The issue of privacy protection for mobile social networks is a frontier topic in the field of social network applications.The existing researches on user privacy protection in mobile social network mainly focus on pr...The issue of privacy protection for mobile social networks is a frontier topic in the field of social network applications.The existing researches on user privacy protection in mobile social network mainly focus on privacy preserving data publishing and access control.There is little research on the association of user privacy information,so it is not easy to design personalized privacy protection strategy,but also increase the complexity of user privacy settings.Therefore,this paper concentrates on the association of user privacy information taking big data analysis tools,so as to provide data support for personalized privacy protection strategy design.展开更多
Background:The purpose of this study was to identify the characteristics and principles of acupoints applied for treating chronic hepatitis B infection.Methods:The published clinical studies on acupuncture for the tre...Background:The purpose of this study was to identify the characteristics and principles of acupoints applied for treating chronic hepatitis B infection.Methods:The published clinical studies on acupuncture for the treatment of chronic hepatitis B infection were gathered from various databases,including SinoMed,Chongqing Vip,China National Knowledge Infrastructure,Wanfang,the Cochrane Library,PubMed,Web of Science and Embase.Excel 2019 was utilized to establish a database of acupuncture prescriptions and conduct statistics on the frequency,meridian application,distribution and specific points,as well as SPSS Modeler 18.0 and SPSS Statistics 26.0 to conduct association rule analysis and cluster analysis to investigate the characteristics and patterns of acupoint selection.Results:A total of 42 studies containing 47 acupoints were included,with a total frequency of 286 acupoints.The top five acupoints used were Zusanli(ST36),Ganshu(BL18),Yanglingquan(GB34),Sanyinjiao(SP6)and Taichong(LR3),and the most commonly used meridians was the Bladder Meridian of Foot-Taiyang.The majority of acupuncture points are located in the lower limbs,back,and lumbar regions,with a significant percentage of them being Five-Shu acupoints.The strongest acupoint combination identified was Zusanli(ST36)–Ganshu(BL18),in addition to which 13 association rules and 4 valid clusters were obtained.Conclusion:Zusanli(ST36)–Ganshu(BL18)could be considered a relatively reasonable prescription for treating chronic hepatitis B infection in clinical practice.However,further high-quality studies are needed.展开更多
In order to discover the main causes of elevator group accidents in edge computing environment, a multi-dimensional data model of elevator accident data is established by using data cube technology, proposing and impl...In order to discover the main causes of elevator group accidents in edge computing environment, a multi-dimensional data model of elevator accident data is established by using data cube technology, proposing and implementing a method by combining classical Apriori algorithm with the model, digging out frequent items of elevator accident data to explore the main reasons for the occurrence of elevator accidents. In addition, a collaborative edge model of elevator accidents is set to achieve data sharing, making it possible to check the detail of each cause to confirm the causes of elevator accidents. Lastly the association rules are applied to find the law of elevator Accidents.展开更多
Extracting objects from legacy systems is a basic step in system's object orientation to improve the maintainability and understandability of the systems. A new object extraction model using association rules and...Extracting objects from legacy systems is a basic step in system's object orientation to improve the maintainability and understandability of the systems. A new object extraction model using association rules and dependence analysis is proposed. In this model data are classified by association rules and the corresponding operations are partitioned by dependence analysis.展开更多
Based upon a multisensor sequential processing filter, the target states in a3D Cartesian system are projected into the measurement space of each sensor to extend thejoint probabilistic data association (JPDA) algorit...Based upon a multisensor sequential processing filter, the target states in a3D Cartesian system are projected into the measurement space of each sensor to extend thejoint probabilistic data association (JPDA) algorithm into the multisensor tracking systemsconsisting of heterogeneous sensors for the data association.展开更多
Association rule mining methods, as a set of important data mining tools, could be used for mining spatial association rules of spatial data. However, applications of these methods are limited for mining results conta...Association rule mining methods, as a set of important data mining tools, could be used for mining spatial association rules of spatial data. However, applications of these methods are limited for mining results containing large number of redundant rules. In this paper, a new method named Geo-Filtered Association Rules Mining(GFARM) is proposed to effectively eliminate the redundant rules. An application of GFARM is performed as a case study in which association rules are discovered between building land distribution and potential driving factors in Wuhan, China from 1995 to 2015. Ten sets of regular sampling grids with different sizes are used for detecting the influence of multi-scales on GFARM. Results show that the proposed method can filter 50%–70% of redundant rules. GFARM is also successful in discovering spatial association pattern between building land distribution and driving factors.展开更多
Exploration of artworks is enjoyable but often time consuming.For example,it is not always easy to discover the favorite types of unknown painting works.It is not also always easy to explore unpopular painting works w...Exploration of artworks is enjoyable but often time consuming.For example,it is not always easy to discover the favorite types of unknown painting works.It is not also always easy to explore unpopular painting works which looks similar to painting works created by famous artists.This paper presents a painting image browser which assists the explorative discovery of user-interested painting works.The presented browser applies a new multidimensional data visualization technique that highlights particular ranges of particular numeric values based on association rules to suggest cues to find favorite painting images.This study assumes a large number of painting images are provided where categorical information(e.g.,names of artists,created year)is assigned to the images.The presented system firstly calculates the feature values of the images as a preprocessing step.Then the browser visualizes the multidimensional feature values as a heatmap and highlights association rules discovered from the relationships between the feature values and categorical information.This mechanism enables users to explore favorite painting images or painting images that look similar to famous painting works.Our case study and user evaluation demonstrates the effectiveness of the presented image browser.展开更多
HA (hashing array), a new algorithm, for mining frequent itemsets of large database is proposed. It employs a structure hash array, ltemArray ( ) to store the information of database and then uses it instead of da...HA (hashing array), a new algorithm, for mining frequent itemsets of large database is proposed. It employs a structure hash array, ltemArray ( ) to store the information of database and then uses it instead of database in later iteration. By this improvement, only twice scanning of the whole database is necessary, thereby the computational cost can be reduced significantly. To overcome the performance bottleneck of frequent 2-itemsets mining, a modified algorithm of HA, DHA (directaddressing hashing and array) is proposed, which combines HA with direct-addressing hashing technique. The new hybrid algorithm, DHA, not only overcomes the performance bottleneck but also inherits the advantages of HA. Extensive simulations are conducted in this paper to evaluate the performance of the proposed new algorithm, and the results prove the new algorithm is more efficient and reasonable.展开更多
Photometric observations of AH Cnc, a W UMa-type system in the open cluster M67, were car- fled out by using the 50BIN telescope. About 100h of time-series/3- and V-band data were taken, based on which eight new times...Photometric observations of AH Cnc, a W UMa-type system in the open cluster M67, were car- fled out by using the 50BIN telescope. About 100h of time-series/3- and V-band data were taken, based on which eight new times of light minima were determined. By applying the Wilson-Devinney method, the light curves were modeled and a revised photometric solution of the binary system was derived. We con- firmed that AH Cnc is a deep contact (f = 51%), low mass-ratio (q - 0.156) system. Adopting the distance modulus derived from study of the host cluster, we have re-calculated the physical parameters of the binary system, namely the masses and radii. The masses and radii of the two components were estimated to be respectively 1.188(4-0.061) Me, 1.332(4-0.063) RQ for the primary component and 0.185(4-0.032) Me, 0.592(4-0.051) Re for the secondary. By adding the newly derived minimum timings to all the available data, the period variations of AH Cnc were studied. This shows that the orbital period of the binary is con- tinuously increasing at a rate of dp/dt = 4.29 x 10-10 d yr-1. In addition to the long-term period increase, a cyclic variation with a period of 35.26 yr was determined, which could be attributed to an unresolved tertiary component of the system.展开更多
基于SQL Server Analysis Services(简称SSAS)提供的Microsoft关联规则挖掘算法和事务数据挖掘功能,通过利用Arc GIS软件、空间数据库引擎Arc SDE和数据库SQL Server软件,提出了一种新的土地地类关系挖掘实现方案。首先结合空间数据挖掘...基于SQL Server Analysis Services(简称SSAS)提供的Microsoft关联规则挖掘算法和事务数据挖掘功能,通过利用Arc GIS软件、空间数据库引擎Arc SDE和数据库SQL Server软件,提出了一种新的土地地类关系挖掘实现方案。首先结合空间数据挖掘(Spatial Data Mining,SDM)相关技术方法,以土地利用数据库为基础,实现空间数据提取;然后通过空间关联操作将空间信息转化为事务,最后在SSAS中创建多维数据集,完成相关数据挖掘任务。基于某市实例土地利用数据库,采用该方法探测相邻地类间的隐含关系,通过建立相邻地类图斑空间关联规则挖掘模型,设置不同的参数,得到了一系列比较实用合理的关联规则,通过实践证明了这种方案的有效性。展开更多
These days, health care systems such as pharmacies and drugstores normally produce high volumes of data. Consequently, utilizing data mining methods in health care systems has become a conventional process. In this re...These days, health care systems such as pharmacies and drugstores normally produce high volumes of data. Consequently, utilizing data mining methods in health care systems has become a conventional process. In this research, Apriori algorithm has been applied to perform data mining using the data obtained from the prescriptions ordered within a pharmacy. Ten association rules were achieved from the assigned pharmaceutical drugs in those prescriptions using the aforementioned Apriori algorithm. The accuracy of these rules is also manually studied and reviewed by a physician. Among these association rules, Vitamin D and Calcium pills are the most interrelated medications, and Omeprazole and Metronidazole rankd second in terms of association. The results of this study provide useful feedback information about associations among drugs.展开更多
Objective: To analyze the prescription law of TCM compound in the treatment of new coronavirus pneumonia, and provides reference for the clinical treatment of new coronavirus pneumonia. Methods: Collected Collected 24...Objective: To analyze the prescription law of TCM compound in the treatment of new coronavirus pneumonia, and provides reference for the clinical treatment of new coronavirus pneumonia. Methods: Collected Collected 24 novel coronavirus pneumonia related diagnostic and therapeutic plans issued by the National Health Council and the Chinese medicine authority from January 26, 2020 to March 8th ,the filtered solution involved in the formula, establishing database of traditional Chinese medicine compound prescription for the treatment of new crown pneumonia, the frequency of using frequency analysis methods of analysis and clustering analysis and association rules analysis to sort out data mining analysis of traditional Chinese medicine compound. Results: In this study, a total of 159 TCM compounds were included in the treatment of new crown pneumonia from the country and 23 provinces, municipalities and autonomous regions, involving 189 TCM compounds. A total of 62 high-frequency traditional Chinese medicines (frequency ≥ 11) were obtained, mainly including licorice, almond, ephedra, gypsum, Poria cocos, Huoxiang, etc The drug types are mainly heat-clearing drugs, vacuous drugs, moisture-curing drugs, and surfactant drugs. The main effect of the medicine was warm, cold, lukewarm and flat, the main effect of the medicine was bitter and bitter, and the main effect of the medicine was the lung, stomach and spleen. Cluster analysis results according to the performance of traditional Chinese medicine treatment of new crown pneumonia high frequency drugs into 7 classes;Association rule analysis results in 29 common drug pairs. Conclusion: In the treatment of pneumonia caused by new coronavirus infection with traditional Chinese medicine, the following characteristics are presented: the number of times of supplementing qi and Yin is more than that of attacking evil and maintaining health;The method of dispersing and solving the attack of wet, beneficial, wet, permeable and wet medicine fully embodies a variety of ways to drive away evil;In terms of drugs, heat-clearing drugs, deficiency drugs, dampness drugs and surface drugs are the main ones, highlighting that the basic treatment method is to dissolve dampness and detoxify, and replenish qi and Yin. In summary, this study can provide reference for guiding clinical drug use and developing new drugs.展开更多
Objective Based on intra-set correlation analysis, this paper deconstructs the clinical medical records of traditional Chinese medicine(TCM) Master ZHOU Zhongying in treating thyroid cancer, and analyzes the experienc...Objective Based on intra-set correlation analysis, this paper deconstructs the clinical medical records of traditional Chinese medicine(TCM) Master ZHOU Zhongying in treating thyroid cancer, and analyzes the experience in “mechanism-syndrome-medicine-prescription” for thyroid cancer.Methods Through Medcase data processing platform, based on Frequent Pattern(FP)-Growth enhanced correlation analysis algorithm, the medical records of Professor ZHOU Zhongying for the treatment of thyroid cancer from June 1, 2001 to February 28, 2015 were analyzed within the set.Results This study involved 43 medical records, 43 patients, and 167 visits. After processing intra-set correlations, 28 groups of highly correlated symptoms, 21 groups of highly correlated tongue images, 10 groups of highly correlated pulse conditions, 28 groups of highly correlated pathogenesis, 34 groups of highly correlated herbs, and 26 groups of highly correlated western medicine diagnosis were selected. Professor ZHOU Zhongying treats thyroid cancer according to syndrome differentiation. Symptoms with more association rules included neck swelling, neck pain, cough, and dry mouth;tongue images with more association rules included dark purple tongue, dark red tongue, and fissured tongue;pulse conditions with more association rules were wiry pulse, thready pulse, small pulse, and slippery pulse;the pathogenesis with more association rules was phlegm and blood stasis, damp-heat accumulation,and impairment of both Qi and Yin;herbs with more association rules were Chaihu(Bupleuri Radix), Zeqi(Sun Euphoribiae Herb), and Tiandong(Asparagi Radix);western medicine diagnosis with more association rules included thyroid cancer, insomnia, and chronic gastritis.Conclusion Thyroid cancer mostly presents as deficiency in origin and excess in manifestations. The basic pathogenesis is phlegm and blood stasis, damp-heat accumulation, and impairment of both Qi and Yin, which are closely related to liver, kidney, and spleen. Professor ZHOU Zhongying adopts both attack and supplement approaches as the general treatment principle, with a strong emphasis on regulating Qi and relieving depression, eliminating phlegm and resolving stagnation, eliminating dampness and turbidity, clearing fire and destroying poison, moistening dryness and softening hard mass, invigorating Qi and nourishing Yin, and paying attention to nourishing liver and kidney, invigorating spleen and stomach,while protecting the heart and lungs.展开更多
Data exploration,usually the first step in data analysis,is a useful method to tackle challenges caused by big geoscience data.It conducts quick analysis of data,investigates the patterns,and generates/refines researc...Data exploration,usually the first step in data analysis,is a useful method to tackle challenges caused by big geoscience data.It conducts quick analysis of data,investigates the patterns,and generates/refines research questions to guide advanced statistics and machine learning algorithms.The background of this work is the open mineral data provided by several sources,and the focus is different types of associations in mineral properties and occurrences.Researchers in mineralogy have been applying different techniques for exploring such associations.Although the explored associations can lead to new scientific insights that contribute to crystallography,mineralogy,and geochemistry,the exploration process is often daunting due to the wide range and complexity of factors involved.In this study,our purpose is implementing a visualization tool based on the adjacency matrix for a variety of datasets and testing its utility for quick exploration of association patterns in mineral data.Algorithms,software packages,and use cases have been developed to process a variety of mineral data.The results demonstrate the efficiency of adjacency matrix in real-world usage.All the developed works of this study are open source and open access.展开更多
基金We thank the anonymous reviewers and editors for their very constructive comments.the National Social Science Foundation Project of China under Grant 16BTQ085.
文摘The issue of privacy protection for mobile social networks is a frontier topic in the field of social network applications.The existing researches on user privacy protection in mobile social network mainly focus on privacy preserving data publishing and access control.There is little research on the association of user privacy information,so it is not easy to design personalized privacy protection strategy,but also increase the complexity of user privacy settings.Therefore,this paper concentrates on the association of user privacy information taking big data analysis tools,so as to provide data support for personalized privacy protection strategy design.
基金supported by Chongqing Municipal Health and Family Planning Commission and Chongqing Municipal Science and Technology Commission Jointly Funded Key Research Projects in Traditional Chinese Medicine(ZY201801007).
文摘Background:The purpose of this study was to identify the characteristics and principles of acupoints applied for treating chronic hepatitis B infection.Methods:The published clinical studies on acupuncture for the treatment of chronic hepatitis B infection were gathered from various databases,including SinoMed,Chongqing Vip,China National Knowledge Infrastructure,Wanfang,the Cochrane Library,PubMed,Web of Science and Embase.Excel 2019 was utilized to establish a database of acupuncture prescriptions and conduct statistics on the frequency,meridian application,distribution and specific points,as well as SPSS Modeler 18.0 and SPSS Statistics 26.0 to conduct association rule analysis and cluster analysis to investigate the characteristics and patterns of acupoint selection.Results:A total of 42 studies containing 47 acupoints were included,with a total frequency of 286 acupoints.The top five acupoints used were Zusanli(ST36),Ganshu(BL18),Yanglingquan(GB34),Sanyinjiao(SP6)and Taichong(LR3),and the most commonly used meridians was the Bladder Meridian of Foot-Taiyang.The majority of acupuncture points are located in the lower limbs,back,and lumbar regions,with a significant percentage of them being Five-Shu acupoints.The strongest acupoint combination identified was Zusanli(ST36)–Ganshu(BL18),in addition to which 13 association rules and 4 valid clusters were obtained.Conclusion:Zusanli(ST36)–Ganshu(BL18)could be considered a relatively reasonable prescription for treating chronic hepatitis B infection in clinical practice.However,further high-quality studies are needed.
文摘In order to discover the main causes of elevator group accidents in edge computing environment, a multi-dimensional data model of elevator accident data is established by using data cube technology, proposing and implementing a method by combining classical Apriori algorithm with the model, digging out frequent items of elevator accident data to explore the main reasons for the occurrence of elevator accidents. In addition, a collaborative edge model of elevator accidents is set to achieve data sharing, making it possible to check the detail of each cause to confirm the causes of elevator accidents. Lastly the association rules are applied to find the law of elevator Accidents.
基金Supported in part by the National Natural Science F oundation of China(6 0 0 730 12 )
文摘Extracting objects from legacy systems is a basic step in system's object orientation to improve the maintainability and understandability of the systems. A new object extraction model using association rules and dependence analysis is proposed. In this model data are classified by association rules and the corresponding operations are partitioned by dependence analysis.
文摘Based upon a multisensor sequential processing filter, the target states in a3D Cartesian system are projected into the measurement space of each sensor to extend thejoint probabilistic data association (JPDA) algorithm into the multisensor tracking systemsconsisting of heterogeneous sensors for the data association.
基金Under the auspices of Special Fund of Ministry of Land and Resources of China in Public Interest(No.201511001)
文摘Association rule mining methods, as a set of important data mining tools, could be used for mining spatial association rules of spatial data. However, applications of these methods are limited for mining results containing large number of redundant rules. In this paper, a new method named Geo-Filtered Association Rules Mining(GFARM) is proposed to effectively eliminate the redundant rules. An application of GFARM is performed as a case study in which association rules are discovered between building land distribution and potential driving factors in Wuhan, China from 1995 to 2015. Ten sets of regular sampling grids with different sizes are used for detecting the influence of multi-scales on GFARM. Results show that the proposed method can filter 50%–70% of redundant rules. GFARM is also successful in discovering spatial association pattern between building land distribution and driving factors.
文摘Exploration of artworks is enjoyable but often time consuming.For example,it is not always easy to discover the favorite types of unknown painting works.It is not also always easy to explore unpopular painting works which looks similar to painting works created by famous artists.This paper presents a painting image browser which assists the explorative discovery of user-interested painting works.The presented browser applies a new multidimensional data visualization technique that highlights particular ranges of particular numeric values based on association rules to suggest cues to find favorite painting images.This study assumes a large number of painting images are provided where categorical information(e.g.,names of artists,created year)is assigned to the images.The presented system firstly calculates the feature values of the images as a preprocessing step.Then the browser visualizes the multidimensional feature values as a heatmap and highlights association rules discovered from the relationships between the feature values and categorical information.This mechanism enables users to explore favorite painting images or painting images that look similar to famous painting works.Our case study and user evaluation demonstrates the effectiveness of the presented image browser.
文摘HA (hashing array), a new algorithm, for mining frequent itemsets of large database is proposed. It employs a structure hash array, ltemArray ( ) to store the information of database and then uses it instead of database in later iteration. By this improvement, only twice scanning of the whole database is necessary, thereby the computational cost can be reduced significantly. To overcome the performance bottleneck of frequent 2-itemsets mining, a modified algorithm of HA, DHA (directaddressing hashing and array) is proposed, which combines HA with direct-addressing hashing technique. The new hybrid algorithm, DHA, not only overcomes the performance bottleneck but also inherits the advantages of HA. Extensive simulations are conducted in this paper to evaluate the performance of the proposed new algorithm, and the results prove the new algorithm is more efficient and reasonable.
基金supported by the National Natural Science Foundation of China(Nos. U1131121,11303021,U1231202,11473037 and 11373073)
文摘Photometric observations of AH Cnc, a W UMa-type system in the open cluster M67, were car- fled out by using the 50BIN telescope. About 100h of time-series/3- and V-band data were taken, based on which eight new times of light minima were determined. By applying the Wilson-Devinney method, the light curves were modeled and a revised photometric solution of the binary system was derived. We con- firmed that AH Cnc is a deep contact (f = 51%), low mass-ratio (q - 0.156) system. Adopting the distance modulus derived from study of the host cluster, we have re-calculated the physical parameters of the binary system, namely the masses and radii. The masses and radii of the two components were estimated to be respectively 1.188(4-0.061) Me, 1.332(4-0.063) RQ for the primary component and 0.185(4-0.032) Me, 0.592(4-0.051) Re for the secondary. By adding the newly derived minimum timings to all the available data, the period variations of AH Cnc were studied. This shows that the orbital period of the binary is con- tinuously increasing at a rate of dp/dt = 4.29 x 10-10 d yr-1. In addition to the long-term period increase, a cyclic variation with a period of 35.26 yr was determined, which could be attributed to an unresolved tertiary component of the system.
文摘基于SQL Server Analysis Services(简称SSAS)提供的Microsoft关联规则挖掘算法和事务数据挖掘功能,通过利用Arc GIS软件、空间数据库引擎Arc SDE和数据库SQL Server软件,提出了一种新的土地地类关系挖掘实现方案。首先结合空间数据挖掘(Spatial Data Mining,SDM)相关技术方法,以土地利用数据库为基础,实现空间数据提取;然后通过空间关联操作将空间信息转化为事务,最后在SSAS中创建多维数据集,完成相关数据挖掘任务。基于某市实例土地利用数据库,采用该方法探测相邻地类间的隐含关系,通过建立相邻地类图斑空间关联规则挖掘模型,设置不同的参数,得到了一系列比较实用合理的关联规则,通过实践证明了这种方案的有效性。
文摘These days, health care systems such as pharmacies and drugstores normally produce high volumes of data. Consequently, utilizing data mining methods in health care systems has become a conventional process. In this research, Apriori algorithm has been applied to perform data mining using the data obtained from the prescriptions ordered within a pharmacy. Ten association rules were achieved from the assigned pharmaceutical drugs in those prescriptions using the aforementioned Apriori algorithm. The accuracy of these rules is also manually studied and reviewed by a physician. Among these association rules, Vitamin D and Calcium pills are the most interrelated medications, and Omeprazole and Metronidazole rankd second in terms of association. The results of this study provide useful feedback information about associations among drugs.
基金High level innovation and entrepreneurship team of Liaoning Province(No.XLYC1808011)
文摘Objective: To analyze the prescription law of TCM compound in the treatment of new coronavirus pneumonia, and provides reference for the clinical treatment of new coronavirus pneumonia. Methods: Collected Collected 24 novel coronavirus pneumonia related diagnostic and therapeutic plans issued by the National Health Council and the Chinese medicine authority from January 26, 2020 to March 8th ,the filtered solution involved in the formula, establishing database of traditional Chinese medicine compound prescription for the treatment of new crown pneumonia, the frequency of using frequency analysis methods of analysis and clustering analysis and association rules analysis to sort out data mining analysis of traditional Chinese medicine compound. Results: In this study, a total of 159 TCM compounds were included in the treatment of new crown pneumonia from the country and 23 provinces, municipalities and autonomous regions, involving 189 TCM compounds. A total of 62 high-frequency traditional Chinese medicines (frequency ≥ 11) were obtained, mainly including licorice, almond, ephedra, gypsum, Poria cocos, Huoxiang, etc The drug types are mainly heat-clearing drugs, vacuous drugs, moisture-curing drugs, and surfactant drugs. The main effect of the medicine was warm, cold, lukewarm and flat, the main effect of the medicine was bitter and bitter, and the main effect of the medicine was the lung, stomach and spleen. Cluster analysis results according to the performance of traditional Chinese medicine treatment of new crown pneumonia high frequency drugs into 7 classes;Association rule analysis results in 29 common drug pairs. Conclusion: In the treatment of pneumonia caused by new coronavirus infection with traditional Chinese medicine, the following characteristics are presented: the number of times of supplementing qi and Yin is more than that of attacking evil and maintaining health;The method of dispersing and solving the attack of wet, beneficial, wet, permeable and wet medicine fully embodies a variety of ways to drive away evil;In terms of drugs, heat-clearing drugs, deficiency drugs, dampness drugs and surface drugs are the main ones, highlighting that the basic treatment method is to dissolve dampness and detoxify, and replenish qi and Yin. In summary, this study can provide reference for guiding clinical drug use and developing new drugs.
基金Six Talent Peak Projects in Jiangsu Province (RJFW-40)Jiangsu Province “333 High-level Talent Training Project”(2018Ⅲ-0121)+2 种基金Technology Innovation Fund of Science and Technology Enterprises in Jiangsu Province (BC2015022)Representative Project of Intangible Cultural Heritage in Pukou District,Nanjing (PKIX-4)The Construction and Application of Thyroid Disease Differentiation and Treatment Rule Mining and Clinical Decision Support System by Traditional Chinese Medicine Master ZHOU Zhongying (012071003583)。
文摘Objective Based on intra-set correlation analysis, this paper deconstructs the clinical medical records of traditional Chinese medicine(TCM) Master ZHOU Zhongying in treating thyroid cancer, and analyzes the experience in “mechanism-syndrome-medicine-prescription” for thyroid cancer.Methods Through Medcase data processing platform, based on Frequent Pattern(FP)-Growth enhanced correlation analysis algorithm, the medical records of Professor ZHOU Zhongying for the treatment of thyroid cancer from June 1, 2001 to February 28, 2015 were analyzed within the set.Results This study involved 43 medical records, 43 patients, and 167 visits. After processing intra-set correlations, 28 groups of highly correlated symptoms, 21 groups of highly correlated tongue images, 10 groups of highly correlated pulse conditions, 28 groups of highly correlated pathogenesis, 34 groups of highly correlated herbs, and 26 groups of highly correlated western medicine diagnosis were selected. Professor ZHOU Zhongying treats thyroid cancer according to syndrome differentiation. Symptoms with more association rules included neck swelling, neck pain, cough, and dry mouth;tongue images with more association rules included dark purple tongue, dark red tongue, and fissured tongue;pulse conditions with more association rules were wiry pulse, thready pulse, small pulse, and slippery pulse;the pathogenesis with more association rules was phlegm and blood stasis, damp-heat accumulation,and impairment of both Qi and Yin;herbs with more association rules were Chaihu(Bupleuri Radix), Zeqi(Sun Euphoribiae Herb), and Tiandong(Asparagi Radix);western medicine diagnosis with more association rules included thyroid cancer, insomnia, and chronic gastritis.Conclusion Thyroid cancer mostly presents as deficiency in origin and excess in manifestations. The basic pathogenesis is phlegm and blood stasis, damp-heat accumulation, and impairment of both Qi and Yin, which are closely related to liver, kidney, and spleen. Professor ZHOU Zhongying adopts both attack and supplement approaches as the general treatment principle, with a strong emphasis on regulating Qi and relieving depression, eliminating phlegm and resolving stagnation, eliminating dampness and turbidity, clearing fire and destroying poison, moistening dryness and softening hard mass, invigorating Qi and nourishing Yin, and paying attention to nourishing liver and kidney, invigorating spleen and stomach,while protecting the heart and lungs.
基金supported by the U.S.National Science Foundation(Grant No.2126315).
文摘Data exploration,usually the first step in data analysis,is a useful method to tackle challenges caused by big geoscience data.It conducts quick analysis of data,investigates the patterns,and generates/refines research questions to guide advanced statistics and machine learning algorithms.The background of this work is the open mineral data provided by several sources,and the focus is different types of associations in mineral properties and occurrences.Researchers in mineralogy have been applying different techniques for exploring such associations.Although the explored associations can lead to new scientific insights that contribute to crystallography,mineralogy,and geochemistry,the exploration process is often daunting due to the wide range and complexity of factors involved.In this study,our purpose is implementing a visualization tool based on the adjacency matrix for a variety of datasets and testing its utility for quick exploration of association patterns in mineral data.Algorithms,software packages,and use cases have been developed to process a variety of mineral data.The results demonstrate the efficiency of adjacency matrix in real-world usage.All the developed works of this study are open source and open access.