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Ecological network analysis reveals complex responses of tree species life stage interactions to stand variables
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作者 Hengchao Zou Huayong Zhang Tousheng Huang 《Journal of Forestry Research》 SCIE EI CAS CSCD 2024年第1期29-43,共15页
Tree interactions are essential for the structure,dynamics,and function of forest ecosystems,but variations in the architecture of life-stage interaction networks(LSINs)across forests is unclear.Here,we constructed 16... Tree interactions are essential for the structure,dynamics,and function of forest ecosystems,but variations in the architecture of life-stage interaction networks(LSINs)across forests is unclear.Here,we constructed 16 LSINs in the mountainous forests of northwest Hebei,China based on crown overlap from four mixed forests with two dominant tree species.Our results show that LSINs decrease the complexity of stand densities and basal areas due to the interaction cluster differentiation.In addition,we found that mature trees and saplings play different roles,the first acting as“hub”life stages with high connectivity and the second,as“bridges”controlling information flow with high centrality.Across the forests,life stages with higher importance showed better parameter stability within LSINs.These results reveal that the structure of tree interactions among life stages is highly related to stand variables.Our efforts contribute to the understanding of LSIN complexity and provide a basis for further research on tree interactions in complex forest communities. 展开更多
关键词 Tree interactions Life stages interaction networks Ecological complexity
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Impact of different interaction behavior on epidemic spreading in time-dependent social networks
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作者 黄帅 陈杰 +2 位作者 李梦玉 徐元昊 胡茂彬 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第3期190-195,共6页
We investigate the impact of pairwise and group interactions on the spread of epidemics through an activity-driven model based on time-dependent networks.The effects of pairwise/group interaction proportion and pairwi... We investigate the impact of pairwise and group interactions on the spread of epidemics through an activity-driven model based on time-dependent networks.The effects of pairwise/group interaction proportion and pairwise/group interaction intensity are explored by extensive simulation and theoretical analysis.It is demonstrated that altering the group interaction proportion can either hinder or enhance the spread of epidemics,depending on the relative social intensity of group and pairwise interactions.As the group interaction proportion decreases,the impact of reducing group social intensity diminishes.The ratio of group and pairwise social intensity can affect the effect of group interaction proportion on the scale of infection.A weak heterogeneous activity distribution can raise the epidemic threshold,and reduce the scale of infection.These results benefit the design of epidemic control strategy. 展开更多
关键词 epidemic transmission complex network time-dependent networks social interaction
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Opinion consensus incorporating higher-order interactions in individual-collective networks
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作者 叶顺 涂俐兰 +2 位作者 王先甲 胡佳 王薏潮 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第7期105-115,共11页
In the current information society, the dissemination mechanisms and evolution laws of individual or collective opinions and their behaviors are the research hot topics in the field of opinion dynamics. First, in this... In the current information society, the dissemination mechanisms and evolution laws of individual or collective opinions and their behaviors are the research hot topics in the field of opinion dynamics. First, in this paper, a two-layer network consisting of an individual-opinion layer and a collective-opinion layer is constructed, and a dissemination model of opinions incorporating higher-order interactions(i.e. OIHOI dissemination model) is proposed. Furthermore, the dynamic equations of opinion dissemination for both individuals and groups are presented. Using Lyapunov's first method,two equilibrium points, including the negative consensus point and positive consensus point, and the dynamic equations obtained for opinion dissemination, are analyzed theoretically. In addition, for individual opinions and collective opinions,some conditions for reaching negative consensus and positive consensus as well as the theoretical expression for the dissemination threshold are put forward. Numerical simulations are carried to verify the feasibility and effectiveness of the proposed theoretical results, as well as the influence of the intra-structure, inter-connections, and higher-order interactions on the dissemination and evolution of individual opinions. The main results are as follows.(i) When the intra-structure of the collective-opinion layer meets certain characteristics, then a negative or positive consensus is easier to reach for individuals.(ii) Both negative consensus and positive consensus perform best in mixed type of inter-connections in the two-layer network.(iii) Higher-order interactions can quickly eliminate differences in individual opinions, thereby enabling individuals to reach consensus faster. 展开更多
关键词 two-layer social networks individual and collective opinions higher-order interactions CONSENSUS Lyapunov's first method
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Disease networks. Uncovering disease-disease relationships through the incomplete interactome
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作者 Jorg Menche 《四川生理科学杂志》 2024年第1期199-199,共1页
According to the disease module hypothesis,the cellular components associated with a disease segregate in the same neighborhood of the human interactome,the map of biologically relevant molecular interactions.Yet,give... According to the disease module hypothesis,the cellular components associated with a disease segregate in the same neighborhood of the human interactome,the map of biologically relevant molecular interactions.Yet,given the incompleteness of the interactome and the limited knowledge of disease-associated genes,it is not obvious if the available data have sufficient coverage to map out modules associated with each disease. 展开更多
关键词 INCOMPLETE interactions. networks.
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LncRNAs exert indispensable roles in orchestrating the interaction among diverse noncoding RNAs and enrich the regulatory network of plant growth and its adaptive environmental stress response
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作者 Lingling Zhang Tao Lin +3 位作者 Guoning Zhu Bin Wu Chunjiao Zhang Hongliang Zhu 《Horticulture Research》 SCIE CSCD 2023年第12期304-315,共12页
With the advent of advanced sequencing technologies,non-coding RNAs(ncRNAs)are increasingly pivotal and play highly regulated roles in the modulation of diverse aspects of plant growth and stress response.This include... With the advent of advanced sequencing technologies,non-coding RNAs(ncRNAs)are increasingly pivotal and play highly regulated roles in the modulation of diverse aspects of plant growth and stress response.This includes a spectrum of ncRNA classes,ranging from small RNAs to long non-coding RNAs(lncRNAs).Notably,among these,lncRNAs emerge as significant and intricate components within the broader ncRNA regulatory networks.Here,we categorize ncRNAs based on their length and structure into small RNAs,medium-sized ncRNAs,lncRNAs,and circle RNAs.Furthermore,the review delves into the detailed biosynthesis and origin of these ncRNAs.Subsequently,we emphasize the diverse regulatory mechanisms employed by lncRNAs that are located at various gene regions of coding genes,embodying promoters,5’UTRs,introns,exons,and 3’UTR regions.Furthermore,we elucidate these regulatory modes through one or two concrete examples.Besides,lncRNAs have emerged as novel central components that participate in phase separation processes.Moreover,we illustrate the coordinated regulatory mechanisms among lncRNAs,miRNAs,and siRNAs with a particular emphasis on the central role of lncRNAs in serving as sponges,precursors,spliceosome,stabilization,scaffolds,or interaction factors to bridge interactions with other ncRNAs.The review also sheds light on the intriguing possibility that some ncRNAs may encode functional micropeptides.Therefore,the review underscores the emergent roles of ncRNAs as potent regulatory factors that significantly enrich the regulatory network governing plant growth,development,and responses to environmental stimuli.There are yet-to-be-discovered roles of ncRNAs waiting for us to explore. 展开更多
关键词 interactION STRESS network
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Information perception and feedback mechanism and key techniques of multi-modality human-robot interaction for service robots 被引量:1
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作者 赵其杰 《Journal of Shanghai University(English Edition)》 CAS 2006年第3期281-281,共1页
With the increasing of the elderly population and the growing hearth care cost, the role of service robots in aiding the disabled and the elderly is becoming important. Many researchers in the world have paid much att... With the increasing of the elderly population and the growing hearth care cost, the role of service robots in aiding the disabled and the elderly is becoming important. Many researchers in the world have paid much attention to heaRthcare robots and rehabilitation robots. To get natural and harmonious communication between the user and a service robot, the information perception/feedback ability, and interaction ability for service robots become more important in many key issues. 展开更多
关键词 service robot multi-modality human-robot interaction user model interaction protocol information perception and feedback.
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Lateral interaction by Laplacian‐based graph smoothing for deep neural networks
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作者 Jianhui Chen Zuoren Wang Cheng‐Lin Liu 《CAAI Transactions on Intelligence Technology》 SCIE EI 2023年第4期1590-1607,共18页
Lateral interaction in the biological brain is a key mechanism that underlies higher cognitive functions.Linear self‐organising map(SOM)introduces lateral interaction in a general form in which signals of any modalit... Lateral interaction in the biological brain is a key mechanism that underlies higher cognitive functions.Linear self‐organising map(SOM)introduces lateral interaction in a general form in which signals of any modality can be used.Some approaches directly incorporate SOM learning rules into neural networks,but incur complex operations and poor extendibility.The efficient way to implement lateral interaction in deep neural networks is not well established.The use of Laplacian Matrix‐based Smoothing(LS)regularisation is proposed for implementing lateral interaction in a concise form.The authors’derivation and experiments show that lateral interaction implemented by SOM model is a special case of LS‐regulated k‐means,and they both show the topology‐preserving capability.The authors also verify that LS‐regularisation can be used in conjunction with the end‐to‐end training paradigm in deep auto‐encoders.Additionally,the benefits of LS‐regularisation in relaxing the requirement of parameter initialisation in various models and improving the classification performance of prototype classifiers are evaluated.Furthermore,the topologically ordered structure introduced by LS‐regularisation in feature extractor can improve the generalisation performance on classification tasks.Overall,LS‐regularisation is an effective and efficient way to implement lateral interaction and can be easily extended to different models. 展开更多
关键词 artificial neural networks biologically plausible Laplacian‐based graph smoothing lateral interaction machine learning
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Drug–Target Interaction Prediction Model Using Optimal Recurrent Neural Network
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作者 G.Kavipriya D.Manjula 《Intelligent Automation & Soft Computing》 SCIE 2023年第2期1675-1689,共15页
Drug-target interactions prediction(DTIP)remains an important requirement in thefield of drug discovery and human medicine.The identification of interaction among the drug compound and target protein plays an essential ... Drug-target interactions prediction(DTIP)remains an important requirement in thefield of drug discovery and human medicine.The identification of interaction among the drug compound and target protein plays an essential pro-cess in the drug discovery process.It is a lengthier and complex process for pre-dicting the drug target interaction(DTI)utilizing experimental approaches.To resolve these issues,computational intelligence based DTIP techniques were developed to offer an efficient predictive model with low cost.The recently devel-oped deep learning(DL)models can be employed for the design of effective pre-dictive approaches for DTIP.With this motivation,this paper presents a new drug target interaction prediction using optimal recurrent neural network(DTIP-ORNN)technique.The goal of the DTIP-ORNN technique is to predict the DTIs in a semi-supervised way,i.e.,inclusion of both labelled and unlabelled instances.Initially,the DTIP-ORNN technique performs data preparation process and also includes class labelling process,where the target interactions from the database are used to determine thefinal label of the unlabelled instances.Besides,drug-to-drug(D-D)and target-to-target(T-T)interactions are used for the weight initia-tion of the RNN based bidirectional long short term memory(BiLSTM)model which is then utilized to the prediction of DTIs.Since hyperparameters signifi-cantly affect the prediction performance of the BiLSTM technique,the Adam optimizer is used which mainly helps to improve the DTI prediction outcomes.In order to ensure the enhanced predictive outcomes of the DTIP-ORNN techni-que,a series of simulations are implemented on four benchmark datasets.The comparative result analysis shows the promising performance of the DTIP-ORNN method on the recent approaches. 展开更多
关键词 Drug target interaction deep learning recurrent neural network parameter tuning semi-supervised learning
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Construction of gene/protein interaction networks and enrichment pathway analysis for paroxysmal nocturnal hemoglobinuria and aplastic anemia
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作者 Gong-Xi Liu Zheng-Di Sun +2 位作者 Chao Zhou Jun-Yu Wei Jing Zhuang 《Medical Theory and Hypothesis》 2023年第2期19-26,共8页
Background:To develop a protein-protein interaction network of Paroxysmal nocturnal hemoglobinuria(PNH)and Aplastic anemia(AA)based on genetic genes and to predict pathways underlying the molecular complexes in the ne... Background:To develop a protein-protein interaction network of Paroxysmal nocturnal hemoglobinuria(PNH)and Aplastic anemia(AA)based on genetic genes and to predict pathways underlying the molecular complexes in the network.Methods:In this research,the PNH and AA-related genes were screened through Online Mendelian Inheritance in Man(OMIM).The plugins and Cytoscape were used to search literature and build a protein-protein interaction network.Results:The protein-protein interaction network contains two molecular complexes that are five higher than the correlation integral values.The target genes of this study were obtained:CD59,STAT3,TERC,TNF,AKT1,C5AR1,EPO,IL6,IL10 and so on.We also found that many factors regulate biological behaviors:neutrophils,macrophages,vascular endothelial growth factor,immunoglobulin,interleukin,cytokine receptor,interleukin-6 receptor,tumor necrosis factor,and so on.This research provides a bioinformatics foundation for further explaining the mechanism of common development of both.Conclusion:This indicates that the PNH and AA is a complex process regulated by many cellular pathways and multiple genes. 展开更多
关键词 protein interaction networks paroxysmal nocturnal hemoglobinuria Online Mendelian Inheritance in Man database aplastic anemia biological pathways
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Research on Multi-modal In-Vehicle Intelligent Personal Assistant Design
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作者 WANG Jia-rou TANG Cheng-xin SHUAI Liang-ying 《印刷与数字媒体技术研究》 CAS 北大核心 2024年第4期136-146,共11页
Intelligent personal assistants play a pivotal role in in-vehicle systems,significantly enhancing life efficiency,driving safety,and decision-making support.In this study,the multi-modal design elements of intelligent... Intelligent personal assistants play a pivotal role in in-vehicle systems,significantly enhancing life efficiency,driving safety,and decision-making support.In this study,the multi-modal design elements of intelligent personal assistants within the context of visual,auditory,and somatosensory interactions with drivers were discussed.Their impact on the driver’s psychological state through various modes such as visual imagery,voice interaction,and gesture interaction were explored.The study also introduced innovative designs for in-vehicle intelligent personal assistants,incorporating design principles such as driver-centricity,prioritizing passenger safety,and utilizing timely feedback as a criterion.Additionally,the study employed design methods like driver behavior research and driving situation analysis to enhance the emotional connection between drivers and their vehicles,ultimately improving driver satisfaction and trust. 展开更多
关键词 Intelligent personal assistants multi-modal design User psychology In-vehicle interaction Voice interaction Emotional design
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Fake News Detection Based on Cross-Modal Message Aggregation and Gated Fusion Network
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作者 Fangfang Shan Mengyao Liu +1 位作者 Menghan Zhang Zhenyu Wang 《Computers, Materials & Continua》 SCIE EI 2024年第7期1521-1542,共22页
Social media has become increasingly significant in modern society,but it has also turned into a breeding ground for the propagation of misleading information,potentially causing a detrimental impact on public opinion... Social media has become increasingly significant in modern society,but it has also turned into a breeding ground for the propagation of misleading information,potentially causing a detrimental impact on public opinion and daily life.Compared to pure text content,multmodal content significantly increases the visibility and share ability of posts.This has made the search for efficient modality representations and cross-modal information interaction methods a key focus in the field of multimodal fake news detection.To effectively address the critical challenge of accurately detecting fake news on social media,this paper proposes a fake news detection model based on crossmodal message aggregation and a gated fusion network(MAGF).MAGF first uses BERT to extract cumulative textual feature representations and word-level features,applies Faster Region-based ConvolutionalNeuralNetwork(Faster R-CNN)to obtain image objects,and leverages ResNet-50 and Visual Geometry Group-19(VGG-19)to obtain image region features and global features.The image region features and word-level text features are then projected into a low-dimensional space to calculate a text-image affinity matrix for cross-modal message aggregation.The gated fusion network combines text and image region features to obtain adaptively aggregated features.The interaction matrix is derived through an attention mechanism and further integrated with global image features using a co-attention mechanism to producemultimodal representations.Finally,these fused features are fed into a classifier for news categorization.Experiments were conducted on two public datasets,Twitter and Weibo.Results show that the proposed model achieves accuracy rates of 91.8%and 88.7%on the two datasets,respectively,significantly outperforming traditional unimodal and existing multimodal models. 展开更多
关键词 Fake news detection cross-modalmessage aggregation gate fusion network co-attention mechanism multi-modal representation
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Fake News Detection Based on Text-Modal Dominance and Fusing Multiple Multi-Model Clues
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作者 Li fang Fu Huanxin Peng +1 位作者 Changjin Ma Yuhan Liu 《Computers, Materials & Continua》 SCIE EI 2024年第3期4399-4416,共18页
In recent years,how to efficiently and accurately identify multi-model fake news has become more challenging.First,multi-model data provides more evidence but not all are equally important.Secondly,social structure in... In recent years,how to efficiently and accurately identify multi-model fake news has become more challenging.First,multi-model data provides more evidence but not all are equally important.Secondly,social structure information has proven to be effective in fake news detection and how to combine it while reducing the noise information is critical.Unfortunately,existing approaches fail to handle these problems.This paper proposes a multi-model fake news detection framework based on Tex-modal Dominance and fusing Multiple Multi-model Cues(TD-MMC),which utilizes three valuable multi-model clues:text-model importance,text-image complementary,and text-image inconsistency.TD-MMC is dominated by textural content and assisted by image information while using social network information to enhance text representation.To reduce the irrelevant social structure’s information interference,we use a unidirectional cross-modal attention mechanism to selectively learn the social structure’s features.A cross-modal attention mechanism is adopted to obtain text-image cross-modal features while retaining textual features to reduce the loss of important information.In addition,TD-MMC employs a new multi-model loss to improve the model’s generalization ability.Extensive experiments have been conducted on two public real-world English and Chinese datasets,and the results show that our proposed model outperforms the state-of-the-art methods on classification evaluation metrics. 展开更多
关键词 Fake news detection cross-modal attention mechanism multi-modal fusion social network transfer learning
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Generative Multi-Modal Mutual Enhancement Video Semantic Communications
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作者 Yuanle Chen Haobo Wang +3 位作者 Chunyu Liu Linyi Wang Jiaxin Liu Wei Wu 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第6期2985-3009,共25页
Recently,there have been significant advancements in the study of semantic communication in single-modal scenarios.However,the ability to process information in multi-modal environments remains limited.Inspired by the... Recently,there have been significant advancements in the study of semantic communication in single-modal scenarios.However,the ability to process information in multi-modal environments remains limited.Inspired by the research and applications of natural language processing across different modalities,our goal is to accurately extract frame-level semantic information from videos and ultimately transmit high-quality videos.Specifically,we propose a deep learning-basedMulti-ModalMutual Enhancement Video Semantic Communication system,called M3E-VSC.Built upon a VectorQuantized Generative AdversarialNetwork(VQGAN),our systemaims to leverage mutual enhancement among different modalities by using text as the main carrier of transmission.With it,the semantic information can be extracted fromkey-frame images and audio of the video and performdifferential value to ensure that the extracted text conveys accurate semantic information with fewer bits,thus improving the capacity of the system.Furthermore,a multi-frame semantic detection module is designed to facilitate semantic transitions during video generation.Simulation results demonstrate that our proposed model maintains high robustness in complex noise environments,particularly in low signal-to-noise ratio conditions,significantly improving the accuracy and speed of semantic transmission in video communication by approximately 50 percent. 展开更多
关键词 Generative adversarial networks multi-modal mutual enhancement video semantic transmission deep learning
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Drivers for Inter-city Innovation Networks Across Chinese Cities:Modelling Physical Versus Intangible Effects
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作者 GAO Yujie SCHERNGELL Thomas NEULÄNDTNER Martina 《Chinese Geographical Science》 SCIE CSCD 2024年第4期706-721,共16页
Cross-region innovation is widely recognized as an important source of the long-term regional innovation capacity.In the recent past,a growing number of studies has investigated the network structure and mechanisms of... Cross-region innovation is widely recognized as an important source of the long-term regional innovation capacity.In the recent past,a growing number of studies has investigated the network structure and mechanisms of cross-region innovation collaboration in various contexts.However,existing research mainly focuses on physical effects,such as geographical distance and high-speed railway connections.These studies ignore the intangible drivers in a changing environment,the more digitalized economy and the increasingly solidified innovation network structure.Thus,the focus of this study is on estimating determinants of innovation networks,especially on intangible drivers,which have been largely neglected so far.Using city-level data of Chinese patents(excluding Hong Kong,Macao,and Taiwan Province of China),we trace innovation networks across Chinese cities over a long period of time.By integrating a measure on Information and Communications Technology(ICT)development gap and network structural effects into the general proximity framework,this paper explores the changing mechanisms of Chinese innovation networks from a new perspective.The results show that the structure of cross-region innovation networks has changed in China.As mechanisms behind this development,the results confirm the increasingly important role of intangible drivers in Chinese inter-city innovation collaboration when controlling for effects of physical proximity,such as geographical distance.Since digitalization and coordinated development are the mainstream trends in China and other developing countries,these countries'inter-city innovation collaboration patterns will witness dramatic changes under the influence of intangible drivers. 展开更多
关键词 inter-city innovation network co-patents information and communications technology development network structural effect spatial interaction model China
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Enhancing Human Action Recognition with Adaptive Hybrid Deep Attentive Networks and Archerfish Optimization
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作者 Ahmad Yahiya Ahmad Bani Ahmad Jafar Alzubi +3 位作者 Sophers James Vincent Omollo Nyangaresi Chanthirasekaran Kutralakani Anguraju Krishnan 《Computers, Materials & Continua》 SCIE EI 2024年第9期4791-4812,共22页
In recent years,wearable devices-based Human Activity Recognition(HAR)models have received significant attention.Previously developed HAR models use hand-crafted features to recognize human activities,leading to the e... In recent years,wearable devices-based Human Activity Recognition(HAR)models have received significant attention.Previously developed HAR models use hand-crafted features to recognize human activities,leading to the extraction of basic features.The images captured by wearable sensors contain advanced features,allowing them to be analyzed by deep learning algorithms to enhance the detection and recognition of human actions.Poor lighting and limited sensor capabilities can impact data quality,making the recognition of human actions a challenging task.The unimodal-based HAR approaches are not suitable in a real-time environment.Therefore,an updated HAR model is developed using multiple types of data and an advanced deep-learning approach.Firstly,the required signals and sensor data are accumulated from the standard databases.From these signals,the wave features are retrieved.Then the extracted wave features and sensor data are given as the input to recognize the human activity.An Adaptive Hybrid Deep Attentive Network(AHDAN)is developed by incorporating a“1D Convolutional Neural Network(1DCNN)”with a“Gated Recurrent Unit(GRU)”for the human activity recognition process.Additionally,the Enhanced Archerfish Hunting Optimizer(EAHO)is suggested to fine-tune the network parameters for enhancing the recognition process.An experimental evaluation is performed on various deep learning networks and heuristic algorithms to confirm the effectiveness of the proposed HAR model.The EAHO-based HAR model outperforms traditional deep learning networks with an accuracy of 95.36,95.25 for recall,95.48 for specificity,and 95.47 for precision,respectively.The result proved that the developed model is effective in recognizing human action by taking less time.Additionally,it reduces the computation complexity and overfitting issue through using an optimization approach. 展开更多
关键词 Human action recognition multi-modal sensor data and signals adaptive hybrid deep attentive network enhanced archerfish hunting optimizer 1D convolutional neural network gated recurrent units
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Stackelberg Game for Wireless Powered and Backscattering Enabled Sensor Networks
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作者 Lyu Bin Cao Yi +2 位作者 Wang Shuai Guo Haiyan Hao Chengyao 《China Communications》 SCIE CSCD 2024年第3期189-204,共16页
This paper investigates a wireless powered and backscattering enabled sensor network based on the non-linear energy harvesting model, where the power beacon(PB) delivers energy signals to wireless sensors to enable th... This paper investigates a wireless powered and backscattering enabled sensor network based on the non-linear energy harvesting model, where the power beacon(PB) delivers energy signals to wireless sensors to enable their passive backscattering and active transmission to the access point(AP). We propose an efficient time scheduling scheme for network performance enhancement, based on which each sensor can always harvest energy from the PB over the entire block except its time slots allocated for passive and active information delivery. Considering the PB and wireless sensors are from two selfish service providers, we use the Stackelberg game to model the energy interaction among them. To address the non-convexity of the leader-level problem, we propose to decompose the original problem into two subproblems and solve them iteratively in an alternating manner. Specifically, the successive convex approximation, semi-definite relaxation(SDR) and variable substitution techniques are applied to find a nearoptimal solution. To evaluate the performance loss caused by the interaction between two providers, we further investigate the social welfare maximization problem. Numerical results demonstrate that compared to the benchmark schemes, the proposed scheme can achieve up to 35.4% and 38.7% utility gain for the leader and the follower, respectively. 展开更多
关键词 backscatter communication energy interaction stackelberg game wireless powered sensor network
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Pharmacologic mechanisms mining and prediction of Xiaoer Qixing Cha Formulae in the treatment of infantile functional dyspepsia based on chemical analysis by UPLC-QTOF/MS and interactive network pharmacology 被引量:1
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作者 Mei-Qi Wang Zeren Dawa +4 位作者 Yu-Feng Yao Fang-Le Liu Run-Jing Zhang Zi-Yuan Wang Chen-Chen Zhu 《TMR Modern Herbal Medicine》 2019年第2期48-63,共16页
Objective: To explore the main chemical compounds in Xiaoer Qixing Cha Formulae (XQCF), and investigate its mechanisms for the treatment of infantile functional dyspepsia (IFD). Methods: The chemical components were i... Objective: To explore the main chemical compounds in Xiaoer Qixing Cha Formulae (XQCF), and investigate its mechanisms for the treatment of infantile functional dyspepsia (IFD). Methods: The chemical components were identified by UPLC-QTOF/MS analytic technique. Targets of the compounds were screened from TCMSP and SWISS database, and disease targets were screened from OMIM and TTD online database. Candidate targets of compounds were mapped to the disease targets as predict therapeutic targets for XQCF. Several networks were constructed and analyzed by Cytoscape ver. 3.2.1. Meanwhile, prescription compatibility in XQCF was interpreted from the network perspective based on distribution of the number of targets. Furthermore, Gene Ontology (GO) enrichment analysis and KEGG pathway analysis were operated via Clue Go to illustrate complex relationships between the potential targets and pharmacological mechanisms. Results: A total of fifty-three compounds were recognized or tentatively characterized belonging to XQCF based on MS data and online chemical database. Sixty-three therapeutic targets were screened. AKT1, FOS, SLC6A4, COMT and 5-HT receptors were focused as therapeutic targets of XQCF. Pathways including carbohydrate digestion and absorption, serotonergic synapse, calcium signaling pathway and cAMP signaling pathway were predicted as significant regulatory pathways. The results indicated that the predicted targets and pathways related in brain-gut axis to a great extent, which could be potential pharmacological mechanism of XQCF for the treatment of IFD. Conclusions: The findings in this study provided the experimental and theoretical basis for further research for XQCF. Those also illustrated a reasonable method worth intensive study on pharmacodynamic mechanisms of TCM Formulae. 展开更多
关键词 Xiaoer Qixing Cha Formulae Infantile functional dyspepsia UPLC-QTOF/MS Chinese medicine Formulae interactive network pharmacology
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Effect of Apis mellifera on community composition of local pollinator bees and their pollination network in Qinling Mountains and surrounding areas
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作者 Cheng'en ZHONG Qingle XIE +1 位作者 Yaoyao SI Yalin ZHANG 《Entomotaxonomia》 CSCD 2024年第3期167-205,共39页
The Qinling Mountains, known for their rich vegetation and diverse pollinating insects, have seen a significant decline in bee species richness and abundance over recent decades, largely due to the introduction and sp... The Qinling Mountains, known for their rich vegetation and diverse pollinating insects, have seen a significant decline in bee species richness and abundance over recent decades, largely due to the introduction and spread of Apis mellifera. This decline has caused cascading effects on the region's community structure and ecosystem stability. To improve the protection of native bees in the natural and agricultural landscape of the Qinling Mountains and its surrounding areas, we investigated 33 sampling sites within three habitats: forest, forest-agriculture ecotones, and farmland. Using a generalized linear mixing model, t-test, and other data analysis methods, we explored the impact of Apis mellifera on local pollinator bee richness, abundance, and the pollination network in different habitats in these regional areas. The results show that(1)Apis mellifera significantly negatively affects the abundance and richness of wild pollinator bees,while Apis cerana abundance is also affected by beekeeping conditions.(2)There are significant negative effects of Apis mellifera on the community structure of pollinator bees in the Qinling Mountains and its surrounding areas: the Shannon-Wiener diversity index, Pielou evenness index, and Margalef richness index of bee communities at sites with Apis mellifera influence were significantly lower than those at sites without Apis mellifera influence.(3)The underlying driver of this effect is the monopolization of flowering resources by Apis mellifera. This species tends to visit flowering plants with large nectar sources, which constitute a significant portion of the local plant community. By maintaining a dominant role in the bee-plant pollination network, Apis mellifera competitively displaces native pollinator bees, reducing their access to floral resources. This ultimately leads to a reduction in local bee-plant interactions, decreasing the complexity and stability of the pollination network. These findings highlight the need for targeted conservation efforts to protect native pollinator species and maintain the ecological balance in the Qinling Mountains. 展开更多
关键词 Apis mellifera Pollinator bees Species richness ABUNDANCE interaction networks
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Unsupervised multi-modal image translation based on the squeeze-and-excitation mechanism and feature attention module
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作者 胡振涛 HU Chonghao +1 位作者 YANG Haoran SHUAI Weiwei 《High Technology Letters》 EI CAS 2024年第1期23-30,共8页
The unsupervised multi-modal image translation is an emerging domain of computer vision whose goal is to transform an image from the source domain into many diverse styles in the target domain.However,the multi-genera... The unsupervised multi-modal image translation is an emerging domain of computer vision whose goal is to transform an image from the source domain into many diverse styles in the target domain.However,the multi-generator mechanism is employed among the advanced approaches available to model different domain mappings,which results in inefficient training of neural networks and pattern collapse,leading to inefficient generation of image diversity.To address this issue,this paper introduces a multi-modal unsupervised image translation framework that uses a generator to perform multi-modal image translation.Specifically,firstly,the domain code is introduced in this paper to explicitly control the different generation tasks.Secondly,this paper brings in the squeeze-and-excitation(SE)mechanism and feature attention(FA)module.Finally,the model integrates multiple optimization objectives to ensure efficient multi-modal translation.This paper performs qualitative and quantitative experiments on multiple non-paired benchmark image translation datasets while demonstrating the benefits of the proposed method over existing technologies.Overall,experimental results have shown that the proposed method is versatile and scalable. 展开更多
关键词 multi-modal image translation generative adversarial network(GAN) squeezeand-excitation(SE)mechanism feature attention(FA)module
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Interactive English Reading Community Based on Social Network Sites
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作者 CHEN Min 《Sino-US English Teaching》 2015年第5期341-346,共6页
One of the major trends in the reform of English language teaching is the application of network technologies. This paper discusses the application of social network sites in building an interactive English reading co... One of the major trends in the reform of English language teaching is the application of network technologies. This paper discusses the application of social network sites in building an interactive English reading community under the guidance of the constructivist learning theory and its influence on the learners' English reading. This SNS-aided reading community puts the students as the center and the teacher the guide, embodying students' subjectivity, equality, and interactivity. The study shows that the interactive English reading community can motivate students to read, improve their reading skills, and thus develop a new SNS-aided English reading model for English learners. 展开更多
关键词 social network sites reading models interactive reading motivation of reading
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