This paper describes a new method for three-dimensional medical image registration. In the interactive image-guided HIFU (High Intensity Focused Ultrasound) therapy system, a fast and precise localization of the tumor...This paper describes a new method for three-dimensional medical image registration. In the interactive image-guided HIFU (High Intensity Focused Ultrasound) therapy system, a fast and precise localization of the tumor is very important. An automatic system is developed for registering pre-operative MR images with intra-operative ultrasound images based on the vessels visible in both of the modalities. When the MR and the ultrasound images are aligned, the centerline points of the vessels in the MR image will align with bright intensities in the ultrasound image. The method applies an optimization strategy combining the genetic algorithm with the conjugated gradients algorithm to minimize the objective function. It provides a feasible way of determining the global solution and makes the method robust to local maximum and insensitive to initial position. Two experiments were designed to evaluate the method, and the results show that our method has better registration accuracy and convergence rate than the other two classic algorithms.展开更多
The unsupervised multi-modal image translation is an emerging domain of computer vision whose goal is to transform an image from the source domain into many diverse styles in the target domain.However,the multi-genera...The unsupervised multi-modal image translation is an emerging domain of computer vision whose goal is to transform an image from the source domain into many diverse styles in the target domain.However,the multi-generator mechanism is employed among the advanced approaches available to model different domain mappings,which results in inefficient training of neural networks and pattern collapse,leading to inefficient generation of image diversity.To address this issue,this paper introduces a multi-modal unsupervised image translation framework that uses a generator to perform multi-modal image translation.Specifically,firstly,the domain code is introduced in this paper to explicitly control the different generation tasks.Secondly,this paper brings in the squeeze-and-excitation(SE)mechanism and feature attention(FA)module.Finally,the model integrates multiple optimization objectives to ensure efficient multi-modal translation.This paper performs qualitative and quantitative experiments on multiple non-paired benchmark image translation datasets while demonstrating the benefits of the proposed method over existing technologies.Overall,experimental results have shown that the proposed method is versatile and scalable.展开更多
A new coarse-to-fine strategy was proposed for nonrigid registration of computed tomography(CT) and magnetic resonance(MR) images of a liver.This hierarchical framework consisted of an affine transformation and a B-sp...A new coarse-to-fine strategy was proposed for nonrigid registration of computed tomography(CT) and magnetic resonance(MR) images of a liver.This hierarchical framework consisted of an affine transformation and a B-splines free-form deformation(FFD).The affine transformation performed a rough registration targeting the mismatch between the CT and MR images.The B-splines FFD transformation performed a finer registration by correcting local motion deformation.In the registration algorithm,the normalized mutual information(NMI) was used as similarity measure,and the limited memory Broyden-Fletcher- Goldfarb-Shannon(L-BFGS) optimization method was applied for optimization process.The algorithm was applied to the fully automated registration of liver CT and MR images in three subjects.The results demonstrate that the proposed method not only significantly improves the registration accuracy but also reduces the running time,which is effective and efficient for nonrigid registration.展开更多
BACKGROUND It has been confirmed that three-dimensional(3D)imaging allows easier identification of bile duct anatomy and intraoperative guidance of endoscopic retrograde cholangiopancreatography(ERCP),which reduces th...BACKGROUND It has been confirmed that three-dimensional(3D)imaging allows easier identification of bile duct anatomy and intraoperative guidance of endoscopic retrograde cholangiopancreatography(ERCP),which reduces the radiation dose and procedure time with improved safety.However,current 3D biliary imaging does not have good real-time fusion with intraoperative imaging,a process meant to overcome the influence of intraoperative respiratory motion and guide navigation.The present study explored the feasibility of real-time continuous image-guided ERCP.AIM To explore the feasibility of real-time continuous image-guided ERCP.METHODS We selected 23D-printed abdominal biliary tract models with different structures to simulate different patients.The ERCP environment was simulated for the biliary phantom experiment to create a navigation system,which was further tested in patients.In addition,based on the estimation of the patient’s respiratory motion,preoperative 3D biliary imaging from computed tomography of 18 patients with cholelithiasis was registered and fused in real-time with 2D fluoroscopic sequence generated by the C-arm unit during ERCP.RESULTS Continuous image-guided ERCP was applied in the biliary phantom with a registration error of 0.46 mm±0.13 mm and a tracking error of 0.64 mm±0.24mm.After estimating the respiratory motion,3D/2D registration accurately transformed preoperative 3D biliary images to each image in the X-ray image sequence in real-time in 18 patients,with an average fusion rate of 88%.CONCLUSION Continuous image-guided ERCP may be an effective approach to assist the operator and reduce the use of X-ray and contrast agents.展开更多
Multi‐modal brain image registration has been widely applied to functional localisation,neurosurgery and computational anatomy.The existing registration methods based on the dense deformation fields involve too many ...Multi‐modal brain image registration has been widely applied to functional localisation,neurosurgery and computational anatomy.The existing registration methods based on the dense deformation fields involve too many parameters,which is not conducive to the exploration of correct spatial correspondence between the float and reference images.Meanwhile,the unidirectional registration may involve the deformation folding,which will result in the change of topology during registration.To address these issues,this work has presented an unsupervised image registration method using the free form deformation(FFD)and the symmetry constraint‐based generative adversarial networks(FSGAN).The FSGAN utilises the principle component analysis network‐based structural representations of the reference and float images as the inputs and uses the generator to learn the FFD model parameters,thereby producing two deformation fields.Meanwhile,the FSGAN uses two discriminators to decide whether the bilateral registration have been realised simultaneously.Besides,the symmetry constraint is utilised to construct the loss function,thereby avoiding the deformation folding.Experiments on BrainWeb,high grade gliomas,IXI and LPBA40 show that compared with state‐of‐the‐art methods,the FSGAN provides superior performance in terms of visual comparisons and such quantitative indexes as dice value,target registration error and computational efficiency.展开更多
In order to improve the registration accuracy of brain magnetic resonance images(MRI),some deep learning registration methods use segmentation images for training model.How-ever,the segmentation values are constant fo...In order to improve the registration accuracy of brain magnetic resonance images(MRI),some deep learning registration methods use segmentation images for training model.How-ever,the segmentation values are constant for each label,which leads to the gradient variation con-centrating on the boundary.Thus,the dense deformation field(DDF)is gathered on the boundary and there even appears folding phenomenon.In order to fully leverage the label information,the morphological opening and closing information maps are introduced to enlarge the non-zero gradi-ent regions and improve the accuracy of DDF estimation.The opening information maps supervise the registration model to focus on smaller,narrow brain regions.The closing information maps supervise the registration model to pay more attention to the complex boundary region.Then,opening and closing morphology networks(OC_Net)are designed to automatically generate open-ing and closing information maps to realize the end-to-end training process.Finally,a new registra-tion architecture,VM_(seg+oc),is proposed by combining OC_Net and VoxelMorph.Experimental results show that the registration accuracy of VM_(seg+oc) is significantly improved on LPBA40 and OASIS1 datasets.Especially,VM_(seg+oc) can well improve registration accuracy in smaller brain regions and narrow regions.展开更多
Aiming at the stability of the circuit board image in the acquisition process,this paper realizes the accurate registration of the image to be registered and the standard image based on the SIFT feature operator and R...Aiming at the stability of the circuit board image in the acquisition process,this paper realizes the accurate registration of the image to be registered and the standard image based on the SIFT feature operator and RANSAC algorithm.The device detection model and data set are established based on Faster RCNN.Finally,the number of training was continuously optimized,and when the loss function of Faster RCNN converged,the identification result of the device was obtained.展开更多
Point features, as the basis of lines, surfaces, and bodies, are commonly used in medical image registration. To obtain an elegant spatial transformation of extracted feature points, many point set matching algorithms...Point features, as the basis of lines, surfaces, and bodies, are commonly used in medical image registration. To obtain an elegant spatial transformation of extracted feature points, many point set matching algorithms(PMs) have been developed to match two point sets by optimizing multifarious distance functions. There are ample reviews related to medical image registration and PMs which summarize their basic principles and main algorithms separately. However,to data, detailed summary of PMs used in medical image registration in different clinical environments has not been published. In this paper, we provide a comprehensive review of the existing key techniques of the PMs applied to medical image registration according to the basic principles and clinical applications. As the core technique of the PMs, geometric transformation models are elaborated in this paper, demonstrating the mechanism of point set registration. We also focus on the clinical applications of the PMs and propose a practical classification method according to their applications in different clinical surgeries. The aim of this paper is to provide a summary of pointfeaturebased methods used in medical image registration and to guide doctors or researchers interested in this field to choose appropriate techniques in their research.展开更多
Image fusion aims to integrate complementary information in source images to synthesize a fused image comprehensively characterizing the imaging scene. However, existing image fusion algorithms are only applicable to ...Image fusion aims to integrate complementary information in source images to synthesize a fused image comprehensively characterizing the imaging scene. However, existing image fusion algorithms are only applicable to strictly aligned source images and cause severe artifacts in the fusion results when input images have slight shifts or deformations. In addition,the fusion results typically only have good visual effect, but neglect the semantic requirements of high-level vision tasks.This study incorporates image registration, image fusion, and semantic requirements of high-level vision tasks into a single framework and proposes a novel image registration and fusion method, named Super Fusion. Specifically, we design a registration network to estimate bidirectional deformation fields to rectify geometric distortions of input images under the supervision of both photometric and end-point constraints. The registration and fusion are combined in a symmetric scheme, in which while mutual promotion can be achieved by optimizing the naive fusion loss, it is further enhanced by the mono-modal consistent constraint on symmetric fusion outputs. In addition, the image fusion network is equipped with the global spatial attention mechanism to achieve adaptive feature integration. Moreover, the semantic constraint based on the pre-trained segmentation model and Lovasz-Softmax loss is deployed to guide the fusion network to focus more on the semantic requirements of high-level vision tasks. Extensive experiments on image registration, image fusion,and semantic segmentation tasks demonstrate the superiority of our Super Fusion compared to the state-of-the-art alternatives.The source code and pre-trained model are publicly available at https://github.com/Linfeng-Tang/Super Fusion.展开更多
AIM: To achieve symmetric boundaries for left and right breasts boundaries in thermal images by registration. METHODS: The proposed method for registration consists of two steps. In the first step, shape context, an a...AIM: To achieve symmetric boundaries for left and right breasts boundaries in thermal images by registration. METHODS: The proposed method for registration consists of two steps. In the first step, shape context, an approach as presented by Belongie and Malik was applied for registration of two breast boundaries. The shape context is an approach to measure shape similarity. Two sets of finite sample points from shape contours of two breasts are then presented. Consequently, the correspondences between the two shapes are found. By finding correspondences, the sample point which has the most similar shape context is obtained. RESULTS: In this study, a line up transformation which maps one shape onto the other has been estimated in order to complete shape. The used of a thin plate spline permitted good estimation of a plane transformation which has capability to map unselective points from one shape onto the other. The obtained aligningtransformation of boundaries points has been applied successfully to map the two breasts interior points. Some of advantages for using shape context method in this work are as follows:(1) no special land marks or key points are needed;(2) it is tolerant to all common shape deformation; and(3) although it is uncomplicated and straightforward to use, it gives remarkably powerful descriptor for point sets significantly upgrading point set registration. Results are very promising. The proposed algorithm was implemented for 32 cases. Boundary registration is done perfectly for 28 cases.CONCLUSION: We used shape contexts method that is simple and easy to implement to achieve symmetric boundaries for left and right breasts boundaries in thermal images.展开更多
Fresnel incoherent correlation holography(FINCH) is a unique three-dimensional(3D) imaging technique which has the advantages of scanning-free,high resolution,and easy matching with existing mature optical systems.In ...Fresnel incoherent correlation holography(FINCH) is a unique three-dimensional(3D) imaging technique which has the advantages of scanning-free,high resolution,and easy matching with existing mature optical systems.In this article,an incoherent digital holographic spectral imaging method with high accuracy of spectral reconstruction based on liquid crystal tunable filter(LCTF) and FINCH is proposed.Using the programmable characteristics of spatial light modulator(SLM),a series of phase masks,none of whose focal lengths changes with wavelength,is designed and made.For each wavelength of LCTF output,SLM calls three phase masks with different phase constants at the corresponding wavelength,and CCD records three holograms.The spectral images obtained by this method have a constant magnification,which can achieve pixel-level image registration,restrain image registration errors,and improve spectral reconstruction accuracy.The results show that this method can not only obtain the 3D spatial information and spectral information of the object simultaneously,but also have high accuracy of spectral reconstruction and excellent color reproducibility.展开更多
Interferometric Synthetic Aperture Radar (InSAR) allows production of high resolution DEM and detection of small earth motions using multiple pass SAR data sets obtained by remote sensing satellite. But the whole proc...Interferometric Synthetic Aperture Radar (InSAR) allows production of high resolution DEM and detection of small earth motions using multiple pass SAR data sets obtained by remote sensing satellite. But the whole process has not yet reached sufficient robustness to warrant automated DEM production as commonly produced by stereovision with optical images. The automatic algorithm for precision registration is one of the bottlenecks in InSAR data processing. In this paper, an automatic approach with multi-step image matching algorithm is presented. All procedures are automatically implemented. The experiment is carried out successfully with SIR-C/L-band InSAR data. The triangular piecewise rectification is also advanced in reducing local distortion between the images and processing the large scene image. The primary result has prospect in the precision registration for the repeat-track InSAR data and reveals the potential of the presented automatic strategy.展开更多
AIM: To compare the results of in vivo human high resolution image registration studies of the eye during accommodation to the predictions of mathematical and finite element models of accommodation. METHODS: Data from...AIM: To compare the results of in vivo human high resolution image registration studies of the eye during accommodation to the predictions of mathematical and finite element models of accommodation. METHODS: Data from published high quality image registration studies of pilocarpine induced accommodative changes of equatorial lens radius(ELR) and central lens thickness(CLT) were statistically analyzed. RESULTS: The mean changes in ELR and CLT were 6.76 μm/diopter and 6.51 μm/diopter, respectively. The linear regressions, reflecting the association between ELR and accommodative amplitude(AAELR) was: slope=6.58 μm/diopter, r^2=0.98, P<0.0001 and between CLT and AACLT was: slope=6.75 μm/diopter, r^2=0.83, P<0.001. On the basis of these relationships, the CLT slope and the AAELR were used to predict the measured change in ELR(ELRpredicted). There was no statistical difference between ELRpredicted and the measured ELR as demonstrated by a Student's paired t-test: P=0.96 and linear regression analysis: slope=0.97, r^2=0.98, P<0.00001.CONCLUSION: Image registration with invariant positional references demonstrates that ELR and CLT equivalently minimally increase ~7.0 μm/diopter during accommodation. The small equivalent increases in ELRand CLT are associated with a large accommodative amplitude. These findings are consistent with the predictions of mathematical and finite element models that specified the stiffness of the lens nucleus is the same or greater than the lens cortex and that accommodation involves a small force(<5 g).展开更多
This paper presents a novel medical image registration algorithm named total variation constrained graphregularization for non-negative matrix factorization(TV-GNMF).The method utilizes non-negative matrix factorizati...This paper presents a novel medical image registration algorithm named total variation constrained graphregularization for non-negative matrix factorization(TV-GNMF).The method utilizes non-negative matrix factorization by total variation constraint and graph regularization.The main contributions of our work are the following.First,total variation is incorporated into NMF to control the diffusion speed.The purpose is to denoise in smooth regions and preserve features or details of the data in edge regions by using a diffusion coefficient based on gradient information.Second,we add graph regularization into NMF to reveal intrinsic geometry and structure information of features to enhance the discrimination power.Third,the multiplicative update rules and proof of convergence of the TV-GNMF algorithm are given.Experiments conducted on datasets show that the proposed TV-GNMF method outperforms other state-of-the-art algorithms.展开更多
Three high dimensional spatial standardization algorithms are used for diffusion tensor image(DTI)registration,and seven kinds of methods are used to evaluate their performances.Firstly,the template used in this paper...Three high dimensional spatial standardization algorithms are used for diffusion tensor image(DTI)registration,and seven kinds of methods are used to evaluate their performances.Firstly,the template used in this paper was obtained by spatial transformation of 16 subjects by means of tensor-based standardization.Then,high dimensional standardization algorithms for diffusion tensor images,including fractional anisotropy(FA)based diffeomorphic registration algorithm,FA based elastic registration algorithm and tensor-based registration algorithm,were performed.Finally,7 kinds of evaluation methods,including normalized standard deviation,dyadic coherence,diffusion cross-correlation,overlap of eigenvalue-eigenvector pairs,Euclidean distance of diffusion tensor,and Euclidean distance of the deviatoric tensor and deviatoric of tensors,were used to qualitatively compare and summarize the above standardization algorithms.Experimental results revealed that the high-dimensional tensor-based standardization algorithms perform well and can maintain the consistency of anatomical structures.展开更多
Homologous feature point extraction is a key problem in the optical and synthetic aperture radar (SAR) image registration for islands. A new feature point extraction method using a threshold shrink operator and non-...Homologous feature point extraction is a key problem in the optical and synthetic aperture radar (SAR) image registration for islands. A new feature point extraction method using a threshold shrink operator and non-subsampled wavelet transform (TSO-NSWT) for optical and SAR image registration was proposed. Moreover, the matching for this proposed feature was different from the traditional feature matching strategies and was performed using a similarity measure computed from neighborhood circles in low-frequency bands. Then, a number of reliably matched couples with even distributions were obtained, which assured the accuracy of the registration. Application of the proposed algorithm to SPOT-5 (multi-spectral) and YG-1 (SAR) images showed that a large number of accurately matched couples could be identified. Additionally, both of the root mean square error (RMSE) patterns of the registration parameters computed based on the TSO-NSWT algorithm and traditional NSWT algorithm were analyzed and compared, which further demonstrated the effectiveness of the proposed algorithm. The algorithm can supply the crucial step for island image registration and island recognition.展开更多
The purpose of the study was to evaluate a treatment dose using planning computed tomography (pCT) that was deformed to pre-treatment cone beam computed tomography (CBCT) for lung stereotactic body radiation therapy (...The purpose of the study was to evaluate a treatment dose using planning computed tomography (pCT) that was deformed to pre-treatment cone beam computed tomography (CBCT) for lung stereotactic body radiation therapy (SBRT) treatment. Five lung SBRT patients were retrospectively selected, and their daily CBCTs were employed in this study. Dosimetric comparison was performed between the original and recalculated plans from the deformed pCT (dose per fraction) by comparing a target coverage and organs at risk. Dose summation of five fractions was computed and compared to the original plan. A phantom study was conducted to evaluate the dosimetric accuracy for the dose per fraction. In the phantom study, the difference between the mean Hounsfield Unit (HU) values of the original and deformed pCTs is less than 0.5%. In patient study, the mean HU deviation of the five deformed pCTs compared to that of the original pCT was within ±5%, which is dosimetrically insignificant. While the internal target volume (ITV) shrank by 17% on average among the five patients, mean lung dose (MLD) increased by up to 7%, and D95% of PTV decreased slightly but stayed within 5%. Results showed that MLD might be a better indicative metric of normal lung dose than V20Gy as the ITV volume decreases. This study showed a feasibility to use a deformed pCT for evaluation of the dose per fraction and for a possible plan adaptation in lung SBRT cases. Readers should be cautious in selecting patients before clinical application due to the image quality of CBCT.展开更多
The automatic registration of multi-source remote sensing images (RSI) is a research hotspot of remote sensing image preprocessing currently. A special automatic image registration module named the Image Autosync has ...The automatic registration of multi-source remote sensing images (RSI) is a research hotspot of remote sensing image preprocessing currently. A special automatic image registration module named the Image Autosync has been embedded into the ERDAS IMAGINE software of version 9.0 and above. The registration accuracies of the module verified for the remote sensing images obtained from different platforms or their different spatial resolution. Four tested registration experiments are discussed in this article to analyze the accuracy differences based on the remote sensing data which have different spatial resolution. The impact factors inducing the differences of registration accuracy are also analyzed.展开更多
Image registration is an important issue in medical analysis. In this process the spatial transformation that aligns the reference image and the floating image is estimated by optimizing a similarity metric. Mutual in...Image registration is an important issue in medical analysis. In this process the spatial transformation that aligns the reference image and the floating image is estimated by optimizing a similarity metric. Mutual information (MI), a popular similarity metric, is a reliable criterion for medical image registration. In this paper, we present an improved method for multimodal image registration based on maximization of a new form of normalized MI incorporating particle swarm optimization, PSO, as a searching strategy. Also a new hybrid PSO algorithm is applied to approach more precise and robust results with better performance.展开更多
文摘This paper describes a new method for three-dimensional medical image registration. In the interactive image-guided HIFU (High Intensity Focused Ultrasound) therapy system, a fast and precise localization of the tumor is very important. An automatic system is developed for registering pre-operative MR images with intra-operative ultrasound images based on the vessels visible in both of the modalities. When the MR and the ultrasound images are aligned, the centerline points of the vessels in the MR image will align with bright intensities in the ultrasound image. The method applies an optimization strategy combining the genetic algorithm with the conjugated gradients algorithm to minimize the objective function. It provides a feasible way of determining the global solution and makes the method robust to local maximum and insensitive to initial position. Two experiments were designed to evaluate the method, and the results show that our method has better registration accuracy and convergence rate than the other two classic algorithms.
基金the National Natural Science Foundation of China(No.61976080)the Academic Degrees&Graduate Education Reform Project of Henan Province(No.2021SJGLX195Y)+1 种基金the Teaching Reform Research and Practice Project of Henan Undergraduate Universities(No.2022SYJXLX008)the Key Project on Research and Practice of Henan University Graduate Education and Teaching Reform(No.YJSJG2023XJ006)。
文摘The unsupervised multi-modal image translation is an emerging domain of computer vision whose goal is to transform an image from the source domain into many diverse styles in the target domain.However,the multi-generator mechanism is employed among the advanced approaches available to model different domain mappings,which results in inefficient training of neural networks and pattern collapse,leading to inefficient generation of image diversity.To address this issue,this paper introduces a multi-modal unsupervised image translation framework that uses a generator to perform multi-modal image translation.Specifically,firstly,the domain code is introduced in this paper to explicitly control the different generation tasks.Secondly,this paper brings in the squeeze-and-excitation(SE)mechanism and feature attention(FA)module.Finally,the model integrates multiple optimization objectives to ensure efficient multi-modal translation.This paper performs qualitative and quantitative experiments on multiple non-paired benchmark image translation datasets while demonstrating the benefits of the proposed method over existing technologies.Overall,experimental results have shown that the proposed method is versatile and scalable.
基金Project(61240010)supported by the National Natural Science Foundation of ChinaProject(20070007070)supported by Specialized Research Fund for the Doctoral Program of Higher Education of China
文摘A new coarse-to-fine strategy was proposed for nonrigid registration of computed tomography(CT) and magnetic resonance(MR) images of a liver.This hierarchical framework consisted of an affine transformation and a B-splines free-form deformation(FFD).The affine transformation performed a rough registration targeting the mismatch between the CT and MR images.The B-splines FFD transformation performed a finer registration by correcting local motion deformation.In the registration algorithm,the normalized mutual information(NMI) was used as similarity measure,and the limited memory Broyden-Fletcher- Goldfarb-Shannon(L-BFGS) optimization method was applied for optimization process.The algorithm was applied to the fully automated registration of liver CT and MR images in three subjects.The results demonstrate that the proposed method not only significantly improves the registration accuracy but also reduces the running time,which is effective and efficient for nonrigid registration.
文摘BACKGROUND It has been confirmed that three-dimensional(3D)imaging allows easier identification of bile duct anatomy and intraoperative guidance of endoscopic retrograde cholangiopancreatography(ERCP),which reduces the radiation dose and procedure time with improved safety.However,current 3D biliary imaging does not have good real-time fusion with intraoperative imaging,a process meant to overcome the influence of intraoperative respiratory motion and guide navigation.The present study explored the feasibility of real-time continuous image-guided ERCP.AIM To explore the feasibility of real-time continuous image-guided ERCP.METHODS We selected 23D-printed abdominal biliary tract models with different structures to simulate different patients.The ERCP environment was simulated for the biliary phantom experiment to create a navigation system,which was further tested in patients.In addition,based on the estimation of the patient’s respiratory motion,preoperative 3D biliary imaging from computed tomography of 18 patients with cholelithiasis was registered and fused in real-time with 2D fluoroscopic sequence generated by the C-arm unit during ERCP.RESULTS Continuous image-guided ERCP was applied in the biliary phantom with a registration error of 0.46 mm±0.13 mm and a tracking error of 0.64 mm±0.24mm.After estimating the respiratory motion,3D/2D registration accurately transformed preoperative 3D biliary images to each image in the X-ray image sequence in real-time in 18 patients,with an average fusion rate of 88%.CONCLUSION Continuous image-guided ERCP may be an effective approach to assist the operator and reduce the use of X-ray and contrast agents.
基金supported in part by the National Key Research and Development Program of China under Grant 2018Y FE0206900in part by the National Natural Science Foundation of China under Grant 61871440in part by the CAAIHuawei MindSpore Open Fund.We gratefully acknowledge the support of MindSpore for this research.
文摘Multi‐modal brain image registration has been widely applied to functional localisation,neurosurgery and computational anatomy.The existing registration methods based on the dense deformation fields involve too many parameters,which is not conducive to the exploration of correct spatial correspondence between the float and reference images.Meanwhile,the unidirectional registration may involve the deformation folding,which will result in the change of topology during registration.To address these issues,this work has presented an unsupervised image registration method using the free form deformation(FFD)and the symmetry constraint‐based generative adversarial networks(FSGAN).The FSGAN utilises the principle component analysis network‐based structural representations of the reference and float images as the inputs and uses the generator to learn the FFD model parameters,thereby producing two deformation fields.Meanwhile,the FSGAN uses two discriminators to decide whether the bilateral registration have been realised simultaneously.Besides,the symmetry constraint is utilised to construct the loss function,thereby avoiding the deformation folding.Experiments on BrainWeb,high grade gliomas,IXI and LPBA40 show that compared with state‐of‐the‐art methods,the FSGAN provides superior performance in terms of visual comparisons and such quantitative indexes as dice value,target registration error and computational efficiency.
基金supported by Shandong Provincial Natural Science Foundation(No.ZR2023MF062)the National Natural Science Foundation of China(No.61771230).
文摘In order to improve the registration accuracy of brain magnetic resonance images(MRI),some deep learning registration methods use segmentation images for training model.How-ever,the segmentation values are constant for each label,which leads to the gradient variation con-centrating on the boundary.Thus,the dense deformation field(DDF)is gathered on the boundary and there even appears folding phenomenon.In order to fully leverage the label information,the morphological opening and closing information maps are introduced to enlarge the non-zero gradi-ent regions and improve the accuracy of DDF estimation.The opening information maps supervise the registration model to focus on smaller,narrow brain regions.The closing information maps supervise the registration model to pay more attention to the complex boundary region.Then,opening and closing morphology networks(OC_Net)are designed to automatically generate open-ing and closing information maps to realize the end-to-end training process.Finally,a new registra-tion architecture,VM_(seg+oc),is proposed by combining OC_Net and VoxelMorph.Experimental results show that the registration accuracy of VM_(seg+oc) is significantly improved on LPBA40 and OASIS1 datasets.Especially,VM_(seg+oc) can well improve registration accuracy in smaller brain regions and narrow regions.
文摘Aiming at the stability of the circuit board image in the acquisition process,this paper realizes the accurate registration of the image to be registered and the standard image based on the SIFT feature operator and RANSAC algorithm.The device detection model and data set are established based on Faster RCNN.Finally,the number of training was continuously optimized,and when the loss function of Faster RCNN converged,the identification result of the device was obtained.
基金Supported by the National Natural Science Foundation of China(Grant No.61533016)
文摘Point features, as the basis of lines, surfaces, and bodies, are commonly used in medical image registration. To obtain an elegant spatial transformation of extracted feature points, many point set matching algorithms(PMs) have been developed to match two point sets by optimizing multifarious distance functions. There are ample reviews related to medical image registration and PMs which summarize their basic principles and main algorithms separately. However,to data, detailed summary of PMs used in medical image registration in different clinical environments has not been published. In this paper, we provide a comprehensive review of the existing key techniques of the PMs applied to medical image registration according to the basic principles and clinical applications. As the core technique of the PMs, geometric transformation models are elaborated in this paper, demonstrating the mechanism of point set registration. We also focus on the clinical applications of the PMs and propose a practical classification method according to their applications in different clinical surgeries. The aim of this paper is to provide a summary of pointfeaturebased methods used in medical image registration and to guide doctors or researchers interested in this field to choose appropriate techniques in their research.
基金supported by the National Natural Science Foundation of China(62276192,62075169,62061160370)the Key Research and Development Program of Hubei Province(2020BAB113)。
文摘Image fusion aims to integrate complementary information in source images to synthesize a fused image comprehensively characterizing the imaging scene. However, existing image fusion algorithms are only applicable to strictly aligned source images and cause severe artifacts in the fusion results when input images have slight shifts or deformations. In addition,the fusion results typically only have good visual effect, but neglect the semantic requirements of high-level vision tasks.This study incorporates image registration, image fusion, and semantic requirements of high-level vision tasks into a single framework and proposes a novel image registration and fusion method, named Super Fusion. Specifically, we design a registration network to estimate bidirectional deformation fields to rectify geometric distortions of input images under the supervision of both photometric and end-point constraints. The registration and fusion are combined in a symmetric scheme, in which while mutual promotion can be achieved by optimizing the naive fusion loss, it is further enhanced by the mono-modal consistent constraint on symmetric fusion outputs. In addition, the image fusion network is equipped with the global spatial attention mechanism to achieve adaptive feature integration. Moreover, the semantic constraint based on the pre-trained segmentation model and Lovasz-Softmax loss is deployed to guide the fusion network to focus more on the semantic requirements of high-level vision tasks. Extensive experiments on image registration, image fusion,and semantic segmentation tasks demonstrate the superiority of our Super Fusion compared to the state-of-the-art alternatives.The source code and pre-trained model are publicly available at https://github.com/Linfeng-Tang/Super Fusion.
文摘AIM: To achieve symmetric boundaries for left and right breasts boundaries in thermal images by registration. METHODS: The proposed method for registration consists of two steps. In the first step, shape context, an approach as presented by Belongie and Malik was applied for registration of two breast boundaries. The shape context is an approach to measure shape similarity. Two sets of finite sample points from shape contours of two breasts are then presented. Consequently, the correspondences between the two shapes are found. By finding correspondences, the sample point which has the most similar shape context is obtained. RESULTS: In this study, a line up transformation which maps one shape onto the other has been estimated in order to complete shape. The used of a thin plate spline permitted good estimation of a plane transformation which has capability to map unselective points from one shape onto the other. The obtained aligningtransformation of boundaries points has been applied successfully to map the two breasts interior points. Some of advantages for using shape context method in this work are as follows:(1) no special land marks or key points are needed;(2) it is tolerant to all common shape deformation; and(3) although it is uncomplicated and straightforward to use, it gives remarkably powerful descriptor for point sets significantly upgrading point set registration. Results are very promising. The proposed algorithm was implemented for 32 cases. Boundary registration is done perfectly for 28 cases.CONCLUSION: We used shape contexts method that is simple and easy to implement to achieve symmetric boundaries for left and right breasts boundaries in thermal images.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.61505178,61307019,and 11504333)the Natural Science Foundation of Henan Province,China(Grant Nos.18A140032,15A140038,and 16A140035)。
文摘Fresnel incoherent correlation holography(FINCH) is a unique three-dimensional(3D) imaging technique which has the advantages of scanning-free,high resolution,and easy matching with existing mature optical systems.In this article,an incoherent digital holographic spectral imaging method with high accuracy of spectral reconstruction based on liquid crystal tunable filter(LCTF) and FINCH is proposed.Using the programmable characteristics of spatial light modulator(SLM),a series of phase masks,none of whose focal lengths changes with wavelength,is designed and made.For each wavelength of LCTF output,SLM calls three phase masks with different phase constants at the corresponding wavelength,and CCD records three holograms.The spectral images obtained by this method have a constant magnification,which can achieve pixel-level image registration,restrain image registration errors,and improve spectral reconstruction accuracy.The results show that this method can not only obtain the 3D spatial information and spectral information of the object simultaneously,but also have high accuracy of spectral reconstruction and excellent color reproducibility.
基金Project supported by the National Natural Science Foundation of China(No.69782001)
文摘Interferometric Synthetic Aperture Radar (InSAR) allows production of high resolution DEM and detection of small earth motions using multiple pass SAR data sets obtained by remote sensing satellite. But the whole process has not yet reached sufficient robustness to warrant automated DEM production as commonly produced by stereovision with optical images. The automatic algorithm for precision registration is one of the bottlenecks in InSAR data processing. In this paper, an automatic approach with multi-step image matching algorithm is presented. All procedures are automatically implemented. The experiment is carried out successfully with SIR-C/L-band InSAR data. The triangular piecewise rectification is also advanced in reducing local distortion between the images and processing the large scene image. The primary result has prospect in the precision registration for the repeat-track InSAR data and reveals the potential of the presented automatic strategy.
文摘AIM: To compare the results of in vivo human high resolution image registration studies of the eye during accommodation to the predictions of mathematical and finite element models of accommodation. METHODS: Data from published high quality image registration studies of pilocarpine induced accommodative changes of equatorial lens radius(ELR) and central lens thickness(CLT) were statistically analyzed. RESULTS: The mean changes in ELR and CLT were 6.76 μm/diopter and 6.51 μm/diopter, respectively. The linear regressions, reflecting the association between ELR and accommodative amplitude(AAELR) was: slope=6.58 μm/diopter, r^2=0.98, P<0.0001 and between CLT and AACLT was: slope=6.75 μm/diopter, r^2=0.83, P<0.001. On the basis of these relationships, the CLT slope and the AAELR were used to predict the measured change in ELR(ELRpredicted). There was no statistical difference between ELRpredicted and the measured ELR as demonstrated by a Student's paired t-test: P=0.96 and linear regression analysis: slope=0.97, r^2=0.98, P<0.00001.CONCLUSION: Image registration with invariant positional references demonstrates that ELR and CLT equivalently minimally increase ~7.0 μm/diopter during accommodation. The small equivalent increases in ELRand CLT are associated with a large accommodative amplitude. These findings are consistent with the predictions of mathematical and finite element models that specified the stiffness of the lens nucleus is the same or greater than the lens cortex and that accommodation involves a small force(<5 g).
基金supported by the National Natural Science Foundation of China(61702251,41971424,61701191,U1605254)the Natural Science Basic Research Plan in Shaanxi Province of China(2018JM6030)+4 种基金the Key Technical Project of Fujian Province(2017H6015)the Science and Technology Project of Xiamen(3502Z20183032)the Doctor Scientific Research Starting Foundation of Northwest University(338050050)Youth Academic Talent Support Program of Northwest University(360051900151)the Natural Sciences and Engineering Research Council of Canada,Canada。
文摘This paper presents a novel medical image registration algorithm named total variation constrained graphregularization for non-negative matrix factorization(TV-GNMF).The method utilizes non-negative matrix factorization by total variation constraint and graph regularization.The main contributions of our work are the following.First,total variation is incorporated into NMF to control the diffusion speed.The purpose is to denoise in smooth regions and preserve features or details of the data in edge regions by using a diffusion coefficient based on gradient information.Second,we add graph regularization into NMF to reveal intrinsic geometry and structure information of features to enhance the discrimination power.Third,the multiplicative update rules and proof of convergence of the TV-GNMF algorithm are given.Experiments conducted on datasets show that the proposed TV-GNMF method outperforms other state-of-the-art algorithms.
基金Supported by the National Key Research and Development Program of China(2016YFC0100300)the National Natural Science Foundation of China(61402371,61771369)+1 种基金the Natural Science Basic Research Plan in Shaanxi Province of China(2017JM6008)the Fundamental Research Funds for the Central Universities of China(3102017zy032,3102018zy020)
文摘Three high dimensional spatial standardization algorithms are used for diffusion tensor image(DTI)registration,and seven kinds of methods are used to evaluate their performances.Firstly,the template used in this paper was obtained by spatial transformation of 16 subjects by means of tensor-based standardization.Then,high dimensional standardization algorithms for diffusion tensor images,including fractional anisotropy(FA)based diffeomorphic registration algorithm,FA based elastic registration algorithm and tensor-based registration algorithm,were performed.Finally,7 kinds of evaluation methods,including normalized standard deviation,dyadic coherence,diffusion cross-correlation,overlap of eigenvalue-eigenvector pairs,Euclidean distance of diffusion tensor,and Euclidean distance of the deviatoric tensor and deviatoric of tensors,were used to qualitatively compare and summarize the above standardization algorithms.Experimental results revealed that the high-dimensional tensor-based standardization algorithms perform well and can maintain the consistency of anatomical structures.
基金The National Natural Science Foundation of China under contract No.41271409the National Key Technology Research and Development Program under contract No.2011BAH23B00the National High Technology Research and Development Program(863 Program)of China under contract No.2012AA12A406
文摘Homologous feature point extraction is a key problem in the optical and synthetic aperture radar (SAR) image registration for islands. A new feature point extraction method using a threshold shrink operator and non-subsampled wavelet transform (TSO-NSWT) for optical and SAR image registration was proposed. Moreover, the matching for this proposed feature was different from the traditional feature matching strategies and was performed using a similarity measure computed from neighborhood circles in low-frequency bands. Then, a number of reliably matched couples with even distributions were obtained, which assured the accuracy of the registration. Application of the proposed algorithm to SPOT-5 (multi-spectral) and YG-1 (SAR) images showed that a large number of accurately matched couples could be identified. Additionally, both of the root mean square error (RMSE) patterns of the registration parameters computed based on the TSO-NSWT algorithm and traditional NSWT algorithm were analyzed and compared, which further demonstrated the effectiveness of the proposed algorithm. The algorithm can supply the crucial step for island image registration and island recognition.
文摘The purpose of the study was to evaluate a treatment dose using planning computed tomography (pCT) that was deformed to pre-treatment cone beam computed tomography (CBCT) for lung stereotactic body radiation therapy (SBRT) treatment. Five lung SBRT patients were retrospectively selected, and their daily CBCTs were employed in this study. Dosimetric comparison was performed between the original and recalculated plans from the deformed pCT (dose per fraction) by comparing a target coverage and organs at risk. Dose summation of five fractions was computed and compared to the original plan. A phantom study was conducted to evaluate the dosimetric accuracy for the dose per fraction. In the phantom study, the difference between the mean Hounsfield Unit (HU) values of the original and deformed pCTs is less than 0.5%. In patient study, the mean HU deviation of the five deformed pCTs compared to that of the original pCT was within ±5%, which is dosimetrically insignificant. While the internal target volume (ITV) shrank by 17% on average among the five patients, mean lung dose (MLD) increased by up to 7%, and D95% of PTV decreased slightly but stayed within 5%. Results showed that MLD might be a better indicative metric of normal lung dose than V20Gy as the ITV volume decreases. This study showed a feasibility to use a deformed pCT for evaluation of the dose per fraction and for a possible plan adaptation in lung SBRT cases. Readers should be cautious in selecting patients before clinical application due to the image quality of CBCT.
文摘The automatic registration of multi-source remote sensing images (RSI) is a research hotspot of remote sensing image preprocessing currently. A special automatic image registration module named the Image Autosync has been embedded into the ERDAS IMAGINE software of version 9.0 and above. The registration accuracies of the module verified for the remote sensing images obtained from different platforms or their different spatial resolution. Four tested registration experiments are discussed in this article to analyze the accuracy differences based on the remote sensing data which have different spatial resolution. The impact factors inducing the differences of registration accuracy are also analyzed.
文摘Image registration is an important issue in medical analysis. In this process the spatial transformation that aligns the reference image and the floating image is estimated by optimizing a similarity metric. Mutual information (MI), a popular similarity metric, is a reliable criterion for medical image registration. In this paper, we present an improved method for multimodal image registration based on maximization of a new form of normalized MI incorporating particle swarm optimization, PSO, as a searching strategy. Also a new hybrid PSO algorithm is applied to approach more precise and robust results with better performance.