Alzheimer’s disease（AD）,the main cause of dementia,is defined by the combined presence of amyloid-b（Ab）deposition and abnormal tau aggregation[1].Experimental models are critical to obtain a better understanding ...Alzheimer’s disease（AD）,the main cause of dementia,is defined by the combined presence of amyloid-b（Ab）deposition and abnormal tau aggregation[1].Experimental models are critical to obtain a better understanding of AD pathogenesis,and to evaluate the potential of novel therapeutic approaches.The most commonly used AD展开更多
基金partly supported by grants from the National Key Research and Development Program of China(2016YFA0100900)the International S&T Cooperation Program of China(2015DFG32740)the National Natural Science Foundation of China(81571711 and 81425015)
文摘Alzheimer’s disease（AD）,the main cause of dementia,is defined by the combined presence of amyloid-b（Ab）deposition and abnormal tau aggregation[1].Experimental models are critical to obtain a better understanding of AD pathogenesis,and to evaluate the potential of novel therapeutic approaches.The most commonly used AD
