Introduction: Primary cutaneous apocrine carcinoma (PCAC) is a rare skin malignant tumor that originates from areas with a high concentration of apocrine glands. The incidence of PCAC in the neck is relatively low. Th...Introduction: Primary cutaneous apocrine carcinoma (PCAC) is a rare skin malignant tumor that originates from areas with a high concentration of apocrine glands. The incidence of PCAC in the neck is relatively low. The age of onset in PCAC ranges from 5 to 70 years old. Clinically, PCAC typically shows up as painless nodules or lumps. In immunohistochemistry, positive expression of CK-7, GCDFP-15, AR, and myoepithelial markers are helpful in the diagnosis of PCAC. This case report pertains to a 59-year-old male of Asian descent. Five years ago, a painless mass was discovered behind his right ear, which grew slowly. This patient was identified as PCAC based on clinical symptoms, pathology, immunohistochemistry, and imaging characteristics. PCAC involved the parotid gland in this case;it is easy to be misdiagnosed as a primary malignant tumor of the parotid gland on imaging. Furthermore, a thorough set of clinical, imaging, pathological, and immunohistochemical examinations must be performed to make a diagnosis because it is challenging to differentiate PCAC from metastatic breast carcinoma. Conclusion: A well-developed multidisciplinary examination is essential because PCAC can be challenging to diagnose and differentiate.展开更多
THYMIC carcinoma is a rare malignant tumor, but the most common malignant tumor of the ante-rior mediastinum. According to the latest World Health Organization （WHO） classification, primary thymic carcinoma has a va...THYMIC carcinoma is a rare malignant tumor, but the most common malignant tumor of the ante-rior mediastinum. According to the latest World Health Organization （WHO） classification, primary thymic carcinoma has a variety of histological types, mainly including squamous cell, basaloid, mucoepidermoid,lymphoepithelioma-like, sarcomatoid, clear cell and neuro-endocrine carcinomas, and papillary adenocarcinoma.1-4 Thymic mucinous adenocarcinoma was discovered in re-cent years, and only 10 cases were reported. In this paper, we described a case of thymic mucinous adenocarcinoma, the histopathological findings and immunohistochemical results.展开更多
目的原发性卵巢黏液性癌在卵巢上皮性癌中相对罕见。本研究探讨原发性卵巢黏液性癌临床特点和预后因素,为临床的治疗提供依据。方法回顾性分析2000-01-01—2013-01-01安徽医科大学附属省立医院收治的33例原发性卵巢黏液性癌患者临床资料...目的原发性卵巢黏液性癌在卵巢上皮性癌中相对罕见。本研究探讨原发性卵巢黏液性癌临床特点和预后因素,为临床的治疗提供依据。方法回顾性分析2000-01-01—2013-01-01安徽医科大学附属省立医院收治的33例原发性卵巢黏液性癌患者临床资料,对其治疗情况进行总结并分析其预后。采用SPSS 17.0中Kaplan-Meier方法计算生存率,应用Log-rank法检验组间生存率差异;采用Cox风险比例回归模型进行多因素分析,筛选出影响患者预后的独立危险因素。结果 33例患者5年生存率为39.39%(13/33)。单因素分析结果显示,国际妇产科协会(Federation International of Gynecology and obstetrics,FIGO)分期、组织分化程度、减瘤术是否满意、是否合并大量腹水、化疗是否满周期以及淋巴结转移状态为影响患者5年生存率的危险因素,均P<0.05;年龄、肿瘤生长部位、原发肿瘤直径、化疗方案、术前CA125是否正常以及术前CA199是否正常对预后无影响,均P>0.05。多因素分析结果显示,FIGO分期、减瘤术是否满意以及化疗是否满周期为影响患者5年生存率的独立危险因素,均P<0.05。结论 FIGO分期较早、减瘤术满意及化疗满周期能明显改善原发性卵巢黏液性癌患者的预后,因此早诊断、早治疗及术后辅以正规足周期的化疗是提高原发性卵巢黏液性癌生存率的关键。展开更多
文摘Introduction: Primary cutaneous apocrine carcinoma (PCAC) is a rare skin malignant tumor that originates from areas with a high concentration of apocrine glands. The incidence of PCAC in the neck is relatively low. The age of onset in PCAC ranges from 5 to 70 years old. Clinically, PCAC typically shows up as painless nodules or lumps. In immunohistochemistry, positive expression of CK-7, GCDFP-15, AR, and myoepithelial markers are helpful in the diagnosis of PCAC. This case report pertains to a 59-year-old male of Asian descent. Five years ago, a painless mass was discovered behind his right ear, which grew slowly. This patient was identified as PCAC based on clinical symptoms, pathology, immunohistochemistry, and imaging characteristics. PCAC involved the parotid gland in this case;it is easy to be misdiagnosed as a primary malignant tumor of the parotid gland on imaging. Furthermore, a thorough set of clinical, imaging, pathological, and immunohistochemical examinations must be performed to make a diagnosis because it is challenging to differentiate PCAC from metastatic breast carcinoma. Conclusion: A well-developed multidisciplinary examination is essential because PCAC can be challenging to diagnose and differentiate.
文摘THYMIC carcinoma is a rare malignant tumor, but the most common malignant tumor of the ante-rior mediastinum. According to the latest World Health Organization （WHO） classification, primary thymic carcinoma has a variety of histological types, mainly including squamous cell, basaloid, mucoepidermoid,lymphoepithelioma-like, sarcomatoid, clear cell and neuro-endocrine carcinomas, and papillary adenocarcinoma.1-4 Thymic mucinous adenocarcinoma was discovered in re-cent years, and only 10 cases were reported. In this paper, we described a case of thymic mucinous adenocarcinoma, the histopathological findings and immunohistochemical results.
文摘目的原发性卵巢黏液性癌在卵巢上皮性癌中相对罕见。本研究探讨原发性卵巢黏液性癌临床特点和预后因素,为临床的治疗提供依据。方法回顾性分析2000-01-01—2013-01-01安徽医科大学附属省立医院收治的33例原发性卵巢黏液性癌患者临床资料,对其治疗情况进行总结并分析其预后。采用SPSS 17.0中Kaplan-Meier方法计算生存率,应用Log-rank法检验组间生存率差异;采用Cox风险比例回归模型进行多因素分析,筛选出影响患者预后的独立危险因素。结果 33例患者5年生存率为39.39%(13/33)。单因素分析结果显示,国际妇产科协会(Federation International of Gynecology and obstetrics,FIGO)分期、组织分化程度、减瘤术是否满意、是否合并大量腹水、化疗是否满周期以及淋巴结转移状态为影响患者5年生存率的危险因素,均P<0.05;年龄、肿瘤生长部位、原发肿瘤直径、化疗方案、术前CA125是否正常以及术前CA199是否正常对预后无影响,均P>0.05。多因素分析结果显示,FIGO分期、减瘤术是否满意以及化疗是否满周期为影响患者5年生存率的独立危险因素,均P<0.05。结论 FIGO分期较早、减瘤术满意及化疗满周期能明显改善原发性卵巢黏液性癌患者的预后,因此早诊断、早治疗及术后辅以正规足周期的化疗是提高原发性卵巢黏液性癌生存率的关键。
