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Optimization Design of the Multi-Layer Cross-Sectional Layout of An Umbilical Based on the GA-GLM
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作者 YANG Zhi-xun YIN Xu +5 位作者 FAN Zhi-rui YAN Jun LU Yu-cheng SU Qi MAO Yandong WANG Hua-lin 《China Ocean Engineering》 SCIE EI CSCD 2024年第2期247-254,共8页
Marine umbilical is one of the key equipment for subsea oil and gas exploitation,which is usually integrated by a great number of different functional components with multi-layers.The layout of these components direct... Marine umbilical is one of the key equipment for subsea oil and gas exploitation,which is usually integrated by a great number of different functional components with multi-layers.The layout of these components directly affects manufacturing,operation and storage performances of the umbilical.For the multi-layer cross-sectional layout design of the umbilical,a quantifiable multi-objective optimization model is established according to the operation and storage requirements.Considering the manufacturing factors,the multi-layering strategy based on contact point identification is introduced for a great number of functional components.Then,the GA-GLM global optimization algorithm is proposed combining the genetic algorithm and the generalized multiplier method,and the selection operator of the genetic algorithm is improved based on the steepest descent method.Genetic algorithm is used to find the optimal solution in the global space,which can converge from any initial layout to the feasible layout solution.The feasible layout solution is taken as the initial value of the generalized multiplier method for fast and accurate solution.Finally,taking umbilicals with a great number of components as examples,the results show that the cross-sectional performance of the umbilical obtained by optimization algorithm is better and the solution efficiency is higher.Meanwhile,the multi-layering strategy is effective and feasible.The design method proposed in this paper can quickly obtain the optimal multi-layer cross-sectional layout,which replaces the manual design,and provides useful reference and guidance for the umbilical industry. 展开更多
关键词 UMBILICAL cross-sectional layout multi-layerS GA-GLM optimization
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A flexible ultra-broadband multi-layered absorber working at 2 GHz-40 GHz printed by resistive ink
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作者 汪涛 闫玉伦 +3 位作者 陈巩华 李迎 胡俊 毛剑波 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第2期329-333,共5页
A flexible extra broadband metamaterial absorber(MMA)stacked with five layers working at 2 GHz–40 GHz is investigated.Each layer is composed of polyvinyl chloride(PVC),polyimide(PI),and a frequency selective surface(... A flexible extra broadband metamaterial absorber(MMA)stacked with five layers working at 2 GHz–40 GHz is investigated.Each layer is composed of polyvinyl chloride(PVC),polyimide(PI),and a frequency selective surface(FSS),which is printed on PI using conductive ink.To investigate this absorber,both one-dimensional analogous circuit analysis and three-dimensional full-wave simulation based on a physical model are provided.Various crucial electromagnetic properties,such as absorption,effective impedance,complex permittivity and permeability,electric current distribution and magnetic field distribution at resonant peak points,are studied in detail.Analysis shows that the working frequency of this absorber covers entire S,C,X,Ku,K and Ka bands with a minimum thickness of 0.098λ_(max)(λ_(max) is the maximum wavelength in the absorption band),and the fractional bandwidth(FBW)reaches 181.1%.Moreover,the reflection coefficient is less than-10 dB at 1.998 GHz–40.056 GHz at normal incidence,and the absorptivity of the plane wave is greater than 80%when the incident angle is smaller than 50°.Furthermore,the proposed absorber is experimentally validated,and the experimental results show good agreement with the simulation results,which demonstrates the potential applicability of this absorber at 2 GHz–40 GHz. 展开更多
关键词 extra broadband physical model flexible metamaterial absorber multi-layer frequency selective surface
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Multi-layer perceptron-based data-driven multiscale modelling of granular materials with a novel Frobenius norm-based internal variable
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作者 Mengqi Wang Y.T.Feng +1 位作者 Shaoheng Guan Tongming Qu 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第6期2198-2218,共21页
One objective of developing machine learning(ML)-based material models is to integrate them with well-established numerical methods to solve boundary value problems(BVPs).In the family of ML models,recurrent neural ne... One objective of developing machine learning(ML)-based material models is to integrate them with well-established numerical methods to solve boundary value problems(BVPs).In the family of ML models,recurrent neural networks(RNNs)have been extensively applied to capture history-dependent constitutive responses of granular materials,but these multiple-step-based neural networks are neither sufficiently efficient nor aligned with the standard finite element method(FEM).Single-step-based neural networks like the multi-layer perceptron(MLP)are an alternative to bypass the above issues but have to introduce some internal variables to encode complex loading histories.In this work,one novel Frobenius norm-based internal variable,together with the Fourier layer and residual architectureenhanced MLP model,is crafted to replicate the history-dependent constitutive features of representative volume element(RVE)for granular materials.The obtained ML models are then seamlessly embedded into the FEM to solve the BVP of a biaxial compression case and a rigid strip footing case.The obtained solutions are comparable to results from the FEM-DEM multiscale modelling but achieve significantly improved efficiency.The results demonstrate the applicability of the proposed internal variable in enabling MLP to capture highly nonlinear constitutive responses of granular materials. 展开更多
关键词 Granular materials History-dependence multi-layer perceptron(MLP) Discrete element method FEM-DEM Machine learning
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Target layer state estimation in multi-layer complex dynamical networks considering nonlinear node dynamics
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作者 吴亚勇 王欣伟 蒋国平 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第4期245-252,共8页
In many engineering networks, only a part of target state variables are required to be estimated.On the other hand,multi-layer complex network exists widely in practical situations.In this paper, the state estimation ... In many engineering networks, only a part of target state variables are required to be estimated.On the other hand,multi-layer complex network exists widely in practical situations.In this paper, the state estimation of target state variables in multi-layer complex dynamical networks with nonlinear node dynamics is studied.A suitable functional state observer is constructed with the limited measurement.The parameters of the designed functional observer are obtained from the algebraic method and the stability of the functional observer is proven by the Lyapunov theorem.Some necessary conditions that need to be satisfied for the design of the functional state observer are obtained.Different from previous studies, in the multi-layer complex dynamical network with nonlinear node dynamics, the proposed method can estimate the state of target variables on some layers directly instead of estimating all the individual states.Thus, it can greatly reduce the placement of observers and computational cost.Numerical simulations with the three-layer complex dynamical network composed of three-dimensional nonlinear dynamical nodes are developed to verify the effectiveness of the method. 展开更多
关键词 multi-layer complex dynamical network nonlinear node dynamics target state estimation functional state observer
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Multi-layer phenomena in petawatt laser-driven acceleration of heavy ions
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作者 苏琬晴 曹喜光 +2 位作者 马春旺 王玉廷 张国强 《Plasma Science and Technology》 SCIE EI CAS CSCD 2024年第2期70-76,共7页
Laser-accelerated high-flux-intensity heavy-ion beams are important for new types of accelerators.A particle-in-cell program(Smilei) is employed to simulate the entire process of Station of Extreme Light(SEL) 100 PW l... Laser-accelerated high-flux-intensity heavy-ion beams are important for new types of accelerators.A particle-in-cell program(Smilei) is employed to simulate the entire process of Station of Extreme Light(SEL) 100 PW laser-accelerated heavy particles using different nanoscale short targets with a thickness of 100 nm Cr, Fe, Ag, Ta, Au, Pb, Th and U, as well as 200 nm thick Al and Ca. An obvious stratification is observed in the simulation. The layering phenomenon is a hybrid acceleration mechanism reflecting target normal sheath acceleration and radiation pressure acceleration, and this phenomenon is understood from the simulated energy spectrum,ionization and spatial electric field distribution. According to the stratification, it is suggested that high-quality heavy-ion beams could be expected for fusion reactions to synthesize superheavy nuclei. Two plasma clusters in the stratification are observed simultaneously, which suggest new techniques for plasma experiments as well as thinner metal targets in the precision machining process. 展开更多
关键词 petawatt laser-plasma interaction laser-driven heavy-ion accelerator for synthesizing superheavy nuclei PARTICLE-IN-CELL multi-layer phenomena target fabrication
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Blast wave characteristics of multi-layer composite charge:Theoretical analysis,numerical simulation,and experimental validation 被引量:1
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作者 Jun-bao Li Wei-bing Li +2 位作者 Xiao-wen Hong Jia-xin Yu Jian-jun Zhu 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2023年第1期91-102,共12页
This article investigates the characteristics of shock wave overpressure generated by multi-layer composite charge under different detonation modes.Combining dimensional analysis and the explosion mechanism of the cha... This article investigates the characteristics of shock wave overpressure generated by multi-layer composite charge under different detonation modes.Combining dimensional analysis and the explosion mechanism of the charge,a peak overpressure prediction model for the composite charge under singlepoint detonation and simultaneous detonation was established.The effects of the charge structure and initiation method on the overpressure field characteristics were investigated in AUTODYN simulation.The accuracy of the prediction model and the reliability of the numerical simulation method were subsequently verified in a series of static explosion experiments.The results reveal that the mass of the inner charge was the key factor determining the peak overpressure of the composite charge under single-point detonation.The peak overpressure in the radial direction improved apparently with an increase in the aspect ratio of the charge.The overpressure curves in the axial direction exhibited a multi-peak phenomenon,and the secondary peak overpressure even exceeded the primary peak at distances of 30D and 40D(where D is the charge diameter).The difference in peak overpressure among azimuth angles of 0-90°gradually decreased with an increase in the propagation distance of the shock wave.The coupled effect of the detonation energy of the inner and outer charge under simultaneous detonation improved the overpressure in both radial and axial directions.The difference in peak overpressure obtained from model prediction and experimental measurements was less than 16.4%. 展开更多
关键词 Blast wave characteristics multi-layer composite charge Dimensional analysis AUTODYN mapping Model Explosion experiment
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Optimizing slope safety factor prediction via stacking using sparrow search algorithm for multi-layer machine learning regression models 被引量:1
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作者 SHUI Kuan HOU Ke-peng +2 位作者 HOU Wen-wen SUN Jun-long SUN Hua-fen 《Journal of Mountain Science》 SCIE CSCD 2023年第10期2852-2868,共17页
The safety factor is a crucial quantitative index for evaluating slope stability.However,the traditional calculation methods suffer from unreasonable assumptions,complex soil composition,and inadequate consideration o... The safety factor is a crucial quantitative index for evaluating slope stability.However,the traditional calculation methods suffer from unreasonable assumptions,complex soil composition,and inadequate consideration of the influencing factors,leading to large errors in their calculations.Therefore,a stacking ensemble learning model(stacking-SSAOP)based on multi-layer regression algorithm fusion and optimized by the sparrow search algorithm is proposed for predicting the slope safety factor.In this method,the density,cohesion,friction angle,slope angle,slope height,and pore pressure ratio are selected as characteristic parameters from the 210 sets of established slope sample data.Random Forest,Extra Trees,AdaBoost,Bagging,and Support Vector regression are used as the base model(inner loop)to construct the first-level regression algorithm layer,and XGBoost is used as the meta-model(outer loop)to construct the second-level regression algorithm layer and complete the construction of the stacked learning model for improving the model prediction accuracy.The sparrow search algorithm is used to optimize the hyperparameters of the above six regression models and correct the over-and underfitting problems of the single regression model to further improve the prediction accuracy.The mean square error(MSE)of the predicted and true values and the fitting of the data are compared and analyzed.The MSE of the stacking-SSAOP model was found to be smaller than that of the single regression model(MSE=0.03917).Therefore,the former has a higher prediction accuracy and better data fitting.This study innovatively applies the sparrow search algorithm to predict the slope safety factor,showcasing its advantages over traditional methods.Additionally,our proposed stacking-SSAOP model integrates multiple regression algorithms to enhance prediction accuracy.This model not only refines the prediction accuracy of the slope safety factor but also offers a fresh approach to handling the intricate soil composition and other influencing factors,making it a precise and reliable method for slope stability evaluation.This research holds importance for the modernization and digitalization of slope safety assessments. 展开更多
关键词 multi-layer regression algorithm fusion Stacking gensemblelearning Sparrow search algorithm Slope safety factor Data prediction
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Explosive synchronization of multi-layer complex networks based on star connection between layers with delay
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作者 金彦亮 韩钱源 +2 位作者 郭润珠 高塬 沈礼权 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第10期343-349,共7页
Explosive synchronization(ES)is a kind of first-order jump phenomenon that exists in physical and biological systems.In recent years,researchers have focused on ES between single-layer and multi-layer networks.Most re... Explosive synchronization(ES)is a kind of first-order jump phenomenon that exists in physical and biological systems.In recent years,researchers have focused on ES between single-layer and multi-layer networks.Most research on complex networks with delay has focused on single-layer or double-layer networks,multi-layer networks are seldom explored.In this paper,we propose a Kuramoto model of frequency weights in multi-layer complex networks with delay and star connections between layers.Through theoretical analysis and numerical verification,the factors affecting the backward critical coupling strength are analyzed.The results show that the interaction between layers and the average node degree has a direct effect on the backward critical coupling strength of each layer network.The location of the delay,the size of the delay,the number of network layers,the number of nodes,and the network topology are revealed to have no direct impact on the backward critical coupling strength of the network.Delay is introduced to explore the influence of delay and other related parameters on ES. 展开更多
关键词 multi-layer networks Kuramoto model explosive synchronization DELAY
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AN IMPROVED ELECTRON SCATTERING MODEL IN MULTI-LAYER MEDIUM——“EQUIVALENT SINGLE MEDIUM SCATTERING” CALCULATION METHOD
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作者 何延才 胡幼华 +1 位作者 陈家光 王心磊 《Chinese Science Bulletin》 SCIE EI CAS 1988年第14期1223-1228,共6页
A physical model of ke V electron scattering in multi-layer medium and a Monte Carlo simulation method proposed by the authors have been successfully applied to theoretical calculation on the emission of backscattered... A physical model of ke V electron scattering in multi-layer medium and a Monte Carlo simulation method proposed by the authors have been successfully applied to theoretical calculation on the emission of backscattered electron, X-ray quantitative analysis in multi-layer films and the energy deposition of electron beam exposure.The model is based on the 'equal number of steps and variational step length' con-cept. In the model, when an electron comes from one medium into another, the scattering number of the electron in the 'new' medium is considered as N-n, 展开更多
关键词 multi-layer medium ELECTRON SCATTERING EQUIVALENT SINGLE medium SCATTERING equal step length model
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Detecting Phishing Using a Multi-Layered Social Engineering Framework
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作者 Kofi Sarpong Adu-Manu Richard Kwasi Ahiable 《Journal of Cyber Security》 2023年第1期13-32,共20页
As businesses develop and expand with a significant volume of data,data protection and privacy become increasingly important.Research has shown a tremendous increase in phishing activities during and after COVID-19.Th... As businesses develop and expand with a significant volume of data,data protection and privacy become increasingly important.Research has shown a tremendous increase in phishing activities during and after COVID-19.This research aimed to improve the existing approaches to detecting phishing activities on the internet.We designed a multi-layered phish detection algorithm to detect and prevent phishing applications on the internet using URLs.In the algorithm,we considered technical dimensions of phishing attack prevention and mitigation on the internet.In our approach,we merge,Phishtank,Blacklist,Blocklist,and Whitelist to form our framework.A web application system and browser extension were developed to implement the algorithm.The multi-layer phish detector evaluated ten thousandURLs gathered randomly from the internet(five thousand phishing and five thousand legitimate URLs).The system was estimated to detect levels of accuracy,true-positive and false-positive values.The system level accuracy was recorded to be 98.16%.Approximately 49.6%of the websites were detected as illegitimate,whilst 49.8%were seen as legitimate. 展开更多
关键词 PHISHING social engineering multi-layer framework data protection PRIVACY
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Review on the plastic instability of medium -Mn steels for identifying the formation mechanisms of Lüders and Portevin -Le Chatelier bands
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作者 Bin Hu Han Sui +3 位作者 Qinghua Wen Zheng Wang Alexander Gramlich Haiwen Luo 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第6期1285-1297,共13页
Plastic instability,including both the discontinuous yielding and stress serrations,has been frequently observed during the tensile deformation of medium-Mn steels(MMnS)and has been intensively studied in recent years... Plastic instability,including both the discontinuous yielding and stress serrations,has been frequently observed during the tensile deformation of medium-Mn steels(MMnS)and has been intensively studied in recent years.Unfortunately,research results are controversial,and no consensus has been achieved regarding the topic.Here,we first summarize all the possible factors that affect the yielding and flow stress serrations in MMnS,including the morphology and stability of austenite,the feature of the phase interface,and the deformation parameters.Then,we propose a universal mechanism to explain the conflicting experimental results.We conclude that the discontinuous yielding can be attributed to the lack of mobile dislocation before deformation and the rapid dislocation multiplication at the beginning of plastic deformation.Meanwhile,the results show that the stress serrations are formed due to the pinning and depinning between dislocations and interstitial atoms in austenite.Strain-induced martensitic transformation,influenced by the mechanical stability of austenite grain and deformation parameters,should not be the intrinsic cause of plastic instability.However,it can intensify or weaken the discontinuous yielding and the stress serrations by affecting the mobility and density of dislocations,as well as the interaction between the interstitial atoms and dislocations in austenite grains. 展开更多
关键词 medium manganese steel discontinuous yielding stress serrations retained austenite dislocations
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A Dual-Cluster-Head Based Medium Access Control for Large-Scale UAV Ad-Hoc Networks
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作者 Zhao Xinru Wei Zhiqing +3 位作者 Zou Yingying Ma Hao Cui Yanpeng Feng Zhiyong 《China Communications》 SCIE CSCD 2024年第5期123-136,共14页
Unmanned Aerial Vehicle(UAV)ad hoc network has achieved significant growth for its flexibility,extensibility,and high deployability in recent years.The application of clustering scheme for UAV ad hoc network is impera... Unmanned Aerial Vehicle(UAV)ad hoc network has achieved significant growth for its flexibility,extensibility,and high deployability in recent years.The application of clustering scheme for UAV ad hoc network is imperative to enhance the performance of throughput and energy efficiency.In conventional clustering scheme,a single cluster head(CH)is always assigned in each cluster.However,this method has some weaknesses such as overload and premature death of CH when the number of UAVs increased.In order to solve this problem,we propose a dual-cluster-head based medium access control(DCHMAC)scheme for large-scale UAV networks.In DCHMAC,two CHs are elected to manage resource allocation and data forwarding cooperatively.Specifically,two CHs work on different channels.One of CH is used for intra-cluster communication and the other one is for inter-cluster communication.A Markov chain model is developed to analyse the throughput of the network.Simulation result shows that compared with FM-MAC(flying ad hoc networks multi-channel MAC,FM-MAC),DCHMAC improves the throughput by approximately 20%~50%and prolongs the network lifetime by approximately 40%. 展开更多
关键词 dual cluster head medium access control UAV swarm
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THE INTERIOR TRANSMISSION EIGENVALUE PROBLEM FOR AN ANISOTROPIC MEDIUM BY A PARTIALLY COATED BOUNDARY
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作者 向建立 严国政 《Acta Mathematica Scientia》 SCIE CSCD 2024年第1期339-354,共16页
We consider the interior transmission eigenvalue problem corresponding to the scattering for an anisotropic medium of the scalar Helmholtz equation in the case where the boundary?Ωis split into two disjoint parts and... We consider the interior transmission eigenvalue problem corresponding to the scattering for an anisotropic medium of the scalar Helmholtz equation in the case where the boundary?Ωis split into two disjoint parts and possesses different transmission conditions.Using the variational method,we obtain the well posedness of the interior transmission problem,which plays an important role in the proof of the discreteness of eigenvalues.Then we achieve the existence of an infinite discrete set of transmission eigenvalues provided that n≡1,where a fourth order differential operator is applied.In the case of n■1,we show the discreteness of the transmission eigenvalues under restrictive assumptions by the analytic Fredholm theory and the T-coercive method. 展开更多
关键词 interior transmission eigenvalue anisotropic medium partially coated boundary the analytic Fredholm theory T-coercive method
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Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis
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作者 Tao Liu Ziqian Ma +8 位作者 Liang Liu Yilun Pei Qichao Wu Songjie Xu Yadong Liu Nan Ding Yun Guan Yan Zhang Xueming Chen 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第5期1105-1111,共7页
Human dental pulp stem cell transplantation has been shown to be an effective therapeutic strategy for spinal cord injury.However,whether the human dental pulp stem cell secretome can contribute to functional recovery... Human dental pulp stem cell transplantation has been shown to be an effective therapeutic strategy for spinal cord injury.However,whether the human dental pulp stem cell secretome can contribute to functional recovery after spinal cord injury remains unclear.In the present study,we established a rat model of spinal cord injury based on impact injury from a dropped weight and then intraperitoneally injected the rats with conditioned medium from human dental pulp stem cells.We found that the conditioned medium effectively promoted the recovery of sensory and motor functions in rats with spinal cord injury,decreased expression of the microglial pyroptosis markers NLRP3,GSDMD,caspase-1,and interleukin-1β,promoted axonal and myelin regeneration,and inhibited the formation of glial scars.In addition,in a lipopolysaccharide-induced BV2 microglia model,conditioned medium from human dental pulp stem cells protected cells from pyroptosis by inhibiting the NLRP3/caspase-1/interleukin-1βpathway.These results indicate that conditioned medium from human dental pulp stem cells can reduce microglial pyroptosis by inhibiting the NLRP3/caspase-1/interleukin-1βpathway,thereby promoting the recovery of neurological function after spinal cord injury.Therefore,conditioned medium from human dental pulp stem cells may become an alternative therapy for spinal cord injury. 展开更多
关键词 BV2 conditioned medium dental pulp stem cells GSDMD MICROGLIA NEUROINFLAMMATION NLRP3 PYROPTOSIS spinal cord injury
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Simultaneously realizing thermal andelectromagnetic cloaking by multi-physicalnull medium
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作者 Yichao Liu Xiaomin Ma +6 位作者 Kun Chao Fei Sun Zihao Chen Jinyuan Shan Hanchuan Chen Gang Zhao Shaojie Chen 《Opto-Electronic Science》 2024年第2期45-59,共15页
Simultaneously manipulating multiple physical fields plays an important role in the increasingly complex integrated systems,aerospace equipment,biochemical productions,etc.For on-chip systems with high integration lev... Simultaneously manipulating multiple physical fields plays an important role in the increasingly complex integrated systems,aerospace equipment,biochemical productions,etc.For on-chip systems with high integration level,the precise and efficient control of the propagation of electromagnetic waves and heat fluxes simultaneously is particularly important.In this study,we propose a graphical designing method(i.e.,thermal-electromagnetic surface transformation)based on thermal-electromagnetic null medium to simultaneously control the propagation of electromagnetic waves and thermal fields according to the pre-designed paths.A thermal-electromagnetic cloak,which can create a cloaking effect on both electromagnetic waves and thermal fields simultaneously,is designed by thermal-electromagnetic surface transformation and verified by both numerical simulations and experimental measurements.The thermal-electromagnetic surface transformation proposed in this study provides a new methodology for simultaneous controlling on electromagnetic and temperature fields,and may have significant applications in improving thermal-electromagnetic compatibility problem,protecting of thermal-electromagnetic sensitive components,and improving efficiency of energy usage for complex onchip systems. 展开更多
关键词 transformation optics multi-physical cloak null medium
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Adenosine A_(2A)receptor blockade attenuates excitotoxicity in rat striatal medium spiny neurons during an ischemic-like insult
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作者 Elisabetta Coppi Federica Cherchi Alasdair J.Gibb 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第2期255-257,共3页
During brain ischemia,excitotoxicity and peri-infarct depolarization injuries occur and cause cerebral tissue damage.Indeed,anoxic depolarization,consisting of massive neuronal depolarization due to the loss of membra... During brain ischemia,excitotoxicity and peri-infarct depolarization injuries occur and cause cerebral tissue damage.Indeed,anoxic depolarization,consisting of massive neuronal depolarization due to the loss of membrane ion gradients,occurs in vivo or in vitro during an energy failure.The neuromodulator adenosine is released in huge amounts during cerebral ischemia and exerts its effects by activating specific metabotropic receptors,namely:A_(1),A_(2A),A_(2B),and A_(3).The A_(2A)receptor subtype is highly expressed in striatal medium spiny neurons,which are particularly susceptible to ischemic damage.Evidence indicates that the A2Areceptors are upregulated in the rat striatum after stroke and the selective antagonist SCH58261 protects from exaggerated glutamate release within the first 4 hours from the insult and alleviates neurological impairment and histological injury in the following 24 hours.We recently added new knowledge to the mechanisms by which the adenosine A2Areceptor subtype participates in ischemia-induced neuronal death by performing patch-clamp recordings from medium spiny neurons in rat striatal brain slices exposed to oxygen and glucose deprivation.We demonstrated that the selective block of A2Areceptors by SCH58261 significantly reduced ionic imbalance and delayed the anoxic depolarization in medium spiny neurons during oxygen and glucose deprivation and that the mechanism involves voltage-gated K+channel modulation and a presynaptic inhibition of glutamate release by the A2Areceptor antagonist.The present review summarizes the latest findings in the literature about the possibility of developing selective ligands of A2Areceptors as advantageous therapeutic tools that may contribute to counteracting neurodegeneration after brain ischemia. 展开更多
关键词 adenosine A_(2A)receptors anoxic depolarization brain ischemia glutamate excitotoxicity medium spiny neurons oxygen and glucose deprivation
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Improvement of Temperature Drop Model Parameters for 4200mm/3500mm Rolling of Baosteel Medium and Thick Plate
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作者 Kong Peng 《Frontiers of Metallurgical Industry》 2024年第1期27-30,共4页
Based on the temperature situation during the rolling process of 4200 mm/3500 mm medium and thick plates at Baosteel,this article analyzes the influencing factors of temperature changes during the rolling process from... Based on the temperature situation during the rolling process of 4200 mm/3500 mm medium and thick plates at Baosteel,this article analyzes the influencing factors of temperature changes during the rolling process from the perspective of heat transfer theory and the temperature change law during the rolling process.The temperature loss during the four rolling processes is tracked on site,and the temperature drop model parameters during the rolling process of 4200mm/3500mm medium and thick plates at Baosteel are quantitatively provided.It is applied to actual rolling production and has achieved good results. 展开更多
关键词 medium thickness plate rolling process temperature drop
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In-plane dynamic Green's functions for inclined and uniformly distributed loads in a multi-layered transversely isotropic half-space 被引量:3
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作者 Ba Zhenning Kang Zeqing Liang Jianwen 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2018年第2期293-309,共17页
The dynamic stiffness method combined with the Fourier transform is utilized to derive the in-plane Green’s functions for inclined and uniformly distributed loads in a multi-layered transversely isotropic(TI)half-s... The dynamic stiffness method combined with the Fourier transform is utilized to derive the in-plane Green’s functions for inclined and uniformly distributed loads in a multi-layered transversely isotropic(TI)half-space.The loaded layer is fixed to obtain solutions restricted in it and the corresponding reactions forces,which are then applied to the total system with the opposite sign.By adding solutions restricted in the loaded layer to solutions from the reaction forces,the global solutions in the wavenumber domain are obtained,and the dynamic Green’s functions in the space domain are recovered by the inverse Fourier transform.The presented formulations can be reduced to the isotropic case developed by Wolf(1985),and are further verified by comparisons with existing solutions in a uniform isotropic as well as a layered TI halfspace subjected to horizontally distributed loads which are special cases of the more general problem addressed.The deduced Green’s functions,in conjunction with boundary element methods,will lead to significant advances in the investigation of a variety of wave scattering,wave radiation and soil-structure interaction problems in a layered TI site.Selected numerical results are given to investigate the influence of material anisotropy,frequency of excitation,inclination angle and layered on the responses of displacement and stress,and some conclusions are drawn. 展开更多
关键词 Green's functions transversely isotropic medium multi-layered half-space stiffness method dynamic response
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RECONSTRUCTION OF ONE DIMENSIONAL MULTI-LAYERED MEDIA BY USING A TIME DOMAIN SIGNAL FLOW GRAPH TECHNIQUE 被引量:1
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作者 崔铁军 梁昌洪 《Journal of Electronics(China)》 1993年第2期162-169,共8页
A novel inverse scattering method to reconstruct the permittivity profile of one-dimensional multi-layered media is proposed in this paper.Based on the equivalent network ofthe medium,a concept of time domain signal f... A novel inverse scattering method to reconstruct the permittivity profile of one-dimensional multi-layered media is proposed in this paper.Based on the equivalent network ofthe medium,a concept of time domain signal flow graph and its basic principles are introduced,from which the reflection coefficient of the medium in time domain can be shown to be a series ofDirac δ-functions(pulse responses).In terms of the pulse responses,we will reconstruct both thepermittivity and the thickness of each layer will accurately be reconstructed.Numerical examplesverify the applicability of this 展开更多
关键词 multi-layered medium Reconstruct PERMITTIVITY profile INVERSE SCATTERING Time DOMAIN signal flow GRAPH
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Structural Analysis of the Multi-layer Detachment Folding in Eastern Sichuan Province 被引量:12
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作者 WANG Zongxiu ZHANG Jin +2 位作者 LI Tao XIE Guoai MA Zongjin 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2010年第3期497-514,共18页
A serial of"comb-like and trough-like"folds developed in eastern Sichuan,controlled by the multi-layer detachment folding,is different from the classical Jura-type structure in their development.The key factor resul... A serial of"comb-like and trough-like"folds developed in eastern Sichuan,controlled by the multi-layer detachment folding,is different from the classical Jura-type structure in their development.The key factor resulting in the development of these structures is the occurrence of detachment layers in different parts of Neoprotozoic to Mesozoic stratigraphy of study area,which, from the bottom to the top,are the lower part of Banxi Group,Lower Cambrian(Niutitang Formation),Lower Silurian(Longmaxi Formation and Luoreping Formation),Upper Permian (Wujiaping Formation) and Lower Triassic(Daye Formation).On the basis of field survey combined with sand-box modeling,this study argued that the detachment layer of the lower part of Banxi Group controlled the development of the"comb-like"folds,and the lower part of Cambrian detachment layer controlled the development of"trough-like"folds.Because of several detachment layers occurring in the study area,the development of duplex structures different scales is an important deformation mechanism,and the duplexes are the important structures distinguished from the typical detachment folding structures.Due to these duplexes,the surface structures and structural highs may not be the structural highs in the depth.Meanwhile,the detachment layers are good channels for oil/ gas migration benefiting the understanding of accumulation and migration of oil and gas. 展开更多
关键词 multi-layer detachment folding deformation mechanism thrust tectonics eastern Sichuan
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