When a new user accesses the CDMA system, the load will change drastically, and therefore, the advanced outer loop power control (OLPC) technology has to be adopted to enrich the target signal interference ratio (S...When a new user accesses the CDMA system, the load will change drastically, and therefore, the advanced outer loop power control (OLPC) technology has to be adopted to enrich the target signal interference ratio (Silt) and improve the system performance. The existing problems about DS-CDMA outer loop power control for multi-service are introduced and the power control theoretical model is analyzed. System simulation is adopted on how to obtain the theoretical performance and parameter optimization of the power control algorithm. The OLPC algorithm is improved and the performance comparisons between the old algorithm and the improved algorithm are given. The results show good performance of the improved OLPC algorithm and prove the validity of the improved method for multi-service.展开更多
Multi-service aggregated transmission is the direction of IP network. Providing different Quality of Service (QoS) assurance for different services has become a crucial problem in future network. Admission control is ...Multi-service aggregated transmission is the direction of IP network. Providing different Quality of Service (QoS) assurance for different services has become a crucial problem in future network. Admission control is a vital function for multi-service IP network. This paper proposes a novel fuzzy admission control scheme based on coarse granularity service-aware technique. Different service has discriminative sensitivity to the same QoS characteristic parameter in general. The traffic class can be perceived by the service request parameter and the proposed QoS function. And requirements of dif- ferent applications can be met by maintaining the life parameter. From simulation results, the proposed scheme shows a better QoS provisioning than those traditional fuzzy logic based methods under the same admission probability.展开更多
This paper mainly studies the problem of multi-task assignment of providers in port logistics service supply chain.As a core enterprise,port plays the role of logistics service integrator.With the continuous developme...This paper mainly studies the problem of multi-task assignment of providers in port logistics service supply chain.As a core enterprise,port plays the role of logistics service integrator.With the continuous development of industrial integration,logistics service providers not only provide one kind of logistics service,but also develop into composite suppliers who capable of providing a variety of logistics services.This paper studies the task assignment problem of multi-service capability providers in the port logistics service supply chain.The two-stage logistics service provider task assignment model was built,which is based on the mixed evaluation method(including MOORA and FMEA)and the multi-objective planning method.Eventually,the effectiveness of the model method was verified by combining with an example.展开更多
Providing the required metrics for different service respectively is a basic characteristic in multi-service networks. The different service can be accessed and forwarded differently to provide the different transmiss...Providing the required metrics for different service respectively is a basic characteristic in multi-service networks. The different service can be accessed and forwarded differently to provide the different transmission performance. The state information between admission control and scheduling can be exchanged each other by the defined correlation coefficient to adjust the flow distribution in progress. The priority queue length measured by scheduler implicitly can describe the priority flows load. And the fair rate can describe the non-priority flows load. Different admission decision will be made according to the state of scheduler to assure the time-delay upper threshold for the priority flows under heavy load and the fairness for elastic flows in light load, respectively. The stability condition was conduced and proved. Simulation results show the policy can ensure both the delay for the priority flows and the minimal throughput for non-priority flows.展开更多
This paper first gives a SCP abstract model, then SCP’s overload detection and maximum processing capability are discussed quantitatively. Based upon dynamic adjustment, a new two-level SCP overload control algorithm...This paper first gives a SCP abstract model, then SCP’s overload detection and maximum processing capability are discussed quantitatively. Based upon dynamic adjustment, a new two-level SCP overload control algorithm is proposed. Theoretical analysis and simulation prove the algorithm’s effectiveness and fairness.展开更多
Multi-service SDH networks support both packet- and circuit-switched traffic. Optimal design of such a network means to guarantee the circuit connections and configure a logical packet-switched topology with lowest co...Multi-service SDH networks support both packet- and circuit-switched traffic. Optimal design of such a network means to guarantee the circuit connections and configure a logical packet-switched topology with lowest congestion. This letter first formulates the problem as a mixed integer linear programming, which achieves optimal solution but has high computation. Then a heuristic algorithm is proposed to yield near-optimal solution efficiently. Performance of the algorithm is verified by an example.展开更多
A prepaid subscriber is allowed to simultaneously implement multiple services in online charging mechanism of IP Multimedia Subsystem (IMS). It is a noteworthy discussion to effectively distribute the limited account ...A prepaid subscriber is allowed to simultaneously implement multiple services in online charging mechanism of IP Multimedia Subsystem (IMS). It is a noteworthy discussion to effectively distribute the limited account resources among concurrent services. An account-sharing algorithm is proposed for multi-services,which introduces resource reclamation and redistribution processes based on the resource reservation of standard specifications and dynamically adjusts them according to the changes of Quality of Service (QoS). Three performance indexes are investigated in the simulation experiments, which are average number of accommodated sessions, average number of completed ses- sions, and average number of iterations per accommodated session. The results show that in the normal QoS level, the three indexes of the proposed algorithm averagely increase by 18.7%, 5.4%, and 3.1% compared with the Prepaid Credit Distribution (PCD) algorithm, and by 2.1%, 1.0%, and 1.8% compared with the Prepaid Credit Reclaim (PCR) algorithm. In the poor QoS level, the performance advantages are greater, which averagely increase by 29.1%, 7.1%, and 2.8% compared with PCD, and by 9.4%, 4.1%, and 3.6% compared with PCR.展开更多
With the challenge of great growing of services diversity,service-oriented supporting ability is required by current high-speed passive optical network( PON). Aimed at enhancing the quality of service( Qo S) brought b...With the challenge of great growing of services diversity,service-oriented supporting ability is required by current high-speed passive optical network( PON). Aimed at enhancing the quality of service( Qo S) brought by diversified-services,this study proposes an echo state network( ESN)based multi-service awareness mechanism in 10-Gigabite ethernet passive optical network( 10GEPON). In the proposed approach,distributed architecture is adopted to realize this ESN based multi-service awareness. According to the network architecture of 10G-EPON,where a main ESN is running in OLT and a number of ESN agents works in ONUs. The main-ESN plays the main function of service-awareness from the total view of various kinds of services in 10G-EPON system,by full ESN training. Then,the reservoir information of well-trained ESN in OLT will be broadcasted to all ONUs and those ESN agents working in ONUs are allowed to conduct independent service-awareness function. Thus,resources allocation and transport policy are both determined only in ONUs. Simulation results show that the proposed mechanism is able to better support the ability of multiple services.展开更多
软件定义广域网(Software Defined Wide Area Network,SD-WAN)作为被应用于广域网连接的新型网络技术,使用混合链路为广域网流量提供多条Overlay转发路径,配合智能应用选路等技术为网络流量提供最优路径动态选择的能力。提出了一种基于...软件定义广域网(Software Defined Wide Area Network,SD-WAN)作为被应用于广域网连接的新型网络技术,使用混合链路为广域网流量提供多条Overlay转发路径,配合智能应用选路等技术为网络流量提供最优路径动态选择的能力。提出了一种基于混合链路多Overlay隧道实现网络规模解耦下快速路由切换的新型设计,在广域网链路中断后提供路由收敛时间确定性上界保证,给出关键的数据结构及工作流程,对相关工程实施具备较好的指导作用。展开更多
Chronic myeloid leukemia(CML)is a hematopoietic myeloproliferative disorder.The Chinese prescription Danggui Longhui Wan(DGLHW)has been utilized in CML treatment,but its underlying mechanisms remain unclear.In this st...Chronic myeloid leukemia(CML)is a hematopoietic myeloproliferative disorder.The Chinese prescription Danggui Longhui Wan(DGLHW)has been utilized in CML treatment,but its underlying mechanisms remain unclear.In this study,we gathered 794 constituents,1249 drug targets,1654 disease genes and 129 intersection genes.GO and KEGG were used to analyze the function of these genes.Compatibility of prescription study showed that monarch drug,minister drug,assistant and guide drug played a synergistic role in the treatment of CML.In addition,we obtained 20 hub genes and 12 key components.Molecular docking indicated that the main compounds and core proteins had good binding ability.The results of this study also showed that DGLHW might play a role in the treatment of CML by affecting MAPK,PI3K/AKT,FoxO and p53 signaling pathways.展开更多
Background:To initially clarify the potential therapeutic targets and pharmacological mechanism regarding Gualou Qumai Wan(GQW),a kind of traditional Chinese medicine(TCM),in clear cell renal cell carcinoma(ccRCC)by v...Background:To initially clarify the potential therapeutic targets and pharmacological mechanism regarding Gualou Qumai Wan(GQW),a kind of traditional Chinese medicine(TCM),in clear cell renal cell carcinoma(ccRCC)by virtue of the network pharmacology analysis and molecular docking analysis.Methods:The screening of bioactive components and targets of GQW was based on the Traditional Chinese Medicine System Pharmacology(TCMSP)and the UniProt platform served for standardizing their targets.Online Mendelian Inheritance in Man(OMIM),PharmGkb,TTD,DrugBank and GeneCards databases were searched to collect the disease targets of ccRCC.Cytoscape assisted in constructing herb-compound-target(H-C-T)networks.The STRING database was searched for constructing the target protein-protein interaction(PPI)networks,while the R programming language served for analyzing GO functional terms and the KEGG pathways related to potential targets.Analyses of core genes related to survival and tumor microenvironment(TME)were conducted respectively based on the GEPIA2 database and TIMER 2.0 database.Human Protein Atlas(HPA)and The Cancer Genome Atlas(TCGA)helped to obtain core genes’protein expression as well as transcriptome expression level.Autodock Vina software validated the molecular docking regarding GQW components and pivotal targets.Results:The constructed H-C-T networks mainly had 33 compounds and 65 targets.A topological analysis of the PPI network identified that ESR1,AKT1,HIF1A,PTGS2,TP53 and VEGFA serve as core targets in the way GQW affects ccRCC.According to the GO and KEGG pathway enrichment analyses,the effects of GQW are mediated by genes related to hypoxia and oxidative stress as well as the Chemical carcinogenesis-receptor activation and PI3K-Akt signaling pathways.AKT1 shows a close relation to the recruitment of various immune cells and can remarkably affect disease prognosis according to reports.Molecular docking and molecular dynamics simulations showed that diosgenin has higher affinity with core targets.Conclusion:The study makes a comprehensive explanation of the biological activity,potential targets,as well as molecular mechanism regarding GQW against ccRCC,which promisingly assists in revealing the action mechanism of TCM formulae in disease treatment and the respective and scientific basis.展开更多
文章研究了软件定义广域网(Software-Defined Wide Area Networking,SD-WAN)结合边缘智能在瓦楞纸板生产车间中的应用。该研究的目标是提升瓦楞纸板生产车间的网络性能、安全性和管理效率。通过使用SD-WAN技术,该车间可以实现网络虚拟...文章研究了软件定义广域网(Software-Defined Wide Area Networking,SD-WAN)结合边缘智能在瓦楞纸板生产车间中的应用。该研究的目标是提升瓦楞纸板生产车间的网络性能、安全性和管理效率。通过使用SD-WAN技术,该车间可以实现网络虚拟化、智能路由和实时监控,从而提高网络通信的可靠性和稳定性。SD-WAN与边缘智能的结合使网络资源得以高效利用,优化路由决策,并实现主动的网络管理。该研究对于推动工业环境中的网络技术发展具有重要意义,为瓦楞纸板制造业提供了提高生产效率、降低成本以及提升运营灵活性的机遇。展开更多
基金the National Natural Science Foundation of China (60532030).
文摘When a new user accesses the CDMA system, the load will change drastically, and therefore, the advanced outer loop power control (OLPC) technology has to be adopted to enrich the target signal interference ratio (Silt) and improve the system performance. The existing problems about DS-CDMA outer loop power control for multi-service are introduced and the power control theoretical model is analyzed. System simulation is adopted on how to obtain the theoretical performance and parameter optimization of the power control algorithm. The OLPC algorithm is improved and the performance comparisons between the old algorithm and the improved algorithm are given. The results show good performance of the improved OLPC algorithm and prove the validity of the improved method for multi-service.
基金the High-tech Project of Jiangsu Province (No.BG2003001).
文摘Multi-service aggregated transmission is the direction of IP network. Providing different Quality of Service (QoS) assurance for different services has become a crucial problem in future network. Admission control is a vital function for multi-service IP network. This paper proposes a novel fuzzy admission control scheme based on coarse granularity service-aware technique. Different service has discriminative sensitivity to the same QoS characteristic parameter in general. The traffic class can be perceived by the service request parameter and the proposed QoS function. And requirements of dif- ferent applications can be met by maintaining the life parameter. From simulation results, the proposed scheme shows a better QoS provisioning than those traditional fuzzy logic based methods under the same admission probability.
文摘This paper mainly studies the problem of multi-task assignment of providers in port logistics service supply chain.As a core enterprise,port plays the role of logistics service integrator.With the continuous development of industrial integration,logistics service providers not only provide one kind of logistics service,but also develop into composite suppliers who capable of providing a variety of logistics services.This paper studies the task assignment problem of multi-service capability providers in the port logistics service supply chain.The two-stage logistics service provider task assignment model was built,which is based on the mixed evaluation method(including MOORA and FMEA)and the multi-objective planning method.Eventually,the effectiveness of the model method was verified by combining with an example.
基金Supported by the National Natural Science Foundation of China (No. 60872002, 61003237)the Open Research Foundation of National Mobile Communications Research Lab, Southeast University, China (W200912)the Natural Science Foundation of Nantong Universty (No. 08Z025)
文摘Providing the required metrics for different service respectively is a basic characteristic in multi-service networks. The different service can be accessed and forwarded differently to provide the different transmission performance. The state information between admission control and scheduling can be exchanged each other by the defined correlation coefficient to adjust the flow distribution in progress. The priority queue length measured by scheduler implicitly can describe the priority flows load. And the fair rate can describe the non-priority flows load. Different admission decision will be made according to the state of scheduler to assure the time-delay upper threshold for the priority flows under heavy load and the fairness for elastic flows in light load, respectively. The stability condition was conduced and proved. Simulation results show the policy can ensure both the delay for the priority flows and the minimal throughput for non-priority flows.
基金Supported by 863 high technology projectthe National Natural Science Foundation of ChinaKey Foundation of Ministry of Posts and Telecommunications
文摘This paper first gives a SCP abstract model, then SCP’s overload detection and maximum processing capability are discussed quantitatively. Based upon dynamic adjustment, a new two-level SCP overload control algorithm is proposed. Theoretical analysis and simulation prove the algorithm’s effectiveness and fairness.
文摘Multi-service SDH networks support both packet- and circuit-switched traffic. Optimal design of such a network means to guarantee the circuit connections and configure a logical packet-switched topology with lowest congestion. This letter first formulates the problem as a mixed integer linear programming, which achieves optimal solution but has high computation. Then a heuristic algorithm is proposed to yield near-optimal solution efficiently. Performance of the algorithm is verified by an example.
基金Supported by the National Natural Science Fund for Distinguished Young Scholars (No.60525110)the National 973 Program (No.2007CB307100, No.2007CB 307103)the Development Fund Project for Elec-tronic and Information Industry (Mobile Service and Application System Based on 3G)
文摘A prepaid subscriber is allowed to simultaneously implement multiple services in online charging mechanism of IP Multimedia Subsystem (IMS). It is a noteworthy discussion to effectively distribute the limited account resources among concurrent services. An account-sharing algorithm is proposed for multi-services,which introduces resource reclamation and redistribution processes based on the resource reservation of standard specifications and dynamically adjusts them according to the changes of Quality of Service (QoS). Three performance indexes are investigated in the simulation experiments, which are average number of accommodated sessions, average number of completed ses- sions, and average number of iterations per accommodated session. The results show that in the normal QoS level, the three indexes of the proposed algorithm averagely increase by 18.7%, 5.4%, and 3.1% compared with the Prepaid Credit Distribution (PCD) algorithm, and by 2.1%, 1.0%, and 1.8% compared with the Prepaid Credit Reclaim (PCR) algorithm. In the poor QoS level, the performance advantages are greater, which averagely increase by 29.1%, 7.1%, and 2.8% compared with PCD, and by 9.4%, 4.1%, and 3.6% compared with PCR.
基金Supported by the National High Technology Research and Development Programme of China(No.2012AA050804)
文摘With the challenge of great growing of services diversity,service-oriented supporting ability is required by current high-speed passive optical network( PON). Aimed at enhancing the quality of service( Qo S) brought by diversified-services,this study proposes an echo state network( ESN)based multi-service awareness mechanism in 10-Gigabite ethernet passive optical network( 10GEPON). In the proposed approach,distributed architecture is adopted to realize this ESN based multi-service awareness. According to the network architecture of 10G-EPON,where a main ESN is running in OLT and a number of ESN agents works in ONUs. The main-ESN plays the main function of service-awareness from the total view of various kinds of services in 10G-EPON system,by full ESN training. Then,the reservoir information of well-trained ESN in OLT will be broadcasted to all ONUs and those ESN agents working in ONUs are allowed to conduct independent service-awareness function. Thus,resources allocation and transport policy are both determined only in ONUs. Simulation results show that the proposed mechanism is able to better support the ability of multiple services.
文摘软件定义广域网(Software Defined Wide Area Network,SD-WAN)作为被应用于广域网连接的新型网络技术,使用混合链路为广域网流量提供多条Overlay转发路径,配合智能应用选路等技术为网络流量提供最优路径动态选择的能力。提出了一种基于混合链路多Overlay隧道实现网络规模解耦下快速路由切换的新型设计,在广域网链路中断后提供路由收敛时间确定性上界保证,给出关键的数据结构及工作流程,对相关工程实施具备较好的指导作用。
文摘Chronic myeloid leukemia(CML)is a hematopoietic myeloproliferative disorder.The Chinese prescription Danggui Longhui Wan(DGLHW)has been utilized in CML treatment,but its underlying mechanisms remain unclear.In this study,we gathered 794 constituents,1249 drug targets,1654 disease genes and 129 intersection genes.GO and KEGG were used to analyze the function of these genes.Compatibility of prescription study showed that monarch drug,minister drug,assistant and guide drug played a synergistic role in the treatment of CML.In addition,we obtained 20 hub genes and 12 key components.Molecular docking indicated that the main compounds and core proteins had good binding ability.The results of this study also showed that DGLHW might play a role in the treatment of CML by affecting MAPK,PI3K/AKT,FoxO and p53 signaling pathways.
基金supported by Weifang Health Commission Traditional Chinese Medicine Research Project Plan(WFZYY2023-1-004).
文摘Background:To initially clarify the potential therapeutic targets and pharmacological mechanism regarding Gualou Qumai Wan(GQW),a kind of traditional Chinese medicine(TCM),in clear cell renal cell carcinoma(ccRCC)by virtue of the network pharmacology analysis and molecular docking analysis.Methods:The screening of bioactive components and targets of GQW was based on the Traditional Chinese Medicine System Pharmacology(TCMSP)and the UniProt platform served for standardizing their targets.Online Mendelian Inheritance in Man(OMIM),PharmGkb,TTD,DrugBank and GeneCards databases were searched to collect the disease targets of ccRCC.Cytoscape assisted in constructing herb-compound-target(H-C-T)networks.The STRING database was searched for constructing the target protein-protein interaction(PPI)networks,while the R programming language served for analyzing GO functional terms and the KEGG pathways related to potential targets.Analyses of core genes related to survival and tumor microenvironment(TME)were conducted respectively based on the GEPIA2 database and TIMER 2.0 database.Human Protein Atlas(HPA)and The Cancer Genome Atlas(TCGA)helped to obtain core genes’protein expression as well as transcriptome expression level.Autodock Vina software validated the molecular docking regarding GQW components and pivotal targets.Results:The constructed H-C-T networks mainly had 33 compounds and 65 targets.A topological analysis of the PPI network identified that ESR1,AKT1,HIF1A,PTGS2,TP53 and VEGFA serve as core targets in the way GQW affects ccRCC.According to the GO and KEGG pathway enrichment analyses,the effects of GQW are mediated by genes related to hypoxia and oxidative stress as well as the Chemical carcinogenesis-receptor activation and PI3K-Akt signaling pathways.AKT1 shows a close relation to the recruitment of various immune cells and can remarkably affect disease prognosis according to reports.Molecular docking and molecular dynamics simulations showed that diosgenin has higher affinity with core targets.Conclusion:The study makes a comprehensive explanation of the biological activity,potential targets,as well as molecular mechanism regarding GQW against ccRCC,which promisingly assists in revealing the action mechanism of TCM formulae in disease treatment and the respective and scientific basis.
文摘文章研究了软件定义广域网(Software-Defined Wide Area Networking,SD-WAN)结合边缘智能在瓦楞纸板生产车间中的应用。该研究的目标是提升瓦楞纸板生产车间的网络性能、安全性和管理效率。通过使用SD-WAN技术,该车间可以实现网络虚拟化、智能路由和实时监控,从而提高网络通信的可靠性和稳定性。SD-WAN与边缘智能的结合使网络资源得以高效利用,优化路由决策,并实现主动的网络管理。该研究对于推动工业环境中的网络技术发展具有重要意义,为瓦楞纸板制造业提供了提高生产效率、降低成本以及提升运营灵活性的机遇。