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Linguistic landscape and its impacts on place-making in mountain destination:A case of Mogan Mountain Town of Huzhou City,China
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作者 LI Chenyan LU Song +1 位作者 LONG Cheng ZHU Jiaheng 《Journal of Mountain Science》 SCIE CSCD 2024年第5期1613-1629,共17页
The place and placeness are believed to be a crucial perspective for comprehending the transformative dynamics of tourist destinations in the context of globalization and the rapid development of the tourism industry.... The place and placeness are believed to be a crucial perspective for comprehending the transformative dynamics of tourist destinations in the context of globalization and the rapid development of the tourism industry.As the material carrier of language,linguistic landscape is an intermediary for people to endow emotions and personalities into the place,becoming an effective path for exploring the place-making in a certain area.Mogan Mountain is a famous national tourist resort,which is located in Mogan Mountain Town,Deqing County,Huzhou City,China.This is a good case area for studying the relationship between linguistic landscape and placemaking in tourist destinations.There are two theories that form the theoretical foundation of the study,namely the place and the geosemiotics.Firstly,the results showed the overall style of the linguistic landscape.Multilingual labelling(52.7%),official signs(55.3%),and standardized Chinese characters predominantly shaped the linguistic landscape,with English and other languages being complementary.Secondly,from the perspective of three dimensions of the geosemiotics framework,such as inscription,language preference,and placement position,we conduct a comprehensive semiotic analysis of the linguistic landscape,which encompasses diverse facets such as fonts,materials,shifts in state,text vectors,and symmetrical arrangements.Finally,we explore the influence of linguistic landscapes on the place-making of Mogan Mountain through the dimensions of location,locale,and sense of place.The information on linguistic landscapes indicates the geographical location.These linguistic landscapes play an important role in constructing the language order,nostalgic atmosphere,exotic atmosphere,and elegant and tasteful lifestyle of the public space in Mogan Mountain.Readers of linguistic landscapes,including tourists and residents,generate and identify with the unique sense of place in Mogan Mountain.These linguistic landscapes construct the destination placeness of Mogan Mountain that combines both foreign and nostalgic styles,and the integration of Chinese and Western cultures.It will help promote the image positioning of tourism destinations and have practical guiding significance for the tourism planning,landscape-making,language management,and other aspects of tourism destinations. 展开更多
关键词 Linguistic landscape place-MAKING tourist destination Geosemiotics place theory place branding Mogan Mountain town China
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Diverse foraging strategies of breeding Swinhoe's Storm-petrel in the productive marginal sea of the Northwest Pacific
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作者 Yachang Cheng Lei Zhu +6 位作者 Lin Xue Shisheng Ma Nan Jia Shaoping Zang Zhihai Cao Jing Yuan Yang Liu 《Avian Research》 SCIE CSCD 2024年第1期27-34,共8页
Understanding the foraging behavior is essential for investigating seabird ecology and conservation,as well as monitoring the well-being of the marine environment.Breeding seabirds adopt diverse foraging strategies to... Understanding the foraging behavior is essential for investigating seabird ecology and conservation,as well as monitoring the well-being of the marine environment.Breeding seabirds adopt diverse foraging strategies to maximize energy gains and cope with the intensified challenges of parenting and self-maintenance.Such tradeoff may stem from the heterogeneity of food resources and the constraints of central place foraging.Nevertheless,abundant marine productivity could alleviate the energy limitation for seabirds,resulting in a consistent foraging approach.Here,we investigated the foraging strategy during the breeding season of a cryptic small-sized seabird,Swinhoe’s Storm-petrel(Hydrobates monorhis),in the Yellow Sea,a productive marginal sea of the Northwest Pacific.Using GPS tracking,we evaluated habitat preference,quantified the foraging strategy,and tested if environmental conditions and individual traits influence foraging trips.We found that Swinhoe’s Storm-petrels preferred nearshore areas with shallow water and engaged in primarily short foraging trips.Distinctive southeastward and southwestward strategies emerged when combining trip metrics,including foraging direction,duration,and maximum distance.The bathymetry,proximity to the coastline,and sea surface temperature differed in two foraging strategies.Foraging strategies exhibited flexibility between individuals,potentially explained by wing morphology,in which longer-winged birds are more likely to embark on longer-distance foraging trips.These findings highlight the impact of environmental factors and individual traits on seabirds’foraging decisions in productive marginal sea ecosystems.Our study also provides valuable insights into the foraging ecology of this Asian endemic storm-petrel. 展开更多
关键词 Behavioral strategy BIOLOGGING Central place foraging Marine primary productivity Seabird Sea surface temperature
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Mindfulness training in medical education as a means to improve resilience,empathy,and mental health in the medical profession
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作者 Edison Iglesias de Oliveira Vidal Luiz Fernando Alvarenga Ribeiro +1 位作者 Marco Antonio de Carvalho-Filho Fernanda Bono Fukushima 《World Journal of Psychiatry》 SCIE 2024年第4期489-493,共5页
The high rates of depression,burnout,and increased risk of suicide among medical students,residents,and physicians in comparison with other careers signal a mental health crisis within our profession.We contend that t... The high rates of depression,burnout,and increased risk of suicide among medical students,residents,and physicians in comparison with other careers signal a mental health crisis within our profession.We contend that this crisis coupled with the inadequate acquisition of interpersonal skills during medical education results from the interaction between a challenging environment and the mental capital of individuals.Additionally,we posit that mindfulness-based practices are instrumental for the development of major components of mental capital,such as resilience,flexibility of mind,and learning skills,while also serving as a pathway to enhance empathy,compassion,self-awareness,conflict resolution,and relational abilities.Importantly,the evidence base supporting the effectiveness of mindfulness-based interventions has been increasing over the years,and a growing number of medical schools have already integrated mindfulness into their curricula.While we acknowledge that mindfulness is not a panacea for all educational and mental health problems in this field,we argue that there is currently an unprecedented opportunity to gather momentum,spread and study mindfulness-based programs in medical schools around the world as a way to address some longstanding shortcomings of the medical profession and the health and educational systems upon which it is rooted. 展开更多
关键词 MINDFULNESS Medical education Mental capital Mental health Medical students RESILIENCE
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Making the World a Better Place for All
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作者 ZHANG HUI 《China Today》 2024年第2期16-20,共5页
In bidding farewell to 2023,Chinese President Xi Jinping’s New Year message,with its commitment to advance Chinese modernization,deliver a better life for the people,and build a community with a shared future for man... In bidding farewell to 2023,Chinese President Xi Jinping’s New Year message,with its commitment to advance Chinese modernization,deliver a better life for the people,and build a community with a shared future for mankind,effectively ushered in a new year brimming with hope. 展开更多
关键词 COMMITMENT place World
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Impact of web-based positive psychological intervention on emotions,psychological capital,and quality of life in gastric cancer patients on chemotherapy
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作者 Yu-Yu Xin Dan Zhao 《World Journal of Clinical Cases》 SCIE 2024年第26期5877-5884,共8页
BACKGROUND Gastric cancer is a malignant digestive tract tumor that originates from the epithelium of the gastric mucosa and occurs in the gastric antrum,particularly in the lower curvature of the stomach.AIM To evalu... BACKGROUND Gastric cancer is a malignant digestive tract tumor that originates from the epithelium of the gastric mucosa and occurs in the gastric antrum,particularly in the lower curvature of the stomach.AIM To evaluate the impact of a positive web-based psychological intervention on emotions,psychological capital,and quality of survival in gastric cancer patients on chemotherapy.METHODS From January 2020 to October 2023,121 cases of gastric cancer patients on chemotherapy admitted to our hospital were collected and divided into a control group(n=60)and an observation group(n=61)according to the admission order.They were given either conventional nursing care alone and conventional nursing care combined with web-based positive psychological interventions,respectively.The two groups were compared in terms of negative emotions,psychological capital,degree of cancer-caused fatigue,and quality of survival.RESULTS After intervention,the number of patients in the observation group who had negative feelings toward chemotherapy treatment was significantly lower than that of the control group(P<0.05);the Positive Psychological Capital Questionnaire score was considerably higher than that of the control group(P<0.05);the degree of cancer-caused fatigue was significantly lower than that of the control group(P<0.05);and the Quality of Life Scale for Cancer Patients(QLQ-30)score was significantly higher than that of the control group(P<0.05).CONCLUSION Implementing a web-based positive psychological intervention for gastric cancer chemotherapy patients can effectively improve negative emotions,enhance psychological capital,and improve the quality of survival. 展开更多
关键词 Internet Positive psychology Gastric cancer chemotherapy Negative emotions Psychological capital Quality of survival
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Defining Cities by Water: Addressing Capital Misallocation in a Race to Conserve Resources
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作者 Yao Peng Li Jinze 《China Economist》 2024年第1期86-102,共17页
As part of its efforts to promote a sustainable and high-quality development,China has pledged to reduce water consumption and create a water-efficient society.On the basis of identifying the institutional root causes... As part of its efforts to promote a sustainable and high-quality development,China has pledged to reduce water consumption and create a water-efficient society.On the basis of identifying the institutional root causes of excessive capital allocation and excessive water consumption in China’s water-intensive industrial sectors,this study elaborates how the national water-efficient cities assessment contributes to optimized capital allocation.Our research shows that national water-efficient cities assessment has motivated local governments to compete for water efficiency.To conserve water,local governments regulated the entry and exit of water-intensive enterprises,discouraged excessive investments in water-intensive sectors,and phased out obsolete water-intensive capacities within their jurisdictions.This approach has resulted in mutually beneficial outcomes,including improved allocation of capital,enhanced water efficiency,and reduced emissions.This paper offers policy recommendations for establishing a water-efficient society throughout the 14^(th) Five-Year Plan(2021-2025)period by presenting empirical evidence on the policy effects of resource efficiency evaluation. 展开更多
关键词 Competitive evaluation for resource efficiency national water-efficient cities assessment capital misallocation water efficiency emissions abatement
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Analysis of the Appealing Structure in Hemingway’s“A Clean,Well-lighted Place”
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作者 LI Xing-yue 《Journal of Literature and Art Studies》 2024年第3期201-206,共6页
In the novel“A Clean,Well-lighted Place”,Hemingway tells the story of two waiters in a Spanish caféjust before closing time,talking about an old man who drank heavily in the caféevery night and lived a wea... In the novel“A Clean,Well-lighted Place”,Hemingway tells the story of two waiters in a Spanish caféjust before closing time,talking about an old man who drank heavily in the caféevery night and lived a wealthy life but still wants to commit suicide.Using the iceberg principle,Hemingway purposely omits the plot,characterization of the story,and uses symbolism and repetition to describe people’s different attitudes facing the spiritual emptiness after the war,breaking the readers’expectations,and inspiring them to explore the meaning of individual life.Therefore,based on Wolfgang Iser and Zhu Liyuan’s appealing structure theory,this paper will analyze the appealing structure in“A Clean,Well-lighted Place”at three levels:meaning construction,rhetorical techniques,and thoughts and themes.It is hoped that readers can find a new way to interpret the short story,better understand the author’s creative ideas and dig deeper into the connotation of the work. 展开更多
关键词 Ernest Hemingway “A Clean Well-lighted place appealing structure
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Construction of Regional Ecological Capital Operation Mechanism System from the Perspective of Green Economy Development
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作者 Wanxuan WU Jialin LIU Xieyu XIONG 《Meteorological and Environmental Research》 2024年第4期44-48,共5页
Green development has gradually become the main theme of the current world economic development.Green transformation development and cracking the contradiction between ecology and economy need to build an effective ec... Green development has gradually become the main theme of the current world economic development.Green transformation development and cracking the contradiction between ecology and economy need to build an effective ecological capital operation system and mechanism to support,encourage the effective operation of regional ecological capital,promote the appreciation and preservation of ecological capital,and escort the operation.This paper constructs a four-in-one regional ecological capital operation mechanism system,in which the"accumulation mechanism"is the prerequisite,the"conversion mechanism"is the key link,the"compensation mechanism"is an important supplement,and the"incentive mechanism"is the safeguard measure,which aims to ensure the smooth progress of the construction of beautiful China in the new era and realize the socialist modern power. 展开更多
关键词 Green economy Value realization of ecological products Ecological capital operation
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The Interrelationship between Culture and Capital Structure:Evidence from International Retailers
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作者 Sisi Xu 《Proceedings of Business and Economic Studies》 2024年第2期66-72,共7页
The present study investigates the influence of cultural factors in 2022 on the capital structure of global retailers.There are sixteen retailers from eight countries in the sample.In recent times,numerous academician... The present study investigates the influence of cultural factors in 2022 on the capital structure of global retailers.There are sixteen retailers from eight countries in the sample.In recent times,numerous academicians have taken an interest in examining the capital structure and business model of retailers,owing to their swift and consistent growth.However,the fact that the majority of research originates from the retailers’host country gives rise to debate regarding the applicability of the capital structure of said retailers to countries with distinct cultural environments.Consequently,academics have begun to investigate whether the capital structure of multinational retailers is impacted by the diversity of national cultures. 展开更多
关键词 Cultural factors capital structure Global retailers Business model National cultures
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Venture Capital Syndication under Social Network Theory:Literature Review and Prospect
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作者 Junru Zhao Shasha Yang Zhengbin Wang 《Proceedings of Business and Economic Studies》 2024年第4期10-15,共6页
As an important channel for start-ups to obtain R&D funds and external knowledge and information resources,and as one of the key methods for investment institutions to leverage scale and synergy effects to enhance... As an important channel for start-ups to obtain R&D funds and external knowledge and information resources,and as one of the key methods for investment institutions to leverage scale and synergy effects to enhance investment returns,venture capital syndication holds significant research value in the field of venture capital.This paper reviews the literature,summarizing the motivations behind the formation of joint investment networks,the conceptual characteristics of the three core theories of social network theory,and the empirical research on venture capital syndication within the framework of social network theory.It also highlights the existing research results,identifies gaps,and anticipates future research directions. 展开更多
关键词 Social network theory Venture capital syndication investment
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An Extended Fuzzy-DEMATEL System for Factor Analyses on Social Capital Selection in the Renovation of Old Residential Communities
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作者 Guoshuai Sun Xiuru Tang +1 位作者 Shuping Wan Jiao Feng 《Computer Modeling in Engineering & Sciences》 SCIE EI 2023年第2期1041-1067,共27页
China has been promoting the renovation of old residential communities vigorously.Due to the financial pressure of the government and the sustainability of the renovation of old residential communities,public-private ... China has been promoting the renovation of old residential communities vigorously.Due to the financial pressure of the government and the sustainability of the renovation of old residential communities,public-private partnerships(PPP)have already gained attention.The selection of social capital is key to improving the efficiency of the PPP model in renovating old residential communities.In order to determine the influencing factors of social capital selection in the renovation of old residential communities,this paper aims to find an effective approach and analyze these factors.In this paper,a fuzzy decision-making and trial evaluation laboratory(fuzzy-DEMATEL)technique is extended and amore suitable systemis developed for the selection of social capital using the existing group decisionmaking theory.In the first stage,grounded theory is used to extract the unabridged key influencing factors for social capital selection in the renovation of old residential communities.Secondly,by considering the impact of expert weights,the key influencing factors are identified.The interactions within these influencing factors are discussed and the credibility of the results is verified by sensitivity analysis.Finally,these key influencing factors are sorted by importance.Based on the results,the government should focus on a technical level,organizationalmanagement abilities,corporate reputation,credit status,etc.This study provides the government with a theoretical basis and a methodology for evaluating social capital selection. 展开更多
关键词 Social capital selection fuzzy-DEMATEL influencing factors renovation of old residential communities grounded theory
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Female directors in the boardroom and intellectual capital performance:Does the“critical mass”matter?
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作者 Hafiz Mustansar Javaid Qurat Ul Ain Rita D’Ecclesia 《Financial Innovation》 2023年第1期1995-2018,共24页
This research aims to investigate the influence of female directors on Intellectual Capital Performance(ICP)using a sample of manufacturing-listed companies in China.Our study investigates the link between having two ... This research aims to investigate the influence of female directors on Intellectual Capital Performance(ICP)using a sample of manufacturing-listed companies in China.Our study investigates the link between having two or more female directors and the Modified Value-Added Intellectual Coefficient(MVAIC)methodology,employing the critical mass theory from 2004–2017.We find that having a critical mass of female directors(three or more)shows a significant positive impact on MVAIC and its components,including human capital efficiency,structural capital efficiency,relational capital efficiency,and physical capital efficiency,with physical capital being the critical driver.Our study reveals that the critical mass participation of female directors substantially influences the IC efficiency of privately owned companies compared to state-owned companies.Moreover,the number of female directors also affects the IC performance of manufacturing companies in multiple regions.Our findings support the validity of group classification identified by Kanter and Critical Mass Theory.To the best of our knowledge,this is one of the few pieces of research that studies the role of female board directors in IC performance and Chinese manufacturing firms using MVAIC as an IC measure. 展开更多
关键词 Corporate governance Female directors Critical mass Intellectual capital State-owned enterprises(SOEs) China
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A Critical Review of the Effects of Stock Returns and Market Timing on Capital Structure
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作者 YE Hongru JI Jie ZOU Yuanyuan 《Management Studies》 2023年第6期312-321,共10页
Capital structure is regarded as the combination of debt and equity firms used to finance operations and investments.The choice of capital structure significantly impacts a company’s cost of capital,profitability,and... Capital structure is regarded as the combination of debt and equity firms used to finance operations and investments.The choice of capital structure significantly impacts a company’s cost of capital,profitability,and risk profile.Among a series of factors that affect capital structure,this paper focuses on stock returns and market timing.In this review,an array of papers is analyzed to summarize what current research claims regarding the influence of stock returns and market timing on capital structure.This paper centers on the stock return and market timing theories and also discusses other theories like the trade-off theory,the pecking order theory,and the signaling theory. 展开更多
关键词 capital structure stock returns market timing
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A First Tour of Wulong Pool——Nanjing city, the ancient capital of six dynasties, had kept lots of interesting places and historical relics for us to explore.
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作者 Zeng Liping 《China's Foreign Trade》 1994年第11期110-110,共1页
Last October, the Nanjing-based aiwan, Hongkong, Macao and verseas Chinese Literature Society went to Wulong Pool. Zhang Chao, vice-chairman of the society, invited me to go to see the place with him. We went eastward... Last October, the Nanjing-based aiwan, Hongkong, Macao and verseas Chinese Literature Society went to Wulong Pool. Zhang Chao, vice-chairman of the society, invited me to go to see the place with him. We went eastward out of Longpanli along bustling and seething Guangzhou Avenue. by the side of the high Suolong Bridge, we found a garden gate with flower- 展开更多
关键词 A First tour of Wulong Pool Nanjing city had kept lots of interesting places and historical relics for us to explore the ancient capital of six dynasties
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How to Prepare the Accounting Entry on the Basis of Capital Movement
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作者 Jianwen Huang 《Journal of Modern Accounting and Auditing》 2006年第6期16-20,共5页
It is well known that economic transactions must be prepared the accounting entries before they are registered in account books. Therefore, it's the most important procedure in the whole accounting work to prepare th... It is well known that economic transactions must be prepared the accounting entries before they are registered in account books. Therefore, it's the most important procedure in the whole accounting work to prepare the accounting entries correctly. This paper puts forward how to prepare the accounting entry on the basis of capital movement because the traditional method is so complex, abstract and incomprehensible to be mastered by beginners. The research shows that the new method proposed in the paper is very direct, pictorial, and concrete. It is very easy to be mastered by a beginner of accounting. 展开更多
关键词 capital movement accounting entry ACCOUNTS TRANSACTIONS
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Game theory approach to optimal capital cost allocation in pollution control 被引量:8
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作者 Chen Wen ying Institute of Nuclear Energy Technology, Tsinghua University, Beijing 100084,China Hou Dun Urban Water Resources Center, Ministry of Construction, Beijing 100007,China 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 1998年第2期104-110,共7页
This paper tries to integrate game theory, a very useful tool to resolve conflict phenomena, with optimal capital cost allocation issue in total emission control. First the necessity of allocating optimal capital cos... This paper tries to integrate game theory, a very useful tool to resolve conflict phenomena, with optimal capital cost allocation issue in total emission control. First the necessity of allocating optimal capital costs fairly and reasonably among polluters in total emission control was analyzed. Then the possibility of applying game theory to the issue of the optimal capital cost allocation was expounded. Next the cooperative N person game model of the optimal capital cost allocation and its solution ways including method based on Shapley value, least core method, weak least core methods, proportional least core method, CGA method, MCRS method and so on were delineated. Finally through application of these methods it was concluded that to apply game theory in the optimal capital cost allocation issue is helpful to implement the total emission control planning schemes successfully, to control pollution effectively, and to ensure sustainable development. 展开更多
关键词 total emission control optimal capital cost allocation game theory cooperative N person game model.
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Rice Growers' Behavior of Productive Capital Input and the Influencing Factors——A Case Study of the Jiamusi Area in Heilongjiang Province 被引量:2
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作者 GAO Lei 《Asian Agricultural Research》 2012年第6期19-23,共5页
This article conducts empirical analysis of rice growers' behavior of productive capital input and the influencing factors,using the input-output survey data concerning rice growing by 305 peasant households in 20... This article conducts empirical analysis of rice growers' behavior of productive capital input and the influencing factors,using the input-output survey data concerning rice growing by 305 peasant households in 2009 in Huanan County and Huachuan County,Jiamusi City,Heilongjiang Province.I use Logit model to carry out econometric test of factors influencing the possibility of fixed productive investment.The test results show that family size,the proportion of non-agricultural employment,the average educational level of households,farmland area,household farming income,credit level,peasant households' expectation of the minimum purchase price of rice,have significant effect on whether to conduct fixed productive investment,whether there are disasters has no significant effect on the scale of peasant households' productive investment.Then I use Tobit model to carry out econometric test of factors influencing the scale of productive capital input.The results show that family size,the proportion of non-agricultural employment,the average educational level of households,farmland area,household farming income,credit level and family housing value,peasant households' expectation of the minimum purchase price of rice,whether there are disasters,have significant effect on the scale of peasant households' productive investment.On the basis of model test results,in order to promote the rice growers to increase fixed productive input and increase productive capital input,rational recommendations are put forward as follows:raising the minimum purchase price of rice,scaling up rice growing,making every effort to promote the educational level of rice growers,ensuring that the rice growers obtain productive capital input loans timely. 展开更多
关键词 RICE GROWERS Productive capital INPUT Fixed produc
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Microinjection of Ghrelin into the Ventral Tegmental Area Potentiates Cocaine-Induced Conditioned Place Preference 被引量:2
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作者 Lindsey M. Schuette Christopher C. Gray Paul J. Currie 《Journal of Behavioral and Brain Science》 2013年第8期576-580,共5页
Prior work has shown that systemic cocaine pretreatment augments cocaine conditioned place preference (CPP) in rats. In contrast, ghrelin receptor antagonism attenuates cocaine and amphetamine-induced CPP. In order to... Prior work has shown that systemic cocaine pretreatment augments cocaine conditioned place preference (CPP) in rats. In contrast, ghrelin receptor antagonism attenuates cocaine and amphetamine-induced CPP. In order to further investigate ghrelin’s role in dopamine-mediated reward, the present report examined whether pretreament with ghrelin, administered directly into the ventral tegmental area (VTA) of the midbrain, would potentiate the rewarding properties of cocaine as measured by CPP. Adult male Sprague-Dawley rats were given access to either side of the CPP chamber in order to determine initial side preferences. The rats were then restricted to either their non-preferred or preferred side over the course of conditioning which lasted for a total of 16 consecutive days. This was followed by a final test day to then reassess preference. On days where rats were confined to their non-preferred side, ghrelin (30-300 pmol) and cocaine (0.625-10 mg/kg IP) were administered immediately prior to the conditioning trial. On alternate days rats were treated with vehicle and placed into what was initially determined to be their preferred side. CPP was calculated as the difference in percentage of total time spent in the treatment-paired compartment during the post-conditioning session and the pre-conditioning session. Our results indicated that both cocaine and ghrelin elicited CPP and that ghrelin pretreatment potentiated the effect of cocaine on place preference. Overall, these findings provide additional support for the argument that ghrelin signaling within the VTA enhances the rewarding effects of psychostimulant compounds. 展开更多
关键词 COCAINE Conditioned place Preference GHRELIN PSYCHOSTIMULANT MIDBRAIN VENTRAL Tegmental Area
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Effect of glycine site/NMDA receptor antagonist MRZ2/576 on the conditioned place preference and locomotor activity induced by morphine in mice 被引量:4
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作者 ZHU Yong-ping LONG Zai-hao +1 位作者 ZHENG Ming-lan BINSACK Ralf 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2006年第12期998-1005,共8页
Objective: To study the effect of glycine site/NMDA (N-methyl-D-aspartate) receptor antagonist MRZ2/576 on the conditioned place preference (CPP) and locomotor activity induced by morphine in mice. Methods: Different ... Objective: To study the effect of glycine site/NMDA (N-methyl-D-aspartate) receptor antagonist MRZ2/576 on the conditioned place preference (CPP) and locomotor activity induced by morphine in mice. Methods: Different doses (1.25, 2.5 and 5 mg/kg, i.p.) of MRZ2/576 were used to evaluate the effect of MRZ2/576 on the acquisition and expression of CPP induced by morphine (5 mg/kg) in mice. In addition, we examined the locomotor activity of mice in conditioning and testing phase of CPP paradigm. Results: MRZ2/576 alone could not establish place preference, but a 5 mg/kg dose of MRZ2/576 could block both acquisition and expression of morphine-induced CPP. In testing phase of CPP, there was no statistical difference for locomotor activity between the groups; injection of MRZ2/576 showed a dose-dependent decrease of locomotor activity on both control and morphine-treated mice, especially 5 mg/kg of MRZ2/576 significantly suppressed the locomotor activity of mice. Conclusion: Based on the present results, we assume that MRZ2/576 can antagonize the rewarding effect of morphine, suggesting that this glycine site/NMDA receptor antagonist could be used to treat addictions due to its light side effect profile. 展开更多
关键词 MORPHINE MRZ2/576 NMDA receptor Glycine site Conditioned place
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Moment tensor inversion of small to moderate earthquakes in the Capital Region in 2004 被引量:1
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作者 许力生 蒋长胜 +2 位作者 陈运泰 李春来 张天中 《Acta Seismologica Sinica(English Edition)》 CSCD 2007年第3期243-253,共11页
The moment tensor solutions of 51 small to moderate earthquakes occurred in the Capital Region in the year of 2004 are obtained by inverting the broadband waveform data. Accordingly, other source parameters, such as s... The moment tensor solutions of 51 small to moderate earthquakes occurred in the Capital Region in the year of 2004 are obtained by inverting the broadband waveform data. Accordingly, other source parameters, such as scalar seismic moments, moment magnitudes, double-couple (DC) components and compensated-linear-vector-dipole (CLVD) components, are determined as well as fault parameters and stress-axis parameters. The inverted results are evaluated by groups of numerical tests. 展开更多
关键词 capital Region small-moderate size earthquakes moment tensor inversion
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