Analysis of Renewable Energy Absorption and Economic Feasibility in Multi-Energy Complementary Systems under Spot Market Conditions

As the power system transitions to a new green and low-carbon paradigm,the penetration of renewable energy in China’s power system is gradually increasing.However,the variability and uncertainty of renewable energy output limit its profitability in the electricity market and hinder its market-based integration.This paper first constructs a wind-solar-thermalmulti-energy complementary system,analyzes its external game relationships,and develops a bi-level market optimization model.Then,it considers the contribution levels of internal participants to establish a comprehensive internal distribution evaluation index system.Finally,simulation studies using the IEEE 30-bus system demonstrate that the multi-energy complementary system stabilizes nodal outputs,enhances the profitability of market participants,and promotes the market-based integration of renewable energy.

Multi-energy synergistic optimization in steelmaking process based on energy hub concept

The production process of iron and steel is accompanied by a large amount of energy production and consumption. Optimal scheduling and utilization of these energies within energy systems are crucial to realize a reduction in the cost, energy use, and CO_2 emissions.However, it is difficult to model and schedule energy usage within steel works because different types of energy and devices are involved. The energy hub(EH), as a universal modeling frame, is widely used in multi-energy systems to improve its efficiency, flexibility, and reliability.This paper proposed an efficient multi-layer model based on the EH concept, which is designed to systematically model the energy system and schedule energy within steelworks to meet the energy demand. Besides, to simulate the actual working conditions of the energy devices, the method of fitting the curve is used to describe the efficiency of the energy devices. Moreover, to evaluate the applicability of the proposed model, a case study is conducted to minimize both the economic operation cost and CO_2 emissions. The optimal results demonstrated that the model is suitable for energy systems within steel works. Further, the economic operation cost decreased by 3.41%, and CO_2 emissions decreased by approximately 3.67%.

基于HubGLasso注意力机制的脑网络分类研究

脑网络分类有助于脑疾病的早期诊断,也有益于理解脑疾病发病机理,具有重要的研究与应用价值。其中,卷积神经网络应用广泛,可以提取脑网络的拓扑特征,是脑网络分类中的一个前沿热点。然而,现有方法未考虑脑网络中Hub节点对脑功能的重要贡献,这可能会导致特征提取不充分,限制了它们的分类性能。为此,该文提出了一种基于HubGLasso注意力机制的卷积神经网络模型,用于进行脑网络分类任务。该方法包含了一种新的卷积层结构,首先利用GLasso模型去除脑网络中的冗余信息,然后引入Hub约束与注意力机制,使其能够提取与异常Hub结构相关的重要特征,并用于脑疾病诊断。实验结果表明,该方法在包含1112个被试的真实自闭症数据集上取得了68.67%的准确率,显著优于目前已有方法,证明了其应用价值。更进一步,通过对训练后的模型进行特征分析,能够得到与脑疾病相关的脑区信息与Hub节点结构信息,为脑疾病病理机制的研究提供了全新的视角。

基于加权基因共表达网络和癌症基因组图谱临床数据分析并鉴定肝细胞癌的Hub基因研究

背景 肝细胞癌(HCC)是全球常见的癌症相关死亡的第三大原因,约占所有原发性肝癌病例的90%,其复发率和死亡率较高,目前发生的分子机制仍不清楚。目的 探索HCC潜在的分子机制,发掘新的生物标志物。方法 从TCGA数据库下载RNA-seq表达数据和临床相关信息,通过差异基因表达分析正常肝脏组织与HCC组织的差异基因;对差异表达基因进行富集分析;基于TCGA中HCC的基因表达数据概况,使用WGCNA R包建立共表达网络,进行加权基因共表达网络分析(WGCNA),选择具有临床意义的模块,并筛选候选Hub基因;进一步分析候选Hub基因在HCC组织和正常肝脏组织显著差异表达、与HCC患者总体生存期和无病生存期是否显著相关,最终确定Hub基因;通过人类蛋白质图谱数据库对Hub基因蛋白表达进行验证。结果 本研究的基因表达数据来自50个正常肝脏组织样本和373个HCC组织样本。通过差异基因表达分析发现7 230个在HCC和正常肝脏组织之间差异表达的基因(HCC中3 691个上调基因和3 539个下调基因)。富集分析表明,上调的差异表达基因主要参与细胞周期调控和有丝分裂过程;下调的差异表达基因主要参与小分子代谢和有机酸代谢等过程。WGCNA确定了19个与HCC患者临床特征相关基因模块,通过分析模块与临床特征之间的关系,筛选出青色模块和紫色模块。青色模块基因中同时与患者总生存期和无病生存期强烈相关的前两个基因为VPS45和FAM189B;紫色模块基因中同时与患者总生存期和无病生存期强烈相关的前两个基因分别为CLEC1B和FCN3,因此将VPS45、FAM189B、CLEC1B和FCN3确定为最终的Hub基因。人类蛋白质图谱数据库免疫组织化学染色显示:VPS45和FAM189B在HCC组织中的表达高于正常肝脏组织,FCN3在HCC组织中的表达低于正常肝脏组织,CLEC1B在HCC组织和正常肝脏组织中表达差异不明显。结论 初步确定VPS45、FAM189B、CLEC1B和FCN3可能是HCC的新型潜在生物标志物,这些Hub基因可能为HCC的靶向治疗提供理论基础。

Identification of hub genes associated with Helicobacter pylori infection and type 2 diabetes mellitus:A pilot bioinformatics study

BACKGROUND Helicobacter pylori(H.pylori)infection is related to various extragastric diseases including type 2 diabetes mellitus(T2DM).However,the possible mechanisms connecting H.pylori infection and T2DM remain unknown.AIM To explore potential molecular connections between H.pylori infection and T2DM.METHODS We extracted gene expression arrays from three online datasets(GSE60427,GSE27411 and GSE115601).Differentially expressed genes(DEGs)commonly present in patients with H.pylori infection and T2DM were identified.Hub genes were validated using human gastric biopsy samples.Correlations between hub genes and immune cell infiltration,miRNAs,and transcription factors(TFs)were further analyzed.RESULTS A total of 67 DEGs were commonly presented in patients with H.pylori infection and T2DM.Five significantly upregulated hub genes,including TLR4,ITGAM,C5AR1,FCER1G,and FCGR2A,were finally identified,all of which are closely related to immune cell infiltration.The gene-miRNA analysis detected 13 miRNAs with at least two gene cross-links.TF-gene interaction networks showed that TLR4 was coregulated by 26 TFs,the largest number of TFs among the 5 hub genes.CONCLUSION We identified five hub genes that may have molecular connections between H.pylori infection and T2DM.This study provides new insights into the pathogenesis of H.pylori-induced onset of T2DM.

无人车载网络高可靠HUB的设计

为满足无人车技术的不断发展及日趋复杂的车载网络带来的高带宽和高可靠性的使用要求,设计一种车载网络集线器(HUB)。采用时间触发协议(TTP),设计时间触发以太网(TTE)加星型TTP总线的架构。TTE提高数据带宽,在物理层与驱动设备采用点对点的连接方式代替总线型通信方式,提高可靠性,解决总线型通信方式一点断开,整体通信失效的问题。针对HUB的设计做详细阐述,通过实验验证了设计的可行性和可靠性,对车载网络的优化提供了可行的解决途径。

应用生物信息学筛选结直肠癌Hub基因及验证

目的通过运用生物信息学分析,筛选出与结直肠癌相关的差异表达基因(Differentially Expressed genes,DEGs),并验证其生物学功能。方法云浮市人民医院检验科从基因表达综合数据库(Gene Expression Omnibus,GEO)中下载结直肠癌芯片数据GSE 21815、GSE 31905、GSE 35279资料,应用GEO2R语言进行处理得出结直肠癌和正常结直肠组织之间的差异表达基因,并通过生物信息学工具DAVID、STRING、Cytoscape构建差异表达基因的蛋白互作网络,筛选Hub基因,应用基因本体论(Gene Ontology,GO)、基因百科全书(Kyoto Encyclopedia of Genes and Genomes,KEGG)分析筛选出的Hub基因的生物功能,并利用MiRDB工具找出可能调控Hub基因的miRNA,并于2017—2022年8月收集30例结直肠癌组织和30例正常结直肠组织样本,通过实时荧光定量PCR(Quantitative Real-time PCR,qPCR)验证。结果经生物学信息分析和蛋白质相互作用网络图分析催产素受体基因、基质金属蛋白酶11基因、间质上皮转化因子基因、基质金属蛋白酶7基因、激肽释放酶8基因、激肽释放酶10基因为结直肠癌组织发生发展的关键Hub基因。结直肠癌组织中基质金属蛋白酶11基因(4.38±1.58)、间质上皮转化因子基因(2.69±0.29)、基质金属蛋白酶7基因(0.88±0.14)、激肽释放酶8基因(11.09±3.90)、激肽释放酶10基因mRNA(7.88±2.20)的表达,显著高于正常结直肠组织组织,差异有统计学意义(t=9.605、25.339、26.376、9.541、3.726,P均<0.001)。结论结直肠癌组织中基质金属蛋白酶11基因、间质上皮转化因子基因、基质金属蛋白酶7基因、激肽释放酶8基因、激肽释放酶10基因异常表达,可能参与结直肠癌发生过程,有望为后续结直肠癌基础研究及临床诊疗提供依据。

Functional investigation and two-sample Mendelian randomization study of primary biliary cholangitis hub genes

BACKGROUND The identification of specific gene expression patterns is crucial for understanding the mechanisms underlying primary biliary cholangitis(PBC)and finding relevant biomarkers for diagnosis and therapeutic evaluation.AIM To determine PBC-associated hub genes and assess their clinical utility for disease prediction.METHODS PBC expression data were obtained from the Gene Expression Omnibus database.Overlapping genes from differential expression analysis and weighted gene coexpression network analysis(WGCNA)were identified as key genes for PBC.Kyoto Encyclopedia of Genes and Genomes and Gene Ontology analyses were performed to explore the potential roles of key genes.Hub genes were identified in protein-protein interaction(PPI)networks using the Degree algorithm in Cytoscape software.The relationship between hub genes and immune cells was investigated.Finally,a Mendelian randomization study was conducted to determine the causal effects of hub genes on PBC.RESULTS We identified 71 overlapping key genes using differential expression analysis and WGCNA.These genes were primarily enriched in pathways related to cytokinecytokine receptor interaction,and Th1,Th2,and Th17 cell differentiation.We utilized Cytoscape software and identified five hub genes(CD247,IL10,CCL5,CCL3,and STAT3)in PPI networks.These hub genes showed a strong correlation with immune cell infiltration in PBC.However,inverse variance weighting analysis did not indicate the causal effects of hub genes on PBC risk.CONCLUSION Hub genes can potentially serve as valuable biomarkers for PBC prediction and treatment,thereby offering significant clinical utility.

A Study on Integrated Construction of Luzhou Comprehensive Transportation Hub

The target of integrated construction of comprehensive transportation hub is to integrate the traffic resources,achieve butt joint of pan-regional transportation mode,and finally realize the"seamless connection"of the goods and"zero transfer"of the passenger traffic.Relying on the particularity of the geographical location and the convenience of the Yangtze River channel,Luzhou puts forth effort to build a comprehensive transport hub in Southern Sichuan and has made great efforts in traffic infrastructure construction.However,there are still some problems.Combining practice of Luzhou,using the advanced experience of foreign and domestic cities for reference,the paper pointed out that for the sake of constructing a comprehensive transportation hub,we need to build the traffic integration on the basis of the efficiency.Besides,the paper proposed the strategies for construction.

Cooling and Optimization in the Groove of the Outer Rotor HubMotor

The external rotor hub motor adopts direct drive mode,no deceleration drive device,and has a compact structure.Its axial size is smaller than that of a deceleration-driven hub motor,which greatly reduces the weight of the vehicle and increases the cruising range of the vehicle.Because of the limited special working environment and performance requirements,the hub motor has a small internal space and a large heat generation,so it puts forward higher requirements for heat dissipation capacity.For the external rotor hub motor,a new type of in-tank watercooled structure of hub motor was proposed to improve its cooling effect and performance.Firstly,the threedimensional finite element model of the motor is established to analyze the characteristics of motor loss and temperature field distribution.Secondly,the cooling performance of different cooling structures in the tank was studied.Finally,the thermal network model and three-dimensional finite element analysis were used to optimize the water-cooled structure in the tank,and the power density of themotor was improved by improving the cooling performance under the condition of volume limitation of the hub motor.The results show that the cooling effect of the proposed water-cooled structure in the tank is significant under the condition of constant power density.Compared to natural ventilation,the maximum temperature was reduced by 33.13°C and the cooling effect was increased by about 27.7%.

Mind+结合XEduHub开发AI交互作品

在图形化编程工具Mind+和通用AI推理库XEdu Hub的支持下,中小学生使用简短的代码就能设计出有趣的AI交互作品。本文在介绍Mind+和XEdu Hub的同时,分析了AI交互作品的核心环节,指出作品可以由感知输入、智能处理和执行呈现三个部分组成,希望为中小学开展AI教育提供新的思路。

Analysis of Roadbed Splicing at Hub Interchanges

This article discusses the roadbed splicing for hub interchanges.The article starts with a description of the characteristics of junction roadbed splicing.The application of splicing technology is explained using a subgrade splicing scheme of a project.Roadbed splicing involves stepwise excavation and preparative measures like surface cleaning and backfilling.This article serves to provide a valuable reference for road and bridge construction and improve the quality of China’s road and bridge projects,so as to achieve sustainable development of the road and bridge engineering industry.

TVU推出媒体信号路由新品MediaHub云调度

近期,TVU推出重磅新品——TVU MediaHub云调度。这一产品采用混合云构架的分布式处理技术,实现了任意地点、任意格式的媒体信号以多种格式传输到多个目的地。TVU MediaHub通过其全能的转换与调度功能,可以实现物理硬件与云端资源的集结,为用户提供一个能够灵活转换和高效调度全格式信号的平台。它采用基于先进微服务技术的架构,构建了一个灵活可靠的媒体信号调度中心,确保与TVU各类终端和系统的无缝集成,实现了输入输出的高效管理。此外,TVU MediaHub还与TVU云导播、云播出等服务实现无缝连接。它还引入了灵活的计费系统,根据用户的实际需求进行计费,从而优化成本。操作方面,TVU MediaHub通过其WebUI界面提供简化的操作流程,用户可以实时预览并通过拖拽信号来完成调度,极大地简化了操作步骤,提高了工作效率。

HMDV可控动惯性悬架优化设计与分数阶滑模控制研究

针对轮毂电机驱动汽车(hub motor driven vehicle,HMDV)因开关磁阻电机自重和电机气隙偏心导致产生的垂向振动负效应严重恶化车辆的平顺性和操稳性的问题,提出一种基于分数阶滑模控制的HMDV可控动惯性悬架优化设计方法。首先,在轮毂驱动电机气隙偏心产生的不平衡径向力基础上,建立HMDV 1/4混棚动惯性悬架,理论证明二阶混棚正实网络的优异性能;其次,采用HMDV二阶混棚正实网络作为参考模型,构建基于分数阶滑模控制理论的HMDV协调控制系统,在随机路面下进行平顺性仿真和分析;最后,进行HMDV 1/4悬架台架试验。试验结果表明,HMDV可控动惯性悬架与HMDV传统被动悬架相比,车身加速度均方根值、悬架动行程均方根值以及轮胎动载荷均方根值最大降幅分别为7.72%、30.64%以及11.54%。验证了所设计的HMDV可控动惯性悬架对于由开关磁阻电机造成的垂向振动负效应有优异的抑制性能。

轮毂轴承单元密封结构优化设计及试验验证

针对轮毂轴承单元密封结构产生的摩擦力矩占比过大的问题,提出了将密封材料由氟橡胶改进为丁腈橡胶,密封结构减少一个接触唇的改进措施,并通过优化得到最优密封中间唇参数为唇倾斜角65°、唇厚0.6 mm、唇长3.8 mm、过盈量0.35 mm。将密封改进后的轮毂轴承单元进行了密封圈应力、漏脂试验、泥浆试验的仿真分析并通过试验进行验证,结果表明,优化后的轴承应力均满足材料许用应力要求,未出现漏脂现象,油脂含水量增加小于3%,启动、动态摩擦力矩分别降低了24.3%,22.1%,证明了优化后密封结构的可靠性。

永磁轮毂电机最优磁链矢量无权重价值函数模型预测转矩控制

永磁轮毂电机的外转子通常与轮辋轮胎直接相联结,相比内转子永磁驱动电机,转动惯量较大,其速度响应明显滞后负载变化。因此,复杂运行工况下,永磁轮毂电机驱动系统转速不稳定,电动车辆行走路径易出现偏移。为解决轮毂驱动下电动车辆的这一固有技术难题,提出一种磁链为唯一约束条件的无权重价值函数模型预测转矩控制(model predictive torque control,MPTC)策略,可实现复杂多变动态工况下电动车辆稳定运行的工作需求。所提价值函数将转矩、定子磁链幅值约束统一为定子磁链矢量的优化,消除了权重系数的整定,提高了复杂运行工况下轮毂电机的反应速度。同时,引入有效电压矢量与零电压矢量切换瞬间的定子磁链,以此为评估依据选择最优电压矢量,可降低转矩与定子磁链脉动,从而提高轮毂电机转速控制精度。实验验证了控制方法的正确性和有效性。

长江文化的历史内涵与现代价值——兼论长江国家文化公园的建构逻辑

长江流域是世界稻作文明的起源地。水稻以其特有的物种属性和经济属性,为中华民族的人口繁衍与文化传承提供了丰厚的物质基础和有利的社会条件。借助于大运河、荆襄古道、金牛道的南北互济以及茶马古道的东西融通,中华文化构建了一套北方与南方、中心与边缘的双循环体系,形成了内源性动力机制。陆上和海上丝绸之路为中华文化汲取外部文明打开了窗口,促进了中西文明的交流互鉴。长江流域作为驱动双循环的核心区域,居功至伟,成为中华民族“历史的地理枢纽”。在新时期建设中华民族现代文明的过程中,长江“历史的地理枢纽”需要转化为“当代地理枢纽”:通过“长江大保护”来恢复生态长江并推动经济长江的高质量发展;以长江国家文化公园的建设,推动长江文明与世界大河文明对话,深化中外文明的交流互鉴。

一种基于网络局域信息的传播阻断方法

[研究目的]为减少有害信息快速扩散造成的负面影响,及时对网络中重要节点实施免疫保护,是一种有效阻断传播的方法。[研究方法]针对多数网络全局信息难以获取或缺失的情况,借助于节点局部结构信息,采用自回避随机游走直接获取网络中桥枢纽节点,以此作为免疫对象实现最优阻断。[研究结果/结论]实验结果表明,相对于熟人免疫以及广泛使用的随机游走算法,新方法具有较高的准确性,同时受感染概率的影响较小,具有很高的稳定性,可以广泛应用于现实网络空间信息防控中。

站城人一体化发展下铁路枢纽功能与客流需求分析

[目的]在站城人一体化发展下,铁路客运枢纽在承担交通功能与城市开发功能的基础上,升级为提供情感联系与寄托的新型城市空间,枢纽的服务属性和承载的客流群体发生较大变化,需立足需求端的变化研究站城人一体化发展下铁路客运枢纽的功能特征和客流需求。[方法]基于站城人一体化发展的阶段性特征及其对铁路枢纽承担客流的影响,分析了新型铁路客运枢纽的功能变化及其承担的客流构成,具体包括基于交通服务的趋势客流、城市开发诱增的衍生客流、供给动态调整的韧性客流等几部分,在传统交通预测四阶段法的基础上提出每种情景客流需求的预测思路及方法,并以西安东站为例进行验证分析。[结果及结论]枢纽客流呈现出交通功能客流前期为主、城市功能客流逐步增长、韧性客流短期趋稳的发展态势。综合三部分客流分析,初步预测西安东枢纽远期高峰小时的客流总量约为3.0万~3.2万人次/h。通过细化枢纽各部分客流需求的预测方法,可为新型枢纽的功能配置、设施布局、客运组织等提供科学可靠的依据。

基于产品开发网络Hub节点的工程变更

为了深入研究工程变更的传播机理,在产品开发网络中扩充了Hub节点的内涵,揭示了Hub节点在变更传播中的重要性;为了识别Hub节点,基于设计结构矩阵和图论的有关知识,对产品开发网络的节点进行聚类;提出了以INI指数作为判定Hub节点"重要性"的量化指标;分析了确定Hub节点个数的方法;在此基础上,阐述了从Hub节点出发的工程变更控制策略。以某型号摩托车发动机为例,验证了所提方法的合理性。