Severe deterioration of liver function in patients can be characterized by coagulation disorders, jaundice, hepatic encephalopathy, ascites, and other symptoms. Severe liver injury can develop as acute liver failure, ...Severe deterioration of liver function in patients can be characterized by coagulation disorders, jaundice, hepatic encephalopathy, ascites, and other symptoms. Severe liver injury can develop as acute liver failure, subacute liver failure, acute-on-chronic liver failure, or further worsening of end-stage liver disease [1].展开更多
To establish the parsimonious model for blood glucose monitoring in patients with type 2 diabetes receiving oral hypoglycemic agent treatment. One hundred and fifty-nine adult Chinese type 2 diabetes patients were ran...To establish the parsimonious model for blood glucose monitoring in patients with type 2 diabetes receiving oral hypoglycemic agent treatment. One hundred and fifty-nine adult Chinese type 2 diabetes patients were randomized to receive rapid-acting or sustained-release gliclazide therapy for 12 weeks.展开更多
This paper presents the design and development of a health information system following the requirements of Spanish law as well as physicians and patients. In Spain, these systems are relatively new because, until rec...This paper presents the design and development of a health information system following the requirements of Spanish law as well as physicians and patients. In Spain, these systems are relatively new because, until recently, ownership of patients＇ medical records belonged to the health institution. The proposed system gives patients all the information about their medical records, online. The difference from other initiatives is that the hospital provides patients with information and the latter are responsible for its future use. Importantly, this application allows physicians to carry out a personalized and individualized monitoring and treatment of each patient. The tests were conducted with real patients, all with a chronic disease （to show each patient the personalized data）. They all expressed their appreciation of this application＇s usefulness, and obtained satisfaction level was very high. Thanks to having medical information stored on the proposed system, it can be provided to other specialists to improve the knowledgement about the patient.展开更多
In this paper, we introduce a system architecture for a patient centered mobile health monitoring (PCMHM) system that deploys different sensors to determine patients’ activities, medical conditions, and the cause of ...In this paper, we introduce a system architecture for a patient centered mobile health monitoring (PCMHM) system that deploys different sensors to determine patients’ activities, medical conditions, and the cause of an emergency event. This system combines and analyzes sensor data to produce the patients’ detailed health information in real-time. A central computational node with data analyzing capability is used for sensor data integration and analysis. In addition to medical sensors, surrounding environmental sensors are also utilized to enhance the interpretation of the data and to improve medical diagnosis. The PCMHM system has the ability to provide on-demand health information of patients via the Internet, track real-time daily activities and patients’ health condition. This system also includes the capability for assessing patients’ posture and fall detection.展开更多
BACKGROUND： Inflammatory reaction and the increased level of its accompanying active protein play an important role in the occurrence and development of cerebral infarction. C-reactive protein, fibrinogen and white b...BACKGROUND： Inflammatory reaction and the increased level of its accompanying active protein play an important role in the occurrence and development of cerebral infarction. C-reactive protein, fibrinogen and white blood cell, as the monitoring index of inflammatory reaction, are very important in the occurrence and development of acute cerebral infarction. OBJECTIVE： To make a comparison between patients with primary hypertension accompanied with acute cerebral infarction and with simple primary hypertension by observing the changes in plasma C-reactive protein and fibrinogen levels as well as white blood cell and differential counts and analyzing their significances. DESIGN ： Controlled observation SETTING ： Ward Building for VIP, Shenzhen Hospital, Peking University. PARTICIPANTS： Totally 133 patients with primary hypertension were selected from Ward Building for VIP, Shenzhen Hospital, Peking University during September 2003 to September 2005, The diagnostic criteria were based on the hypertension diagnosis criteria formulated by the 7^th World Health Organization-International Society of Hypertension Guidelines （WHO-ISH） in 1998. The informed consents were obtained from all the participants. The involved patients were assigned into two groups： primary hypertension group, in which, there were 65 patients with primary hypertension （ degree 2）, including 42 males and 23 females, with mean age of （61 ±14）years and mean blood pressure of （162.7±6.8）/（94.2±8.4） mm Hg （1 mm Hg =0.133 kPa）, and primary hypertension combined with cerebral infarction group, in which, there were 68 patients with primary hypertension combined with cerebral infarction （ meeting the diagnostic criteria formulated in the 4^th National Cerebrovascular Diseases Meeting in 1995 and diagnosed by skull CT or MRI to exclude the patients with lacunar infarction）, including 42 males and 26 females, with mean age of （56±15） years and mean blood pressure of （176.4±9.2）/（96.3±9.7） mm Hg. METHODS： Plasm C-reactive protein and fibrinogen levels, and white blood cell and differential counts of patients in the two groups were examined 24 hours after stroke. The above indexes were re-examined in the primary hypertension combined with cerebral infarction group 72 hours after stroke. White blood cell and differential counts were performed with laser method （East Asia FE-95001 RAM-1, Japan）. The level of C-reactive protein was measured with turbidimetry （BNII Automatic Systems For Analysis, USA）. The level of fibrinogen was measured with algorithm method when prothrombin time was normal and with Clauss method when prothrombin time was abnormal （ACL Automatic Coagulation Analyzer, USA）. MAIN OUTCOME MEASURES： The plasm C-reactive protein and flbrinogen levels, and white blood cell and differential counts 24 hours after stroke in two groups and 72 hours after stroke in primary hypertension combined with cerebral infarction group. RESULTS： All the 133 involved patients participated in the result analysis. The plasm C-reactive protein and fibrinogen levels, and white blood cell and neutrophil counts in patients with primary hypertension were all within the normal range. The plasm C-reactive protein and fibrinogen levels, and white blood cell and neu- trophil counts in patients with primary hypertension combined with cerebral infarction were significantly higher than those in patients with primary hypertension 24 hours after stroke and 72 hours after stroke respectively[24 hours after stroke：（32.12±11.76） mg/L vs. （5.02±3.21 ） mg/L;（4.64±0.75） g/L vs. （3.12±0.49） g/L; （9.32±81）×10^9 L^- 1 vs. （5.78±1.32）×10^9L^- 1 （7.85±2.38）×10^9 L^- 1 vs.（3.49±1.28）×10^9 L^-1,t =7.094, 5.759,4.106,5.491, respectively,all P〈 0.01; 72 hours after stroke： （47.62±18.43） mg/L vs. （32.12±11.76） mg/L; （5.08±0.82） g/L vs. （4.64±0.75） g/L, t =2.864,2.220, respectively, both P 〈 0.05]. CONCLUSION： The increase in fibrinogen level and white blood cell count are the important index in monitoring primary hypertension combined with acute cerebral infarction. The increase in plasm C-reactive protein and fibrinogen levels 72 hours after stroke indicates that plasma C-reactive protein and fibrinogen are very important in the development of disease.展开更多
Self-monitoring of blood glucose(SMBG)is critical for gestational diabetes mellitus(GDM)care.However,there are several hurdles to its practice during the coronavirus disease 2019(COVID-19)pandemic in GDM patients in l...Self-monitoring of blood glucose(SMBG)is critical for gestational diabetes mellitus(GDM)care.However,there are several hurdles to its practice during the coronavirus disease 2019(COVID-19)pandemic in GDM patients in low-and middle-income countries when GDM care recommendations emphasize telemedicine-based care.Based on available knowledge,this letter proposes the following barriers to SMBG in these GDM patients during the ongoing COVID-19 pandemic:Poor internet connectivity,affordability of SMBG and digital applications to connect with healthcare providers,government-imposed social mobility restriction,psychological stress,and mental health conditions.Nevertheless,definitive evidence will only be acquired from rigorous research.展开更多
IoT technology has emerged as a valuable tool in modern healthcare, providing real-time monitoring of patients, effective management of healthcare, and proper administration of patient information. The proposed system...IoT technology has emerged as a valuable tool in modern healthcare, providing real-time monitoring of patients, effective management of healthcare, and proper administration of patient information. The proposed system aims to develop a system that can prevent backward blood flow from stopping saline fluid, as well as monitor the temperature, heart rate, and oxygen level of patients by using multiple sensors like weight, temperature and heart rate, etc. Additionally, the proposed system can monitor the room temperature and humidity for contributing to the patient’s overall comfort. In emergency situations, it includes an emergency push button for quick alert medical staff and initiates timely interventions. It is designed to support nurses and doctors in monitoring patients and providing timely interventions to prevent complications.展开更多
探究基于“-TT”结构经监护仪腹内压监测法降低重症患者喂养不耐受发生率的效果。选取2022年8月—2023年8月四川省自贡市第四人民医院抢救监护室(emergency intensive care unit,EICU)60例重症需行肠内营养(enteral nutrition,EN)支持...探究基于“-TT”结构经监护仪腹内压监测法降低重症患者喂养不耐受发生率的效果。选取2022年8月—2023年8月四川省自贡市第四人民医院抢救监护室(emergency intensive care unit,EICU)60例重症需行肠内营养(enteral nutrition,EN)支持的患者作为研究对象,采用随机数字表法将患者分为参照组和试验组,每组各30例。参照组实施常规EN管理,试验组在参照组基础上实施基于“-TT”结构经监护仪腹内压监测法,对比两组患者的喂养不耐受发生率。结果显示,与参照组相比,试验组喂养不耐受发生率较低(P<0.05);试验组达到目标喂养量时间较短(P<0.05);试验组EICU停留时间较短(P<0.05)。研究发现,于EICU重症需行EN支持患者的管理中,基于“-TT”结构经监护仪腹内压监测法具有一定的临床应用价值,通过对患者腹压变化的实时监测,可以及时调整喂养方案,降低其喂养不耐受发生率,缩短患者达到目标喂养量的时间,改善患者预后,值得借鉴。展开更多
基金supported by grants from Key Research and Development Project of Department of Science and Technology of Zhejiang Province(2017C03051)Science Fund for Creative Research Groups of the National Natural Science Foundation of China(81721091)
文摘Severe deterioration of liver function in patients can be characterized by coagulation disorders, jaundice, hepatic encephalopathy, ascites, and other symptoms. Severe liver injury can develop as acute liver failure, subacute liver failure, acute-on-chronic liver failure, or further worsening of end-stage liver disease [1].
文摘To establish the parsimonious model for blood glucose monitoring in patients with type 2 diabetes receiving oral hypoglycemic agent treatment. One hundred and fifty-nine adult Chinese type 2 diabetes patients were randomized to receive rapid-acting or sustained-release gliclazide therapy for 12 weeks.
文摘This paper presents the design and development of a health information system following the requirements of Spanish law as well as physicians and patients. In Spain, these systems are relatively new because, until recently, ownership of patients＇ medical records belonged to the health institution. The proposed system gives patients all the information about their medical records, online. The difference from other initiatives is that the hospital provides patients with information and the latter are responsible for its future use. Importantly, this application allows physicians to carry out a personalized and individualized monitoring and treatment of each patient. The tests were conducted with real patients, all with a chronic disease （to show each patient the personalized data）. They all expressed their appreciation of this application＇s usefulness, and obtained satisfaction level was very high. Thanks to having medical information stored on the proposed system, it can be provided to other specialists to improve the knowledgement about the patient.
文摘In this paper, we introduce a system architecture for a patient centered mobile health monitoring (PCMHM) system that deploys different sensors to determine patients’ activities, medical conditions, and the cause of an emergency event. This system combines and analyzes sensor data to produce the patients’ detailed health information in real-time. A central computational node with data analyzing capability is used for sensor data integration and analysis. In addition to medical sensors, surrounding environmental sensors are also utilized to enhance the interpretation of the data and to improve medical diagnosis. The PCMHM system has the ability to provide on-demand health information of patients via the Internet, track real-time daily activities and patients’ health condition. This system also includes the capability for assessing patients’ posture and fall detection.
文摘BACKGROUND： Inflammatory reaction and the increased level of its accompanying active protein play an important role in the occurrence and development of cerebral infarction. C-reactive protein, fibrinogen and white blood cell, as the monitoring index of inflammatory reaction, are very important in the occurrence and development of acute cerebral infarction. OBJECTIVE： To make a comparison between patients with primary hypertension accompanied with acute cerebral infarction and with simple primary hypertension by observing the changes in plasma C-reactive protein and fibrinogen levels as well as white blood cell and differential counts and analyzing their significances. DESIGN ： Controlled observation SETTING ： Ward Building for VIP, Shenzhen Hospital, Peking University. PARTICIPANTS： Totally 133 patients with primary hypertension were selected from Ward Building for VIP, Shenzhen Hospital, Peking University during September 2003 to September 2005, The diagnostic criteria were based on the hypertension diagnosis criteria formulated by the 7^th World Health Organization-International Society of Hypertension Guidelines （WHO-ISH） in 1998. The informed consents were obtained from all the participants. The involved patients were assigned into two groups： primary hypertension group, in which, there were 65 patients with primary hypertension （ degree 2）, including 42 males and 23 females, with mean age of （61 ±14）years and mean blood pressure of （162.7±6.8）/（94.2±8.4） mm Hg （1 mm Hg =0.133 kPa）, and primary hypertension combined with cerebral infarction group, in which, there were 68 patients with primary hypertension combined with cerebral infarction （ meeting the diagnostic criteria formulated in the 4^th National Cerebrovascular Diseases Meeting in 1995 and diagnosed by skull CT or MRI to exclude the patients with lacunar infarction）, including 42 males and 26 females, with mean age of （56±15） years and mean blood pressure of （176.4±9.2）/（96.3±9.7） mm Hg. METHODS： Plasm C-reactive protein and fibrinogen levels, and white blood cell and differential counts of patients in the two groups were examined 24 hours after stroke. The above indexes were re-examined in the primary hypertension combined with cerebral infarction group 72 hours after stroke. White blood cell and differential counts were performed with laser method （East Asia FE-95001 RAM-1, Japan）. The level of C-reactive protein was measured with turbidimetry （BNII Automatic Systems For Analysis, USA）. The level of fibrinogen was measured with algorithm method when prothrombin time was normal and with Clauss method when prothrombin time was abnormal （ACL Automatic Coagulation Analyzer, USA）. MAIN OUTCOME MEASURES： The plasm C-reactive protein and flbrinogen levels, and white blood cell and differential counts 24 hours after stroke in two groups and 72 hours after stroke in primary hypertension combined with cerebral infarction group. RESULTS： All the 133 involved patients participated in the result analysis. The plasm C-reactive protein and fibrinogen levels, and white blood cell and neutrophil counts in patients with primary hypertension were all within the normal range. The plasm C-reactive protein and fibrinogen levels, and white blood cell and neu- trophil counts in patients with primary hypertension combined with cerebral infarction were significantly higher than those in patients with primary hypertension 24 hours after stroke and 72 hours after stroke respectively[24 hours after stroke：（32.12±11.76） mg/L vs. （5.02±3.21 ） mg/L;（4.64±0.75） g/L vs. （3.12±0.49） g/L; （9.32±81）×10^9 L^- 1 vs. （5.78±1.32）×10^9L^- 1 （7.85±2.38）×10^9 L^- 1 vs.（3.49±1.28）×10^9 L^-1,t =7.094, 5.759,4.106,5.491, respectively,all P〈 0.01; 72 hours after stroke： （47.62±18.43） mg/L vs. （32.12±11.76） mg/L; （5.08±0.82） g/L vs. （4.64±0.75） g/L, t =2.864,2.220, respectively, both P 〈 0.05]. CONCLUSION： The increase in fibrinogen level and white blood cell count are the important index in monitoring primary hypertension combined with acute cerebral infarction. The increase in plasm C-reactive protein and fibrinogen levels 72 hours after stroke indicates that plasma C-reactive protein and fibrinogen are very important in the development of disease.
文摘Self-monitoring of blood glucose(SMBG)is critical for gestational diabetes mellitus(GDM)care.However,there are several hurdles to its practice during the coronavirus disease 2019(COVID-19)pandemic in GDM patients in low-and middle-income countries when GDM care recommendations emphasize telemedicine-based care.Based on available knowledge,this letter proposes the following barriers to SMBG in these GDM patients during the ongoing COVID-19 pandemic:Poor internet connectivity,affordability of SMBG and digital applications to connect with healthcare providers,government-imposed social mobility restriction,psychological stress,and mental health conditions.Nevertheless,definitive evidence will only be acquired from rigorous research.
文摘IoT technology has emerged as a valuable tool in modern healthcare, providing real-time monitoring of patients, effective management of healthcare, and proper administration of patient information. The proposed system aims to develop a system that can prevent backward blood flow from stopping saline fluid, as well as monitor the temperature, heart rate, and oxygen level of patients by using multiple sensors like weight, temperature and heart rate, etc. Additionally, the proposed system can monitor the room temperature and humidity for contributing to the patient’s overall comfort. In emergency situations, it includes an emergency push button for quick alert medical staff and initiates timely interventions. It is designed to support nurses and doctors in monitoring patients and providing timely interventions to prevent complications.
文摘探究基于“-TT”结构经监护仪腹内压监测法降低重症患者喂养不耐受发生率的效果。选取2022年8月—2023年8月四川省自贡市第四人民医院抢救监护室(emergency intensive care unit,EICU)60例重症需行肠内营养(enteral nutrition,EN)支持的患者作为研究对象,采用随机数字表法将患者分为参照组和试验组,每组各30例。参照组实施常规EN管理,试验组在参照组基础上实施基于“-TT”结构经监护仪腹内压监测法,对比两组患者的喂养不耐受发生率。结果显示,与参照组相比,试验组喂养不耐受发生率较低(P<0.05);试验组达到目标喂养量时间较短(P<0.05);试验组EICU停留时间较短(P<0.05)。研究发现,于EICU重症需行EN支持患者的管理中,基于“-TT”结构经监护仪腹内压监测法具有一定的临床应用价值,通过对患者腹压变化的实时监测,可以及时调整喂养方案,降低其喂养不耐受发生率,缩短患者达到目标喂养量的时间,改善患者预后,值得借鉴。
