. Warming-induced decreasing proportions of soil organic carbon(SOC, by 19.24%), and total nitrogen(TN, by 24.56%) were the greatest at high elevational gradients. Experimental warming did not affect topsoil C: N, p H, NO_(3)^(-)-N, or NH_(4)^(+)-N at the three elevational gradients. Warming significantly increased species richness(P<0.01) and Shannon-Weiner index(P<0.05) at low elevational gradients but significantly decreased belowground biomass(P<0.05) at a depth of 0–10 cm at three elevational gradients. Warming caused significant increases in the aboveground biomass in the three elevational plots. Warming significantly increased the aboveground biomass of graminoids in medium(by 92.47%) and low(by 98.25%) elevational gradients, that of sedges in high(by 72.44%) and medium(by 57.16%) elevational plots, and that of forbs in high(by 75.88%), medium(by 34.38%), and low(by 74.95%) elevational plots. Species richness had significant linear correlations with SOC, TN, and C: N(P<0.05), but significant nonlinear responses to soil temperature and soil moisture in the warmed treatment(P<0.05). The warmed aboveground biomass had a significant nonlinear response to soil temperature and significant linear responses to soil moisture(P<0.05). This study provided evidence that altitude is a factor in sensitivity to climate warming, and these different parameters(e.g., plant species richness, Shannon-Weiner index, soil temperature, soil moisture, SOC, and TN) can be used to measure this sensitivity.

Analysis of optical axis deviation caused by structural stiffness in equatorial telescopes

The impact of structural stiffness on optical axis deviation poses a significant challenge in the design of equatorial telescope structures.A comprehensive analysis during the design process can reduce the reliance of a telescope on advanced control technologies,thereby improving its economic feasibility.Although full-system finite element analyses are reliable,they are encumbered by significant time requirements and limitations in covering all possible telescope orientations.Therefore,we propose an efficient and comprehensive analytical method to evaluate the optical axis deviation of equatorial telescopes across a full range of angles.To address the challenge of ensuring that the analysis covers all possible positions of an equatorial telescope,based on a model from SiTian project,we analyze the optical axis deviations caused by the fork arm at 25 different angles and then use fitting methods to obtain results for all angles.Based on the analysis results of the optical axis deviation caused by the stiffness of the optical tube in the horizontal position,we derive the results for the tube at any position using geometric relationships.Finally,we calculate the coupling factors and combine these impacts.Furthermore,we identify six discrete feature points to reflect possible telescope orientations and conduct comprehensive finite element analyses.The results are in alignment with those acquired through a comprehensive computational approach.

Debris Fan Produced by Failure of Canyon-Blocking Pyroclastic Flows

Ash-rich pyroclastic flows from the cataclysmic eruption of Mount Mazama (~7700 yr. B. P.), Cascade volcanic arc, Oregon, entered and blocked the narrow, bedrock-lined canyon of the Williamson River approximately 35 to 44 km from the source volcano. The blockage impounded a body of water which then released producing four stratigraphic units in the downstream debris fan. The four stratigraphic units are a boulder core comprised of locally sourced bedrock boulders and three sand-rich units including a fine-grained sand unit, a sandy pumice gravel (±basalt/hydrovolcanic tuff) unit, and a pumice pebble-bearing, crystal-rich sand unit. Hand-drilled auger holes up to ~1.6 m deep were used to obtain samples of the sand-rich units. Units were delimited using surface and down-hole observations, composition and texture, estimated density, statistical parameters of grain size, and vertical and lateral distribution of properties. Overtopping followed by rapid incision into the ash-rich pyroclastic flows progressively cleared the canyon, but a bedrock knickpoint near the head of the canyon limited the volume of debris available for transport to about 0.04 km3 to 0.08 km3. Co-deposition of bedrock boulders and lithic-rich sand was followed by rapid deposition with minimal reworking of remobilized pyroclastics. Continued draining of the impounded lake sent hyperconcentrated flows onto the debris fan depositing pumice-rich gravels that graded upward to crystal-rich sands.

Rebuild Trust to Promote Global Recovery

Amid gloomy forecasts for the global economy in 2024,news of China’s 5.2 percent GDP growth in 2023 was a shot in the arm for a world still beset with regional conflicts,lackluster economic recovery,and mounting geopolitical tension.But despite this outstanding economic performance,dire predictions,and assumptions that China’s economy is on the verge of collapse continued to dominate some Western media portals.Certain Western media obstinately dwell on the so-called economic“strains”on China’s economy,despite evidence to the contrary in the National Bureau of Statistics(NBS)of China’s January 17 release of this data.

CHINESE DOCUMENTARIES

Captain Qomolangma Director:Wu Xi Length:One Episode Producer:Mountain Climbing Films,Emei Film Group Broadcasting Platforms:Migu Video,bilibili Sula Wangping was born in a small village at the foot of Mount San’ao in southeastern China’s Sichuan Province.More than 20 years ago,he participated in an expedition to San’ao with China’s national mountaineering team.Being amazed by the grandeur of the snow-capped mountain and obssessed with the exhilaration of climbing,he decided to pursue climbing as a professional career.In June 2019,he led eight amateur mountaineers to the summit of Mount Qomolangma.After overcoming hardships in extreme cold conditions,they became the world’s first team to reach the top of the mountain in 2019.

Volcanic Risk Perception and Coping Strategies from Mounts Cameroon and Nyiragongo Eruptions, Central Africa: A Comparative Analysis

Approximately 2,000,000 people are exposed to volcanic risks in communities situated at the flanks of Mounts Cameroon (MC) and Nyiragongo (MN) volcanoes in Central Africa. This study therefore sought to investigate risk perception from four previous eruptions of MC, namely the 1959, 1982, 1999, and 2000 eruptions;and two previous eruptions of MN: 1977 and 2002. The study was initiated with co-design workshops held with major stakeholders in the cities of Buea and Goma at the flanks of MC and MN, respectively, in 2017, to develop the research objectives for the study. A non-random questionnaire survey was later conducted within 14 and 15 communities in Buea and Goma respectively, on the effects, perceived risks, and coping strategies for the chosen eruptions. Three age groups (18 - 30, 31 - 45 and >45 years) and gender (male and female) were considered. The population at the flanks of both volcanoes cited scientific and indigenous factors to be responsible for eruptions from these volcanoes. At MC and MN, ≥45% of the sampled participants (with a higher female population) perceived that the sampled eruptions posed a very high risk to the population. In terms of the effects, the age group of 18 - 30 was the least knowledgeable. In terms of direct effect on persons, over 90% of participants at MC and MN attested that they were overcome by fear/panic. On measures to cope with any likely eruption, the following order was established at the flanks of both volcanoes: sensitization of population, use of religious (prayers) and of traditional/indigenous strategies. In terms of future coping strategies, while the males at MC maintained sensitization as the favourite option, 62% of the males at MN opted for traditional/indigenous strategies. The female population at both MC and MN showed a higher preference for religious strategies like prayers.

Nature’s Gift

Mount Fanjing Mount Fanjing,located in the eastern Guizhou Province of China,is the highest peak of the Wuling Mountains.Spanning altitude between 500 metres to 2,570 metres above sea level and covering an area of over 775 square km,it emerges as an island of metamorphic rock amid a sea of karst.Established as a nature reserve in 1978 and later designated as a UNESCO Biosphere Reserve in 1986,Mount Fanjing earned further recognition as a UNESCO World Heritage Site in 2018.Mount Fanjing is much taller than it is wide,a vertical pinnacle that resembles a pencil standing on a desk.To reach the top,visitors have to ascend more than 8,000 steps or take a cable car ride up from the road below.

Variations of extreme temperature in the Mount Qomolangma region in China during 1971-2020

According to observational daily temperature data from the meteorological stations during 1971-2020,the variations of the extreme temperature event in the Mount Qomolangma(also known as Mount Everest) region in China have been analyzed using statistical methods.The extreme temperature indices recommended by the World Meteorological Organization are selected to describe the extreme temperature event.The RClimDEX 1.0 software is used to calculate the extreme temperature indices.There are no tropical nights,and just three summer days at the last 50 years.The frost days are the main extreme temperature events all year round.The temperature in the north slope is more extreme than that in the south slope of the Mount Qomolangma.There is remarkable decadal variation for the extreme temperature indices except diurnal temperature range.There are the warm extremes increasing,however,the cold extremes decreasing with the decadal lapse,which is more remarkable into the 21^(th) century.The tendencies for the extreme temperature indices in the north slope are consistent with those in the south slope.There are statistically significant trends for most extreme temperature indices during the study period.It shows that the warm extremes would be more prominent in the future with the global continued warming.The abrupt changes of the extreme temperature index have occurred mainly in the 20^(th) century especially from the mid to late 1980s and 1990s.The periodic changes in the south slope do not synchronize those in the north slope for the most extreme temperature indices.It is different for most extreme temperature indices between the south and north slope,which has demonstrated that the regional or local changes are not neglectable for extreme temperature research.The results of this study are also the consistent response of extreme temperature event to the global warming.

Are the altitudinal patterns of plant diversity derived from field surveys consistent with those from empirical integrated methods?

Field surveys and empirical integrated methods are commonly used in the ecological research to understand the altitudinal pattern of plant diversity of mountains.However,few studies have compared the differences between the two methods on the same scale.Here,we addressed and compared the altitudinal patterns of species richness(SR),phylogenetic diversity(PD),the standardized effect size of phylogenetic diversity(PDses)and mean phylogenetic distance(MPDses)of about 580 angiosperms growing on Mount Kenya from two independent datasets:one is based on our several times field surveys in this mountain and another one is based on empirical data integrated from literatures.We found that the altitudinal diversity patterns of field surveys dataset were consistent with the empirical integrated dataset.Both SR and PD showed hump-shaped patterns along the altitude,and both PDses and MPDses showed monotonically decreasing patterns along the altitude.The ratio of diversity between field surveys dataset and empirical integrated dataset were gradually increase along the altitude.Our research provides new insight for understanding the altitudinal diversity patterns of plants of a tropical mountain.

Cavefish mount a rapid and sustained regenerative response following skeletal muscle injury

Dear Editor,Physical injury and tissue damage are prevalent throughout the animal kingdom,with the ability to regenerate quickly and efficiently providing a selective advantage.In most vertebrates,skeletal muscle possesses a remarkable ability to regenerate,making it a valuable model for investigating the cellular processes underpinning tissue regeneration.Following damage,skeletal muscle mounts a complex regenerative cascade centered around dedicated muscle stem cells,i.e.,satellite cells.These satellite cells are,in turn,regulated by both resident and infiltrating innate immune cells of myeloid lineage,which play a crucial role in activating and guiding the transition of satellite cells towards maturation(Chen et al.,2020;Tidball,2017;Tidball&Villalta,2010).While critical for muscle regeneration,the innate immune system is energetically costly,resulting in many species decreasing immune investment under nutrient-limited environments.Whether this reduced investment results in a decreased capacity to mount a regenerative response following tissue damage remains unclear.Here,we utilized an emerging evolutionary model,the Mexican tetra(Astyanax mexicanus),to investigate the consequences of shifts in immune system investment on skeletal muscle regeneration.

A Comparison Study of Synkinematic Illite Isolation,Quantitative X-ray Powder Diffraction,and K-Ar Dating for Direct Fault Gouge Analyses

K-Ar dating of synkinematic illite is increasingly recognized as a central method to constrain the timing of shallow crustal faulting.Methods of efficient sample preparation and quantitative identification of illite polytypes are critical to acquiring K-Ar isotope data for authigenic clays.In this respect,we compared the commonly used clay size separation method through centrifugation with vacuum filtration technology,showing that the former is prone to extract fractions with finer particle sizes under similar conditions,thus improving the error in the authigenic end-member age.Additionally,we demonstrated that the side-packed mounting method for X-ray diffraction analysis can significantly enhance the randomness in powder samples,thus improving the quantification accuracy compared with the front-packed and back-packed methods.The validity of our quantification method was confirmed by comparing Profex■modeling patterns with a suite of synthetic mixtures of known compositions,yielding an average analytical error of 3%.Dating results of these artificial mixtures and the reference materials indicated that a large range in percentages of detrital illite and a sufficient amount of age data will produce reliable results for ages of both extrapolated end-members.However,if the range is limited,the extrapolated age close to those of datasets is still reliable.

Identification of major sources controlling groundwater geochemistry in Mount Makabaï in the Far-North of Cameroon(the northernmost part of the Pan-African Belt)

The present work focuses on the volcanic basement rock geochemistry of Mount Makabaï(MarouaCameroon city)in relation to groundwater geochemistry.Investigations were centered on an approach involving an association of several methods such as geological cartography,hydrogeology,and geochemistry.Three rock samples,four disturbed soil samples,three undisturbed soil samples,and 20 samples of groundwater in 10 wells were collected during fieldwork and prepared for laboratory analyses.Bedrocks exhibit porphyritic,aphyric,and subaphiric textures.The phenocryst phases are mainly olivine,clinopyroxene,and plagioclase.Based on whole rock major element chemical compositions,the Makabaï samples,plotted on Na_(2)O+K_(2)O versus SiO_(2)diagram,are mugearite,hawaiite,and basalt.The ratio of(MgO+CaO)/(Na_(2)O+K_(2)O)exceeds unity and shows dominance of alkaline Earth metals(MgO:2.99-4.48%;CaO:6.19-9.80%)relatively to alkali metals(Na_(2)O:2.27-4.46%;K_(2)O:2.09-2.51%).Exchangeable base contents are high,mostly represented by Ca and Mg,whose contents vary from 14.6 to 35.28 cmol(+)kg^(-1)and from 3.28 to9.48 cmol(+)kg^(-1)respectively.The CECclayis likewise high,fluctuating between 116.80 and181.38 cmol(+)kg^(-1),values in line with the presence of 2:1 clay minerals represented in the study area by montmorillonite.In the water samples,the Ca2+and Na+contents are generally higher than K^(+)and Mg^(2+),reflecting the relative abundance of Na_(2)O and CaO oxides to K_(2)O and MgO oxides in rocks where different waters were sampled.The waters of Makabaï are acidic to neutral(6.3≤pH≤7.4)and weakly to highly mineralized(110.0≤EC≤1190.0μS/cm).Hydro-geochemical classification by using the Piper diagram revealed two water types:(1)CaMg-HCO_(3)(40%)and(2)CaMg-Cl or CaMg-SO4(60%).The average content of ions in all the analyzed samples was HCO_(3)^(-)>>NO_(3)^(-)>SO_(4)^(2-)>Cl-for anions and Ca^(2+)>>Mg^(2+)>Na^(+)>K^(+)for cations.Major mechanisms governing ionic constituents of groundwater in the study area are water-rock interactions,silicate weathering,and ion exchange.

澳大利亚Bigrlyi铀矿床成矿特征与控矿因素研究

Bigrlyi铀矿床位于澳大利亚北领地Ngalia盆地北缘,主要由A2/A3矿体、A4矿体、A7矿体、A15矿体等四个矿体组成,是一个典型的砂岩型铀矿床。Ngalia盆地为一个北陡南缓的不对称型山间残留盆地,盆地盖层主要由上元古界(~850 Ma)和古生界陆相沉积物组成,受晚奥陶世~晚石炭世Alice Springs造山运动(ASO)的影响,盆地内泥盆~石炭系Mount Eclipse组砂岩与下伏所有地层均呈不整合接触,是盆地内砂岩型铀成矿的主要含矿层位。Mount Eclipse组砂岩沉积于前陆盆地环境,发育河流、(扇)三角洲和湖泊沉积体系,含矿岩石主要为位于C单元的灰色长石砂岩及杂砂岩,铀矿物主要为沥青铀矿和铀石,脉石矿物为石英、钾长石及少量的黏土矿物。盆地砂岩型铀成矿作用主要受铀源、沉积、构造等因素的控制,其中在沉积成岩期的构造挤压与基底抬升不仅沉积了一套有利的含矿岩系,而且在该岩层内形成了铀的初始预富集及局部铀矿化,在沉积期后的持续挤压作用与逆冲推覆作用下,使得含矿岩系抬升并出露地表,接受来自蚀源区含铀含氧水的渗入,并在氧化还原过渡带内形成似卷状或“板状”富铀矿体。

Exploration of the Construction of the National Scenic Byway around Mount Tai

On the basis of traffic,scenic byways can meet tourists’tourism and leisure,catering,accommodation,social,activities,resource protection and so on.In this paper,the concept,functions,characteristics and domestic and foreign research situation of scenic byways were summarized,and the necessity and feasibility of the construction of the national scenic byway around Mount Tai were analyzed.Besides,the route selection,function orientation,construction of supporting facilities,marketing management and construction projects were discussed.Finally,it is pointed out that the construction experience of the national scenic byway around Mount Tai will be used for the construction of national scenic byways in other provinces and autonomous regions,and the national scenic byway around Mount Tai and other national scenic byways will be connected to form the national scenic byway network.It is proposed that relevant departments of the state should formulate national standards,laws and regulations for scenic byways to regulate the construction and development of scenic byways.

Petrochemical Studies of Fouimba and Goma Mounts, Central-West of Cote d’Ivoire: Implication on Petrogenesis Tectonic Setting

Petrogeochemical analysis of mafic rocks of Fouimba and Goma Mount in the Séguéla region (central-western Côte d’Ivoire) is the subject of this study. This analysis combines remote sensing, geophysics, petrography and geochemistry, in order to determine the major characteristics of the mafic formations in the said area, and above all to participate in the detailed mapping of all the Ivorian terrains. The mafic formations encountered in this region are essentially metatonalites to metadiorites, amphibolites, amphibole bearing pyroxenites and porphyry basalts. Chemical analysis indicates that these mafic formations are tonalitic to monzonitic. They are thought to have derived from mantle depleted magmas.

Research on the Exploitation of Study Tour Resources in Mount Taishan

Mount Taishan in Taian Prefecture of Shandong Province has rich study tour resources,but its development efforts are extremely disproportionate to its status as one of the five unique mountains.Through analyzing study tour in the context of its development and study tour resources in Mount Taishan,and based on the in-depth analysis of the existing problems,the proposals for the development of resources were put forward:highlight the main line and enrich the study activities to create study bases around Mount Taishan;improve the study services through the research and development of special products;expand the publicity to promote the educational products and research products.

Championing Global Cooperation to Crack Global Challenges

Agronomist Thomas A.Lumpkin,one of the first American exchange students in the People’s Republic of China since the two countries established diplomatic ties in 1979,and also a recipient of the Chinese government’s Friendship Award,calls for greater cooperation to cope with mounting global challenges.

Championing Global Cooperation to Crack Global Challenges

Agronomist Thomas A.Lumpkin,one of the first American exchange students in the People’s Republic of China since the two countries established diplomatic ties in 1979,and also a recipient of the Chinese Government’s Friendship Award,calls for greater cooperation to cope with mounting global challenges.

Mount Taishan:The Supreme of the Five Sacred Mountains

MOUNT Taishan is one of the spiritual symbols of Chinese civilization,and an imperial,ritual place where emperors once paid homage to heaven and earth.Located in the central part of east China’s Shandong Province,Mount Taishan stretches more than 200 kilometers from east to west and 50 kilometers from north to south,with a total area of about 426 square kilometers and a maximum altitude of 1,545 meters.In ancient times.