Multi-functional photonic spin Hall effect sensor controlled by phase transition

Photonic spin Hall effect(PSHE), as a novel physical effect in light–matter interaction, provides an effective metrological method for characterizing the tiny variation in refractive index(RI). In this work, we propose a multi-functional PSHE sensor based on VO_(2), a material that can reveal the phase transition behavior. By applying thermal control, the mutual transformation into different phase states of VO_(2) can be realized, which contributes to the flexible switching between multiple RI sensing tasks. When VO_(2) is insulating, the ultrasensitive detection of glucose concentrations in human blood is achieved. When VO_(2) is in a mixed phase, the structure can be designed to distinguish between the normal cells and cancer cells through no-label and real-time monitoring. When VO_(2) is metallic, the proposed PSHE sensor can act as an RI indicator for gas analytes. Compared with other multi-functional sensing devices with the complex structures, our design consists of only one analyte and two VO_(2) layers, which is very simple and elegant. Therefore, the proposed VO_(2)-based PSHE sensor has outstanding advantages such as small size, high sensitivity, no-label, and real-time detection, providing a new approach for investigating tunable multi-functional sensors.

Design of Drilling and Riveting Multi-functional End Effector for CFRP and Aluminum Components in Robotic Aircraft Assembly

To fulfill the demands for higher quality,efficiency and flexibility in aviation industry,a multi-functional end effector is designed to automate the drilling and riveting processes in assembling carbon fiber reinforced polymer(CFRP)and aluminum components for a robotic aircraft assembly system.To meet the specific functional requirements for blind rivet installation on CFRP and aluminum materials,additional modules are incorporated on the end effector aside of the basic processing modules for drilling.And all of these processing modules allow for a onestep-drilling-countersinking process,hole inspection,automatic rivet feed,rivet geometry check,sealant application,rivet insertion and installation.Besides,to guarantee the better quality of the hole drilled and joints riveted,several online detection and adjustment measures are applied to this end effector,including the reference detection and perpendicular calibration,which could effectively ensure the positioning precision and perpendicular accuracy as demanded.Finally,the test result shows that this end effector is capable of producing each hole to a positioning precision within ±0.5 mm,aperpendicular accuracy within 0.3°,a diameter tolerance of H8,and a countersink depth tolerance of±0.01 mm.Moreover,it could drill and rivet up to three joints per minute,with acceptable shearing and tensile strength.

Development of a novel multi-functional integrated bioconjugate effectively targeting K-Ras mutant pancreatic cancer

Folate receptor(FR)overexpression occurs in a variety of cancers,including pancreatic cancer.In addition,enhanced macropinocytosis exists in K-Ras mutant pancreatic cancer.Furthermore,the occurrence of intensive desmoplasia causes a hypoxic microenvironment in pancreatic cancer.In this study,a novel FR-directed,macropinocytosis-enhanced,and highly cytotoxic bioconjugate folate(F)-human serum albumin(HSA)-apoprotein of lidamycin(LDP)-active enediyne(AE)derived from lidamycin was designed and prepared.F-HSA-LDP-AE consisted of four moieties:F,HSA,LDP,and AE.F-HSA-LDP presented high binding efficiency with the FR and pancreatic cancer cells.Its uptake in wild-type cells was more extensive than in K-Ras mutant-type cells.By in vivo optical imaging,F-HSA-LDP displayed prominent tumor-specific biodistribution in pancreatic cancer xenograft-bearing mice,showing clear and lasting tumor localization for 360 h.In the MTT assay,F-HSA-LDP-AE demonstrated potent cytotoxicity in three types of pancreatic cancer cell lines.It also induced apoptosis and caused G2/M cell cycle arrest.F-HSALDP-AE markedly suppressed the tumor growth of AsPc-1 pancreatic cancer xenografts in athymic mice.At well-tolerated doses of 0.5 and 1 mg/kg,(i.v.,twice),the inhibition rates were 91.2%and 94.8%,respectively(P<0.01).The results of this study indicate that the F-HSA-LDP multi-functional bioconjugate might be effective for treating K-Ras mutant pancreatic cancer.

Multi-functional optical fiber sensor system based on a dense wavelength division multiplexer

We propose a novel and efficient multi-functional optical fiber sensor system based on a dense wavelength division multiplexer(DWDM).This system consists of an optical fiber temperature sensor, an optical fiber strain sensor, and a 48-channel DWDM.This system can monitor temperature and strain changes at the same time.The ranges of these two sensors are from-20℃ to 100℃ and from-1000 με to 2000 με, respectively.The sensitivities of the temperature sensor and strain sensor are 0.03572 nm/℃ and 0.03808 nm/N, respectively.With the aid of a broadband source and spectrometer,different kinds and ranges of parameters in the environment can be monitored by using suitable sensors.

A design and application of compound multi-functional sensor in wood-based panel processing

A compound multi-functional sensor was designed by the study on the on-line testing technology of wood-based panels, and its properties of shape, functions, size, resistance to special environment were studied in details. The operational principles of different sensors, technical flow of manufacturing, development of software systems of special functions, and the assessments of technical specification were also be introduced. This sensor adopted many new technologies, such as the applications of piezoresistant effect and heat sensitive effect can effectively measure the pressure and temperature, digital signal processing technology was used to extract and treat signals, and resist interference, encapsulation technology was used to keep the normal run of sensor under a harsh environment. Thus, the on-line compound multi-functional temperature/pressure sensor can be applied better to supervise the production of wood-based panels. All technical specifications of the compound multi-functional sensor were tested and the results met the requirements of the equipments.

Quasi-distribution Appraisal about Finite Element Analysis of Multi-functional Structure Made of Honeycomb Sandwich Materials

A new appraisal method（QDA, quasi-distribution appraisal） which could be used to evaluate the finite element analysis of multi-functional structure made of honeycomb sandwich materials is developed based on sub-section Bezier curve. It is established by simulating the distribution histogram data obtained from the numerical finite element analysis values of a satellite component with sub-section Bezier curve. Being dealt with area normalization method, the simulation curve could be regarded as a kind of probability density function（PDF）, its mathematical expectation and the variance could be used to evaluate the result of finite element analysis. Numerical experiments have indicated that the QDA method demonstrates the intrinsic characteristics of the finite element analysis of multi-functional structure made of honeycomb sandwich materials, as an appraisal method, it is effective and feasible.

Considering calcium-binding proteins in invertebrates: multi-functional proteins that shape neuronal growth

Calcium is a critical second messenger molecule in all cells and is vital in neurons for synaptic transmission.Given this importance,calcium ions are tightly controlled by a host of molecular players including ion channels,sensors,and buffering proteins.Calcium can act directly by binding to signaling molecules or calcium’s effects can be indirect,for example by altering nuclear histones.

Analysis of Dynamic Cross Response between Spindles in a Dual Spindle Type Multi-Functional Turning Machine

In order to meet increasing demand for higher productivity and flexibility, recently many kinds of multi-functional machine tools, which are capable of multiple machining functions or different kinds of machining processes on one machine, have been developed and widely used in manufacturing industries. In this study, a multi-functional turning lathe, which has two spindles and two turrets so that multiple turning operations and various machining processes could be performed simultaneously, has been developed. Furthermore, the equations of correlation between whole responses and cross responses of the two spindles have been derived to examine to what extent the two spindles affect each other’s vibrations.

Design and Development of a Multi-functional Laparoscopic Device

This study presents a design of a multifunctional laparoscopic appendectomy device that includes three surgical instruments commonly used in laparoscopic appendicitis surgeries:endoloop,endobag and scissors.It collects these three independent surgical tools in a single laparoscopic appendectomy device.These days there is a trend of moving to multi-functional surgery devices during minimally invasive surgery.The main reasons behind the minimal invasive surgery are to avoid changing the devices several times during the operation,to reduce the time spent in operation,to increase the efficiency of the operation,to facilitate the follow-up of the camera and devices,and to leave trocars to be used for other surgical instruments.The multi-functional appendectomy device that,we present here,provides these benefits.The standard trocar entries are appropriate for its usage.The presented multifunctional laparoscopic appendectomy device offers more practical use in comparison to individual devices.On the other hand,development of these multi-functional surgery devices can be directly enhanced to the robotic surgery devices.

Design and Development of a Forest Nursery, for the Enhancement of Multi-Functional Agriculture and for a Didactical Purpose

The experimental idea of the present project was elaborated in order to create a structure where different categories and institutions could collaborate, with the common aim to develop a sustainable and profitable agriculture in mountain and marginal areas. The target was the recovering of an abandoned agricultural site, throughout its re-organisation, re-qualification and auto-sustainability, involving local citizens. This approach was based on three further broad functions such as environmental, economic and social purposes. This cooperation, that allows the capitalization of local knowledge and the forging of relationships between local and external sources of expertise, information and advice, is fundamental to the future of existing rural communities, in particular in mountain areas. The model proposed, with the elaboration of a management software and technical agronomic sheets, could be an incentive for the activities already present in that region and to stimulate new ones. The enhancing of the native ecological system, the biodiversity tutelage and the valorization of the knowledge of the territory is the basic requirement for the successful of any land management.

A Portable Multi-functional Real-time Digital Simulator Dedicated to Protective Relay Testing

The paper intfoduces a PC-DSP based real-time digital simulator which is portable in size and aimed at the closed-loop testing of various types of protective relays for their design and application. The simulator can be widely used in not only concerning utilities but also manufacturers and research / certification institutes because of its many functions. The hardware architecture and software implementation of the simulator are described. The main features and functions of the simulator are also

玲珑枕制作技艺信息可视化设计研究

玲珑枕作为我国优秀传统非物质文化遗产之一,历史悠久,具有特有的艺术呈现,其历史文化艺术特色理应传承与保护。文章首先从信息可视化进行阐述,并对玲珑枕概况进行论述,从而提出信息可视化设计与玲珑枕结合的意义,将玲珑枕进行相关信息系统整理归纳和分级,并基于玲珑枕信息可视化设计原则,对玲珑枕制作技艺等相关信息进行可视化设计。利用信息可视化设计对玲珑枕文化进行创新式呈现。为人们提供了更新颖、直接的视觉获取信息体验,扩大玲珑枕信息传播范围,也在一定程度上推动了玲珑枕文化的保护与传承。

Polymer engineering for electrodes of aqueous zinc ion batteries

With the increasing demand for scalable and cost-effective electrochemical energy storage,aqueous zinc ion batteries(AZIBs)have a broad application prospect as an inexpensive,efficient,and naturally secure energy storage device.However,the limitations suffered by AZIBs,including volume expansion and active materials dissolution of the cathode,electrochemical corrosion,irreversible side reactions,zinc dendrites of the anode,have seriously decelerated the civilianization process of AZIBs.Currently,polymers have tremendous superiority for application in AZIBs attributed to their exceptional chemical stability,tunable structure,high energy density and outstanding mechanical properties.Considering the expanding applications of AZIBs and the superiority of polymers,this comprehensive paper meticulously reviews the benefits of utilizing polymeric applied to cathodes and anodes,respectively.To begin with,with adjustable structure as an entry point,the correlation between polymer structure and the function of energy storage as well as optimization is deeply investigated in respect to the mechanism.Then,depending on the diversity of properties and structures,the development of polymers in AZIBs is summarized,including conductive polymers,redox polymers as well as carbon composite polymers for cathode and polyvinylidene fluoride-,carbonyl-,amino-,nitrile-based polymers for anode,and a comprehensive evaluation of the shortcomings of these strategies is provided.Finally,an outlook highlights some of the challenges posed by the application of polymers and offers insights into the potential future direction of polymers in AZIBs.It is designed to provide a thorough reference for researchers and developers working on polymer for AZIBs.

3D打印颈椎枕的压力疼痛评估及信度分析

目的:通过信度分析压痛测量仪评估颈肩部压痛的可靠性,并为3D打印个性化颈椎枕的临床效果评估提供新方式。方法:选取健康受试者36例,分别由2位评估者使用压痛测量仪对其颈肩部肌肉的7个测量点进行2次压痛阈测量,间隔7天后再次测量,采用Spearson相关系数计算评估者内和评估者间的信度,并使用Mann-Whitney U检验比较男性与女性的压痛阈值(pressure pain thresholds,PPT)。个性化颈椎枕使用前后,使用压痛测量仪对13例颈椎病患者选取具有代表性的4个测量点进行PPT测量,用以评估3D打印颈椎枕的治疗效果。结果:除了受测点C5、C6的棘突间旁1cm右侧和肩胛上角左侧外,各受测点评估者内信度均>0.65,各受测点评估者间信度均>0.75,可信度高;C5、C6的棘突间旁1cm右侧和肩胛上角左侧的评估者内组内相关系数(intraclass correlation coefficient,ICC)分别为0.65和0.56,中等信度(P<0.01);健康男性的斜方肌右侧、肩胛上角R、C5、C6的棘突间旁1cm左侧平均值要大于女性(P<0.05);斜方肌右侧、C5、C6的棘突间旁1cm右侧和C5、6的棘突间旁1cm左侧受测点3D打印颈椎枕治疗后的PPT平均值比治疗前大,差异具有显著性意义(P<0.05),说明疼痛有改善。结论:压痛测量仪评估正常健康人颈部压痛阈值信度较高,该方法稳定可靠,可作为3D打印颈椎枕临床效果评估的有效工具。

一种卧床患者靠枕的设计与应用

卧床患者多采用后背垫物体、抬高床头位置等方法来获取半卧位姿势。但现有方法存在执行力不足、角度估计错误、意识不强、遗忘、舒适度下降、易引起压疮和吸入性肺炎等缺点。为了解决现有卧床患者进食体位摆放方法的不足之处,桐乡市中医医院老年医学科团队特设计了一种卧床患者靠枕,用于卧床患者进食时或其他要求半卧位时使用,并获得了国家实用新型专利(专利号:ZL 202122859891.4)。使用时将该装置靠枕放在平坦的床上,靠枕背面紧靠床头用于支撑,防止滑动。患者放于靠置槽内,头部置于第1靠置槽内,肩背部置于第2靠置槽内,腰腹部置于第3靠置槽内,双手放置在靠枕两侧的扶手位置。卧床患者靠枕使用方法简单易学、方便、经济实用、省时省力,而且方便监督检查,能减少误吸、压疮等并发症的发生,进而减轻患方经济负担,改善生活质量,提高患者和家属的满意度,值得在临床推广使用。

运用多维视角融合视觉转换器的食品气调枕形包装漏气检测

食品气调枕形包装被广泛用于农产品的贮藏、运输和消费全流程,尽管工厂广泛使用的现代包装机械和人工检验手段减小了漏气风险,但是封口缺陷、贮藏和运输中的挤压、人工检验时的人为差错等造成漏气甚至瘪袋的情况时有发生,变质的袋内食品既影响了消费者身体健康又导致厂商声誉受损。该文针对食品气调枕形包装的漏气检测问题,提出了一种基于多维视角融合的Vision Transformer漏气检测方法(multi-dimentional fusion vision transformer,MdF-ViT)。通过包装袋的主视角、侧视角和俯视角的融合,提取3个视角包装袋轮廓特征,综合判断包装袋形变量,完成对枕形包装的漏气检测。对样本A、样本B、样本C的测试结果表明,该种模型准确率均达到97.5%,F1值分别达到97.6%、97.6%和97.4%。该研究提出的模型可以有效应用于工厂生产并节约成本。

宋金瓷枕中执莲童子形象卮论

瓷枕作为民俗文化与传统工艺联姻的宁馨儿,其诞生之肇便与用者关系甚切,相较于其他器类,其承载的世俗文化更耐人寻味。宋金时期,瓷枕的烧造达到了鼎盛,执莲童子作为瓷枕中的一种代表性题材,得到了广泛运用。执莲童子与磨喝乐、化生关系甚切,与妇女求子催生有关,表达了祈子宜男的愿景。文章通过阐释执莲童子与磨喝乐、化生的联系,溯回原境,观风察俗,探索宋金瓷枕中执莲童子形象背后的深层意涵。

巨厚膏盐岩形变机制解析及其对油气成藏的影响——以阿姆河右岸东部阿盖雷地区侏罗系为例

阿姆河右岸侏罗系钦莫利阶发育巨厚膏盐岩,其对油气富集成藏具有重要影响。综合利用钻井岩心测试资料和地震资料,通过剖面地质形态分析与地震分频属性刻画,对阿姆河右岸东部阿盖雷地区侏罗系与膏岩层相关的典型构造样式进行了识别,并解析了其形变机制,恢复了关键成藏期的古构造,探讨了不同时期构造运动对油气运聚成藏的控制作用。研究结果表明:①阿盖雷地区侏罗系上盐层上部及上覆地层发育滑脱褶皱,下部发育少量大型盐枕构造,中石膏—下盐层—下石膏层整体变形程度较低,下盐层内发育3种形态小型盐枕构造及盐缩颈,盐枕构造间可识别典型礁/丘滩体。②研究区构造挤压应力和重力滑脱作用是形成膏盐岩形变的主要动力,考虑“2期主要构造运动、先存地貌/构造、多层差异化变形塑性地层、纵横向复合叠加变形”4项关键因素建立了多层叠覆型复杂构造变形模式。③采用基于盐层流动增厚量回填的厚度图法恢复了研究区上盐层沉积前、早白垩世末生烃高峰期的古构造,综合生排烃史、构造发育史、气井产量,明确了基于膏盐岩形变恢复的古构造是天然气富集高产的重要因素,具有“天然气持续充注、多期动态成藏”的演化特征,古、今构造继承性发育区为天然气富集的最有利区。

防压疮异形气囊枕垫及人体外压感知方法研究

为解决规则形气囊枕垫设计算法不足及气囊外表面薄膜压力传感器的透气性和稳定性问题,提出一种防压疮异形气囊枕垫及基于气囊内压-高度模型的人体外压感知方法,通过建立异形气囊的压力-高度-外部载荷模型,测量异形气囊内压力和气囊高度,实现人体外压的推算和稳定感知,以及仰卧或俯卧位的压疮防治。试验结果表明:外压力误差为0.85 N,满足智能防压疮枕垫的压力控制精度。采用人体外压感知方法进行压力感知,避免采用压力薄膜传感器,为重症患者创造更舒适、更安全的护理环境。